...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 4076838 | Benzocycloheptene-2-acetic acids This invention provides new compounds of formula I, ##STR1## wherein R1 is hydrogen or alkyl of 1 or 2 carbon atoms; R2 is hydrogen or halogen of atomic number from 9 to 35; A. I. each of R3 and R4 is hydrogen, or Ii... | 02/28/1978 |
| 4073922 | Treatment of rheumatoid arthritis and related diseases It is believed that rheumatoid arthritis and related collagen and auto-immune diseases are an infection and that various species of free-living (limax) amoebae are the aetiological agent of these diseases. It has been discovered that clotrimazole bis-phe... | 02/14/1978 |
| 4074048 | Process for the preparation of 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides A novel process for preparing 4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides is disclosed. The process involves the base catalyzed rearrangement of a saccharinacetamide of structure I to give II, ##STR1## wherein R1 is hydrogen ... | 02/14/1978 |
| 4071686 | Novel benzylidene amino-oxyalkyl carboxylic acids and carboxylic acid derivatives Certain nuclear substituted benzylidene amino oxyalkyl carboxylic acids esters, amides and salts thereof have been found to have a strong anti-inflammatory activity and a potent analgetic activity. In addition, some of the compounds have an activity again... | 01/31/1978 |
| 4064125 | Substituted amides having antiinflammatory activity Compounds having the formula ##STR1## wherein R1 is alkyl, cycloalkyl or aryl; R2 is acyl; R3 is alkylamino or dialkylamino; A1 is a saturated bond or an alkylene group having 1 to 4 carbon atoms; and A | 12/20/1977 |
| 4055595 | Substituted aryloxy-3,3,3-trifluoro-2-propionic acids, esters and salts thereof Derivatives of 2-hydroxy-3,3,3-trifluoro-2-(alkyl or trifluoromethyl)propionic acid bearing a phenyl or naphthyl group linked to the 2-hydroxy group either directly or via an intermediate methylene group. The compounds reduce the concentrations of cholest... | 10/25/1977 |
| 4053471 | 4-Thiazolidinone derivatives Compounds having the formula ##STR1## wherein R1 is alkyl, cycloalkyl or aryl; R2 is alkylamino, dialkylamino or a nitrogen containing heterocyclic group; A1 is a saturated bond or an alkylene group having 1 to 4 carb... | 10/11/1977 |
| 4053606 | Mercaptoalkylpyridine disulfides Mercaptoalkylpyridines carrying an ethenyl or ethynyl substituent are prepared from known pyridine compounds, principally pyridoxine, by known chemical procedures, and are useful in the treatment of rheumatoid arthritis and related inflammatory diseases.... | 10/11/1977 |
| 4052412 | Benzo cycloheptathiophene carboxylic acid derivatives This invention provides new compounds of formula I, ##STR1## wherein R1 is hydrogen, halogen of atomic number from 9 to 35 or lower alkyl, R2 is hydrogen or lower alkyl, each of R3 and R4 is hydrogen, or R3... | 10/04/1977 |
| 4049700 | Ibuprofen p-hydroxyphenylurea ester Ibuprofen p-hydroxyphenylurea ester having the formula II: ##STR1## was prepared from the free acid, ibuprofen [b1;2-(p-isobutylphenyl)propionic acid](I). The ester II above has the anti-inflammatory activity of the free acid, but in contradistinct... | 09/20/1977 |
| 4049824 | Cetyl myristoleate A method is described for immunizing against inflammatory rheumatoid arthritis in mammals and for immunizing against and relieving at least one of the symptoms of inflammatory rheumatoid arthritis in mammals.... | 09/20/1977 |
| 4049699 | Ibuprofen p-hydroxybenzaldehyde semicarbazone ester Ibuprofen p-hydroxybenzaldehyde semicarbazone ester having the formula II: ##STR1## was prepared from the free acid, ibuprofen [b1;2-(p-isobutylphenyl)propionic acid] (I). The ester II above has the anti-inflammatory activity of the free acid, but ... | 09/20/1977 |
| 4046897 | 5-Mercaptopyridoxine alkanesulfonates and methods of use and pharmaceutical compositions 5-Mercaptopyridoxine C1-4 alkane sulfonates, particularly the ethane-1,2-disulfonate, is a superior pharmaceutically acceptable form of the previously preferred 5-mercaptopyridoxine hydrochloride and hydrobromide.... | 09/06/1977 |
| 4035509 | Methods and compositions for the use of 2-carboxy-5-oxo-5H-dibenzo[a,d]cycloheptenes, salts and esters thereof 2-Substituted-5-oxo-5H-dibenzo[a,d]cycloheptenes represented by the following formula: ##STR1## where R' is hydrogen, alkyl having 1 to 12 carbon atoms, or ##STR2## where n is an integer from 2 to 4, inclusive, and R4 and R5 | 07/12/1977 |
| 4024174 | Tranes-delta 2-prostaglandins Trans-Ɗ2 -prostaglandin compounds are disclosed of the formula: ##STR1## wherein A represents a grouping of the formula: ##STR2## R1 represents an alkyl group containing from 1 to 10 carbon atoms, or an alkyl group contain... | 05/17/1977 |
| 4018764 | Ureylenebis methyl-phenylene-carbonyl-bis-dihydro-2-oxo-naphthoxazine disultonic acids Ureylenebis[methyl-phenylene carbonyl]-bis-[dihydro-2-oxo-naphth-oxazine-disulfonic acids] and salts thereof useful as complement inhibitors.... | 04/19/1977 |
| 4010275 | Treatment of osteoarthritis The treatment of Osteoarthritis by orally administering a pharmaceutical preparation containing a furanoside of the formula I ##STR1## wherein R1 is hydrogen or alkyl with up to 7 carbon atoms, and R3, R5 and R6 | 03/01/1977 |
| 4001270 | 9-Benzoyl-1,2,3,4-tetrahydrocarbazole 9-Benzoyl-3-hydroxymethyl-1,2,3,4-tetrahydrocarbazole and 9-benzoyl-3-(N-phenylcarbamoyloxymethyl)-1,2,3,4-tetrahydrocarbazole, having respectively antiinflammatory and antibacterial activities, and their preparation are described.... | 01/04/1977 |
| 3997559 | N-acetyl-L-hydroxy-proline zinc salt Derivatives of L-hydroxyproline and their use in the treatment of inflammation and wound healing.... | 12/14/1976 |
| 3985779 | M-phenoxyphenyl propionic acid derivatives and preparation thereof New meta-phenoxyphenyl propionic acid derivatives and pharmacologically acceptable salts thereof having excellent anti-inflammatory and analgesic activities with low toxicity are provided. The new compounds are adapted for therapeutical treatment of vario... | 10/12/1976 |
| 3976674 | Aluminum salts of substituted phenylalkanoic acids Novel Mono- and di-basic aluminum salts of 2-(3-phenoxyphenyl)-and 2-(3-phenylthiophenyl)alkanoic acids provide tasteless and practically water insoluble forms of said alkanoic acids, which have anti-inflammatory activity in mammals, for formulating pharm... | 08/24/1976 |
| 3974188 | Process for producing cholestane type steroids A process for producing cholestanyl phosphate or epicholestanyl phosphate or salts thereof in which the hydroxyl group at the three-position of cholestanol or epicholestanol is converted into the phosphoric ester by reaction with a phosphorylating agent i... | 08/10/1976 |
| 3973022 | Quinolineacetic acid compositions Compounds of the formula ##SPC1## Wherein Ar denotes an optionally substituted phenyl group or hetero-aromatic group with 5 or 6 ring members wherein the atom directly bonded to the quinoline ring is a carbon atom, R1 represents hydrogen, ... | 08/03/1976 |
| 3971797 | S,S'-bis(pyridylmethyl)-carbonodithioates S,S'-bis(pyridylmethyl)-carbonodithioates and derivatives thereof have utility in the treatment of rheumatoid arthritis. The compound useful in the method of treatment is prepared from known pyridine derivatives and, principally, from pyridoxine and relat... | 07/27/1976 |
| 3966942 | 3-Substituted-5-hydroxy(mercapto)alkylidene-rhodanine derivatives 3-Substituted-5-hydroxy(mercapto)alkylidene-rhodanine derivatives in which the 3-substituent is lower alkyl, cycloalkyl, alkenyl, phenyl, phenylalkyl, substituted phenyl or pyridylmethyl and having anti-arthritic activity are generally prepared from the a... | 06/29/1976 |
| 3962257 | 3-Phenacylpiperidines 3-Phenacylpiperidines, useful as depressants, stimulants, and anti-inflammatory agents, are obtained by preparing, from a 3-halomethylpiperidine, a 3-piperidylmethylmagnesium halide which is condensed with a benzonitrile.... | 06/08/1976 |
| 3962261 | 2,3,4,5-Tetra hydro-5-oxo-1-benzothiepi N-4-carboxamide 1,1-dioxides Compounds of the formula: ##SPC1## Are disclosed. In the above formula, R1 is aryl such as benzene or a heterocycle such as pyridine, isoxazole, or thiazole. The aryl or heterocyclic group R1 is substituted or unsubstituted. R2 | 06/08/1976 |
| 3962438 | Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones 1H-Pyrimido[5,4,3-kl]phenothiazine-1,3(2H)-diones are prepared from the corresponding 1-thione-3-one compounds by methylation followed by acid hydrolysis. The 1,3-dione products and 1-thione-3-one intermediates are useful as anti-arthritic agents.... | 06/08/1976 |
| 3956325 | 5-Heterocyclic-1,2,3,6-tetrahydro-4(5H) pyrimidinone The compounds of this invention are 5-heterocyclic-1,2,3,6-tetrahydro-4(5H)-pyrimidinethiones which have pharmacological activity, in particular gastric acid secretion inhibitory activity, and 5-heterocyclic-1,2,3,6-tetrahydro-4(5H)-pyrimidinones which ... | 05/11/1976 |
| 3946036 | 6,11-Dihydro-11-oxo-dibenzo[b,e]thiepine-2-acetic acids The present invention provides compounds of formula I, ##SPC1## wherein R1 is hydrogen, fluorine, chlorine, bromine, hydroxyl, lower alkyl, lower alkoxy, amino or lower acylamino, and R2 is hydrogen or lower alkyl, Useful as antiphlogisti... | 03/23/1976 |
| 3936467 | Hydroxyalkylenimino-phenyl-acetic acids New -(cyclic tert. aminophenyl)-aliphatic acids, e.g. those of the formula ##SPC1## R1 = h or alkyl R2 = h, alk(en)yl, cycloalk(en)- yl or cycloalk(en)yl-alkyl A = hydroxylated lower alkylene And functional derivatives thereof, are... | 02/03/1976 |
| 3933840 | Azole derivatives Azole derivatives of the formula ##SPC1## Wherein R1 is free or esterified carboxyl or other functionally modified carboxyl group, R2 and R3 each are aryl; A is Cn H2n in which n is an integer from 1 ... | 01/20/1976 |
| 3933789 | Extraction of sterolins from plant material A method of obtaining a sterolin-rich product useful in the treatment of geriatric complaints such as benign hypertrophy of the prostate, comprising pulping a plant product containing sterolin, boiling the pulp in water, filtering the material thus obtain... | 01/20/1976 |
| 3932463 | 11-Deoxy-13-dihydro-prostaglandin-9-ketals This disclosure describes novel 11-deoxy-13,14-dihydro-prostaglandin-9-ketals useful as bronchodilators and as gastric acid secretion inhibitors.... | 01/13/1976 |
| 3932498 | 3-Indenyl-γ-(ketobutyric)-acid compounds New substituted indene acids and non-toxic pharmaceutically acceptable amides, esters and salts derived therefrom. The substituted indene acids disclosed herein have anti-inflammatory, anti-pyretic and analgesic activity. Also included herein are methods ... | 01/13/1976 |
| 3931207 | Tetramic acid analogs of pulvinic acid Tetramic acid analogs of pulvinic acid having anti-arthritic activity are prepared by treatment of the corresponding tetramic acid lactones with an alkali metal lower alkoxide.... | 01/06/1976 |