Quotables
"One of the greatest labor saving inventions of today is tomorrow!"
Vincent T. Floss
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5288716 | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis A method for prevention of atherosclerosis or for treatment of hyperlipidaemia or atherosclerosis comprises administering one of more pyridoxine derivatives to a host in need thereof.... | 02/22/1994 |
| 5281421 | Gemfibrozil formulations Improved oral formulations are prepared by admixing gemfibrozil with from 1 to 4%, by weight, of a pharmaceutically acceptable surfactant having an HLB value of from about 10 to about 50.... | 01/25/1994 |
| 5278189 | Prevention and treatment of occlusive cardiovascular disease with ascorbate and substances that inhibit the binding of lipoprotein (A) A method is provided for prevention and treatment of cardiovascular disease, such as atherosclerosis, by administering therapeutically effective dosages of a drug comprised of ascorbate, lipoprotein(a) binding inhibitors, and antioxidants.... | 01/11/1994 |
| 5272174 | Hydroxy-ML-236B derivatives, their preparation and use Derivatives of ML-236B carboxylic acid, its salts and esters and corresponding lactone have a hydroxy group at the 3"-position and optionally also at the 6'-position. These derivatives may be prepared by the enzymatic hydroxylation of a corresponding ML-2... | 12/21/1993 |
| 5268367 | Composition and method for lowering blood level of LDL-cholesterol A cholesterol or body weight regulating material comprising an enzyme resistant starch is disclosed. A composition which contains said enzyme resistant starch is also disclosed. A food, food material, and beverage, containing said enzyme resistant starch ... | 12/07/1993 |
| 5268181 | Method of using niacin to control nocturnal cholesterol synthesis The invention provides a therapeutic method to treat hyperlipidemia by administering to a human patient a single daily dose of a prolonged release dosage form of niacin, so that nocturnal cholesterol synthesis is effectively suppressed.... | 12/07/1993 |
| 5260305 | Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination A pharmaceutical combination is provided which includes an inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is pravastatin and a pharmaceutical which reduces serum cholesterol and/or inhibits cholesterol biosynthesi... | 11/09/1993 |
| 5260272 | Polyanionic polyamino acid inhibitors of mineral deposition and their synthesis Polypeptides of the formula poly (X)m (Y)n, wherein X is selected from the group consisting of aspartate, glutamate, glutamine, asparagine, mixtures and block polymers thereof, Y is selected from the group consisting of phosphoserine, sulfoser... | 11/09/1993 |
| 5258181 | Compositions containing psyllium The present invention relates to compositions comprising psyllium fiber and peanut paste, and the use of these compositions as laxatives and/or for cholesterol reduction benefits. The compositions are a convenient, portable, highly palatable, and well tol... | 11/02/1993 |
| 5254585 | Use of peroxidized lipids for the preparation of a drug intended for the treatment of circulatory insufficiencies by local application The present invention relates to the use of peroxidized lipids, having a degree of peroxidation of between 50 and 200 milliequivalents per kilogram, preferably of between 50 and 150 milliequivalents per kilogram, for the preparation of a pharmaceutical co... | 10/19/1993 |
| 5254593 | Compositions containing biguanides and derivatives thereof as inhibitors of nonenzymatic cross-linking The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts... | 10/19/1993 |
| 5254549 | New BHT ether compounds and their use as hypolipidemic and antiatherosclerotic drugs Pharmaceutically-active BHT-omega pyridyl ethers of the formula selected from BHT-omega-pyridyl ether compounds of the formula: ##STR1## wherein m=1,3 for m=1, Σ=6-9 for m=3, Σ=5-11 Sum (Σ)=[m+n+1 (for oxygen)] wherein the bond between the two carbon a... | 10/19/1993 |
| 5248688 | Method and substrate composition for treating atherosclerosis A method and substrate composition for treating atherosclerosis are provided. The method involves parenterally administering the substrate composition as an aqueous solution to substantially lower plasma cholesterol and substantially reverse arterial plaq... | 09/28/1993 |
| 5246960 | Oxetanones Racemic compounds of the formula ##STR1## wherein R1, R2, R3, R4, R5 and n are as described herein, enantiomers and diastereomers thereof, and salts of these esters with weak acids, are described... | 09/21/1993 |
| 5240702 | Method of treating stroke In accordance with the present invention, a method is provided for treating stroke. More particularly, the present invention relates to a method for treating stroke comprising injecting a non-emulsion, homogeneous solution of certain ethylene oxide-propyl... | 08/31/1993 |
| 5234946 | Substituted alkylamine derivatives The substituted alkylamine derivatives represented by formula (I) ##STR1## wherein R1 represents (a) substituted or unsubstituted C2-6 alkenyl group, (b) substituted or unsubstituted C3-6 cycloalkenyl group, (c) subst... | 08/10/1993 |
| 5234954 | Treatment of hyperlipidemia with 15-keto-prostaglandin compounds A method for treatment of hyperlipemia which comprises administering, to a subject in need of such treatment, a 15-keto-prostaglandin compound in an amount, effective in decreasing lipid concentration in the blood.... | 08/10/1993 |
| 5234952 | Reduction of thrombogenicity with lipids of blackcurrant seed Lipids obtained from blackcurrant seed are used for reducing thrombogenicity of blood vessels in humans.... | 08/10/1993 |
| 5232698 | Psyllium drink mix compositions Psyllium husk-containing drink mix compositions comprising small particle size psyllium husk and edible, water soluble salts. The edible, water soluble salts are present at a level sufficient to reduce the gellation rate of the psyllium husk when disperse... | 08/03/1993 |
| 5231090 | Treatment for hypercholesterolemia The present invention relates to a method of modifying serum cholesterol levels in a mammal by topically administering to the skin of the mammal an effective amount of at least one phospholipid. Atherosclerosis, and related complications, can be treated, ... | 07/27/1993 |
| 5219888 | Use of retinoids for the treatment of coronary artery disease A method to increase plasma high density lipoprotein levels for the treatment and prevention of coronary artery disease by administering a therapeutic amount of a retinoid of the general formula: ##STR1##... | 06/15/1993 |
| 5217992 | Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. [The isolation of these tocotrienols from natural sources and their chemica... | 06/08/1993 |
| 5211947 | Method for lowering blood cholesterol levels with granulocyte-macrophage colony stimulating factor A method for lowering the blood cholesterol levels in mammals and humans by administering GM-CSF is disclosed.... | 05/18/1993 |
| 5210073 | Method for treating cancer therapy radiation damage or arteriosclerosis using human ADF A composition and method for the treatment of inflammation, rheumatism, autoimmune disease, ischemic damage of organs, drug toxicity and arteriosclerosis comprising human ADF is disclosed.... | 05/11/1993 |
| 5208258 | Antihypercholesterolemic compounds and synthesis thereof A method of preparing compactin and mevinolin, ketoacid, enone, and glutarate analogs thereof, and related compounds. The compounds are prepared in substantially enantiomerically pure form using a structurally convergent synthesis. Total syntheses of (+)-... | 05/04/1993 |
| 5202029 | Process for purification of HMG-CoA reductase inhibitors A process for the purification of an HMG-CoA reductase inhibitor employing preparative high performance liquid chromatography is described.... | 04/13/1993 |
| 5200424 | Use of 10-membered ring lactones as lipid regulators The compound of the formula ##STR1## in which, independently of one another, R1 and R4 are hydrogen or hydroxyl, R2 and R3 are hydroxyl, R5 is hydrogen, hydroxyl or an oxo group, and R2 and... | 04/06/1993 |
| 5198211 | Method of treating myocardial damage In accordance with the present invention, a method is provided for treating myocardial damage. More particularly, the present invention relates to a method for treating myocardial damage comprising injecting a non-emulsion, homogeneous solution of certain... | 03/30/1993 |
| 5192761 | 1,2,4-triazolidine-3,5-diones and 1,3,5-triazine-2,4(1-H,3H)-diones, pharmaceutical compositions The invention provides pharmaceutical compositions comprising hypolipidemically active derivatives of 1,2,4-triazolidine-3,5-diones, 1,3,5-triazabicyclo[3.1.0]hexane-2,4-diones, and 1,3,5-triazine-2,4(1H,3H)-diones in a pharmaceutically acceptable carrier... | 03/09/1993 |
| 5190923 | Peptide compounds containing a cyclic amide structure The invention relates to compounds of formula (I): ##STR1## in which: A represents, with the carbon and nitrogen atoms to which it is linked, cyclic amide as defined in the description, B represents, with the nitrogen and carbon atoms to which it is linke... | 03/02/1993 |
| 5186925 | Nitroglycerin pump spray The invention relates to a nitroglycerin pump spray containing 0.2 to 3.5% by wt. of nitroglycerin and up to 3% by wt. of customary additives such as flavoring agent or antioxidants and a liquid phase consisting of aliphatic C2 to C4... | 02/16/1993 |
| 5185349 | Substituted amide ACAT inhibitors lactone derivatives Novel lactone and lactam compounds which are useful to lower blood cholesterol levels in a patient, said compounds containing an arylcarboxamide or arylthiocarboxamide moiety.... | 02/09/1993 |
| 5179097 | Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids Novel choline salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids are described. Additionally, blends of choline salts with the above carboxylic acids are also described. The new salts and compositions offer new t... | 01/12/1993 |
| 5177104 | 6--hydroxy derivatives of mevinic acids Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof have been found to possess activity as cell-selective HMG-CoA reductase inhibitors, thus making them useful as antihypercholesterolemic agents. In the above formula, ... | 01/05/1993 |
| 5175156 | Chromic picolinate treatment The administration of chromic picolinate, preferably in the form of chromic tripicolinate, as a prophylactic or therapeutic agent for controlling various blood serum parameters. In particular, the administration is for controlling blood serum lipid levels... | 12/29/1992 |
| 5166171 | 6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiphenoxymethyl-4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, and in treating hypercholesterolemia 6-Phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiophenoxymethyl-4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, processes for the preparation of these compounds, their use as pharmaceut... | 11/24/1992 |
| 5145858 | Pyrrolo [1,2-a] imidazole and imidazo [1,2a] pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors Compounds comprising pyridyl and phenyl substituted pyrrolo[1,2-a]imidazole derivatives and pyridyl and phenyl substituted imidazo[1,2-a]pyridine derivatives, pharmaceutical compositions containing said compounds, and their use as 5-lipoxygenase pathway i... | 09/08/1992 |
| 5145678 | Method of reducing blood serum cholesterol The method of lowering human blood serum cholesterol consists of ingesting or administering to a patient orally once daily before any food intake a mixture of beet juice, lemon juice and bee honey. The mixture is in the proportions of about 1 part by volu... | 09/08/1992 |
| 5143937 | Benzenesulfonamides and a process for their preparation Compounds of the formula I ##STR1## where R1 to R5 have the meaning indicated, a process for their preparation and their use as medicaments are described. They are effective lipid-lowering agents with antioxidative properties fr... | 09/01/1992 |
| 5135920 | Angiostatic agents Dextran sulfate, ଲ-1,3-glucan sulfate, and the salts thereof are angiostatic and useful for treatment and prevention of various diseases caused by abnormally accelerated angiogenesis. Combination of such a compound with a steroidal or non-steroidal ... | 08/04/1992 |
