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| Number | Title | Issue Date |
| 7416743 | Polyherbal preparation for the prevention of atherosclerosis and hyperlipidemia A polyherbal preparation for the prevention of atherosclerosis and hyperlipidemia comprising a mixture of Commiphora mukul, Boswellia serrata, Semecarpus anacardium Strychnox nux vomica, Terminalia arjuna and Shankha Bhasma. ... | 08/26/2008 |
| 7361684 | Screening of compounds for treatment of atherosclerosis and heart attack Transgenic animals that do not express functional SR-BI and ApoE develop severe atherosclerosis, by age four weeks in transgenic mice. Moreover, these animals exhibit progressive heart dysfunction by as early as age four weeks, and die by age nine weeks. This animal... | 04/22/2008 |
| RE39734 | Nutritional or therapeutic compositions to increase bodily glutathione levels Nutritional or therapeutic compositions containing glutamic acid, cystine, glycine and a selenium precursor and methods for their utilization to increase glutathione synthesis and thereby enhance the immune system are described. ... | 07/17/2007 |
| 7179791 | Inhibiting GS-FDH to modulate NO bioactivity Patients needing NO donor therapy or inhibition of pathologically proliferating cells or increased NO bioactivity are treated with a therapeutically effective amount of an inhibitor of glutathione-dependent formaldehyde dehydrogenase. ... | 02/20/2007 |
| 7153877 | Method and composition for preventing or reducing the symptoms of insulin resistance syndrome A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bo... | 12/26/2006 |
| 7141558 | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring with an ethylidene or an ethyl group. These compounds have preferential activity on mobilizing calcium from bone and either high or normal intestinal calcium transport activity which allow... | 11/28/2006 |
| 7125547 | Poly(diallylamine)-based bile acid sequestrants The present invention relates to a method for removing bile acids from a patient and certain polymers of use in the method. The method comprises the step of administering to the patient a therapeutically effective amount of a polymer composition which includes a a p... | 10/24/2006 |
| 7119110 | Method and composition for preventing or reducing the symptoms of insulin resistance syndrome A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bo... | 10/10/2006 |
| 7112338 | Cationic liposome delivery of taxanes to angiogenic blood vessels Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cat... | 09/26/2006 |
| 7109187 | Estrogenic compounds as anti-mitotic agents The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosa... | 09/19/2006 |
| 7101570 | Liposome compositions and methods for the treatment of atherosclerosis The present invention provides compositions and methods for treating atherosclerosis. The compositions comprise unilamellar liposomes having an average diameter of 100-150 nanometers. Methods for treating atherosclerosis employing the compositions of the present inv... | 09/05/2006 |
| 7101838 | Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts The present invention provides for a method to prevent accelerated atherosclerosis in a subject predisposed thereto which comprises administering to the subject a polypeptide derived from soluble receptor for advanced glycation endproduct in an amount effective to p... | 09/05/2006 |
| 7087223 | Preventives and/or remedies for hyperphosphatemia Provided in a phosphate ion adsorbent containing a weakly basic anion exchange resin as an active ingredient which aims at providing preventives and/or remedies for hyperphosphatemia having a high selectivity for the adsorption of phosphate ion and showing an effect... | 08/08/2006 |
| 7084109 | FVIIa antagonists This invention provides novel compounds which prevent or block a FVIIa mediated or associated process or event such as the catalytic conversion of FX to FXa, FVII to FVIIa or FIX to FIXa. In particular aspects, the compounds of the invention bind Factor VIIa (FVIIa)... | 08/01/2006 |
| 7078396 | Method of treating disorder related to high cholesterol concentration A method of treating a disorder related to a high cholesterol concentration, comprising administering to a subject in need thereof a compound of formula (I): Also disclosed are methods, kits, combinations, and co... | 07/18/2006 |
| 7078411 | Phospholipid transfer protein (PLTP) and cholestoral metabolism A method for controlling cholesterol metabolism in a host, a screening assay for agents that can control cholesterol metabolism, and the agents that may be identified are practiced and determined in relation to the expression of PLTP in HepG2 cells and a clone from ... | 07/18/2006 |
| RE39150 | Composition for creating vascular occlusions A composition including 2-hexyl cyanoacrylate and goal is useful in treating arteriovenous malformations (AVMs) and other body lumens to be blocked. ... | 06/27/2006 |
| 7022722 | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis The subject invention provides pharmaceutical compounds useful in the treatment of Type II diabetes. These compounds are advantageous because they are readily metabolized by the metabolic drug detoxification systems. Particularly, thiazolidinedione analogs that have... | 04/04/2006 |
| 7011854 | Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof Several classes of in vivo carbon monoxide-releasing compounds are useful for the treatment and/or prevention of diseases, such as chronic inflammatory, e.g., rheumatoid arthritis, and of diseases with a strong inflammatory component, such as atherosclerosis, stroke... | 03/14/2006 |
| 7008645 | Method of inhibiting restenosis using bisphosphonates A method of inhibiting the activity or production of cytokines or growth factors associated with vascular restenosis, by administering to an individual an effective amount of an active ingredient comprising a bisphosphonate particle or a bisphosphonate particulate. ... | 03/07/2006 |
| 6989165 | Synergistic composition for treating hyperilipdemia The present invention relates to a synergistic pharmaceutical composition useful for the treatment of hyperlipidemia, said composition comprising extracts of plant Gentiana kurroo of concentration ranging between 2–5 wt. %, Murraya koenigii of concen... | 01/24/2006 |
| 6984400 | Method of treating restenosis using bisphosphonate nanoparticles A method of treating or preventing restenosis by administering to an individual an effective amount of an active ingredient comprising a bisphosphonate particle or a bisphosphonate particulate. The bisphosphonate may be encapsulated, embedded or adsorbed within the ... | 01/10/2006 |
| 6979679 | Composition and method for treatment and prevention of traumatic synovitis and damage to articular cartilage The invention provides compositions useful for the treatment and/or prevention of damage to diarthrodial (synovial) joints and, in particular, traumatic synovitis, inflammation of the synovial membrane, and damage to the articular cartilage of the joint. Specificall... | 12/27/2005 |
| 6977089 | Methods of using pomegranate extracts for causing regression in lesions due to arteriosclerosis in humans Methods of using pomegranate extracts of the present invention for treating patients with atherosclerosis, or increased intima-media thickness of an artery, are provided. The methods comprise the step of administering to the patient a composition comprising a therap... | 12/20/2005 |
| 6958359 | Vanadium compounds as anti-angiogenic agents Vanadium compounds for inhibiting angiogenesis useful for treating or preventing diabetic retinopathy, hemangiomas, cancers with abnormal blood vessel supply, restenosis following vascular injury, and the like. ... | 10/25/2005 |
| 6932989 | Therapeutic composition providing enhanced cardiac function A herbal therapeutic composition is provided which enhances cardiac function comprising hawthorn berry, turmeric root and cayenne pepper. Other herbal substituents which further enhance this novel composition are disclosed including motherwort, bilberry, fresh dande... | 08/23/2005 |
| 6911216 | Targeted delivery via biodegradable polymers Delivery of bioactive molecules such as nucleic acid molecules encoding a protein can be significantly enhanced by immobilization of the bioactive molecule in a polymeric material adjacent to the cells where delivery is desired, where the bioactive molecule is encap... | 06/28/2005 |
| 6890958 | Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or hyperlipidemia. Combinations disclosed include a nicotinic acid derivat... | 05/10/2005 |
| 6884784 | Diagnosis and management of infection caused by chlamydia The present invention provides a unique approach for the diagnosis and management of infections by Chlamydia species, particularly C. pneumoniae. The invention is based, in part, upon the discovery that a combination of agents directed toward the vario... | 04/26/2005 |
| 6878388 | Vanadium compounds for treating proliferative cell disorders Vanadium compounds useful to prevent and/or inhibit adhesion, migration, and invasion of proliferative cells into surrounding tissue. ... | 04/12/2005 |
| 6863904 | Compositions and methods for prophylactic and therapeutic supplementation of nutrition in subjects The present invention relates to compositions without added iron and methods for prophylactic nutritional supplementation and therapeutic nutritional supplementation. Specifically, the method involves administering to an individual a composition comprising carotenoi... | 03/08/2005 |
| 6855734 | Glycine betaine and its use Pharmaceutical uses of glycine betaine, such as for the treatment of thromboses not induced by hyperhomocystenemia or homocystinuria, of blood disorders, such as blood coagulation, thrombi formation. ... | 02/15/2005 |
| 6852706 | Methods and compositions for healing heart wounds Levels of thyroid hormone can be decreased in a mammal to increase healing of heart wounds. The increased wound healing includes rapid re-epithelialization and recovery of normal architecture and function relative to mammals who have not been treated according to th... | 02/08/2005 |
| 6841177 | Pharmacological activities of curcuma longa extracts New pharmacological activities of Curcuma Longa extracts as antiproliferative and photosensitivisation agents and their use in proliferative diseases such as psoriasis, as reducers of plasmatic fibrinogen and the Apolipoprotein B/Apolipoprotein A-I quotient, ... | 01/11/2005 |
| 6835401 | Method of treating diseases caused by over-production of free-radicals The invention relates to a method for improving the cell protection which comprises the administration of a combination of the extracts of the plants Vitis vinifera and Lycopersicon esculentum with the vitamins C, E, beta-carotene and optionally seleni... | 12/28/2004 |
| 6835846 | Aliphatic compounds, process for their preparation and their usage The present invention provides an aliphatic compound represented by the following formula (I) or pharmacologically acceptable salts thereof: where n denotes an integer of 1 to 11, and 1 denotes... | 12/28/2004 |
| 6818636 | B-ring estratrienes This invention provides 3β-hydroxy-5,7,9-estratriene-17-one and a pharmaceutically acceptable salt of its 3-sulfate ester, which is useful as an estrogen. ... | 11/16/2004 |
| 6780886 | Antioxidant containing vitamin E metabolite The present invention provides a method of preventing or treating a disease caused by oxidation in vivo by administering a pharmacologically effective amount of at least one compound selected from the group consisting of: (1) 2,5,7,8-tetramethyl-2-(β-carboxyethyl)-... | 08/24/2004 |
| 6773719 | Liposomal compositions, and methods of using liposomal compositions to treat dislipidemias The present invention provides a liposomal composition for treating dislipidemias in human subjects, a method of using a liposomal composition, and devices and modes of operation of the devices and of the compositions, and kits related thereto. The invention provide... | 08/10/2004 |
| 6703049 | Angiogenesis inhibitor The present invention relates to a novel angiogenesis inhibitor, more particularly, arsenolite (solid As4 O6) and composition containing the same. The arsenolite of the present invention inhibits endothelial cell proliferation and tu... | 03/09/2004 |
