Did You Know...
...that Kleenex tissue was originally designed to be a gas mask filter? It was developed at the beginning of World War I to replace cotton, which was then in short supply as a surgical dressing.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7425340 | Permeation enhancing compositions for anticholinergic agents A transdermal or topical composition including anticholinergic agents, such as oxybutynin, a urea-containing compound and a carrier system. A method is disclosed for treating a subject for urinary incontinence while reducing the incidences of peak concentrations of ... | 09/16/2008 |
| 7090866 | Opioid agonist in a fast dispersing dosage form This invention relates to a pharmaceutical composition for oral administration comprising a carrier and, as active ingredient, an opioid (μ receptor) agonist, such as fentanyl, or a salt thereof, characterized in that the composition is in the form of a fast-disper... | 08/15/2006 |
| 7041705 | Injectable aqueous dispersions of propofol Irritation upon injection of a formulation containing propofol is reduced or substantially eliminated by administering a stable, sterile, and antimicrobial aqueous dispersion comprising a water-insoluble microdroplet matrix of mean diameter from about 50 nm to about... | 05/09/2006 |
| 7030100 | Isoform specific inhibition for treatment of pain and reduction of anesthetic threshold Several lines of evidence have shown a role for the nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) signaling pathway in the development of spinal hyperalgesia. However, the roles of effectors for cGMP are not fully understood in the processing of pain in th... | 04/18/2006 |
| 7001759 | Compositions and methods for delivery of genetic material Methods of introducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a polynucleotide function enhancer and administering to the ... | 02/21/2006 |
| 6953590 | Tape material for transcutaneous absorption A preparation for transdermal absorption is disclosed which is suited for alleviating lasting pains caused by herpes zoster or postherpetic neuralgia and is practical and more improved in drug efficacy, safety and application characteristics. This tape preparation f... | 10/11/2005 |
| 6921541 | Formulations and methods for providing prolonged local anesthesia A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local an... | 07/26/2005 |
| 6894078 | Alcohol based topical anesthetic formulation and method A method for applying a topical anesthetic to an area of skin comprising the steps of a) incorporating an anesthetic in a lipophilic base into a volatile solvent, to form a homogeneous solution; b) applying the homogeneous solution into the area of skin to be treate... | 05/17/2005 |
| 6881756 | Method for treating skin disorders The present invention relates to a method for reducing inflammation in the skin and/or treating inflammatory skin disorders, pain, or pruritis by topically applying a composition comprising totarol or a pharmaceutically-acceptable ester thereof. ... | 04/19/2005 |
| 6872390 | Local anesthetic methods and kits Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. A... | 03/29/2005 |
| 6774131 | Remedies for endothelin-induced diseases A pharmaceutical composition for therapeutically treating prostate cancer, the pharmaceutical composition containing N-[6-methoxy-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyri midinyl]-2-phenylethenesulfoneamide or a pharmaceutically acceptable salt thereof as the e... | 08/10/2004 |
| 6764678 | Local anesthetic methods and kits Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. A... | 07/20/2004 |
| 6713527 | Anaesthetic bone cement The invention relates to surgical bone cement compositions and more particularly to bone cement compositions having aneasthetic properties, and to methods for producing analgesia. ... | 03/30/2004 |
| 6699908 | Methods for providing safe local anesthesia Methods and formulations for inducing substantially safer local anesthesia in a patient are provided. The methods comprise administering, to a patient in need thereof, a substrate containing a local anesthetic and an effective amount of a biocompatible, b... | 03/02/2004 |
| 6680071 | Opioid agonist in a fast dispersing dosage form This invention relates to a pharmaceutical composition for oral administration comprising a carrier and, as active ingredient, an opioid (μreceptor) agonist, such as fentanyl, or a salt thereof, characterized in that the composition is in the form of a f... | 01/20/2004 |
| 6638966 | Use of melatonin analogues for induction of general anesthesia Melatonin (N-acetyl-5-methoxytryptamine), or its biologically active analogues, are used to induce anesthesia.... | 10/28/2003 |
| 6635236 | Method for treating podotrochlosis A method for treating podotrochlosis (navicular disease/navicular syndrome) in the foot of a horse is disclosed. The method comprises identifying the specific area(s) of the horse's foot affected by navicular disease and applying at least one extracorpore... | 10/21/2003 |
| 6562855 | Anaesthetic formulation comprising an NMDA-antagoinst and an alpha-2 adrenergic agonist A pharmaceutical composition is described. The composition comprises a formulation. The formulation comprises an NMDA antagonist and an alpha-2 adrenergic agonist. In a preferred aspect, there is provided an improved anaesthetic comprising an NMDA antagon... | 05/13/2003 |
| 6552064 | Use of melatonin for induction of general anesthesia Melatonin (N-acetyl-5-methoxytryptamine), or its biologically active analogues, are used to induce anesthesia.... | 04/22/2003 |
| 6521259 | Formulations and methods for providing prolonged local anesthesia A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of t... | 02/18/2003 |
| 6509028 | Methods and compositions for treating pain of the mucous membrane Compositions useful for long-lasting pain relief from mucosal damage, such as mucosal inflamation, abrasions, ulcerations, lesions, trauma and incisions, without significant systemic absorption. The compositions of the invention are particularly suitable ... | 01/21/2003 |
| 6468982 | Genetic immunization Methods of prophylactic and therapeutic immunization of an individual against pathogen infection, diseases associated with hyperproliferative cells and autoimmune diseases are disclosed. The methods comprise the steps of administering to cells of an indiv... | 10/22/2002 |
| 6432401 | Local anesthetic methods and kits Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor an... | 08/13/2002 |
| 6426339 | Formulations and methods for providing prolonged local anesthesia The use of glucocorticosteroids in methods and formulations for prolonging and/or reactivating local anesthesia or local anesthesia previously induced by a local anesthetic agent, is disclosed.... | 07/30/2002 |
| 6413987 | Dermal anesthetic agents The present invention relates to new aminoindane piperidine compounds, the method of using aminoindane compounds as local anesthetics, said compounds having particularly valuable properties as dermal and topical anesthetics in mammals, including man, as w... | 07/02/2002 |
| 6361319 | Acid resistant film forming dental composition and method of use A method of decreasing the permeabilty of dentin by the application of an effective amount of oxalic acid potassium salt, dihydrate in an aqueous solution at a pH of about 2.0 to 4.0 to the dentin.... | 03/26/2002 |
| 6355705 | Anaesthetic bone cement A polymethacrylate or other bone cement composition having analgesic properties is described. Bone cements containing up to 5% by weight of a local anaesthetic agent, such as lidocaine, have been demonstrated to elute sufficient lidocaine to provide an an... | 03/12/2002 |
| 6350465 | Headache treatment and method A method of treating headaches by blocking the sphenopalatine ganglion comprises using a first device to anesthetize a front portion of the nasal cavity. A second device is used to anesthetize a rear portion of the nasal cavity. After these priming anesth... | 02/26/2002 |
| 6309625 | One-part dental compositions and methods for bleaching and desensitizing teeth Composition and methods that include potassium nitrate for whitening and/or reducing tooth sensitivity. The dental compositions may optionally include a dental bleaching agent, such as hydrogen peroxide or carbamide peroxide. The dental compositions may b... | 10/30/2001 |
| 6306370 | Compositions and methods for whitening and desensitizing teeth Composition and methods that include potassium nitrate for whitening and/or reducing tooth sensitivity. The dental compositions may optionally include a dental bleaching agent, such as hydrogen peroxide or carbamide peroxide. The dental compositions may b... | 10/23/2001 |
| 6297290 | Composition containing a nerve fiber reactivity modulating compound The present invention relates to a novel aqueous composition based on a compound modulating the reactivity of nerve fibers. It relates more particularly to a pharmaceutical composition for topical use on a human or animal body and intended to anesthetize ... | 10/02/2001 |
| 6251371 | Treatment of skin or mucosa inflammation by topical treatment with preparation containing dichlorobenzyl alcohol The present invention relates to use of dichlorobenzyl alcohol for preparing a preparation for topical treatment of inflammation and the preparation for this purpose. It is known to use dichlorobenzyl alcohol (2,4-DCBA) as an agent against bacteria and fu... | 06/26/2001 |
| 6214387 | Biodegradable polymer matrices for sustained delivery of local anesthetic agents Biodegradable controlled release microspheres for the prolonged administration of a local anesthetic agent, and a method for the manufacture thereof are disclosed. The microspheres are formed of a biodegradable polymer degrading significantly within a mon... | 04/10/2001 |
| 6143736 | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series Methods, compositions, and compounds for modulating the GABAA receptor-chloride ionophore complex to alleviate stress, anxiety, seizures, mood disorders, PMS and PND and to induce anesthesia.... | 11/07/2000 |
| 6106848 | Topically applicable O/W emulsions having high glycol content and at least one biologically active agent Stable, topically applicable oil-in-water bioaffecting emulsions having intermediate viscosity, characteristically ranging from 3 to 10 Pa.multidot.s, comprise (a) from 30% to 50% by weight of at least one pro-penetrating glycol, (b) at least one emulsify... | 08/22/2000 |
| 6103771 | Method of treating neuroma pain Methods of treating a host suffering from neuroma pain are provided. In the subject methods, a topical local anesthetic composition is applied to a keratinized skin site of the host proximal to the neuroma responsible for the neuroma pain. Preferably, the... | 08/15/2000 |
| 6075059 | Compositions for dental anesthesia Anesthetic compositions that achieve enhanced anesthesia of the peripheral nerves located in the mouth region of a subject or patient are provided. Such anesthetic compositions comprise water, a local anesthetic agent, and a sugar alcohol at a concentrati... | 06/13/2000 |
| 6054461 | Treatment of neuropathic pain A method of relieving neuropathic pain uses moxonidine and its physiologically compatible acid-addition salts for the treatment and/or prophylaxis of neuropathic pain. A composition comprising an effective amount of moxonidine, or a pharmaceutically accep... | 04/25/2000 |
| 6046187 | Formulations and methods for providing prolonged local anesthesia The use of glucocorticosteroids in methods and formulations for prolonging and/or reactivating local anesthesia or local anesthesia previously induced by a local anesthetic agent, is disclosed.... | 04/04/2000 |
| 6031007 | Pharmaceutical composition with anaesthetic effect The invention is directed to a novel pharmaceutical composition comprising one or more local anaesthetics in oil form, one or more surfactants, water and optionally a taste masking agent. The novel composition is advantageously used as a local anaesthetic... | 02/29/2000 |
