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| Number | Title | Issue Date |
| 7261907 | Compositions for the treatment of neurological disorders A non-stoichiometric clathrate of lipid and sulfur has been shown to effectively stabilize nerve cell membranes. As such, said compound has proven useful in a variety of neuropsychiatric disorders such as, addiction, depression, autism, Tourette's syndrome, and the ... | 08/28/2007 |
| 7087575 | Treating the effect of nicotine The invention provides methods and materials for treating the effects of nicotine. In particular, the invention provides methods that involve administering a neurotensin receptor (NTR) agonist to a mammal that has been exposed to nicotine. The NTR agonist typically ... | 08/08/2006 |
| 7074833 | Use of the (1S,2R) enantiomer of milnacipran for the preparation of a drug A method for treating or preventing a disorder or a condition by double inhibition of serotonin (5-HT) and noradrenaline (NA) reuptake in a subject in need thereof, while limiting the risks of cardiovascular disturbances and/or organ and/or tissue toxicity, comprisi... | 07/11/2006 |
| 7005452 | Use of the dextrogyral enantiomer of milnacipran for the preparation of a drug The present invention concerns the use of a mixture of enantiomers enriched in the dextrogyral enantiomer of milnacipran and/or of at least one of its metabolites, as well as their pharmaceutically-acceptable salts, for the preparation of a drug intended to prevent ... | 02/28/2006 |
| 6930122 | Use of central cannabinoid receptor antagonist for preparing medicines designed to facilitate smoking cessation The invention relates to the use of N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide for helping to quit tobacco consumption. ... | 08/16/2005 |
| 6828349 | Treatment of addiction and addiction-related behavior The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamma vinylGABA... | 12/07/2004 |
| 6749870 | Compositions and methods for the control of smoking A composition for the control of smoking which comprises: (a) a flavonoid in the form of an extract from Eupatorium cannibium or Eupatorium Fortunei, preferably euparin; (b) a cytochrome P450 inhibitor; (c) a sugar; (d) a source of phosphate; and, opti... | 06/15/2004 |
| 6660754 | Method for reducing or eliminating smoking This invention is an improved method for reducing or eliminating tobacco usage and the nicotine dependency associated with tobacco usage by gradually decreasing an individual's tobacco consumption over a time period while replacing nicotine from tobacco w... | 12/09/2003 |
| 6608064 | Pharmaceutical agents for the treatment of Parkinson's disease, ADHD and microadenomas The present invention is directed to the use of certain pyrido[1,2-a]-pyrazine derivatives, also described as bis-azabicyclic compounds and defined by the formula (I) herein, in the treatment of Parkinson's disease, attention deficit hyperactivity disorde... | 08/19/2003 |
| 6548510 | Pharmaceutical composition containing deoxypeganine for the treatment of nicotine dependence Desoxypeganine and its pharmaceutically acceptable acid addition salts are useful in treating nicotine dependence.... | 04/15/2003 |
| 6541520 | Treatment of addiction and addiction-related behavior The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamm... | 04/01/2003 |
| 6492369 | Therapeutic agents for drug dependence A method for preventing or treating drug dependence comprising administering to a human in need thereof a pharmaceutically effective amount of a 1,4-(diphenylalkyl)piperazine compound represented by the following formula [I] or a pharmaceutically acceptab... | 12/10/2002 |
| 6489357 | Tobacco cembranoids block the expression of the behavioral sensitization to nicotine and inhibit neuronal acetylcholine receptors The subject invention relates the use of cembranoids to inhibit nicotine addiction at the behavioral level. The subject host is sensitized to nicotine. Cembranoids are then administered to reduce such sensitization.... | 12/03/2002 |
| 6479509 | Method of promoting smoking cessation A method of training a smoker to cease smoking by administering tropane compounds is provided.... | 11/12/2002 |
| 6468987 | Nutritional product for a person having ulcerative colitis An enteral nutritional product for a person having ulcerative colitis contains in combination (a) an oil blend which contains eicosapentaenoic acid (20:5n3) and/or docosahexaenoic acid (22:6n3), and (b) a source of indigestible carbohydrate which is metab... | 10/22/2002 |
| 6358060 | Two-stage transmucosal medicine delivery system for symptom relief A two-stage medicine delivery system provides an initial dose of medicine and a second dose of medicine. The initial second doses are capable of achieving a rapid pharmacological effect and a prolonged pharmacological effect, respectively. The two-stage m... | 03/19/2002 |
| 6358527 | Fast-dissolving galanthamine hydrobromide tablet The present invention is concerned with a fast-dissolving tablet for oral administration comprising as an active ingredient a therapeutically effective amount of galanthamine hydrobromide (1:1) and a pharmaceutically acceptable carrier, characterized in t... | 03/19/2002 |
| 6268386 | Nicotine beverage A liquid composition including a Nicotine or alkaloid having the same direction of activity, content of between 0.0001% and 0.1% that can be consumed orally.... | 07/31/2001 |
| 6248760 | Tablet giving rapid release of nicotine for transmucosal administration A tablet for the transmucosal administration of nicotine. The nicotine is in one or more layers upon a non-nicotine containing matrix. The nicotine layers rapidly dissolve in the mouth. The nicotine is then rapidly absorbed by the intra-oral mucosal surfa... | 06/19/2001 |
| 6238689 | Intestinal absorption of nicotine to treat nicotine responsive conditions A delayed and sustained release composition of an additive and/or toxic agent such as nicotine is delivered systemically in therapeutic amounts while avoiding the peak plasma levels which gives rise to addiction and/or toxic side effects. The composition ... | 05/29/2001 |
| 6224897 | Methods to abate the use of tobacco by humans The present invention is directed to patient-controlled, flexible-dosing methods of treatment utilizing transdermal nicotine patch devices, optionally with other nicotine delivery systems, to abate the use of tobacco in humans.... | 05/01/2001 |
| 6218421 | Method of promoting smoking cessation A method for promoting smoking cessation, which method comprises administrating an effective, non-toxic amount of ropinirole or a pharmaceutically acceptable salt or solvate thereof to a human in need thereof. Said ropinirole is preferably administered or... | 04/17/2001 |
| 6211194 | Solution containing nicotine A nicotine method and solution which utilizes an acidic solution containing nicotine. The solution is for use to treat various medical conditions, such as to reduce the need of a user of smoking tobacco to smoke tobacco, to reduce attention deficit disord... | 04/03/2001 |
| 6204289 | Cembranoid inhibitors of nicotinic acetylcholine receptors The present invention relates to the use of cembranoids to inhibit nicotinic acetylcholine receptors.... | 03/20/2001 |
| 6197827 | Nicotine addiction treatment The present invention encompasses methods of treating patients for tobacco addiction and nicotine addiction, for palliating the effects of nicotine withdrawal, for providing or facilitating the effects of smoking cessation therapies and as long-term smoki... | 03/06/2001 |
| 6165497 | Subsaturated nicotine transdermal therapeutic system Rate controlled transdermal nicotine delivery systems are disclosed which utilize an in-line adhesive to maintain the systems on the skin. The initial equilibrated concentration of nicotine in the nicotine reservoir and the adhesive is below saturation, p... | 12/26/2000 |
| 6159963 | Method for treating substance abuse The invention provides a method for treating substance abuse comprising administering an effective amount of olanzapine or pharmaceutically acceptable salt thereof to a patient in need thereof.... | 12/12/2000 |
| 6153629 | Use of a combination of an anti-smoking composition and a dietary composition in smoking cessation A combination of a dietary composition and an anti-smoking composition which has the effect of increasing the number of people successfully completing a cure of smoking cessation and/or nicotine dependence. The dietary composition has a calorie content eq... | 11/28/2000 |
| 6083962 | Agonist-anatagonist combination to reduce the use of nicotine and other drugs A method of treating and reducing a drug dependency such as a nicotine dependency is provided. The method comprises initially administering to a subject a drug, such as nicotine or another agonist of the drug in an amount which would normally provide the ... | 07/04/2000 |
| 6057368 | Treatment of addiction and addiction-related behavior The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a primate suffering from substance addiction. The method includes administering to a primate an effective amount of a ... | 05/02/2000 |
| 5952314 | Nutritional product for a person having ulcerative colitis An enteral nutritional product for a person having ulcerative colitis contains in combination (a) an oil blend which contains eicosapentaenoic acid (20:5n3) and/or docosahexaenoic acid (22:6n3), and (b) a source of indigestible carbohydrate which is metab... | 09/14/1999 |
| 5935929 | Methods for treating interstitial lung disease by using interleukin-9 and its antagonists A method for the treatment and prevention of immune disorders and fibrosis associated disorders is disclosed. The method involves administering interleukin-9 in an effective amount to the subject. Among the conditions treatable are thyroiditis, autoimmune... | 08/10/1999 |
| 5935975 | Agonist-antagonist combination to reduce the use of nicotine and other drugs A method of treating and reducing a drug dependency such as a nicotine dependency is provided. The method comprises initially administering to a subject a drug, such as nicotine or an agonist of the drug in an amount which would normally provide the desir... | 08/10/1999 |
| 5925680 | Synthetic excitatory amino acids The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders.... | 07/20/1999 |
| 5919781 | Use of NK-1 receptor antogonists for treating substance use disorders The present invention provides a method for the treatment or prevention of substance use disorders using an orally active, long acting, CNS-penetrant NK-1 receptor antagonist and pharmaceutical compositions comprising such a NK-1 receptor antagonist.... | 07/06/1999 |
| 5888479 | Method for deterring smoking A method for reducing the desire of a person to smoke tobacco includes orally administering to the person an aqueous solution containing a polyvalent cation derived from a metal selected from the group consisting of palladium, copper, zinc, aluminum, tin,... | 03/30/1999 |
| 5869505 | Nicotine metabolites and nicotine dependence A therapeutic method is provided to alleviate the tobacco withdrawal syndrome, the symptoms of nicotine withdrawal or the management of human body weight in nicotine-experienced or nicotine-naive individuals, comprising of administering an amount of nicot... | 02/09/1999 |
| 5861422 | Agonist-antagonist combination to reduce the use of nicotine and other drugs A method of treating and reducing a drug dependency such as a nicotine dependency is provided. The method comprises initially administering to a subject a drug, such as nicotine or another agonist of the drug in an amount which would normally provide the ... | 01/19/1999 |
| 5852032 | Method of treating nicotine dependence A method of treating a subject afflicted with nicotine dependence with the opiate antagonist, nalmefene is described. The subjects will not gain significant amounts of weight as a result of smoking reduction or cessation.... | 12/22/1998 |
| 5830454 | Method for treating cell mediated autoimmune disorders using interleukin-9 A method for the treatment of cell mediated autoimmune disease is disclosed. The method involves administering interleukin-9 in an effective amount to the subject. Among the conditions treatable are thyroiditis and autoimmune diabetes.... | 11/03/1998 |
