|4634690||Substituted pyrimidinyl organophosphorus insecticides|
An organophosphorus compound having the structural formula ##STR1## where R is C1 -C4 alkyl; R1 is hydrogen or methyl; or R and R1 together are a diradical having the formula --SC(Y).dbd.Z--, where Y is hal...
|4581349||Certain benzodiimidazoles and their use as radiation sensitizers|
This invention relates to novel benzodiimidazole diols and diones and their ability to sensitize hypoxic cells to radiation, thus demonstrating utility for enhancing the treatment of solid tumors by radiation in a subject in need of such treatment....
|4579849||N-alkylguanine acyclonucleosides as antiviral agents|
Disclosed are compounds of the formula: ##STR1## and the pharmaceutically acceptable salts thereof wherein R1 and R2 are independently alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl or haloalkynyl, each having 1 to 19 carbon at...
|4565868||Process for preparing guanine derivatives|
1-Monophosphate esters, 1,3-bisphosphate esters and cyclic phosphate esters of 9-(1,3-dihydroxy-2-propoxymethyl)guanine are useful as antiviral agents....
Substituted 5H-pyrimido[5,4-b]indoles of Formula I ##STR1## wherein R2 is halogen; the oxadiazolyl group ##STR2## wherein R" is lower alkyl with up to 3 carbon atoms; C1-5 -alkyl, cycloalkyl, aralkyl, or aryl; ORI
|4536501||Substituted 4-phenoxy or 4-phenylthio prolines|
Compounds of the formula ##STR1## are disclosed. They possess angiotensin converting enzyme inhibition activity and diuretic activity and are therefore useful as antihypertensive agents....
|4500521||Pesticidal composition containing a synergistic combination of an oxazolo-pyridine thiophosphate derivative and cypermethrin|
A novel pesticidal composition containing the synergistically effective active-substance combination comprising the compound: S-[6-chloro-oxazolo[4,5-b]-pyridin-2(3H)-on-3-yl-methyl]-O,O-dimethyl-thio phosphate or the compound: (CH3 O)2
|4460590||Diglycidyl substituted heterocyclic compounds|
Diclycidyl substituted heterocyclic compounds of the formula: ##STR1## wherein X and Y can be the same or different and are either nitrogen or the radical C-R, where R is a hydrogen, or a hydrocarbon group, e.g., a straight or branched chain saturate...
|4425338||Alpha-heterocyclic carbinol phosphates|
Novel alpha-heterocyclic carbinol phosphates have been found to exhibit insecticidal and miticidal activity....
9-Hydroxyethoxymethyl (and related) derivatives of certain 6-, and 2,6-substituted purines have been discovered to have potent anti-viral activities. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulations containing the c...
Novel 2-amino substituted adenine compounds and their use as antiviral compounds are disclosed. In particular the compound 2-amino-9-(2-hydroxyethoxymethyl) adenine is particularly advantageous as an antiviral in that it has high oral absorption and that ...
|4288451||Combating arthropods with ferrocene-containing synergistic compositions|
An arthropodicidal composition containing, as active ingredients, an arthropodicidally effective amount of (1) at least one ferrocene derivative of the formula ##STR1## in which R and R1 each independently is hydrogen, an alkyl or alkenyl ...
9-(2-Hydroxyethoxymethyl) (and related) derivatives of certain 6-, and 2,6-substituted purines have been discovered to have potent anti-viral activities. Novel compounds and their pharamceutically acceptable salts, pharmaceutical formulations containing t...
|4201788||Process for alleviating proliferative skin diseases|
A process and pharmaceutical compositions for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals, topically and/or parenterally, and/or systemically a composition ...
|4199574||Methods and compositions for treating viral infections and guanine acyclic nucleosides|
9-Hydroxyethoxymethyl (and related) derivatives of certain 6-, and 2,6-substituted purines have been discovered to have potent anti-viral activities. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulation containing the co...
Aryl- and heterocyclic substituted phosphonothioureide compounds useful as anthelmintics....
|4152427||Combating pests with substituted pyrimidinone [(di)-thio]-phosphoric(phosphonic) acid esters and ester-amides|
Substituted pyrimidinone [(di)-thio]-phosphoric(phosphonic) acid esters and ester-amides of the formula ##STR1## IN WHICH R represents alkyl, R1 represents alkyl, phenyl, alkoxy, alkylthio or alkylamino, X represents oxygen or sulphur, Y repres...
|4144330||Insecticidal S-Triazolo-(1,5-a)-pyrimidin-2-yl-5,7-dimethyl phosphoric acid esters and amides|
S-Triazolo-(1,5-a)-pyrimidin-2-yl-5,7-dimethyl-phosphoric acid derivatives of the formula ##STR1## wherein X represents oxygen or sulphur, R1 represents C1 -C6 -alkyl, and R2 represents C1 -C6
|4076806||O-Alkyl-S-[3-oxo-1,2 ,4-triazolobenzopyrazin(2)yl-methyl]-(thiono)thiolphosphoric(phosphonic) acid esters|
O-Alkyl-S-[3-oxo-1,2,4-triazolobenzopyrazin(2)yl-methyl]-(thiono)thiolphosp horic(phosphonic) acid esters of the formula ##STR1## in which R is alkyl with 1 to 4 carbon atoms, R1 is alkyl or alkoxy with 1 to 4 carbon atoms, and X is oxygen or su...
|4070468||2-Amino-quinolin-4-one-3-phosphonic acid esters|
Anti-allergic 2-amino-quinolin-4-one-3-phosphonic acid esters are prepared by reacting an isatoic anhydride with the carbanion resulting from the treatment of an organo-methane phosphate with a proton abstracting agent....
|4067970||Pesticidal O-ethyl-S-n-propyl-O[pyrazolo(1,5-a)-pyrimidin-(2) yl]-thionothiolphosphoric acid esters|
O-Ethyl-S-n-propyl-O-[pyrazolo(1,5a)-pyrimidin(2)-yl]-thionothiolphosphoric acid esters of the formula ##STR1## in which R is hydrogen or halogen, R1 is alkyl with 1 to 5 carbon atoms or hydrogen, R2 is hydrogen, halogen or acetyl, a...
|4053602||Compositions for treating coccidiosis containing 5-deazariboflavin and its derivatives|
5-Deazariboflavin, its phosphate ester and non-toxic salts thereof and its novel bis(loweralkoxymethylene) derivatives have antiprotozoal and antiparasitic activity. They are particularly useful for controlling cecal and/or intestinal coccidiosis when adm...
Novel 1,2-dihydro-6-phenyl-1H,4H-imidazo[1,2-a][1,4]-benzodiazepin-1-ones of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, halogen, nitro and trifluoromethyl, R1 is selected from the group consisting ...
|4024252||2-(5-Ethyl-6-bromothiazolo[3,2-b]-5-triazolyl)thiophosphonate esters, compositions and method of use|
A compound of the formula ##STR1## WHEREIN R1 is alkyl having 1 to 3 carbon atoms; is useful as insecticide....
|4007268||Process for alleviating proliferative skin diseases|
A process and pharmaceutical composition for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans, or domesticated animals, topically, and/or parenterally, and/or systemically a composition...
|3970751||Certain thiazolotriazolyphosphonothioates used as insecticides|
A compound represented by the formula ##SPC1## Wherein R1 and R2 are lower alkyl having six or less carbon atoms, X is bromine is used to combat phylophogous insects....
Pesticidal compositions containing as active ingredients 2-(O,O-diethyl-thionophosphoryl)-5-methyl-6-carbethoxy-pyrazolo-(1,5a)-pyr imidine in admixture with (a) 2-methoxycarbonylamino-benzimidazole or (b) 1-(N-butylcarbamoyl)-2-methoxycarbonyl-amino-benzi...
|3957977||O-Alkyl-o-[3-methyl-1,2,4-triazolo-(2,3,b )-thiazol(6)-yl](thiono)-phosphoric (phosphonic) acid esters|
O-Alkyl-O-[3-methyl-1,2,4-triazolo-(2,3,b)-thiazol(6)-yl]-(thiono)-phosphor ic (phosphonic) acid esters of the formula ##SPC1## In which R is alkyl with 1 to 6 carbon atoms, R' is alkyl with 1 to 4 carbon atoms, alkoxy with 1 to 6 carbon atoms or phenyl, R...