U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Icon_funbox Bizarre Patents

Patent No. 5500234

Crispy Chip Sandwich and Process of Producing a Sandwich Product

A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.

Newsletter  PatentStorm News

Make the Most of Our Site

See this month's Top Inventors and Most Cited Patents.

Stay on top of the latest innovations by subscribing to an RSS feed.

Registered users: Manage your profile.

 

Class 514/809 - ENKEPHALIN OR ENDORPHIN OR DERIVATIVES


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter involving neurological peptides related to
No. of patents: 137
Last issue date: 08/14/2007


1        
NumberTitleIssue Date
7255882Enkephalinase inhibitor and GABA precursor loading as anti-anxiety compositions
Benzodiazepine withdrawal induced anxiety is treated by administration of an enkephalinase inhibitor, and a gamma-aminobutyric acid (“GABA”) precursor, or an endorphin or enkephalin releaser. These components promote restoration of normal neurotransmitter functi...
08/14/2007
6998387Human appetite control by glucagon-like peptide receptor binding compounds
A composition including a compound which binds to a receptor for glucagon-like peptide-1 and a pharmaceutical carrier. The amount of the compound present is effective to control appetite in a human. Also disclosed is a method for controlling appetite and for reducin...
02/14/2006
6867181Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing polymer and a free amino group-containing drug which are ionically bonded to each other. ...
03/15/2005
6221958Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50% by wei...
04/24/2001
6034175Salts of peptides with carboxy-terminated polyesters
This invention relates to novel salts composed of a cation derived from a peptide containing at least one basic group and an anion derived from a carboxy-terminated polyester, processes for the manufacture of such salts, and the use of such salts in the m...
03/07/2000
5889110Salts of peptides with carboxy-terminated polyesters
This invention relates to novel salts composed of a cation derived from a peptide containing at least one basic group and an anion derived from a carboxy-terminated polyester, processes for the manufacture of such salts, and the use of such salts in the m...
03/30/1999
5863985Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50% by wei...
01/26/1999
5672659Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
A composition including a polyester containing one or more free COOH groups ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein the polyester contains a member selected from the group of L-lactic ac...
09/30/1997
5169833Substituted cyclic pentapeptides
The present invention provides substituted cyclic pentapeptide compounds of general Formula I: ##STR1## and the pharmaceutically-acceptable slats, esters and amides thereof, which are useful for inducing analgesia in animals, pharmaceutical comp...
12/08/1992
5017689Dynorphin analogs specific for kappa opioid receptors
Cyclic disulfide and linear dynorphin Dyn A1-11 and dynorphin Dyn A1-13 analogs which are highly specific for .kappa. opioid receptors. These analogs are useful in pharmaceutical compositions and for the analysis of opioid receptor/l...
05/21/1991
4829056Buccal tablet comprising etorphine or a salt thereof
Pharmaceutical compositions in the form of a buccal tablet comprising etorphine or a salt thereof, at least one monosaccharide, disaccharide or a mixture thereof, and a mixture of xanthan gum and locust bean gum in a weight ratio 3:1 to 1:1, wherein the t...
05/09/1989
4757049Process for using endogenous enkephalins and endorphins to stimulate the immune system of patients with aids
A process for the therapeutic treatment of AIDS (acquired immune deficiency syndrome) involving stimulation and promotion of the natural immune system (both T cell and NK cell activity) resisting and inhibiting tumorous growth (cancer) as well as resistin...
07/12/1988
4707468Polypeptide
A novel polypeptide is defined by the below shown formula and is useful as an analgesic. ##STR1## wherein R1 and R2 may be the same or different and each represents a hydrogen atom or a lower alkyl or lower alkenyl group, A ...
11/17/1987
4684624Method of treating cerebral ischemia
A method of treatment for patients suffering from cerebral ischemia is provided by administering an opioid peptide. Particulary preferred is the administration of dynorphin, or dynorphin-related peptides, in the acid or amidated form. Practice of the inve...
08/04/1987
4670419Pharmaceutical composition and its rectal use
A pharmaceutical composition containing a hydrophilic drug which is poorly absorbable through the gastrointestinal tract, and cyclodextrin, increases the absorbability of the drug into the mammalian body when administered by a non-oral or non-injection ro...
06/02/1987
4657892Pharmacologically active peptides
Pharmacologically active peptides of the following formulas are described: in which L--Tyr is the N-terminal amino acid residue L-tyrosine, X any amino acid residue of the D-form, L--Phe is the amino acid L-phenylalanine, A and B are any desired amino acid res...
04/14/1987
4631270Therapeutically useful pseudopeptides, compositions containing the same and methods of preparation and use
Therapeutically useful pseudopeptides characterized by the replacement of at least one peptide group, both in a naturally occurring peptide or protein by a thiomethylene group are useful in the treatment of various metabolic malfunctions....
12/23/1986
4603121Enkephalin analogs
The invention relates to novel enkephalin analogs of the formula: ##STR1## which are useful as analgesic agents....
07/29/1986
4599325Substituted tyrosyl alanine dipeptide amides
The invention relates to novel substituted tyrosyl alanine dipeptide amides of the formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof wherein R1 represents straight or branched lower alkyl having 1 to 4 carbo...
07/08/1986
4579841Dipeptide derivatives having opiate activity
A class of dipeptide derivatives having opiate activity having the formula wherein X is a D- or L-amino acid radical and Y is an amide or substituted amide are disclosed....
04/01/1986
4540682Pharmaceutical peptides, preparation, use and intermediates
Novel peptides of formula (I) ##STR1## wherein R1 is hydrogen, alkyl of 1 or 2 carbon atoms or an amidino group, R2 is alkyl of 1 or 2 carbon atoms, R3 is hydrogen or carbamyl, X2 is a D-radical having the struc...
09/10/1985
4537878Process for using endogenous enkephalins and endorphins to stimulate the immune system
A process of stimulating and promoting the natural immune system (T cells and NK cells) resisting and inhibiting the growth of tumorous cells as well as resisting infections (virus bacteria, and fungi) is disclosed. Endogenous endorphins are disclosed as ...
08/27/1985
4533655Analgesic dipeptide amides and method of use and compositions thereof
A genus of dipeptide amides including as the preferred subgenus the dipeptide amides having the structural formula R1 TyrR2 D-AlaNHR4 wherein R1 and R2 are each hydrogen or alkyl provided that at leas...
08/06/1985
4533657Analgesic dipeptide amides and method of use and composition thereof
A genus of dipeptide amides including as the preferred subgenus the dipeptide amides having the structural formula HTyrD-AlaNR2 R3 wherein R2 is phenylalkyl or substituted-phenylalkyl and R3 is hydrogen, alkyl, ...
08/06/1985
4518711Conformationally constrained cyclic enkephalin analogs with delta receptor specificity
Novel compounds which are capable of binding with enhanced specificity to the delta receptor are disclosed. The compounds are a series of cyclic, conformationally constrained analogs of enkephalins which display exceptional delta receptor specificity. The...
05/21/1985
4496540Therapeutic compounds
In one aspect, compounds capable of inhibiting an endopeptidase responsible for a degradation pathway of enkephalin and having the general formula wherein A is one of the aromatic group-containing amino acid residues L-tryptophyl, D-tryptophyl, L-tyrosyl, D-ty...
01/29/1985
4495178Enkephalin analogs
The invention relates to novel enkephalin analogs of the formula: ##STR1## which are useful as analgesic agents....
01/22/1985
4438104Endorphins having placental or pancreatic origin
An endorphin peptide is described that has a molecular weight by amino acid analysis of about 14,000 daltons, an infrared spectrum substantially as shown in FIG. 5, and an amino acid analysis substantially as follows: The peptide is immunoreactive against �...
03/20/1984
4430327Method for treating pregnant females for pain and anxiety
A method is described for preventing or minimizing the effects of a drug on an embryo or a fetus by placental transport while alleviating pain and anxiety of the pregnant female by administering a pharmaceutically effective amount of a compound of the for...
02/07/1984
4421744Aminoacyl derivatives
Peptide and pseudopeptide derivatives of the formula: ##STR1## wherein R1 and R2 stand for defined hydrocarbyl or halo-hydrocarbyl substituents, for example alk-2-enyl radicals; .dbd.N--A-- stands for a defined amino acid residu...
12/20/1983
4407794Peptides and therapeutic applications thereof
This invention relates to peptide derivatives of the formula: in which: A is a D.Ala, AzaGly, Aib, D.Ser., D.Thr, D.Cys, homo Serine, ଲPhe Ser, ଲOH Leu, 4OH Ile, ଱,ଲ,γ OHNor Val or OH Val residue in which the side-chain OH or SH groups...
10/04/1983
4405607Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
Pentapeptides of formula I, ##STR1## wherein Z1 =H, CH3 or amidino; R1 =H or alkyl and R2 =H or R1 +R2 =--CH2 --CH2 --; R3 =m- or p--OH or -alkoxy; B=r...
09/20/1983
4380535Enkephalin degrading enzyme inhibitors
Compounds which inhibit the brain enzyme degradation of enkephalins and which exhibit their own analgesic effect, having the formula ##STR1## wherein R1 is hydrogen or lower alkyl; X is hydrogen, hydroxy, halo, nitro, amino or lower alkoxy...
04/19/1983
4371463Enzyme-resistant opiate pentapeptides
Pentapeptides having the formula wherein A is a D-amino acid residue, Sar or L-Pro, B is L-Met of L-Leu, and R is NH2 or OH. These pentapeptides are synthetic analogues of the naturally-occurring Met-and Leu-enkephalins and possess opiate activity ...
02/01/1983
4363800Biologically active amides
Peptides, acid addition salts, salts, and pharmaceutical compositions thereof, and their use as morphine agonists, and especially Tyr.D.Met.Gly.Phe (4NO2).ProNH2 and Tyr.D-Met(O). Gly. Phe(4NO2). ProNH2 as anti-...
12/14/1982
4362717Biologically active amides
Peptides, acid addition salts, salts, and pharmaceutical compositions thereof, and their use as morphine agonists, and especially Tyr.D.Met. Gly.Phe(4NO2).ProNH2 and Tyr.D-Met(O).Gly.Phe(4NO2).ProNH2 as anti-dia...
12/07/1982
4358440Polypeptide and its production and use
Novel polypeptide of the formula: H-Tyr-Gly-Gly-Phe-Met-Lys-Pro-Tyr-Thr-Lys-Gln-Ser-His-Lys-Pro-Leu-Ile-Thr-L eu-Leu-Lys-His-Ile-Thr-Leu-Lys-Asn-Glu-Gln-OH is useful as an analgesic agent. Methods of its preparation are also disclosed....
11/09/1982
4351763Pharmacologically active peptides
Compounds of the formula ##STR1## and pharmaceutically acceptable non-toxic acid addition salts thereof, in which L and D define the chirality; R1 is hydrogen or C1 -C3 primary alkyl; R2 is C1 -C...
09/28/1982
4350627Biologically active peptides
There is disclosed biologically active peptides of the formula ##STR1## where X is a hydrogen atom, an N-terminus protecting group (any of an acyl-type protecting group, an aromatic urethane-type protecting group, an alkyl-type protecting group, or a...
09/21/1982
4346083Biologically active amides
Peptides, acid addition salts, salts, and pharmaceutical compositions thereof, and their use as morphine agonists, and especially Tyr.D.Met.Gly.Phe(4NO2).ProNH2 and Tyr.D-Met(O).Gly.Phe(4NO2).ProNH2 as anti-diar...
08/24/1982
1        
 
Sign InRegister
Username  
Password   
forgot password?