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| Number | Title | Issue Date |
| 8080586 | Self-emulsifying preparations The invention relates to new self-emulsifying preparations containing (a) 7 to 20% by weight stearyl oligoglycoside, (b) 7 to 20% by weight cetyl oligoglycoside, (c) 0.1 to 3% by weight myristyl oligoglycoside, (d)... | 12/20/2011 |
| 7381422 | Method for producing sterile polynucleotide based medicaments The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are suitable for use in polynucleotide based medicaments. A suitable meth... | 06/03/2008 |
| 7332528 | DRI nasal sprays There are provided safe, tasteless, odorless, non-aqueous liquid spray compositions formulated for administration to the nasal cavity consisting essentially of pharmacologically acceptable non aqueous liquid carrier in which said bioactive material is directly insol... | 02/19/2008 |
| 7314638 | Preparing method for controlled released type tablet tamsulosin HCL and the tablet thereof The present invention relates to a simple and effective method for preparing a tamsulosin HCl sustained-release tablet and a tamsulosin HCl sustained-release tablet produced thereby. The method comprises the steps of: dissolving tamsulosin HCl as an active ingredien... | 01/01/2008 |
| 7309696 | Compositions and methods for targeting cancer cells The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions o... | 12/18/2007 |
| 7294619 | Lipid analogs for inhibiting the activity of hepatitis B antigen The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294621 | Lipid analogs for combating tumors The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294620 | Lipid analogs for inhibiting HIV-1 activity The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7285283 | Paper substrate impregnated with an emulsion having a polyol, poly-12-hydroxystearate emulsifier, an oil component and water A paper substrate impregnated with an emulsion containing: (a) a polyol poly-12-hydroxystearate; (b) an oil component selected from the group consisting of a dialkyl ether, a dialkyl carbonate, a glyceride, a hydrocarbon, a silicone oil, and mixtures thereof; (c) up... | 10/23/2007 |
| 7261907 | Compositions for the treatment of neurological disorders A non-stoichiometric clathrate of lipid and sulfur has been shown to effectively stabilize nerve cell membranes. As such, said compound has proven useful in a variety of neuropsychiatric disorders such as, addiction, depression, autism, Tourette's syndrome, and the ... | 08/28/2007 |
| 7252979 | Production of DHA in microalgae in low pH medium Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsa... | 08/07/2007 |
| 7189413 | Drug delivery of proteins from polymeric blends Degradable blend of polycaprolactone and crystallization modifier especially suitable for use in the controlled release of biologically active proteins ... | 03/13/2007 |
| 7163811 | Production of high levels of DHA in microalgae using modified amounts of chloride and potassium Methods for production of highly unsaturated fatty acids by marine microorganisms, including the heterotrophic marine dinoflagellate Crypthecodinium, using low levels of chloride ion are disclosed. Specifically, methods of increasing production of highly unsa... | 01/16/2007 |
| 7141557 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.... | 11/28/2006 |
| 7138394 | Vehicle for topical delivery of anti-inflammatory compounds A vehicle for topical delivery which contains a liquid eutectic mixture of hydrophobic compounds. ... | 11/21/2006 |
| 7135584 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.... | 11/14/2006 |
| 7129227 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpesviruses, is disclosed. The method comprises administering to a subject in need of such treatment an infection-combating amount of a phospholipid or phospholipid derivative. | 10/31/2006 |
| 7122553 | Liposomal formulation of irinotecan The present invention is for novel compositions and methods for treating cancer, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include liposome entrapped irinotecan in which the li... | 10/17/2006 |
| 7115667 | Ophthalmic fluid An ophthalmic fluid containing at least one triglyceride, diglyceride, or monoglyceride which is chemically similar or compatible with compounds found naturally in the lipid layer of the tear film of an ocular substrate. Preferably the glycerides are derived from a ... | 10/03/2006 |
| 7078054 | Soft gelatin capsule manufacture Soft gelatin capsules having a capsule shell comprising gelatin, plasticizers and, if desired or required, further auxiliary agents, and a capsule filling containing a solvent including a migrateable solvent such as 1,2-propyleneglycol as a solvent in the capsule fi... | 07/18/2006 |
| 7063855 | Composition for feeding prey organisms in aquaculture A composition is for feeding aquacultural prey organisms such as Artemia and rotifiers, comprising a lipid component comprising at least 25 wt % of phospholipids and providing a DHA content of at least 30 wt %. The lipid component is preferably derived from m... | 06/20/2006 |
| 7026469 | Compositions and methods of double-targeting virus infections and cancer cells The invention includes compositions and methods useful for treatment of a virus infection in a mammal by double-targeting the virus (i.e. targeting the virus at more than one stage of the virus life cycle) and thereby inhibiting virus replication. The compositions o... | 04/11/2006 |
| 7001621 | Blends of ursolic acid/oleanolic acid Blends comprising a glyceride and ursolic acid and oleanolic acid in weight ratios of 1:99 to 99:1 that contain less than 20 wt % of natural apolar components and/or low molecular weight components, normally present in natural extract for ursolic acid and oleanolic ... | 02/21/2006 |
| 6974593 | Insoluble drug delivery Particles of water insoluble biologically active compounds, particularly water-insoluble drugs, with an average size of 100 nm to about 300 nm, are prepared by dissolving the compound in a solution then spraying the solution into compressed gaz, liquid or supercriti... | 12/13/2005 |
| 6959663 | Rearing of aquatic species with DHA-rich prey organisms A method of rearing aquatic species is provided, comprising feeding the aquatic species during at least part of the larval and/or post-larval state with prey organisms, such as Artemia or rotifers, having in their total lipid content a DHA content of at least... | 11/01/2005 |
| 6936187 | Functionalized cubic liquid crystalline phase materials and methods for their preparation and use Functionalized cubic gel precursors, functionalized cubic liquid crystalline gels, dispersions of functionalized cubic gel particles and functionalized cubic gel particles are disclosed. Methods for preparing and using the precursors, gels, dispersions, and particle... | 08/30/2005 |
| 6932976 | Enzyme blocking skin protectant cream The present inventions relate to novel skin protectant creams and the use of such creams to cleanse, treat, and protect skin. The skin protectant creams can be topically applied to protect skin from irritants, to block the action of irritants such as enzymes, and to... | 08/23/2005 |
| 6861068 | Pharmaceutical compositions using semi-solid delivery vehicle A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is su... | 03/01/2005 |
| 6818224 | Use of gellable pharmaceutical compositions in periodontology A method is described for preparing a fluid pharmaceutical composition which allows the controlled release of at least one active substance. The method involves mixing a therapeutically effective amount of at least one active substance, from 3 to 55% by weight of ph... | 11/16/2004 |
| 6790458 | Pharmaceutical compositions using semi-solid delivery vehicle A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is su... | 09/14/2004 |
| 6761903 | Clear oil-containing pharmaceutical compositions containing a therapeutic agent The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present invention include a carrier, where the carrier is formed from a combination... | 07/13/2004 |
| 6753011 | Combined diffusion/osmotic pumping drug delivery system Delivery devices capable of delivering one or more active substances by diffusion through plural micropores in the membrane (4) or by osmotic pumping through one or more preformed passageways (5) in the membrane are provided. The device (1) has ... | 06/22/2004 |
| 6730329 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and water. Anoth... | 05/04/2004 |
| 6706263 | Composition for alleviating symptoms of uremia in patients Microencapsulated and/or enteric coated compositions containing a mixture of sorbents with specific adsorption affinities for uremic toxins including ammonia, urea, creatinine, phenols, indoles, and middle molecular weight molecules and a bacterial source which meta... | 03/16/2004 |
| 6706281 | Melt-extrusion multiparticulates A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an optional water-insoluble binder is disclosed. The particles have a length ... | 03/16/2004 |
| 6692775 | Bactericidal gel and method for treating burns and dermal lesions A gel formulation is combined with a bactericidal concentrate which is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a sp... | 02/17/2004 |
| 6692767 | Solid solution beadlet Disclosed is a beadlet comprising (i) a hydrophobic long chain fatty acid or ester material; (ii) a surfactant; and (iii) a therapeutic agent which in admixture form a solid solution at room temperature. The hydrophobic material preferably has a melting p... | 02/17/2004 |
| 6677327 | Phytosterol and phytostanol compositions The present invention relates to an edible phytosterol or phytostanol composition useful in the food industry and to methods of preparing such an edible composition. The edible composition comprises a phytosterol or phytostanol, an isolated water soluble ... | 01/13/2004 |
| 6673360 | Technique for emulsifying highly saturated hydroisomerized fluids A preferred emulsifier blend includes ethoxylated alcohols containing hydrocarbons of C10-C16 and preferably having on average at least 2.8 ethoxy and/or alcohol groups per chain and a glycerol mono- and/or dioleates, preferably in a ratio of from 9:1 to ... | 01/06/2004 |
| 6667043 | Technical di- and triglyceride mixtures A process for making technical di/triglyceride mixtures involving: (a) providing a vegetable oil; and (b) partially transesterifying the vegetable oil by reacting it with a component selected from the group consisting of a mixture of glycerol and a fatty ... | 12/23/2003 |
