Quotables
"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 4868157 | Dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives as host resistance enhancers in AIDS-immunocompromised hosts and methods of use Disclosed are specific dipeptidyl 2-amino-1,2-dideoxy-D-glucoses which, either alone, or in combintion with an anti-AIDS drug, e.g. azidothymidine, protect an immunocompromised human host, resulting from an AIDS-related virus, against opportunistic, bacte... | 09/19/1989 |
| 4866040 | Aminocarnitine directed pharmaceutical agents Carnitine, aminocarnitine and cysteic acid serve as carriers to bring pharmaceutically active compounds to desired sites in the body, e.g. skeletal muscle or the heart. The pharmaceutically active compound can be a protease inhibitor, a cardioactive drug ... | 09/12/1989 |
| 4866044 | Solubilized composition of poorly-soluble pharmaceutical product 3-(n-Octadecylcarbamoyloxy)-2-methoxypropyl 2-thiazolioethyl phosphate solubilized with use of a salt of salicyclic acid or/and a salt of a bile acid can be administered by stable injection without causing precipitation. A composition containing a reducin... | 09/12/1989 |
| 4866035 | Dipeptidyl saccharides as host resistance enhancers in AIDS-immuno-compromised hosts and methods of use Disclosed are specific dipeptidyl saccharide derivatives which alone, or in combination with an anti-AIDS drug, e.g. azidothymidine, provide protection against opportunistic infection in human individuals whose resistance to infection has been specificall... | 09/12/1989 |
| 4866036 | Dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose compositions and methods of use in aids-immunocompromised human hosts Disclosed are specific dipeptidyl 5-0, 6-0-Acyl-2-amino-2-deoxy-D-glucofuranoses, which, either alone, or in combination with an anti-AIDS drug, e.g. azidothymidine, provide protection in human individuals whose resistance to infection has been speci... | 09/12/1989 |
| 4857514 | Virus inactivation A virus having a lipid-containing capsid, such as AIDS virus, is inactivated by contacting the virus with an inactivating amount of phosphatidyl choline. Such a virus can be inactivated in fluids such as virus-contaminated body fluids or derivatives, e.g.... | 08/15/1989 |
| 4857319 | Method for preserving liposomes A method for preserving liposomes includes freeze-drying liposomes most preferably having an average size of about 50 nm to 100 nm with a disaccharide preserving agent being present both internally (with the encapsulated liposomal contents) and externally... | 08/15/1989 |
| 4847067 | Mold and dust inhibiting product and method A mold and dust inhibiting composition which has particular utility in connection with the storage and handling of animal feeds, grains, and hay, and also in connection with the use of animal litter such as poultry litter, as well as having general utilit... | 07/11/1989 |
| 4839389 | Polyprenyl alcohol-containing injections Polyprenyl alcohol-containing injections comprising polyprenyl alcohols shown by the formula: ##STR1## wherein n is an integer of 5 to 7, and lecithin as essential ingredients. The subject injections can enhance utilization of the polyprenyl alcohols... | 06/13/1989 |
| 4828837 | Non-crystalline minoxidil composition, its production and application An aqueous, noncrystalline minoxidil composition for topical use. The composition contains minoxidil complexed with an amphipathic compound having a pK less than about 5 and containing a single lipophilic chain moiety and a sulfate, sulfonate, phosphate a... | 05/09/1989 |
| 4826821 | Lung surfactant compositions An improved synthetic lung surfactant consists essentially of dipalmitoyl phosphatidyl choline, a C-14 to C-18 fatty alcohol (preferably hexadecanol), and a non-toxic nonionic surface active agent (preferably tyloxapol). The surfactant is prepared in a po... | 05/02/1989 |
| 4814161 | Drug-containing chlorofluorocarbon aerosol propellent formulations Complete dissolution of a wide range of drugs in chlorofluorocarbon aerosol propellents is achieved by the presence of glycerol phosphatides, preferably phosphatidylcholine.... | 03/21/1989 |
| 4812314 | Lipid replacement therapy A method of treating a relatively aged animal to reverse age-related changes in the lipid composition of organ and tissue cells, such as heart muscle cells, and the ability of the animal to withstand respiratory stress. A suspension of small unilamellar v... | 03/14/1989 |
| 4783450 | Use of commercial lecithin as skin penetration enhancer A method of enhancing penetration of a drug through the skin or other biological membranes using lecithin is herein described along with pharmaceutical compositions containing effective amounts of lecithin as a penetration enhancer.... | 11/08/1988 |
| 4780455 | Lipophilic complexes of pharmacologically active organic compounds The present invention provides a composition with the structure wherein m and n are each integers, and m and n are different or the same; L is an ampholytic lipid or polymer, or a nonampholytic lipid with hydrophobic properties; E is a nonlipophilic ionic inor... | 10/25/1988 |
| 4780456 | Pharmaceutical or dietetic composition having a high antiarteriosclerotic activity A pharmaceutical or dietetic composition for the prevention and treatment of vascular, arteriosclerotic and thrombotic pathologies, comprised of lecithin and oils having a high content of eicosapentaenoic (C 20:5, n-3) and/or docosahexaenoic (C 22:6, n-3)... | 10/25/1988 |
| 4771039 | Botulinus toxin neutralizer A botulinus toxin neutralizer comprising heat-treated fat globule membranes of animal milk or gangliosides isolated from fat globule membranes of animal milk. The neutralizer of the former nature is prepared from a material containing fat globules of anim... | 09/13/1988 |
| 4770878 | Mold and dust inhibiting product and method A mold and dust inhibiting composition which has particular utility in connection with the use of animal litter such as poultry litter, as well as having general utility for controlling both mold and dust. The composition of the invention is an aqueous so... | 09/13/1988 |
| 4766111 | Lipids with plasmin inhibitory properties Plasmin inhibitory substances have been found in mammalian omental extracts. The substances all contain lipid components. In addition, related commercially available lipid containing molecules, such as mono-, di-, and trisialogangliosides are found to pos... | 08/23/1988 |
| 4765987 | Artificial surfactants, pharmaceutical compositions containing them and use thereof New artificial surfactants composed of dipalmitoylphosphatidylcholine, distearoylphosphatidylcholine and soya lecithin and pharmaceutical compositions containing them, which can be used to replace deficient endogenous pulmonary surfactant.... | 08/23/1988 |
| 4764508 | Complexes of flavanolignans with phospholipids, preparation thereof and associated pharmaceutical compositions The invention relates to novel compounds comprising lipophilic complexes of silybin, silidianin, and silicristin with phospholipids, and the preparation of these complexes by non-conventional methods. Absorption of the novel compounds in the gastrointesti... | 08/16/1988 |
| 4762658 | Method of tableting of de-oiled phosphatides (lecithin) A method of tableting de-oiled phosphatides (lecithin) where the moisture content of granular lecithin is maintained below about 1% the aerated density above about 0.38 grams per cubic centimeter and the percent compressibility below about 15%.... | 08/09/1988 |
| 4761288 | Multiphase liposomal drug delivery system The present invention provides a novel multiphase drug delivery system which comprises: (a) lipid vesicles with a biologically active compound captured therein; (b) a saturated solution of the biologically active compound; and (c) the biologically active compound i... | 08/02/1988 |
| 4749522 | Supercritical fluid extraction of animal derived materials Supercritical fluids (SCF) are found to be useful in extracting desired materials from animal tissues, cells, and organs. By varying the choice of SCF, experimental conditions, and animal source material, one may obtain lipids, proteins, nucleotides, sacc... | 06/07/1988 |
| 4743585 | Renin inhibitors The invention concerns novel renin-inhibitory peptides which are useful for treating renin associated hypertension and for treating hyperaldosteronism. Novel intermediates, processes for preparing both the intermediates and the novel peptides, pharmaceuti... | 05/10/1988 |
| 4737364 | Nutritional dry food concentrate A highly nutritional dry food concentrate consisting entirely of plant and other non-animal natural components having a low caloric content and containing no added simple sugars. The nutritional dry food concentrate consisting entirely of natural ingredie... | 04/12/1988 |
| 4721612 | Steroidal liposomes Methods and compositions are described for the preparation of lipid vesicles, the bilayers of which comprise a salt form of an organic acid derivative of a sterol such as the tris-salt form of a sterol hemisuccinate. The method is rapid, efficient, and do... | 01/26/1988 |
| 4721618 | Method for controlling bleeding Factor VIII:C deficiency in a hemophilic mammal may be bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture a... | 01/26/1988 |
| 4721706 | Controlling grain insects with phosphatides Insect infestation of grain is controlled by contacting the grain, or a locus separating the grain from an insect population, with an insecticidally effective amount of a liquid comprising a concentration of phosphatides greater than that found in crude v... | 01/26/1988 |
| 4719111 | Novel composition for treatment of decubitus ulcers A composition for treatment of decubitus ulcers comprising an admixture of from about 10 to about 50 parts lecithin, from about 10 to about 50 parts goldenseal root or rhizome, and from about 10 to about 50 parts myrrh gum.... | 01/12/1988 |
| 4713376 | Dementia-improving and therapeutic agents An improving and therapeutic agent for neuropsychiatric symptoms accompanying dementia, which comprises, as an active ingredient, an acyloxyalkanoylcholine salt represented by the following general formula: ##STR1## wherein R1 and R2 | 12/15/1987 |
| 4698362 | Low viscosity oil based pesticide compositions The present disclosure is concerned with a technique for producing storage stable, non-caking, low viscosity pesticidal concentrates and the compositions so obtained. The technique involves milling a solid biologically active compound in a low viscosity a... | 10/06/1987 |
| 4687762 | Water soluble drug complex and method for production of same The invention provides a method of producing a water-soluble complex comprising a water-insoluble drug and a phospholipid, comprising the steps of (1) dissolving a water-insoluble drug and a phospholipid in an organic solvent, (2) removing the solvent to ... | 08/18/1987 |
| 4687766 | Pharmaceutical preparation for the therapeutic treatment of rheumatic diseases Pharmaceutical preparation containing phospholipids for the therapeutic treatment of rheumatic diseases which contain in addition to the antiphlogistically acting oxicam derivatives of the general formula ##STR1## special 1,2-diacyl-glycero-3-phospho... | 08/18/1987 |
| 4684633 | Phospholipid-emulsified prostaglandin composition A prostaglandin emulsion composition comprising a prostaglandin emulsified with a phosphatidylethanolamine-free phospholipid, the composition being suitable for intravenous administration.... | 08/04/1987 |
| 4684632 | Formulation with special 1,2-diacylglycero-3-phosphocholines for the treatment of gastrointestinal disorders Pharmaceutical formulations for the treatment of gastrointestinal disorders, which contain as the active component an effective gastrointestinal disorder alleviating amount of a 1,2-diacylglycero-3-phosphocholine in which 75-86% by weight of the acyl ... | 08/04/1987 |
| 4684520 | Pharmaceutical compositions having cerebral antianoxic and metabolic activities The invention relates to novel pharmaceutical compositions containing ubiquinone, particularly Coenzyme Q10, and mixtures of phospholipids having organic or vegetal origin, in weight-ratios ranging from 1/1 to 1/100,000, together with pharmaceu... | 08/04/1987 |
| 4678808 | Rapid acting intravenous emulsions of omega-3 fatty acid esters Described are lipid emulsions of marine oils comprising high concentrations of omega-3-fatty acid esters and low concentrations of free fatty acids for intraveneous administration for the treatment of thrombic disease states. More specifically, a lipid em... | 07/07/1987 |
| 4677099 | Medical processes employing a novel lipid fraction The invention concerns novel lipid extracts obtainable from natural sources such as egg, yolk or soyabean; and useful for treating various diseases and physiologic conditions.... | 06/30/1987 |
| 4675310 | Liposome composition as gas transport agents The invention herein involves the use of ligands and phospholipid liposomes as a carrier for the transport of various gases.... | 06/23/1987 |
