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| Number | Title | Issue Date |
| 6248728 | Phosphatidylcholine compositions and methods for lowering intestinal absorption and plasma levels of cholesterol A method and composition for reducing the intestinal absorption of cholesterol in humans or animals are provided. Broadly, the methods comprise ingesting a composition (or a food product including the composition) comprising a substituted phosphatidylchol... | 06/19/2001 |
| 6235308 | Method of treating hypertension A method of treating hypertension and related symptoms thereof is described. A suspension of small, unilamellar vesicles composed primarily of phospholipids similar in nature to those of egg phosphatidylcholine is administered parenterally to a subject in... | 05/22/2001 |
| 6210687 | Fat emulsion containing xanthine derivative An oil-in-water emulsion containing a xanthine derivative represented by ##STR1## or its pharmacologically acceptable salt, wherein the xanthine derivative or salt is present within an oil phase of the emulsion.... | 04/03/2001 |
| 6210611 | Methods for producing gas microbubbles having lipid-containing shells formed thereon A method for producing a gas microbubble comprises subjecting the gas microbubble to isothermal conditions or cooling conditions such that the lipid-containing shell cools at a rate ranging from about 100° C./min. to about 103° C./... | 04/03/2001 |
| 6200571 | Methods and compositions for the treatment of sexual dysfunction in humans and animals Therapeutic composition for the treatment of sexual dysfunction and infertility in humans and animals and methods for the treatment of sexual dysfunction and infertility and the improvement of sexual desire in humans and animals by the administration of t... | 03/13/2001 |
| 6194401 | Pharmaceutical compositions containing cyclosporine and a carrier comprising at least an ester of -glycerophosphoric acid A description is given of new pharmaceutical compositions containing cyclosporine, combined with a carrier comprising at least a derivative of -glycerophosphoric acid, such as -glycerophosphorylcholine, -glycerophosphorylserine, ... | 02/27/2001 |
| 6191121 | Treatment of skin damage using polyenylphosphatidylcholine Polyenylphosphatidylcholine is topically applied to treat skin damage, such as contact dermatitis (particularly diaper area dermatitis), atopic dermatitis, xerosis, eczema (including severe hand and foot eczema), rosacea, seborrhea, psoriasis, thermal and... | 02/20/2001 |
| 6180139 | Composition and method for treating nonalcoholic steatohepatitis Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is obs... | 01/30/2001 |
| 6180142 | Reduction of surfactant inactivation in pulmonary surfactant therapy Nonionic hydrophilic polymers or carbohydrates are administered either individually or in conjunction with therapeutically active pulmonary surfactants for the treatment of a variety of lung ailments. Included among the activities of these agents is their... | 01/30/2001 |
| 6140314 | Selective and non-invasive visualization or treatment of vasculature Disclosed are methods and materials for visualizing or treating vasculature. The methods and materials in this invention relate to selective and non-invasive visualization, or treatment such as chemical occlusion, of vasculature in the mammalian eye. The ... | 10/31/2000 |
| 6136796 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 10/24/2000 |
| 6136357 | Pharmaceutical preparation containing cyclosporin(S) for oral administration and process for producing the said preparation Cyclosporin(s) are formulated as a pharmaceutical preparation that provides good and uniform resorption of the cyclosporin(s) with no nonphysiological pharmaceutical adjuvants, by combining the cyclosporin(s) with (i) monoglycerides, diglycerides, and/or ... | 10/24/2000 |
| 6133249 | Phospholipid and propylene glycol based lubricant A method of lubrication of a mammalian joint or other physiological articulation which comprises administering a composition comprising one or more phospholipids in association with propylene glycol.... | 10/17/2000 |
| 6127349 | Phospholipid drug derivatives Disclosed herein are methods for increasing the bioavailability of pharmaceutical agents by conjugation to phospholipids. Also disclosed are phospholipid-derivatized steroids, peptides, antibiotics and other biologically active agents and pharmaceutical f... | 10/03/2000 |
| 6117853 | Cerebration improver A cerebration improver having a prominent action for increasing brain glucose level has an effect of improving the cerebration of a subject administered with the improver. The cerebration improver contains as the effective ingredient phosphatidyl-L-serine... | 09/12/2000 |
| 6113949 | Weight control product and method of treating hyperlipidemia and increasing vigor with said product This invention relates to a weight control composition, preferably in the form of a capsule or tablet, comprising a mixture of guggul extract and at least one phosphate salt selected from calcium phosphate, potassium phosphate and sodium phosphate. The co... | 09/05/2000 |
| 6086884 | Composition for treating impotence in men containing dried roe and yohimbine A composition for treating impotence in human males contains a synergistic mixture of dried sturgeon roe and yohimbine hydrochloride wherein the weight percent ratio of said dried sturgeon roe:yohimbine hydrochloride is from about 25:1 to 1000:1, with an ... | 07/11/2000 |
| 6080787 | Methods for reducing the incidence of necrotizing enterocolitis Enteral formulas that contain long-chain polyunsaturated fatty acids (PUFAs), as arachidonic acid (AA) and docosahexaenoic acid (DHA) that are essentially free of cholesterol, are described. More particularly, the invention relates to methods for reducing... | 06/27/2000 |
| 6080422 | Methods of angioplasty and cardiac catheterization The present invention provides an improved mode of operation of an apparatus for angioplasty or cardiac catheterization, apparatus for angioplasty and cardiac catheterization, and method of angioplasty or cardiac catheterization. The improvement and impro... | 06/27/2000 |
| 6077529 | Active ingredient system and method of manufacture thereof for transfer of lipophilic and amphiphilic components to target structures Active ingredient system for the lipid exchange with target structures; methods for their manufacture and their use; and products containing active ingredient systems of this type are disclosed. The active ingredient system for the transfer of lipophilic ... | 06/20/2000 |
| 6069138 | Use of phospholipids of animal origin in therapy and/or dietetics The invention concerns a novel use of phospholipids of animal origin in therapy and/or dietetics, more particularly the use of phospholipids rich in long-chain polyunsaturated fatty acids derived from animal brains or hen's eggs, to produce a pharmaceutic... | 05/30/2000 |
| 6054494 | Phospholipid composition The present invention relates to a phospholipid composition comprising two or more phospholipids, the electric conductivity and pH of a 5 wt. % suspension of the phospholipid composition in deionized water being in the range of 130 to 220 μS/cm and in th... | 04/25/2000 |
| 6054133 | Anti-microbial targeting for intracellular pathogens A method and composition are provided for treating intracellular pathogens that reside in phagosomes. The compositions include antibiotics which are conjugated with transferrin or other ligands to form conjugates that target membrane-bound pathogens. The ... | 04/25/2000 |
| 6034130 | Lipid composition for infant formula and method of preparation Synthetic lipid composition in which the content and the distribution of the fatty acids are similar to those of human milk fat, containing less than 2% by weight of free fatty acids, in which palmitic acid is predominantly at the 2-position of the triacy... | 03/07/2000 |
| 6022560 | Pharmaceutical compositions, novel uses, and novel form of -tocopherylphosphocholine -Tocopherylphosphocholine and salts thereof have been discovered to possess antiviral, anti-fungal, anti-inflammatory, PAF-antagonist, and ultra-violet radiation-blocking activities. The compound and salts have also been discovered to be capable of... | 02/08/2000 |
| 6017891 | Stable preparation for the treatment of blood coagulation disorders The invention relates to a stable preparation which comprises a protein, such as thrombin, that is bound in and/or on (i.e., to) lipid vesicles and that was treated for the inactivation of potentially present viruses. Further, the invention relates to met... | 01/25/2000 |
| 6015798 | Method for reducing the damaging effects of radiation therapy on animal skin and mucosa The severity of damage caused to the skin and mucosa of animals with cancer undergoing radiation therapy is mitigated by feeding the animal a nutritionally balanced food composition containing omega-6 polyunsaturated fatty acids which are supplemented wit... | 01/18/2000 |
| 6011022 | Topical application of muscarinic analgesic drugs such as neostigmine The invention is directed to methods and pharmaceutical compositions for the topical administration of analgesic drugs which affects peripheral muscarinic receptors such as neostigmine. In particular, the invention relates to topical administration of an ... | 01/04/2000 |
| 6004566 | Topical and transdermal delivery system utilizing submicron oil spheres The present invention relates to a delivery system which includes a bioactive drug or cosmetic substance presented in the form of submicron oil spheres alone, or drugs or cosmetic substances in a combination with the oil spheres in an aqueous suspension o... | 12/21/1999 |
| 6004579 | Compositions which inhibit apoptosis, methods of making the compositions and uses thereof The present invention provides compositions that inhibit apoptosis, methods for making the compositions, and methods of use thereof.... | 12/21/1999 |
| 5997888 | Cosmetic preparations The cosmetic preparation contains: (a) an oil-soluble active ingredient that is suitable for skin cosmetics, (b) a partial fatty acid ester of polyoxyethylene sorbitan, (c) at least one phospholipid, (d) ethanol, and (e) water as a carrier liquid. The pho... | 12/07/1999 |
| 5994322 | Compositions for preventing dementia Compositions for preventing or treating memory loss in the brain, comprising an effective amount of a mixture of lecithin and vitamin B12.... | 11/30/1999 |
| 5985854 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 11/16/1999 |
| 5965519 | Covalent polar lipid conjugates with biologically-active compounds for use in salves This invention herein describes a method of facilitating the entry of drugs into cells and tissues at pharmokinetically useful levels and also a method of targeting drugs to specific organelles within the cell. This polar lipid/drug conjugate targeting in... | 10/12/1999 |
| 5965623 | Anti-glucocorticoid drug Somatic mammary cells are defended from an action of glucocorticoid hormones by an insect pheromones of non-steroid nature, its derivative or a synthetic analog.... | 10/12/1999 |
| 5958463 | Agricultural pesticide formulations The present invention relates generally to the method for the production of liposomal microencapsulated boron-containing products to be used for agricultural formulations. More specifically, a new method of production of liposomal microencapsulated is dis... | 09/28/1999 |
| 5955451 | Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein Disclosed are compositions comprising non-steroid anti-inflammatory drugs (NSAID'S) complexed with zwitterionic, neutral phospholipids, or both, having reduced gastrointestinal irritating effects and enhanced antipyretic, analgesic, and antiinflammatory a... | 09/21/1999 |
| 5948441 | Method for size separation of particles Tangential flow filtration is used in the size separation of particles, such as liposomes and lipid particles. These particles may be passed through a tangential flow filtration device of any pore size desired. Tangential flow filter systems of various po... | 09/07/1999 |
| 5945420 | Immunopotentiating and infection protective agent and production thereof An immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin derivative, which is safe for the human, animals or the like, an immunopotentiating and infection protective agent comprising riboflavin and/or a riboflavin der... | 08/31/1999 |
| 5945409 | Topical moisturizing composition and method The present invention comprises methods and compositions for topically treating and moisturizing keratinous structures of humans and animals including skin, hair, fingernails, toenails, hooves, and horns.... | 08/31/1999 |
