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| Number | Title | Issue Date |
| 8026286 | Pharmaceutical compositions providing enhanced drug concentrations A drug in a solubility-improved form is combined with a concentration-enhancing polymer in a sufficient amount so that the combination provides substantially enhanced drug concentration in a use environment relative to a control comprising the same amount of the sam... | 09/27/2011 |
| 7759400 | Pressure-sensitive adhesive composition and skin patch It is intended to provide a composition which has well-balanced pressure-sensitive adhesiveness and cohesive force as well as favorable application properties to the skin, and a patch which has the above-described characteristics and hardly peels off. This object ca... | 07/20/2010 |
| 7442721 | Durable biocompatible controlled drug release polymeric coatings for medical devices Disclosed herein are biocompatible durable controlled drug releasing polymeric coatings for medical devices. The drug release rates of the polymers are controlled by adjusting monomer ratios and glass transition temperatures Tgs. The polymers are durable; they do no... | 10/28/2008 |
| 7425581 | Temperature sensitive polymers The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the applicati... | 09/16/2008 |
| 7381424 | Hydrostatic delivery system for controlled delivery of agent The present invention provides a hydrostatic delivery system comprising a hydrostatic couple and an agent of interest. The hydrostatic couple comprises, at least one hydrodynamic fluid-imbibing polymer, and at least one hydrostatic pressure modulating agent. This de... | 06/03/2008 |
| 7368125 | Amphiphilic polymers for medical applications The present invention is directed to medical devices or pharmaceutical compositions, each containing a synthetic, bioabsorbable, biocompatible polymer that is the reaction product of a polybasic acid or derivative thereof, a monoglyceride, and a polyether. ... | 05/06/2008 |
| 7342047 | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups The present invention provides cross linkable compositions useful in the preparation of hydrophilic gels, and are prepared from obligers having pendent hydrophilic ploy(alkenylene oxide) groups, and pendent pulverizable functional groups, and cross linked by polyfun... | 03/11/2008 |
| 7332155 | Surfactant-containing cosmetic, dermatological and pharmaceutical agents The invention provides surfactant-containing cosmetic, dermatological, and pharmaceutical agents comprising at least one water-soluble or water-swellable copolymer obtainable by free-radical copolymerization of A) acryloyldimethyltaurine and/or acryloyl... | 02/19/2008 |
| 7297328 | Surfactant-free cosmetic, dermatological and pharmaceutical agents The invention provides a surfactant-free cosmetic, dermatological, and pharmaceutical agents comprising at least one copolymer obtainable by free-radical copolymerization of A) acryloyldimethyltaurine and/or acryloyldimethyltaurates, B) opt... | 11/20/2007 |
| 7294345 | Otorhinological delivery device The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least one pharmaceutically active agent wherein said core is made of an elast... | 11/13/2007 |
| 7279154 | Use of comb copolymers based on acryloyldimethyltaurine acid in cosmetic, pharmaceutical and dermatological products The invention relates to uses of comb polymers of acryloyldimethyltaurine and/or acryloyldimethyltaurates in cosmetic, pharmaceutical and dermatological applications as thickeners, dispersing agents, suspending agents, emulsifiers, stabilizers, solubilizers, conditi... | 10/09/2007 |
| 7256180 | Compositions and methods for inducing activation of dendritic cells Compositions induce the activation of dendritic cells comprising a polynucleotide, such as viruses, RNA, DNA, plasmid DNA, or derivatives thereof and at least one block copolymer of alkylethers. The present invention further relates to compositions for inducing the ... | 08/14/2007 |
| 7244421 | Cosmetic and dermatological hair-treatment agents The invention relates to cosmetic and dermatological hair treatment compositions comprising at least one copolymer. The copolymer is obtained by free-radical copolymerization of A) acryloyldimethyltaurine and/or acryloyldimethyltau... | 07/17/2007 |
| 7226952 | Gel composition and its use in cosmetic compositions and the like A gel composition and cosmetic composition and the like that can excel in pigment and/or filler uniformity and stability and can have a good outer appearance even when further comprising a relatively large amount of pigments. A gel composition is formed by combining... | 06/05/2007 |
| 7220431 | Methods and compositions for applying pharmacologic agents to the ear Methods and materials useful for applying pharmacologic agents to the ear are described. The methods involve delivering a composition that contains at least one viscogenic agent and at least one pharmacologic agent to the epidermal surface of the tympanic membrane v... | 05/22/2007 |
| 7214381 | Composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels The present invention refers to a pharmaceutical composition suitable for the transdermal or transmucosal administration of one or more active agents, in form of a gel or a solution, comprising as a permeation enhancers a combination of: a) saturated fatty alcohol o... | 05/08/2007 |
| 7204997 | Responsive microgel and methods related thereto A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked ho... | 04/17/2007 |
| 7202326 | Glycolic acid copolymer and method for production thereof A glycolic acid copolymer comprising (a) 80 to less than 95% by mole of glycolic acid monomer units, (b) 5.0 to 20.0% by mole of non-glycolic, hydroxycarboxylic acid monomer units, and (c) 0 to 0.10% by mole of diglycolic acid monomer units, the non-glycolic, hydrox... | 04/10/2007 |
| 7192984 | Compositions of polyacids and polyethers and methods for their use as dermal fillers The present invention relates to improved methods for filling the skin for cosmetic or medical purposes. Compositions comprising carboxymethyl cellulose (CMC), polyethylene oxide (PEO) and calcium ions can be made and have physical properties that depend on the amou... | 03/20/2007 |
| 7189267 | Oxyethylenated based hair pre-treatment anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin The present invention generally relates to a hair pre-treatment anti-penetration composition comprising an efficient amount of at least one oxyethylenated copolymer. The invention also relates to a method for limiting the penetration into the skin and/or the keratin... | 03/13/2007 |
| 7172755 | Methods for making functionalized polymers Polymers containing amino acid and/or polypeptide moieties in their backbones or pendant to their backbones are made by metathesis. A method of making an amino acid or polypeptide containing polymer includes the steps of: providing a amino acid, amino alcohol, or po... | 02/06/2007 |
| 7160902 | Amide derivatives and methods of their use Amide derivatives of the general formulae Ia and Ib: are disclosed. Pharmaceutical compositions containing these compounds, and methods for their use, inter alia, for treating and/or preventing gastrointestinal d... | 01/09/2007 |
| 7153526 | Treatment of gastrointestinal infections A method for combating bacterial infections affecting the gastrointestinal system of humans and animals is provided. The method is achieved by diagnosing a bacterial infection affecting the gastrointestinal system and periodically administering a dosage of concentra... | 12/26/2006 |
| 7138121 | Biosensors utilizing dendrimer-immobilized ligands and there use thereof The present invention is directed to methods and compositions useful as biosensors that specifically interact with various pathogens and other target analytes. The biosensor itself, comprises functionalized dendritic tethers derivatized for attachment to a variety o... | 11/21/2006 |
| 7135442 | Lens care product containing dexpanthenol The present invention relates to contact lens care product comprising dexpanthenol. The invention similarly relates to the usage of a contact lens care compositions of this kind for cleaning and optionally disinfecting contact lenses. ... | 11/14/2006 |
| 7115641 | Antimicrobial oxazolidine/iodopropynyl-butyl carbamate composition containing less than 0.1wt% free formaldehyde This invention relates to a broad spectrum antimicrobial composition, effective against gram negative and gram positive bacteria and fungi, which comprises a synergistic composition comprising iodopropynyl butyl carbamate and a bicyclic hydroxymethyl oxazolidine con... | 10/03/2006 |
| 7109237 | Emulsion containing ascorbic acid and its uses in the cosmetics and dermatological fields A water-in-oil emulsion containing ascorbic acid and, as an emulsifier, a dimethiconecopolyol or an alkyldimethiconecopolyol, where the aqueous phase having a pH ranging from 5.5 to 7.5. This emulsion allows ascorbic acid to be stabilized and can be used, in particu... | 09/19/2006 |
| 7101928 | Polymeric thickeners for oil-containing compositions Novel thickeners for oil-containing compositions are crystalline polymers, preferably side chain crystalline polymers, which (a) have a crystalline melting point, Tp, and an onset of melting temperature, To, such that Tp−To | 09/05/2006 |
| 7101572 | Taste masked aqueous liquid pharmaceutical composition A substantially taste masked liquid pharmaceutical composition containing a pharmaceutically effective amount of an unpleasant tasting drug dissolved or dispersed in an aqueous excipient base, said excipient base comprising polyvinyl pyrrolidone and/or copolyvidone,... | 09/05/2006 |
| 7101566 | Polymer coated microparticles for sustained release The present invention is directed to sustained release microparticle formulation for parenteral administration of biologically active substances, especially drugs. More specifically it relates to coated drug containing microparticles, wherein the coating is a synthe... | 09/05/2006 |
| 7101840 | Polymeric drug formulations A method of forming a polymeric drug formulation in which a water-soluble drug is blended with a water-insoluble tissue-compatible polymer that is miscible in the solid phase with the drug, and with a poly(alkylene oxide), in a solvent system capable of forming a ho... | 09/05/2006 |
| 7087263 | Rare limiting barriers for implantable medical devices A coating for a medical device, particularly for a drug eluting stent, is described. The coating comprises a polymer having a weight-average molecular weight between about 200,000 and about 250,000 Daltons or a polydispersity index between about 2.6 and about 3.0. | 08/08/2006 |
| 7078049 | Ultrafine emulsion containing a haloalkynyl derivative A composition in the form of an ultrafine oil-in-water emulsion in which the mean size of the oil globules ranges from 50 nm to 1000 nm containing a haloalkynyl derivative, preferably 3-iodo-2-propynyl butylcarbamate. ... | 07/18/2006 |
| 7070797 | Method of treating hematologic tumors and cancers Multiple myeloma and other hematologic tumors and/or malignancies can be treated by administration of a G1 and/or S phase drug, which is preferably β-lapachone, or a derivative or analog thereof, combined with a G2/M phase drug such as a taxane derivative, which is... | 07/04/2006 |
| 7034051 | Fused bicyclic carboxamide derivatives and methods of their use Fused bicyclic carboxamide derivatives are disclosed. Pharmaceutical compositions containing the compounds and methods for their use are also disclosed. ... | 04/25/2006 |
| 7033604 | Composition for topical administration The present invention provides a composition for topical administration comprising an interleukin 2 inhibitor and an antimicrobial agent as active ingredients thereof, wherein said interleukin 2 inhibitor contains a tricyclo compound as shown by the general formula ... | 04/25/2006 |
| 7030149 | Combination of brimonidine timolol for topical ophthalmic use Disclosed are pharmaceutical compositions comprising brimondine and timolol for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for glaucoma and associated conditions such as elevated intraocular pressur... | 04/18/2006 |
| 7022315 | Administration of a thiol-based chemoprotectant compound A method of administration of a thiol-based chemoprotectant agent including NAC (N-acetylcysteine) and STS (sodium thiosulfate) that markedly affects biodistribution and protects against injury from diagnostic or therapeutic intra-arterial procedures. A method for t... | 04/04/2006 |
| 7022791 | Cosmetic, pharmaceutical and dermatological products containing an electrolyte The invention relates to cosmetic, dermatological, and pharmaceutical products containing an electrolyte. The products are obtained by free-radical copolymerization of A) acryloyldimethyltaurine and/or acryloyldimethyltaurates, and... | 04/04/2006 |
| 7001607 | Artificial tear replacement solution A tear replacement solution that contains at least one water-soluble fluorosurfactant, water and a non-polar component, preferably in gel form, and a method for the external treatment for the eye of an mammal by applying the tear replacement solution to the eye, pre... | 02/21/2006 |
