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| Number | Title | Issue Date |
| 8003705 | Biocompatible hydrogels made with small molecule precursors Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic functional groups capable of reacting and cros... | 08/23/2011 |
| 7964650 | Carbonyl-functionalized thiophene compounds and related device structures Carbonyl-functionalized oligo/polythiophene compounds, and related semiconductor components and related device structures. ... | 06/21/2011 |
| 7951846 | pH-sensitive polymeric micelles for drug delivery Mixed micelles containing poly(L-histidine)-poly(ethylene glycol) block copolymer and poly(L-lactic acid)-poly(ethylene glycol) block copolymer are a pH-sensitive drug carrier that release the drug in an acidic microenvironment, but not in the blood. Since the micro... | 05/31/2011 |
| 7807722 | Biobeneficial coating compositions and methods of making and using thereof A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, and a method of coating the device with the composition, and an implantable device coated with the composition are provided. ... | 10/05/2010 |
| 7776926 | Biocompatible coating for implantable medical devices A random or a block copolymer which includes at least one biologically compatible structural moiety and at least one biologically active moiety is disclosed. The random or block copolymer can be used for fabricating a coating for an implantable medical device such a... | 08/17/2010 |
| 7763663 | Polysaccharide-containing block copolymer particles and uses thereof The invention relates to new amphiphilic linear block copolymers of polysaccharides and polymers. The amphiphilic linear block copolymers do not form a true solution in water and are able to form micelles in selective solvents. Also disclosed are particles, each of ... | 07/27/2010 |
| 7659314 | PH-sensitive polymeric micelles for drug delivery Mixed micelles containing poly(L-histidine)-poly(ethylene glycol) block copolymer and poly(L-lactic acid)-poly(ethylene glycol) block copolymer are a pH-sensitive drug carrier that release the drug in an acidic microenvironment, but not in the blood. Since the micro... | 02/09/2010 |
| 7655702 | Foaming emulsions and foaming compositions containing a polymer comprising water-soluble units and units with an LCST, especially for cosmetic uses A method of lowering the surface tension or the interface tension of water in cosmetic compositions comprising at least one cosmetic or dermatological adjuvant, the method comprising adding a polymer comprising water-soluble units and units with an LCST, wherein the... | 02/02/2010 |
| 7649023 | Biodegradable block copolymeric compositions for drug delivery An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mix... | 01/19/2010 |
| 7638558 | Polymeric micelles for drug delivery The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. ... | 12/29/2009 |
| 7563824 | Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals A clathrate formed by: a hyaluronic acid derivative (a), a hyaluronic acid derivative (b1) different from (a), and being able to form a clathrate with (a) and/or a component (b2) not containing a hyaluronic acid moiety but being able to form with (a) a... | 07/21/2009 |
| 7560492 | Polysulfone block copolymers as drug-eluting coating material A polymeric composition comprising a polysulfone polymer and an elastomeric polymer for use as a coating composition for coating an implantable device, such as a DES, and methods of making and using the implantable device are provided. ... | 07/14/2009 |
| 7528176 | Carbonyl-functionalized thiophene compounds and related device structures Carbonyl-functionalized oligo/polythiophene compounds, and related semiconductor components and related device structures. ... | 05/05/2009 |
| 7517914 | Controlled degradation materials for therapeutic agent delivery According to an aspect of the present invention, polymeric release regions are provided, which contain one or more partially biodegradable progenitor polymers and which control the release of one or more therapeutic agents disposed beneath or within the same. The pr... | 04/14/2009 |
| 7429619 | Polyacrylic film forming compositions Water soluble, gelatin-free dip coatings for substrates comprising an acrylic film former; a paraben plasticizer; and a secondary plasticizer such as polyvinylpyrrolidone, polyethylene glycol 300, polyethylene glycol 400 or mixtures thereof. ... | 09/30/2008 |
| 7425581 | Temperature sensitive polymers The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the applicati... | 09/16/2008 |
| 7407671 | Temperature controlled solute delivery system A system for delivering solute to a target location within a mammalian body, the system including a medical device, a thermosensitive cellulose gel structure over the medical device, and a biologically active solute within said gel structure. The gel structure deswe... | 08/05/2008 |
| 7388032 | Sustained release compositions, process for producing the same and utilization thereof A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition containing said sustained-release composition. ... | 06/17/2008 |
| 7384984 | Reactive hydrophilic oligomers Hydrophilic compositions are described, which are prepared from a first component oligomer containing pendent hydrophilic groups and pendent reactive functional groups capable of reaction at effective rates (at normal processing temperatures), with a co-reactive sec... | 06/10/2008 |
| 7371781 | Tumor environment-induced ligand-expressing nanocarrier system Drug delivery compositions for specific delivery of a drug to a tumor are described. These compositions include a core for sequestering the drug and a shell to which a ligand is attached for delivery of a drug to target cells. Since normal cells may also be targeted... | 05/13/2008 |
| 7351430 | Shape-retentive hydrogel particle aggregates and their uses The present invention is related to hydrogel particles and aggregates formed therefrom having characteristics including, without limitation, shape-retentiveness, elasticity, controllable pore sizes and controllable degradation rates that render them useful for a wid... | 04/01/2008 |
| 7348364 | Segmented copolyesters as compliant, absorbable coatings and sealants for vascular devices Disclosed are absorbable sealants or coatings for biomedical devices which are formulated from a segmented copolyester having a molecular weight of more than 5 kDa, a glass transition temperature of less than 35° C., and low degree of crystallinity evidenced by a h... | 03/25/2008 |
| 7342047 | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups The present invention provides cross linkable compositions useful in the preparation of hydrophilic gels, and are prepared from obligers having pendent hydrophilic ploy(alkenylene oxide) groups, and pendent pulverizable functional groups, and cross linked by polyfun... | 03/11/2008 |
| 7338663 | Expandable osmotic composition and coating suspension The present invention includes an expandable osmotic layer and a coating suspension for providing an expandable osmotic layer, both of which are useful for the manufacture of controlled release dosage forms. The expandable osmotic layer of the present invention may ... | 03/04/2008 |
| 7335675 | Aqueous suspension formulation for foliar application fungicide The present invention provides an aqueous suspension formulation containing (RS)-N-[2-(1,3-dimethylbutyl)thiophene-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide and having high rain resistance and stable residual effectiveness. A aqueous suspensi... | 02/26/2008 |
| 7332527 | Cross-linked ionic core micelles The present invention provides polymer micelles with cross-linked ionic cores as delivery vehicles for therapeutics, diagnostics, nucleic acids, proteins, small molecules and the like. The present invention provides additionally methods of synthesis and uses for suc... | 02/19/2008 |
| 7326425 | Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release A formulation containing a biologically active compound having a structure with hydrogen bonding sites blended with a first polymer having a structure with complementary hydrogen bonding sites and a second polymer that degrades to form degradation products that prom... | 02/05/2008 |
| 7317070 | Process for the preparation of polyamino acids Among the various aspects of the present invention is an improved process for the preparation of polyamino acids generally, and more specifically, polyglutamic acid and polyaspartic acid. Another aspect is a process for the large scale (i.e. >1 kg) preparation of po... | 01/08/2008 |
| 7314611 | Solution and method for treating organic waste An odor control product for treating digestible and odiferous organic waste to minimize odors includes about 12.5% adipic acid, about 70% alcohol, about 0.5% eucalyptus oil, and the remainder water. A variation of the product for use in an atomization system include... | 01/01/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7309756 | Methods for converting linear polyesters to macrocyclic oligoester compositions and macrocyclic oligoesters Macrocyclic oligoesters and compositions comprising macrocyclic oligoesters are prepared from intermediate molecular weight polyesters. In one embodiment, a diol is contacted with a dicarboxylic acid or a dicarboxylate in the presence of a catalyst to produce a comp... | 12/18/2007 |
| 7279174 | Stent coatings comprising hydrophilic additives A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically... | 10/09/2007 |
| 7273891 | Stable copolymers A graft reverse thermal hydrogel which does not show substantial loss of complex viscosity at and up to 20 degrees above the transition temperature upon autoclaving or aging. Other embodiments include the graft reverse thermal copolymer which can be dissolved in wat... | 09/25/2007 |
| 7265157 | Sustained release compositions, process for producing the same and use thereof Sustained release compositions containing a physiologically active substance or its salt, hydroxynaphthoic acid or its salt and a lactic acid-glycolic polymer or its salt, wherein the product of the weight-average molecular weight of the lactic acid-glycolic acid po... | 09/04/2007 |
| 7244443 | Polymers of fluorinated monomers and hydrophilic monomers A polymer of fluorinated monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains a polymer of fluorinated monomers and another biocompatible polymer. The polymer of fluorinated monomers or polymer blend described herein and o... | 07/17/2007 |
| 7241813 | End-capped polymers and compositions containing such compounds End-capped polymers, methods for making those end-capped polymers and compositions containing those end-capped polymers are disclosed. One of the disclosed end-capped copolymers has the formula: and may be combin... | 07/10/2007 |
| 7241835 | Cosmetic compositions comprising silicone gels Methods for making homogenized cosmetic formulations comprising a silicone gel. ... | 07/10/2007 |
| RE39713 | Polymerizable biodegradable polymers including carbonate or dioxanone linkages Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and methods of preparation and use thereof are described. The macromers a... | 07/03/2007 |
| 7238364 | Compliant tissue sealants An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the system is compliant, in that it is capable of conforming to the three... | 07/03/2007 |
| 7223815 | Polylactic acid composition containing modifier A modifier for a polylactic acid comprising a block polymer (C) having a polymer block (A) satisfying relationship (1): 7.80≦σ/ρ | 05/29/2007 |
