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Class 514/756 - Bicyclo


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the polycyclo ring system consists
No. of patents: 38
Last issue date: 02/12/2008


NumberTitleIssue Date
7329402Methods of imaging and treatment
Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The...
02/12/2008
7252845Synergistic compositions containing aromatic compounds and terpenoids present in Alpinia galanga
Novel compositions of matter containing aromatic compounds and terpenoids which are present in and may preferably be derived from the plant Alpinia galanga (Zingiberaceae) show synergistic effects with respect to immunomodulation, and they significantly suppr...
08/07/2007
7083572Therapeutic delivery systems
Targeted therapeutic delivery systems comprising gas- or gaseous precursor-filled lipid microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Targeted therapeutic d...
08/01/2006
7078015Ultrasound imaging and treatment
Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly usefull for example, in ultrasonic imaging applications and in therapeutic dr...
07/18/2006
6998107Composition comprising low density microspheres
Low density microspheres, methods for preparing same, and use of same as contrast agents are described. The microspheres have a void having a volume that comprises at least about 75% of the total volume of the microspheres, and which contains a gas or the vapor of a...
02/14/2006
6444700Product and method to reduce stress induced immune suppression
In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress. The stress may be in the form of physical exertion, mental ...
09/03/2002
6337337Methods for treating disorders responsive to DHFR-inhibition
A method for treating disorders responsive to DHFR inhibition is disclosed, wherein the disorders may include neoplastic diseases, rheumatoid arthritis, restenosis, multiple sclerosis, lupus, infections, and ectopic pregnancy. The inventive method compris...
01/08/2002
6235796Use of fluorocarbons for the prevention of surgical adhesions
Method for the prevention and inhibition of adhesion between tissues comprising the use of fluorocarbons are disclosed. The method provides for the introduction of a fluorocarbon into the surgical site of a mammalian body, such as a human, to minimize fri...
05/22/2001
5859068Acceleration of tissue growth using fluorocarbon liquid
A method for the acceleration of tissue growth using continuous fluorocarbon liquid-based positive pressure is disclosed, whereby significant increase in tissue growth is achieved....
01/12/1999
5824703Method of assisting normal breathing in a mammal having a lung disorder
A method of assisting a mammal having a lung disorder to breathe ambient gas normally, i.e., without the assistance of a ventilator. The method includes providing an animal having a lung disorder, such as surfactant deficiency, stiff lung, or hyperinflate...
10/20/1998
5684050Stable emulsions of highly fluorinated organic compounds
Stable emulsions of highly fluorinated organic compounds for use as oxygen transport agents, "artificial bloods" or red blood cell substitutes and as contrast agents for biological imaging. The emulsions comprise a highly fluorinated organic compound, an ...
11/04/1997
5674913Method for assisting normal breathing in a mammal having a lung disorder
A method of assisting a mammal having a lung disorder to breathe ambient gas normally, i.e., without the assistance of a ventilator. The method includes providing an animal having a lung disorder, such as surfactant deficiency, stiff lung or hyperinflated...
10/07/1997
5635539Stable emulsions of highly fluorinated organic compounds
Stable emulsions of highly fluorinated organic compounds for use as oxygen transport agents, "artificial bloods" or red blood cell substitutes and as contrast agents for biological imaging. The emulsions comprise a highly fluorinated organic compound, an ...
06/03/1997
5573757Viscoelastic compositions containing concentrated fluorinated compounds their method of preparation and their uses
Compositions for topical application in gel form comprising a fluorocarbon or perfluorocarbon compound or mixtures thereof at a concentration of at least about 75% v/v, a minor quantity of a surface active agent and an aqueous phase. The compositions prov...
11/12/1996
5565460Therapeutic purine agents for parkinson's disease
The present invention relates to a therapeutic agent for Parkinson's disease containing as an active ingredient a polycyclic compound or a pharmaceutically acceptable salt thereof, the compound being represented by the following Formula (I): ##STR1##...
10/15/1996
5374624Fluorocarbon blood substitute
The present invention relates to fluorochemical blood substitutes used for preserving mammalian tissue having lysophosphatidyl compounds in non-toxic concentrations. More specifically, the invention relates to aqueous fluorochemical emulsions of a fluoroc...
12/20/1994
5270345Non-bioaccumulable pesticides
Novel pesticidal compositions, which are characterized by biodegradability and do not bioaccumulate to an unacceptable level in fats and tissues of animals, fowl and fish, containing active compounds and optionally a carrier suitable for administering sai...
12/14/1993
5104900Naphthalene based snake repellant
A new use for naphthalene comprising a snake repellant in the form of granules comprising 8% naphthalene, 32% sulfur and 60% montmorillonite. The compound is spread in a strip across an area where snakes are to be repelled and is effective against venomou...
04/14/1992
5073383Inhibiting aggregation in fluorocarbon emulsions
Aggregation of fluorocarbon emulsion particles, which occurs when the emulsion mixes with blood, is reduced by the addition of relatively large amounts of phosphate....
12/17/1991
5061484Perfluorochemical emulsion with stabilized vesicles
A stable perfluorochemical emulsion is provided which comprises perfluorochemical particles in stabilized vesicles. The vesicles comprise a biocompatible polymer formed by coating the perfluorochemical particles with one or more phospholipid monomer(s) an...
10/29/1991
4917930Perfluoro compound dispersions containing reduced amounts of surfactant and process of preparation
Compositions having enhanced gas and drug transporting capability, are prepared by providing a perfluoro compound dispersed in an aqueous medium with a surfactant to form an aqueous initial dispersion, concentrating the perfluoro compound phase of the dis...
04/17/1990
4895876Concentrated stable fluorochemical aqueous emulsions containing triglycerides
A stable concentrated aqueous emulsion of perfluorochemical, a phospholipid and a triglyceride of fatty acids has been demonstrated which has enhanced stability, diminished particle size and heightened tolerance by biological systems. The emulsion has uti...
01/23/1990
4889525Sensitization of hypoxic tumor cells and control of growth thereof
Method of sensitizing hypoxic tumor cells to radiotherapy and chemotherapy by contacting the cells or the vasculature thereof with an aqueous dispersion of an oxygen carrying perfluoro compound and a dispersant for the compound, and sensitizing chemothera...
12/26/1989
4879062Preparation of a gel having gas transporting capability
An inert, water-immiscible inert organic liquid having gas transport properties, water and a suitable emulsifying agent are formed into a stable gel by emulsifying a mixture of the same, concentrating the emulsion to form a gel phase and a liquid phase an...
11/07/1989
4866096Stable fluorochemical aqueous emulsions
A stable aqueous emulsion of perfluorochemical, a phospholipid and a triglyceride of fatty acids has been demonstrated which has enhanced stability, diminished particle size and heightened tolerance by biological systems. The emulsion has utility as an ox...
09/12/1989
4569943Physiologically active substance P-23924, its production and use
The compound of the formula: ##STR1## wherein R1 is hydrogen, methyl or hydroxymethyl, R2 is hydrogen or methoxy, R3 is hydroxy or methoxy, and R4 is hydrogen or a group ##STR2## is novel, and the...
02/11/1986
4497829Process for preparing perfluorochemical emulsion artificial blood
Particles of perfluoro compound with a lipid coating are emulsified by sonification in aqueous medium, wherein the proportion of perfluoro compound in the emulsion is preferably about 30-75% (w/v) and the proportion of lipid is preferably about 7-9% (w/v)...
02/05/1985
4490351Methods of treating disorders of an eye with liquid perfluorocarbons
Liquid perfluorocarbons and substituted derivatives thereof are used as fluid substitutes for the vitreous or the aqueous of the eye. These liquids are also used to transparentize the cornea or lens when either becomes opacifed due to degeneration or cata...
12/25/1984
4452818Extraocular method of treating the eye with liquid perfluorocarbons
Extraocular ophthalmic preparations useful as therapeutic, lubricating or protective agents are disclosed. Liquid perfluorocarbons and substituted derivatives are the active components of the ophthalmic preparations. The neat perfluorocarbon liquids are n...
06/05/1984
4443480Artificial blood and other gas transport agents
Gas transport agents such as artificial blood containing a perfluorocyclocarbon and an amine oxide are disclosed. These compositions have been found to provide transparent emulsions or solutions for use in oxygen transport, particularly in animals. Large ...
04/17/1984
4397870Process for prolonging retention of emulsion particles in the bloodstream
The retention of coated particles previously infused into the bloodstream of animals may be prolonged by one or more injections of coating substance. For example, the retention of an artificial blood composition comprising emulsified lecithin-coated perfl...
08/09/1983
4395393Artificial blood emulsifiers
An artificial blood composition comprises a perfluoro chemical, physiological saline and a polyoxybutylene-polyoxyethylene block copolymer. The block copolymer provides stable emulsions....
07/26/1983
4366169Use of perfluorocarbons as wound treatment
Victims suffering certain types of wounds are treated by contacting the wound with a substantially fluorinated carbon material or a mono- or di-brominated derivative thereof containing molecular oxygen....
12/28/1982
4201791Pesticide powders, their use and preparation
An at least partially water insoluble powder containing a pesticide in admixture with an inert diluent wherein the pesticide is incorporated within the powder during its formation. The powder can be manufactured by directly admixing the pesticide, i.e., a...
05/06/1980
4105798Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
Novel emulsions of non-aromatizable perfluorinated compounds are useful as blood substitutes or as perfusion materials for the storage of organs such as kidneys prior to transplant. The compounds employed are polycyclic compounds and emulsions prepared fr...
08/08/1978
4053632Compounds of spiro-amine type and methods for their use
Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof; processes for their preparation; intermediates useful for their preparation; pharmaceutical preparations containing at least one of these compounds; and the use the...
10/11/1977
3992532Flowable pesticide formulations
Disclosed herein are flowable pesticide formulations comprising; 40-60% by weight of the total formulation of a liquid water-insoluble toxicant or mixture of toxicants, 1-25% weight of the total formulation of a hydrocarbon oil from the group consisting e...
11/16/1976
3962439Oxygen-transferable emulsion
Oxygen-transferable perfluorocarbon compounds having 9 to 11 carbon atoms such as perfluorodecalin, perfluoro(C3-5 -alkylcyclohexanes), perfluoro(C4-6 -alkyl tetrahydropyrans), perfluoro(C5-7 -alkyltetrahydrofurans), perfl...
06/08/1976
 
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