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| Number | Title | Issue Date |
| 8158684 | Estrogenic compounds, process for their production and pharmaceutical uses thereof The present invention provides new estrogenic compounds of the general formula in which the substituents have the meanings that are explained in more detail in the description, and pharmaceutical compositions containing the... | 04/17/2012 |
| 8058316 | STAT3 inhibiting compositions and methods A composition may include a pharmaceutical carrier and an amount, therapeutically effective for the treatment of a retinal disease, of CLT-005 (1-acetyl-5-hydroxyanthracene-9,10 -dione), wherein the retinal disease is characterized by at least one of inflammation, a... | 11/15/2011 |
| 7709538 | ST104P, an anti-angiogenic agent The present invention relates to a method of treating a non-tumor condition or disease associated with angiogenesis in a human or animal comprises administering thereto an effective angiogenesis inhibiting dose of a tetrameric cyclic compound of 4,5-dihydroxynaphtha... | 05/04/2010 |
| 7709537 | Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials This invention relates to drinks and foods having osteogenetic function, each of which comprises as an active ingredient an effective amount of a culture of a propionic acid bacterium and/or a lactic acid bacterium, said culture containing 2-amino-3-carboxy-1,4-naph... | 05/04/2010 |
| 7674830 | Formulation of a mixture of free-B-ring flavonoids and flavans as a therapeutic agent The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways... | 03/09/2010 |
| 7427418 | Phloridzin-rich phenolic fraction and use thereof as a cosmetic, dietary or nutraceutical agent A phenolic fraction of fruit obtained from the Rosaceae family and also to the process for the specific extraction of this fraction. The phenolic fraction is rich in dihydrochalcones (phloridzin and phloretin) and may be used as a cosmetic, dietary, or nutraceutical... | 09/23/2008 |
| 7371895 | Salt forms of poorly soluble probucol esters and ethers Organic amine salts of compounds of the formula: and their pharmaceutically acceptable salts, and uses in medical therapy are provided. ... | 05/13/2008 |
| 7341744 | Method of treating secretory diarrhea with enteric formulations of proanthocyanidin polymer Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer compos... | 03/11/2008 |
| 7338977 | Anti-viral compounds Compounds of formula I wherein at least one R1 is H and the remainder are CH2CO2K; R2 is and L is H are described. The compounds are us... | 03/04/2008 |
| 7323195 | Enteric formulations of proanthocyanidin polymer antidiarrheal compositions Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer compos... | 01/29/2008 |
| 7318930 | Control methods for boring bark beetles A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which... | 01/15/2008 |
| 7288680 | Benzotropolone derivatives and modulation of inflammatory response The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective ant... | 10/30/2007 |
| 7285298 | Use of a dihydrochalcone-rich phenolic fraction in a cosmetic treatment The use of a dihydrochalcone-rich polyphenolic fraction in the cosmetic treatment of mammals in order to limit the weight, to improve the aesthetic appearance of the body, and to treat certain non-pathological forms of obesity. The use of a dietary or nutraceutical ... | 10/23/2007 |
| 7273890 | ST104P, an anti-angiogenic agent The anti-angiogenic functions of a polysulfated, cyclic compound, ST104P, were investigated. ST104P exhibited excellent water solubility and low cytotoxicity to endothelial cells. ST104P potently inhibited the secretion of matrix metalloproteinase (MMPs) by endothel... | 09/25/2007 |
| 7226610 | Compositions and methods for the treatment and prevention of disease in plants Non-toxic, naturally derived and economical compositions for treating and preventing bacterial or fungal disease in plants, especially citrus canker, wherein such compositions include various combinations of d-limonene, wax and monohydric alcohol are provided. Metho... | 06/05/2007 |
| 7220747 | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer This invention provides methods for treating cellular blood components and other cells containing mitochondria to improve vital qualities of the cells by contacting the cells with a mitochondrial enhancer to the cells. Mitochondrial enhancers prevent damage to and r... | 05/22/2007 |
| 7199161 | Substituted bicylo[3.3.1]nonan-2,4,9-triones as pharmaceutical active ingredients The invention relates to the use of substituted bicyclo[3.3.1]nonan-2,4,9-triones, especially clusianon and clusianon derivatives, as pharmaceutical active ingredients or medicamentous active ingredients, especially for producing medicaments for the prophylactic and... | 04/03/2007 |
| 7192612 | Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of therapeutically effective amount of catechins, a group of polyphenols found in green tea, and Capsicum extra... | 03/20/2007 |
| 7135502 | Colchinol derivatives as vascular damaging agents The invention relates to the use of compounds of formula (I): wherein X is —C(O)—, —C(S)—, —C═NOH, or —CH(R7)— wherein R7 is hydrogen, hydroxy, C1-7alkoxy, —OR8 or —NR8R9 (wherein ... | 11/14/2006 |
| 7135501 | Clusianon isomers and use thereof The invention relates to a clusianon isomer and to the use thereof, in particular as a pharmaceutical or medical active ingredient, in particular for producing medicaments for the prophylactic and/or therapeutic (curative) treatment of tumor or cancer diseases as we... | 11/14/2006 |
| 7105705 | Hyperforin derivatives, the use thereof and formulations containing them The use of the reduction products of hyperforin and adhyperforin, pharmaceutically acceptable salts or esters thereof, in the pharmaceutical and/or nutritional field, in particular in the treatment of depression and Alzheimer's disease. ... | 09/12/2006 |
| 7087790 | Benzotropolone derivatives and modulation of inflammatory response The present invention provides novel benzotropolone derivatives represented by the general formula: including neotheaflavate B and EGCGCa. The benzotropolone derivatives of the present invention are effective ant... | 08/08/2006 |
| 7057078 | Hyperforin halogenated derivatives, the use thereof and formulations containing them Hyperforin and adhyperforin halogenated derivatives of general formula (I) in which X, R and R1 have the meanings as defined in the disclosure, the process for the preparation thereof and the use thereof in the pharmaceutical and/or nutritional field, in ... | 06/06/2006 |
| 7049110 | Inactivation of West Nile virus and malaria using photosensitizers Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic a... | 05/23/2006 |
| 7041322 | Phloridzin-rich phenolic fraction and use thereof as a cosmetic, dietary or nutraceutical agent A phenolic fraction of fruit obtained from the Rosaceae family and also to the process for the specific extraction of this fraction. The phenolic fraction is rich in dihydrochalcones (phloridzin and phloretin) and may be used as a cosmetic, dietary, or nutraceutical... | 05/09/2006 |
| RE39061 | Pharmaceutical formulations comprising labdanes for the treatment of tumors or leukemias The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-e... | 04/11/2006 |
| 6989162 | Hepatoprotective agent of plant origin and a process thereof A process of isolation of pure Acteoside of high hepatoprotection from plant Colerbrookea oppositifolia, said process comprising steps of drying aerial parts of the plant, grounding the dried parts into powder, percolating the powder with water or ethanol for... | 01/24/2006 |
| 6967030 | Formulation for insulin and glucose control The formulation includes a combination of a chalcone, specifically, methylhydroxychalcone polymer, in the amount of 6 mg to 24 mg, and chromium, in the amount of 500 mcg to 2000 mcg. The formulation also includes a plurality of vitamins and nutrients, vitamins B | 11/22/2005 |
| 6964784 | METHOD OF PREPARATION AND COMPOSITION OF A WATER SOLUBLE EXTRACT OF THE BIOACTIVE COMPONENT OF THE PLANT SPECIES UNCARIA FOR ENHANCING IMMUNE, ANTI-INFLAMMATORY, ANTI-TUMOR AND DNA REPAIR PROCESSES OF WARM BLOODED ANIMALS A method for isolating the bioactive component of the water-soluble extract of Uncaria tomentosa known as C-MED-100®, comprising (i) precipitating the spray drying carrier from C-MED-100®; (ii) using the resulting C-MED-100® to obtain a spotting mixture fo... | 11/15/2005 |
| 6881756 | Method for treating skin disorders The present invention relates to a method for reducing inflammation in the skin and/or treating inflammatory skin disorders, pain, or pruritis by topically applying a composition comprising totarol or a pharmaceutically-acceptable ester thereof. ... | 04/19/2005 |
| 6855353 | Method for producing antioxidant and prevention of cancer A pharmaceutical composition for prevention and treatment of cancer, cardiovascular disease and antioxidation contains resveratol. The new method of process for producing resveratol is extracted resveratol from oil residue and stems of peanuts or stems of other chea... | 02/15/2005 |
| 6855341 | Anti-viral compositions and methods of making and using the anti-viral compositions Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involvi... | 02/15/2005 |
| 6838583 | Non-halogenated naphthol compounds, antimicrobial compositions containing the same, and the methods of using the same An antimicrobial compound, composition containing such compound, and method of use of the same for reducing the presence of microorganism on a substrate or in a fluid environment comprising an antimicrobial effective carrier and one or more essential antimicrobial c... | 01/04/2005 |
| 6838584 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 01/04/2005 |
| 6824797 | Method for extracting, fractionating and purifying polyphenolic compounds originating from fresh plant sorting deviations using a high adsorption and elution performance resin This invention relates to a method for extracting, fractionating and purifying polyphenolic compounds originating from plants, wherein the purification is performed by adsorption on an adsorbing styrene-divinyl benzene resin, followed by the elution of the polypheno... | 11/30/2004 |
| 6774145 | Material separated from Ecklonia cava, method for extracting and purifying the same, and use thereof as antioxidants Disclosed are novel materials separated from Ecklonia cava, a method for extracting and purifying the same, and the use thereof for antioxidants. The method comprises extracting antioxidative ingredients from powdered Ecklonia cava one or more times wi... | 08/10/2004 |
| 6759064 | Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of catechins and vanilloids. Compositions of catechins include but not limited to, epigallocatechin gallate (EGCg), ep... | 07/06/2004 |
| 6730294 | Method of forming a water soluble biocidal film on a solid surface A method of forming a water soluble biocidal film on a solid household, food preparation, or medical surface, which protects the solid surface against reinfection by microorganisms, includes providing a liquid biocidal composition comprised of, based on total weight... | 05/04/2004 |
| 6696484 | Method and compositions for regulation of 5-alpha reductase activity Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5-reductase inhibitor, such as natural and synthetic flavanoids, catechols, curcumin-related substances, quinones, catech... | 02/24/2004 |
| 6686371 | Non-steroidal, tetracylic compounds for estrogen-related treatments The invention provides non-steroidal estrogenic compounds with estrogenic and anti-estrogenic compounds effects for treatment of estrogen-deficiency related disorders, which compounds are having formula (I) wherein, one of Ra or Rb i... | 02/03/2004 |
