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"That the automobile has practically reached the limit of its development is suggested by the fact that during the past year no improvements of a radical nature have been introduced."
Scientific American ; Jan. 2 edition, 1909
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| Number | Title | Issue Date |
| 7999010 | Indene derivatives as pharmaceutical agents Compounds of formula (Ia): wherein R1, R2, R3, R4a, R4b, R5 and R6 are defined herein, as well as other indene derivative... | 08/16/2011 |
| 7902261 | Medicinal compositions for preventing or treating viral myocarditis The present invention aims at providing a pharmaceutical composition for the prophylaxis or treatment, irrespective of the kind of virus, of viral myocarditis or viral diseases induced by viral myocarditis, by the treatment or prevention of the onset of cytotoxicity... | 03/08/2011 |
| 7745496 | Process for preparing halogenoalkylnitrates A process for preparing a compound of formula (I) X-(CH2)n-ONO2 (I) wherein: X is a halogen atom selected from Cl, Br, I; n is an integer from 3 to 6; said process compris... | 06/29/2010 |
| 7345096 | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms The present invention relates to the use of compounds and composition of compounds that modulate norepinephrine levels for the prevention and treatment of vasomotor symptoms, such as hot flush, caused by, inter alia, thermoregulatory dysfunctions. ... | 03/18/2008 |
| 7334538 | Topical medicants for aquatic animals A topical medicant for fishes, amphibians, reptiles, and aquatic macroinvertebrates applied in a site-specific manner for the localized treatment of skin wounds, lesions and diseases. The medicant comprises a hydrophilic carrier with an antimicrobial therapeutant fo... | 02/26/2008 |
| 7226610 | Compositions and methods for the treatment and prevention of disease in plants Non-toxic, naturally derived and economical compositions for treating and preventing bacterial or fungal disease in plants, especially citrus canker, wherein such compositions include various combinations of d-limonene, wax and monohydric alcohol are provided. Metho... | 06/05/2007 |
| 7179489 | Process for preparing a pharmaceutical composition containing an active ingredient and a micronised carrier/diluent The invention relates to a stable pharmaceutical composition useful in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD) and a novel micronization process for manufacturing a stable formulation for formo... | 02/20/2007 |
| 7176244 | Use of 2-nitropropanol, 2-nitroethane, and 2-nitroethanol for control of microbial pathogens The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of 2-nitropropano... | 02/13/2007 |
| 7135600 | Phenethanolamine derivatives for treatment of respiratory diseases The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases. ... | 11/14/2006 |
| 7041704 | Methods of treating gastrointestinal tract disorders using sodium channel modulators The invention relates to methods of using sodium channel modulators, particularly TTX-R sodium channel modulators and/or activity dependent sodium channel modulators to treat a gastrointestinal tract disorders, particularly inflammatory bowel disorders and irritable... | 05/09/2006 |
| 7030162 | Treatment of migraine headache The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the... | 04/18/2006 |
| 7008545 | Synergistic biocidal mixtures Synergistic mixtures of biocides and their use to control the growth of microorganisms in aqueous systems are disclosed. The method of using the synergistic mixtures entails adding an effective amount of a nitrogenous compound activated by an oxidant and at least on... | 03/07/2006 |
| 6946486 | Quaternary ammonium compounds The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis. ... | 09/20/2005 |
| 6919092 | Method for the management of incontinence A composition and a dosage form are disclosed comprising oxybutynin alone/or accompanied by another drug indicated for therapy. A method is disclosed for administering oxybutynin alone/or accompanied by a different drug or for administering oxybutynin and a differen... | 07/19/2005 |
| 6855341 | Anti-viral compositions and methods of making and using the anti-viral compositions Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involvi... | 02/15/2005 |
| 6774111 | Carbohydrate system and a method for providing nutrition to a diabetic The two carbohydrate mixture of this invention utilizes a source of fructose in combination with at least one readily digestible glucose polymer source. The addition of the fructose significantly decreases the glycemic response when compared to the digestible glucos... | 08/10/2004 |
| 6664297 | Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol The inhibition of the formation and development of amyloidoses, as well as the dissolution of amyloidoses in organisms is claimed. Methods for the diagnosis of amyloidoses using aromatic and heteroaromatic compounds having at least one electron-withdrawin... | 12/16/2003 |
| 6646011 | Insect repellant compositions The present invention relates to insect repellant compositions containing, based upon the total weight of the composition, from about 6 to about 30 percent by weight of insect repellant active material having functionality selected from ester, amide, uret... | 11/11/2003 |
| 6641800 | Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer soluble in the liquefied hydrofluoroalkane which is selected fr... | 11/04/2003 |
| 6613313 | Aniline compound-containing hair dye composition and method of dyeing hair A hair dye composition containing at least one of the following compounds: ##STR1## or analogues thereof; and a method for dyeing hair which comprises a step of applying to the hair the hair dye composition is used. The dye composition of the invention ex... | 09/02/2003 |
| 6607735 | Method for reducing the appearance of dark circles under the eyes The invention relates to a method for the treatment of the skin around the eyes of a mammal, in particular a method for reducing the puffiness of and the appearance of dark circles on the skin under the eyes. The method comprises topically applying to the... | 08/19/2003 |
| 6559181 | Antiestrogens, process for their protection and their pharmaceutical use This invention relates to new antiestrogens of the general formula ##STR1## in which the substituents have the meanings that are explained in more detail in the description. The new compounds are a) pure antiestrogens or b) antiestrogens with partial estr... | 05/06/2003 |
| 6482846 | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs Nonsteroidal antiinflammatory drugs which have been substituted with a nitrogen monoxide group; compositions comprising (i) a nonsteroidal antiinflammatory drug, which can optionally be substituted with a nitrogen monoxide group and (ii) a compound that d... | 11/19/2002 |
| 6444230 | Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid, c) from 0.001% to 35% by weight of hydrogen peroxide, d) from 0.0001... | 09/03/2002 |
| 6433021 | Indane compounds and their pharmaceutical use Indane compounds of general formulae (1) to (4) and their pharmaceutical use, particularly to achieve mast cell stabilising activity and/or anti-inflammatory activity are described. In these formulae R1 to R7 may be selected from: H,... | 08/13/2002 |
| 6432390 | Low VOC methyl acetate hair sprays Embodiments relate to reduced VOC hair spray compositions. One composition includes a concentrate and propellant. The concentrate includes 25-45 weight percent alcohol, 30-50 weight percent methyl acetate, 5-15 weight percent resin, 0.2-1.3 weight percent... | 08/13/2002 |
| 6414033 | Drug dosage form based on the teorell-meyer gradient A method for delivery of pharmaceutically effective amounts of drugs and therapeutic ions is disclosed. More particularly, a method of formulating a dosage form that will move drugs, pro-drugs or therapeutic ions in either cationic or anionic form between... | 07/02/2002 |
| 6410597 | Hydroxyalkyl amide analogs of ceramide The present invention provides methods for treating disease conditions associated with abnormal cellular proliferation, inflammation and viral infection or proliferation by the administration of ceramic analogs. The ceramic analogs appear to be specific f... | 06/25/2002 |
| 6369115 | Stabilized powder formulations A dry powder formulation for treatment of pulmonary conditions, via inhalation, includes an effective amount of formoterol or a salt or solvate thereof, in a dry powder form, an effective amount of fluticasone, in a dry powder form, and an excipient. A me... | 04/09/2002 |
| 6358537 | Deodorant and antimicrobial dispersions A deodorant and antimicrobial dispersion is formed of a deodorant and antimicrobial component, a binder resin and an aqueous or oily liquid medium. The deodorant and antimicrobial component comprises an oxide or hydroxide of an alkaline earth metal, hydra... | 03/19/2002 |
| 6337337 | Methods for treating disorders responsive to DHFR-inhibition A method for treating disorders responsive to DHFR inhibition is disclosed, wherein the disorders may include neoplastic diseases, rheumatoid arthritis, restenosis, multiple sclerosis, lupus, infections, and ectopic pregnancy. The inventive method compris... | 01/08/2002 |
| 6333350 | Use of nitric oxide donors and/or substrates or nitric oxide inhibitors for regulating cervical dilatation and extensibility The invention describes the regulation of cervical dilatation and extensibility by the use of nitric oxide donors and/or substrates or nitric oxide inhibitors. There can be used either (a) at least one nitric oxide donor and/or substrate for manufacture of a ... | 12/25/2001 |
| 6323243 | Tyrosine-derived compounds as calcium channel antagonists The present invention provides compounds that block calcium channels and have the Formula I: ##STR1## and pharmaceutically acceptable salts, esters, and pro-drugs thereof, wherein R1 and R2 are independently H, phenylcyclopentylcarbo... | 11/27/2001 |
| 6323234 | Methods to treat gastrointestinal lesions and to reduce drug-induced gastrointestinal or renal toxicity Nonsteroidal antiinflammatory drugs which have been substituted with a nitrogen monoxide group; composition comprising (i) a nonsteroidal antiinflammatory drug, which can optionally be substituted with a nitrogen monoxide group and (ii) a compound that di... | 11/27/2001 |
| 6310060 | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of the formula ##STR1## where R1, R2, R3, R4, R5, and R6 are hydrogen or substituent groups such as alkyl, and where R | 10/30/2001 |
| 6303656 | Composition comprising urea, and its uses in the field of cosmetics and/or dermatology A composition comprising urea and an N-substituted aminosulfonic acid. The composition may be used for the care, treatment and/or protection of human skin, mucous membranes and/or keratin fibers, in particular for moisturizing the skin and for the treatme... | 10/16/2001 |
| 6291533 | Dietary supplements for each specific blood type Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.... | 09/18/2001 |
| 6271264 | Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective amount of a spirobicyclic ammonium moiety-containing polyme... | 08/07/2001 |
| 6217914 | Ascorbic acid composition and method for treatment of aging or damaged skin An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which has generally been pretreated by being dissolved under relat... | 04/17/2001 |
| 6168808 | Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid, c) from 0.001% to 35% by weight of hydrogen peroxide, d) from 0.0001... | 01/02/2001 |
