An armor with rollers is provided that enables a user to move in all positions by rolling on a hard and smooth surface while constantly varying his bearing points on the ground.
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| Number | Title | Issue Date |
| 7576135 | Diamine derivatives A compound represented by formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4 (1) [wherein R1 and R2 are hydrogen atoms or the like; Q1... | 08/18/2009 |
| 7388112 | Immunomodulation with novel pharmaceutical compositions The synthesis and use of a novel class of tumor necrosis factor (TNFα) inhibitors and immunomodulators are provided. Examples are those having the structures: wherein a, b and c are integers from 0 to 12, X equals NH or CH... | 06/17/2008 |
| 7374770 | Topical composition for follicular delivery of an ornithine decarboxylase inhibitor Polyethylene glycol ethers of alkyl alcohols having the general formula CH3(CH2)xCH2(OCH2CH2)nOH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 and steareth-100 are preferred), po... | 05/20/2008 |
| 7307071 | RAF-MEK-ERK pathway inhibitors to treat cancer Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia, and which cancer is preferably resistant to the inhibition of the Bc... | 12/11/2007 |
| 7279502 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions... | 10/09/2007 |
| 7276538 | Composition and a method for treating hair loss The use of the polyamine known as spermidine, i.e., N-(3-aminopropyl) tetraminethylenediamine, as an active principle in the preparation of a composition for pharmaceutical or dietetic use in man for combating hair loss is disclosed. ... | 10/02/2007 |
| 7232846 | Amines as anti-alcoholism agents The oral administration to genetically alcoholic rats (from the strain UChB of the University of Chile) of a compound selected from endogenic polyamines (putrescine, spermidine, spermine), 1,3-propanediamine, their pharmaceutically acceptable salts and solvates, and... | 06/19/2007 |
| 7202280 | Methods for the treatment and prevention of pancreatitis and for induction of liver regeneration Novel methods for treating and preventing acute and/or chronic pancreatitis are described. Additionally, novel methods for inducing liver regeneration are described. The methods may comprise administering to a patient an effective amount of a metabolically stable an... | 04/10/2007 |
| 7094808 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment Polyamines having the formula: or a salt thereof with a pharmaceutically acceptable acid wherein: R1-R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having ... | 08/22/2006 |
| 7087648 | Methods for modulating macrophage proliferation using polyamine analogs Methods for modulating macrophage proliferation in an individual afflicted with or at risk for a macrophage-associated disease are provided. The methods employ a polyamine analog, or salt or protected derivative thereof. Macrophage proliferation has been implicated ... | 08/08/2006 |
| 7045550 | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more polyamine effectors formulated fo... | 05/16/2006 |
| 7001925 | Compounds and method for enhancing the efficacy of anti-cancer drugs Polyamine compounds, method of synthesis and method of use for anti-cancer purposes, and for enhancing the activity of existing anti-cancer drugs are provided. This disclosure has identified certain polyamine motifs that can be attached to toxic agents to facilitate... | 02/21/2006 |
| 6951890 | Preventing and/or treating cardiovascular disease and/or associated heart failure Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such a... | 10/04/2005 |
| 6919483 | Immunomodulation with novel pharmaceutical compositions The synthesis and use of a novel class of tumor necrosis factor (TNFα) inhibitors and immunomodulators are provided. These compounds have pharmacological applications as well as uses in assays relating to TNFα and other involved cytokines. As pharmaceuticals, thes... | 07/19/2005 |
| 6869944 | Method for treating a patient with neoplasia by treatment with a platinum coordination complex This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an antineoplastic platinum coordination complex. ... | 03/22/2005 |
| 6716882 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transfor... | 04/06/2004 |
| 6685953 | External preparation compositions The present invention relates to a dermatologic preparation containing a diamide derivative represented by the following formula (1): ##STR1## (wherein, R1 represents a linear or branched hydrocarbon group having 1 to 22 carbon atoms which may ... | 02/03/2004 |
| 6656912 | Methods to treat 댑-antitrypsin deficiency Inhibitors of glucosidase, especially those related to castanospermine, are effective in preventing or ameliorating conditions such as liver damage and emphysema that are present in individuals who produce a mutant form of antitrypsin, 댑-ATZ. Also ... | 12/02/2003 |
| 6605645 | Linear polyamine compounds and polyamine-based anti-tumor agents Nobel polyamine compounds and polyamine compounds having carcinostatic action are provided. There are also provided anticancer agents containing as active ingredient at least one of polyamine compounds represented by the following Formula (I) or (III) and... | 08/12/2003 |
| 6541038 | Method for treating wood with a metal-containing treating agent and wood treated thereby A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion and oxidizing and/or macromolecularizing of the lignin and/... | 04/01/2003 |
| 6482833 | Immunotherapeutic anti-cancer pharmaceutical compositions There is disclosed a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having a mechanism of action as spermine antagonists. The present pharmaceutical compositions are able to inhibit the inhibitory e... | 11/19/2002 |
| 6464764 | Protective agents for wood Solvent-free coating materials and treating agents used as water-based wood or material protective agents containing emulsifiable binding agents, quaternary ammonium compounds and optional additional active agents. The wood or material protective agents a... | 10/15/2002 |
| 6444230 | Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid, c) from 0.001% to 35% by weight of hydrogen peroxide, d) from 0.0001... | 09/03/2002 |
| 6399106 | Method for maintaining freshness of cut flower A method for maintaining the freshness of a cut flower is disclosed. The method comprises the step of causing a flowering plant to imbibe an aqueous solution of a composition for maintaining the freshness of flower which comprises a mixture or a reaction ... | 06/04/2002 |
| 6399663 | Highly packed polycationic ammonium, sulfonium and phosphonium lipids The present invention discloses highly packed polycationic ammonium, sulfonium and phosphonium lipid compounds useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-depende... | 06/04/2002 |
| 6342534 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment Polyamines having the formula: ##STR1## or a salt thereof with a pharmaceutically acceptable acid wherein: R1 -R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having an alkyl chain interrupted by at... | 01/29/2002 |
| 6255277 | Localized use of nitric oxide-adducts to prevent internal tissue damage A method for preventing adverse effects associated with the use of a medical device in a patient by introducing into the patient a device of which at least a portion includes a prophylactic or therapeutic amount of a nitric oxide adduct. The nitric oxide ... | 07/03/2001 |
| 6248356 | Immunotherapeutic anti-cancer pharmaceutical compositions There is disclosed a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having a mechanism of action as spermine antagonists. The present pharmaceutical compositions are able to inhibit the inhibitory e... | 06/19/2001 |
| 6217914 | Ascorbic acid composition and method for treatment of aging or damaged skin An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which has generally been pretreated by being dissolved under relat... | 04/17/2001 |
| 6197822 | Neuropeptide antagonists The compound ##STR1## is a neuropeptide Y antagonist and is effective in treating feeding disorders, cardiovascular diseases and other physiological disorders.... | 03/06/2001 |
| 6184254 | Methods of identifying modulators of perivascular sensory nerve Ca2+ receptors Methods of identifying compounds that relax or stimulate arterial tension through their action on perivascular sensory nerve calcium receptors are described. Compounds identified through such methods are useful for the treatment of hypertension, hypotensi... | 02/06/2001 |
| 6184232 | Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment Polyamines having the formula: ##STR1## or a salt thereof with a pharmaceutically acceptable acid wherein: R1 -R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having an alkyl chain interrupted ... | 02/06/2001 |
| 6168808 | Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid, c) from 0.001% to 35% by weight of hydrogen peroxide, d) from 0.0001... | 01/02/2001 |
| 6139879 | Fungicidal and bactericidal compositions for plants containing compounds in the form of heavy metal chelates The present invention relates to heavy metal chelate compositions, which are used as fungicides and bactericides, and methods of using the compositions. In particular, the present invention relates to a chelate, that is an EDDHA (copper-ethylenediamine-di... | 10/31/2000 |
| 6060471 | Reduction of hair growth Mammalian hair growth is reduced by applying to the skin an inhibitor of hypusine biosynthetic pathway.... | 05/09/2000 |
| 6015828 | Chemical modification of chloride channels as a treatment for cystic fibrosis and other diseases This invention relates generally to medical treatment methods. Specifically, the invention relates to methodology for the correction of defective chloride transport by activation of chloride channels of the lung and other epithelia using genetic or chemic... | 01/18/2000 |
| 6011066 | Method for treating septic shock A method for the treating septic shock in a patient comprises administering to the patient a therapeutically-effective amount of a composition comprising a compound having the formula (I): ##STR1## wherein R1 is hydrogen, hydroxyl, carboxy... | 01/04/2000 |
| 6008188 | Cytokine potentiator and pharmaceutical formulation for cytokine administration A cytokine activity enhancer comprising an ethanolamine derivative of the following general formula (I) or a salt thereof, or comprising it along with cytokine or a cytokine production promoter; and also a medicine for diseases with lowered cytokine activ... | 12/28/1999 |
| 5945432 | Thrombolytic agents and thienopyridine derivatives in acute stroke Methods and products are provided for treating thromboembolic stroke. A method involves the administration of a thienopyridine derivative in combination with a thrombolytic agent to a patient suffering from thromboembolic stroke. Preferably the thienopyri... | 08/31/1999 |
| 5939458 | Reduction of hair growth Mammalian hair growth is reduced by applying an inhibitor of aminoacyl-tRNA synthetase to the skin.... | 08/17/1999 |