Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 7872050 | Stabilized compositions of volatile alkylating agents and methods of using thereof A composition and method for treatment of cancer. The composition for treating a skin disorder, comprising: a Nitrogen Mustard or an HX salt of the Nitrogen Mustard, wherein the Nitrogen Mustard or the HX salt of the Nitrogen Mustard is in a non-aqueous vehicle or c... | 01/18/2011 |
| 7838564 | Stabilized compositions of volatile alkylating agents and methods of using thereof A composition and method for treatment of cancer. The composition for treating a skin disorder, comprising: a Nitrogen Mustard or an HX salt of the Nitrogen Mustard, wherein the Nitrogen Mustard or the HX salt of the Nitrogen Mustard is in a non-aqueous vehicle or c... | 11/23/2010 |
| 7307071 | RAF-MEK-ERK pathway inhibitors to treat cancer Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia, and which cancer is preferably resistant to the inhibition of the Bc... | 12/11/2007 |
| 7201854 | Active compound combinations for protecting animal hides and leather The present application relates to the use of active compound combinations containing phenolic active compounds and fungicidal active compounds for preserving animal hides and leather. ... | 04/10/2007 |
| 7202225 | Therapeutic delivery compositions and methods of use thereof The present invention relates to compositions and methods for delivery of antisense oligonucleotides or other nucleic acid sequences. The present invention comprises a delivery composition comprising an administerable admixture of an effective amount of a nucleic ac... | 04/10/2007 |
| 7074459 | Method for preserving wood A method for preserving wood which comprises contacting the wood with a complex of a cationic monomeric or polymeric biocide and an anionic monomeric or polymeric biocide. Insoluble complexes may solubilized in water in the form of an emulsion or microemulsion by ad... | 07/11/2006 |
| 6929685 | Alkylamine derivatives as antifouling agents The invention relates to methods for preventing the attachment of aquatic organisms to surfaces that are submerged for extension periods of time in water. More particularly, this invention relates to the protection of submerged surfaces with alkylamine derivatives a... | 08/16/2005 |
| 6809120 | Composition containing propargylamine for enhancing cancer therapy Antineoplastic drug modulators are described. The specific modulators referred to are propargylamines which can enhance the cytotoxic effects of antineoplastic drugs on cancer cells while protecting normal cells from damage. The propargylamine modulators can be used... | 10/26/2004 |
| 6617157 | Methods and compositions for the selective modification of nucleic acids Methods and compositions for selectively modifying nucleic acid molecules in biological compositions, including contacting the composition with an inactivating agent having the formula: ##STR1## where each of R1, R2, R3, R... | 09/09/2003 |
| 6569905 | Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia and atherosclerosis. Combinations disclosed include an cholesteryl ester transfer... | 05/27/2003 |
| 6562872 | Emulsion of perfluoroorganic compounds for medical purposes, a process for the preparation thereof and methods for treating and preventing diseases with the use thereof An emulsion of perfluoroorganic compounds (PFOC) comprises a rapidly eliminable perfluorocarbon (PFC) and a slowly eliminable perfluorinated cyclic tertiary amine, perfluoro-N-4-(methylcyclohexyl)-piperidine and additionally comprises not less then three ... | 05/13/2003 |
| 6444230 | Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid, c) from 0.001% to 35% by weight of hydrogen peroxide, d) from 0.0001... | 09/03/2002 |
| 6375727 | Amine oxide/iodine containing blends for wood preservation The present invention provides a composition comprising an amine oxide and an iodine containing biocide. Another embodiment of the present invention is a method for preserving and/or waterproofing a wood substrate by contacting the composition with the wo... | 04/23/2002 |
| 6315756 | Tumescent solution Compositions of perfluorocarbons and methods of using these compositions for subcutaneous fat removal. A version of the composition also contains local anesthetic and/or vasoconstrictors. The composition is in association with a pharmacuetical carrier. Th... | 11/13/2001 |
| 6168808 | Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid, c) from 0.001% to 35% by weight of hydrogen peroxide, d) from 0.0001... | 01/02/2001 |
| 6140346 | Treatment of cancer with thalidomide alone or in combination with other anti-cancer agents A method is provided for the treatment of neoplastic diseases in a mammal which comprises administering to said mammal a therapeutically effective amount of thalidomide. The method also uses a combination of thalidomide with other anti-neoplastic agents. ... | 10/31/2000 |
| 6103768 | Fatty acid based compositions and methods for the control of plant infections and pests The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination treatments whereby fatty acids are used to enhance or aug... | 08/15/2000 |
| 6090832 | Process for making antimicrobial agents in aqueous dispersion form containing 2-(4-thiazolyl)-benzimidazole alone or in combination with 1,2-dibromo-2,4-dicyanobutane Aqueous dispersions of 2-(4-thiazolyl)-benzimidazole (TBZ), alone or in combination with 1,2-dibromo-2,4-dicyanobutane (DBDCB), and processes for making the same, are disclosed. These processes generally comprise mixing a xanthan gum with water, adding TB... | 07/18/2000 |
| 6075044 | Heterocyclic derivatives as inhibitors of purine salvage phosphoribosyltransferases The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.... | 06/13/2000 |
| 6046234 | Formulations and methods of reducing toxicity of antineoplastic agents This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineopl... | 04/04/2000 |
| 6004958 | Compounds and methods for therapeutic intervention in preventing diabetic complications and procedures for assessing a diabetic's risk of developing complications and determining the efficacy of therapeutic intervention The present invention is based on the discovery of a metabolic pathway in which a specific kinase converts fructose-lysine into fructose-lysine-3-phosphate in an ATP dependent reaction. Fructose-lysine-3-phosphate (FL3P) is then broken down to form free ... | 12/21/1999 |
| 5985934 | Synergistic antimicrobial composition of 2,4,4'-trichloro-2'-hydroxydiphenyl ether and 1,2-dibromo-2,4-dicyanobutane Synergistic antimicrobial combinations consisting essentially of comprising 2,4,4'-trichloro-2'-hydroxydiphenyl ether and 1,2-dibromo-2,4-dicyanobutane are disclosed. Methods for inhibiting microbial growth using these synergistic antimicrobial combinatio... | 11/16/1999 |
| 5973000 | Hair revitalization tonic composition containing a lipid derivative and use thereof The invention relates to a hair revitalizing tonic composition containing, as an active ingredient, at least one lipid derivative of the general formula ##STR1## wherein R1, R2, R3, R4 and Y are as defined ... | 10/26/1999 |
| 5919816 | Formulations and methods of reducing toxicity of antineoplastic agents This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineopl... | 07/06/1999 |
| 5508311 | Aliphatic propargylamines as selective MAO-B inhibitors and as neuroprotective agents The invention relates to a series of propargylamines, their salts and pharmaceutical compositions containing a compound of formula (III) wherein R1, R3 and R4 are the same or different and represent hydrogen or a straight ... | 04/16/1996 |
| 5468759 | Synergistic microbicidal combinations containing 4,5-dichloro-2-octyl-3-isothiazolone and certain commercial biocides Synergistic microbicidal compositions are disclosed, comprising 4,5-dichloro-2-octyl-3-isothiazolone and 5 bromo-5-nitro-1,3,dioxane for more effective, and broader control of microorganisms in various systems.... | 11/21/1995 |
| 5389300 | Agent for protecting sawn timber The present invention relates to an agent or concentrate for protecting sawn timber against wood-discolouring fungi, containing a fungicide on phenol basis and a fungicide on organo-iodine basis, optionally fungicides and insecticides, dissolved in an org... | 02/14/1995 |
| 5374624 | Fluorocarbon blood substitute The present invention relates to fluorochemical blood substitutes used for preserving mammalian tissue having lysophosphatidyl compounds in non-toxic concentrations. More specifically, the invention relates to aqueous fluorochemical emulsions of a fluoroc... | 12/20/1994 |
| 5244924 | Diluent for perfluorocarbons employed for retinal unfolding (unfolding PFCL) and method of treatment A diluent for perfluorocarbons used for retinal unfolding (unfolding PFCL), consisting of a perfluorocarbon (diluent PFCL), which has a low viscosity and is volatile at room temperature, with a boiling point between body temperature (about 38° C.) and 10... | 09/14/1993 |
| 5169868 | Aliphatic propargylamines as specific MAO-B inhibitors A component having the following formula I: ##STR1## wherein X represents an integer ranging from 1 to 2 or 7 to 13; Y represents an integer ranging from 0 to 5; Z represents an integer ranging from 0 to 5; R1, R2 and R3 are th... | 12/08/1992 |
| 5149319 | Methods for providing localized therapeutic heat to biological tissues and fluids Gas, gaseous precursors and prefluorocarbons are presented as novel potentiators for ultrasonic hyperthermia. The gas, gaseous precursors and perfluorocarbons which may be administered into the vasculature, interstitially or into any body cavity are desig... | 09/22/1992 |
| 5077314 | Agricultural gel-forming compositions A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method, the agricultural chemicals are applied to the soil dispersed... | 12/31/1991 |
| 5061484 | Perfluorochemical emulsion with stabilized vesicles A stable perfluorochemical emulsion is provided which comprises perfluorochemical particles in stabilized vesicles. The vesicles comprise a biocompatible polymer formed by coating the perfluorochemical particles with one or more phospholipid monomer(s) an... | 10/29/1991 |
| 4942179 | Single-phase composition containing a perfluorinated oil and one or more surfactant(s), useful as an excipient for cosmetic and dermatologic formulations, as well as for biomedical applications A single-phase, either isotropic or anisotropic formulation is disclosed, which contains perfluorinated oil and one or more surfactant(s), is useful as an excipient for cosmetic and dermatologic formulations and is characterized in that at least one surfa... | 07/17/1990 |
| 4935447 | Agricultural gel-forming compositions A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method, the agricultural chemicals are applied to the soil dispersed... | 06/19/1990 |
| 4851448 | Gem-dihalo-1,8-diamino-4-aza-octanes Gem-dihalo-1,8-diamino-4-aza-octane derivatives useful as antiproliferative or antitumor agents.... | 07/25/1989 |
| 4769241 | Apparatus and process for oxygenation of liquid state dissolved oxygen-carrying formulation Perfluorocarbon emulsion formulations are oxygenated prior to use by means of a portable oxygenation system. The blood substitute is in a closed container or bag. An oxygen-containing gas is introduced into the bag from a separate container. The bag is co... | 09/06/1988 |
| 4661092 | Peritoneal artificial lung A process for the treatment of hypoxia is provided. The process involves the infusion of highly oxygenated perfluoro-chemicals into the peritoneal cavity of a patient, for oxygen transport into the body and carbon dioxide transport out of the body. The ox... | 04/28/1987 |
| 4497829 | Process for preparing perfluorochemical emulsion artificial blood Particles of perfluoro compound with a lipid coating are emulsified by sonification in aqueous medium, wherein the proportion of perfluoro compound in the emulsion is preferably about 30-75% (w/v) and the proportion of lipid is preferably about 7-9% (w/v)... | 02/05/1985 |
| 4418077 | Fluorinated amino-butyric acid and diaminobutane derivatives Fluorinated aminobutyric acid and diaminobutane compounds in vivo are inhibitors of gamma-aminobutyric acid transaminase and have the following formula: ##STR1## wherein: Y represents hydrogen or fluorine; Z represents --CH2 NR1... | 11/29/1983 |
