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"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 7897647 | Releasable polymeric conjugates based on aliphatic biodegradable linkers Activated polymeric bicine derivatives such as as well as conjugates made therewith are disclosed. Methods of making and using the bicine derivatives are also disclosed. ... | 03/01/2011 |
| 7629386 | Compositions containing trialkanolamine alkoxylate buffer The use of compositions containing one or more antimicrobial agents with one or more trialkanolamine alkoxylate buffers to disinfect and/or preserve medical devices is described. Solutions containing one or more antimicrobial agents with one or more trialkanolamine ... | 12/08/2009 |
| 7393825 | Microdose therapy Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve administration of nitric oxide (NO), agents which are able to provid... | 07/01/2008 |
| 7250157 | Dermatological compositions and methods Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds,... | 07/31/2007 |
| 7145039 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 12/05/2006 |
| 7122189 | Releasable polymeric conjugates based on aliphatic biodegradable linkers Activated polymeric bicine derivatives such as as well as conjugates made therewith are disclosed. Methods of making and using the bicine derivatives are also disclosed. ... | 10/17/2006 |
| 7087229 | Releasable polymeric conjugates based on aliphatic biodegradable linkers Activated polymeric bicine derivatives such as, as well as conjugates made therewith are disclosed. Methods of making and using the bicine derivatives are also disclosed. ... | 08/08/2006 |
| 7060731 | Use of amines This application relates to the use of certain amines of formula (I) for combatting and preventing systemic and local complement activation, and in particular to the use of meglumine and derivatives and optionall... | 06/13/2006 |
| 6955804 | Dermatological compositions and methods Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds,... | 10/18/2005 |
| 6946484 | Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype Methods and formulations for inhibiting and preventing a malignant cell phenotype by administering to cells a low dose of a nitric oxide mimetic are provided. ... | 09/20/2005 |
| 6932985 | Azide method and composition for controlling deleterious organisms Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising azide and amine. The azide can be selected from the group consisting of sodium azide... | 08/23/2005 |
| 6818656 | Method and composition for treatment of irritable bowel disease A method and composition for treating irritable bowel syndrome in a subject in need of such treatment, utilizing an amount of a polyamine having the formula: 1) R—NH—(CH2)a—NH—(CH2)b | 11/16/2004 |
| 6685953 | External preparation compositions The present invention relates to a dermatologic preparation containing a diamide derivative represented by the following formula (1): ##STR1## (wherein, R1 represents a linear or branched hydrocarbon group having 1 to 22 carbon atoms which may ... | 02/03/2004 |
| 6673360 | Technique for emulsifying highly saturated hydroisomerized fluids A preferred emulsifier blend includes ethoxylated alcohols containing hydrocarbons of C10-C16 and preferably having on average at least 2.8 ethoxy and/or alcohol groups per chain and a glycerol mono- and/or dioleates, preferably in a ratio of from 9:1 to ... | 01/06/2004 |
| 6664270 | Method and composition for treatment of irritable bowel disease A method and composition for treating irritable bowel syndrome in a subject in need of such treatment, utilizing an amount of a polyamine having the formula:... | 12/16/2003 |
| 6623724 | Dermatological compositions and methods Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various... | 09/23/2003 |
| 6610652 | Microdose therapy Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve administration of nitric oxide (NO), agents which are abl... | 08/26/2003 |
| 6458795 | Method and composition for treatment of irritable bowel disease A method and composition for treating irritable bowel syndrome in a subject in need of such treatment, utilizing an amount of a polyamine having the formula: R--NH--(CH2)a --NH--(CH2)b H--(CH2)c... | 10/01/2002 |
| 6423683 | Microdose therapy Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve administration of nitric oxide (NO), agents which are abl... | 07/23/2002 |
| 6277891 | Nitric oxide inhibits rhinovirus infection Nitric oxide generating compounds or compounds which induce in situ synthesis of nitric oxide can be used to inhibit rhinovirus infection. Nitric oxide has the ability to inhibit both viral replication as well as the synthesis of cytokines, in particular ... | 08/21/2001 |
| 6274630 | Method of inhibiting biosynthesis of EIf5A A method and pharmaceutical composition for inhibiting or preventing the intracellular biosynthesis of EIf5A by the administration to a human or non-human mammal in need thereof an amount of a polyamine analogue or salt thereof sufficient to deplete the s... | 08/14/2001 |
| 6190733 | Alkylated aminoether surfactants This invention provides water-based compositions, particularly coating, ink, and agricultural compositions, manifesting reduced equilibrium and dynamic surface tension by the incorporation of a surface tension reducing amount of certain alkylated aminoeth... | 02/20/2001 |
| 6165975 | Microdose therapy A method of treatment, in an organism, of a vascular condition, comprising administration of at least one agent at a level which enhances NO and which does not appreciably alter normal systemic vascular tone in said organism. At least one agent is an NO d... | 12/26/2000 |
| 6103768 | Fatty acid based compositions and methods for the control of plant infections and pests The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination treatments whereby fatty acids are used to enhance or aug... | 08/15/2000 |
| 6051056 | Alkylated aminoether surfactants This invention provides water-based compositions, particularly coating, ink, and agricultural compositions, manifesting reduced equilibrium and dynamic surface tension by the incorporation of a surface tension reducing amount of certain alkylated aminoeth... | 04/18/2000 |
| 5973000 | Hair revitalization tonic composition containing a lipid derivative and use thereof The invention relates to a hair revitalizing tonic composition containing, as an active ingredient, at least one lipid derivative of the general formula ##STR1## wherein R1, R2, R3, R4 and Y are as defined ... | 10/26/1999 |
| 5906987 | Treatment of male climacteric disorders with nitric oxide synthase substrates and/or donors, in combination with androgens and/or aromatase inhibitors The symptoms of climacterium in male mammals, e.g., hypertension, cardiovascular disease and osteoporosis, are ameliorated by the administration to an afflicted individual one or both of a nitric oxide substrate and/or nitric acid donor, in combination wi... | 05/25/1999 |
| 5902772 | Widely-bridged alcohol polyethoxylates and their use Described are ω,ω -,ω-alkanediylbis(alkylimino)!bis(alkanolpolyethoxylates) in which (i) the alkane group has in the range of 4 to 12 carbon atoms, (ii) the alkyl groups can be the same or different and contain up to about 24 carbon atoms... | 05/11/1999 |
| 5895765 | Method for the detection of an analyte by immunochromatography Disclosed is an improved method for the detection of an analyte in a fluid test sample using a strip of a negatively charged matrix material having a zone containing mobile, labeled binding partner for the analyte and a separate zone for capturing the lab... | 04/20/1999 |
| 5801202 | Amine derivatives for treatment of skin disorders Disclosed is an amine derivative represented by the following formula (1) or an acid addition salt thereof: ##STR1## wherein R1 represents a group ##STR2## a cyclopentyl group, cyclohexyl group, or a cycloheptyl group, R2 i... | 09/01/1998 |
| 5801181 | Amino alcohol substituted cyclic compounds Therapeutic compounds have the formula: (X)j--(core moiety), J being an integer from one to three, the core moiety having at least one, five- to seven-membered ring and X being a racemic mixture, R or S enantiomer, slovate, hydrate, or salt of: ##STR1## ... | 09/01/1998 |
| 5723497 | Amine derivative and dermatologic preparation containing the same The present invention relates to an amine derivative represented by the following general formula (I) or (II): ##STR1## wherein R1 means a heteroatom-containing C1 -C40 hydrocarbon group which may have a ring structur... | 03/03/1998 |
| 5716995 | Anti-osteopathic composition An anti-osteopathic composition comprising as an active ingredient a compound represented by the following formula (I), (II) or (III): ##STR1## which is useful for therapeutic and prophylactic treatment of osteopathia such as osteoporosis and bone fr... | 02/10/1998 |
| 5622995 | Methods for control and mitigation of molluscs A method is provided for controlling the proliferation of molluscs in target habitat by applying to the habitat a compound or mixture of compounds which are amines, ethoxylated amines, quaternary amines, ethoxylated quaternary amines and cyclic amines.... | 04/22/1997 |
| 5216030 | Antimicrobial, low toxicity, blend composition of bis-quaternary ammonium compounds and polyvinylpyrrolidone An antimicrobial, low toxicity blend composition of several bis-quaternary ammonium compounds of defined structure, and in defined amounts of the composition, and polyvinylpyrrolidone, is described herein.... | 06/01/1993 |
| 5077033 | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide Balanced pH, thermo-irreversible gels are ideal vehicles for drug delivery to the eye of a mammal.... | 12/31/1991 |
| 5023008 | Anti-microbial composition containing aliphatic polygycidol adducts Novel nonionic antimicrobial amine glycidol compounds which may be used in cleaning compositions with anionics, nonionics or cationic surfactants as cleaning agents or a preservative in water-based functional fluids or surface coating compositions are rep... | 06/11/1991 |
| 4923887 | Liquid formulations of 1,2-benzisothiazolin-3-one, their preparation and their use Antimicrobially active liquid composition formulation which comprises 1,2-benzisothiazolin-3-one and at least one amine-oxyethylate of the formula ##STR1## wherein R is alkyl or alkenyl each having 2 to 22 carbon atoms and the sum of m and n is ... | 05/08/1990 |
| 4466976 | Antiinflammatory and antiallergic imidazole derivatives Imidazole derivatives of Formula I ##STR1## wherein AR1 and AR2 each independently represent phenyl optionally substituted by halogen atoms, alkyl groups, or alkoxy groups, R1 is pyrrolyl, indolyl, imidazolyl, or thiazolyl... | 08/21/1984 |
| 4166132 | Antiviral amine derivatives of glycerol and propanediols Novel amine and amidine derivatives of di-0-(n-higher alkyl and alkenyl)-glycerols and -propanediols, and their pharmaceutically acceptable acid addition salts, are useful for combating viral infections in mammals. Of particular interest is 1,3-di-0-... | 08/28/1979 |
