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| Number | Title | Issue Date |
| 7977387 | Aminobenzophenone compounds The invention provides novel compounds according to formula I relates to compounds with the general formula I said compounds being useful, e.g. in the treatment of inflammatory, ophthalmic diseases or cancer. ... | 07/12/2011 |
| 7754772 | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use The invention describes novel nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or re... | 07/13/2010 |
| 7696251 | Method for inhibiting neuronal cell death induced by oxidative glutamate toxicity A neuronal cell death induced by an oxidative glutamate toxicity is substantially inhibited by administrating to an mammal an effective amount of a phenylenediamine derivative compound of formula (I), wherein R is phenyl or butyl. | 04/13/2010 |
| 7253211 | (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for ... | 08/07/2007 |
| 7226949 | Compounds of use in the treatment of epilepsy, seizure, and electroconvulsive disorders The present invention provides pharmaceutical preparations and the uses thereof for preventing and/or treating seizures and other electroconvulsive disorders by administering a pharmaceutically effective amount of a therapeutic compound having the following formula ... | 06/05/2007 |
| 7227034 | Process for arylamine production Forming a 4-aminobiphenyl derivative arylamine compound, includes (i) providing a first disubstituted 4-aminobiphenyl compound; (ii) optionally formylating the first disubstituted 4-aminobiphenyl compound to form a bisformyl substituted compound where the first disu... | 06/05/2007 |
| 7122536 | (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for ... | 10/17/2006 |
| 7108864 | Tablet formation Disclosed is a non-sustained release pharmaceutical tablet composition which comprises a rapidly precipitating drug in an amount from about 5 to about 60% and at least one member selected from the group consisting of a binder in an amount of from about 2 to about 25... | 09/19/2006 |
| 7009080 | Process for producing halogenated aromatic amine compound A process for producing a halogenated aromatic amine compound by allowing an aromatic amine compound to react with a dihalogenated aromatic compound in the presence of i) a metallic catalyst having a phosphorus-containing ligand having at least one cyclic hydrocarbo... | 03/07/2006 |
| 6972287 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits The present invention provides a method of treating Alzheimer's disease using a compound of Formula (I). Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of the Formula (I) and a method of imaging amyloid deposits, as well... | 12/06/2005 |
| 6924313 | Substituted tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid trans: protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery d... | 08/02/2005 |
| 6835719 | Pesticidal composition An environmentally safe pesticidal liquid suspension composition including a mixture of sulfur combined with pyrethrins and/or pyrethroids is provided. The pesticidal composition is effective to control plant diseases, as well as insect and mite pests. The compositi... | 12/28/2004 |
| 6803388 | (R)-Chiral halogenated substituted n,n-bis-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for ... | 10/12/2004 |
| 6765023 | Use of substituted N, N-disubstituted reverse aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atheroscle... | 07/20/2004 |
| 6683099 | Substituted N,N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/27/2004 |
| 6677380 | Substituted N, N-disubstituted mercapto amino compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/13/2004 |
| 6677382 | Substituted N,N-bis-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating... | 01/13/2004 |
| 6608109 | Composition comprising L-arginine as a muscle growth stimulant and use thereof A composition for stimulating muscle growth, comprising an effective amount of L-arginine or a salt thereof, a pH control agent for controlling the pH at less than 7 and a pharmaceutically acceptable carrier. A method of using the composition to achieve m... | 08/19/2003 |
| 6592891 | Plaster for topical use containing heparin and diclofenac Plaster for topical use having an analgesic activity and at the same time being able to re-absorb haematomas, comprising: a substrate layer; an adhesive layer in the form of a hydrogel matrix containing a pharmaceutically acceptable diclofenac salt, heparin or... | 07/15/2003 |
| 6593347 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use The present invention describes novel nitrosated and/or nitrosylated nonsteroidal antiinflammatory compounds, and novel compositions comprising at least one nitrosated and/or nitrosylated nonsteroidal antiinflammatory compound, and, optionally, at least o... | 07/15/2003 |
| 6495567 | Triaryl methane compounds and their use in the treatment of diarrhea and scours A method and product for treating and preventing diarrhea and scours is provided. The method involves treating a subject who has diarrhea, or scours, or is at risk of getting diarrhea or scours with an aromatic compound of the invention. The products of t... | 12/17/2002 |
| 6476057 | Use of substituted N, N-disubstituted cycloalkyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for t... | 11/05/2002 |
| 6462092 | Use of substituted N, N-disubstituted reverse aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for t... | 10/08/2002 |
| 6458852 | Use of substituted N, N-bis-phenyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for t... | 10/01/2002 |
| 6458849 | use of substituted N,N-disubstituted mercapto amino compounds for inhibiting cholesteryl ester transfer protein activity The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkyamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for tr... | 10/01/2002 |
| 6403627 | Spin trapping pharmaceutical compositions and methods for use thereof Spin trapping compositions in general have now been discovered to be effective in treating a variety of disorders, including disorders such as those arising from ischemia, infection, inflammation, exposure to radiation or cytotoxic compounds, not just of ... | 06/11/2002 |
| 6331553 | Aromatic amine derivatives having NOS inhibiting action Compounds represented by the general formula (1): ##STR1## (where R1 and R2 are typically a hydrogen atom; R3 and R4 are typically a hydrogen atom or a lower alkyl group; R5 is typically a hydrogen at... | 12/18/2001 |
| 6297260 | Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use The present invention describes novel nitrosated and/or nitrosylated nonsteroidal antiinflammatory compounds, and novel compositions comprising at least one nitrosated and/or nitrosylated nonsteroidal antiinflammatory compound, and, optionally, at least o... | 10/02/2001 |
| 6277829 | Process for preparing of aqueous formulation for opthalmic use The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical use in the ocular bacterial infections, more preferably i... | 08/21/2001 |
| 6274570 | Pesticidal compositions A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a) a castor oil ethoxylate having 30-50 mol ethoxylate, (b) a... | 08/14/2001 |
| 6267946 | Inhibitory effects of synthetic and natural colorants on carcinogenesis VI A method of reducing the percentage of Epstein-Barr virus genome-carrying cells which exhibit Epstein-Barr virus early antigen induction, wherein the Epstein-Barr virus genome-carrying cells have been cultivated in the presence of a tumor-promoting chemic... | 07/31/2001 |
| 6251943 | Method of treating or preventing septic shock by administering a MEK inhibitor The present invention provides a method for treating or preventing septic shock. Specifically, the present invention provides a method of treating or preventing septic shock by administering to a patient a MEK inhibitor.... | 06/26/2001 |
| 6235736 | 3-anilino-2-cycloalkenone derivatives A 3-anilino-2-cycloalkenone derivative of the formula (I): ##STR1## wherein, R1 represents a C1 to C8 alkyl group, which may have a substituent, except for a methyl group, a C3 to C7 cycloalkyl group,... | 05/22/2001 |
| 5985880 | Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds A method of reducing, treating or preventing drug-mediated respiratory depression in an animal, incident to the administration to said animal of a respiratory depression-mediating drug, comprising administering to the animal receiving said drug an effecti... | 11/16/1999 |
| 5780510 | 2,4-disulfo phenyl butyl nitrone, its salts and their use as pharmaceuticals 2,4-disulfonyl -phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central ... | 07/14/1998 |
| 5739169 | Aromatic compounds for inhibiting immune response Novel compounds ##STR1## wherein R1 to R13 are independently selected from C2 -C4 linear and branched alkyls, H, NH2, CH3, OR14, fluorine, chlorine, iodine, NO2, ... | 04/14/1998 |
| 5679660 | Pharmaceutical composition comprising diclofenac and cyclodextrin A method of preparing an injectable pharmaceutical or veterinary composition which comprises either diclofenac or a salt thereof and 2-hydroxypropyl beta-cyclodextrin, or an inclusion complex of diclofenac or a salt thereof and 2-hydroxypropyl beta-cyclod... | 10/21/1997 |
| 5633283 | Method for treating multiple sclerosis Provided is a method of treating multiple sclerosis employing certain phenol and benzamide compounds.... | 05/27/1997 |
| 5614560 | Method of preventing NMDA receptor-mediated neuronal damage Disclosed is a method for reducing non-ischemic NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a compound of the formula shown in FIG. 1 (or a physiologically-acceptable salt thereof), wherein R1 includes an a... | 03/25/1997 |
| 5475032 | 2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceuticals 2,4-disulfonyl -phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central ... | 12/12/1995 |
