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| Number | Title | Issue Date |
| 4914133 | Amino compounds and fungicides containing them Amino compounds of the formula ##STR1## where R1 is alkyl, A is alkylene or alkenylene, and Ar is aryl, and their acid addition salts, and fungicides containing these compounds.... | 04/03/1990 |
| 4913891 | Positron emitter labeled enzyme inhibitors This invention involves a new strategy for imaging and mapping enzyme activity in the living human and animal body using positron emitter-labeled suicide enzyme inactivators or inhibitors which become covalently bound to the enzyme as a result of enzymati... | 04/03/1990 |
| 4910208 | Method of inhibiting leukotriene biosynthesis by oral administration of p-aminophenols or derivatives thereof A method is provided for inhibiting leukotriene biosynthesis and thus treating asthma, psoriasis or inflammation by oral administration of p-aminophenols having the structure ##STR1## wherein m is 0 to 5; X is CH or N; R1 and R2... | 03/20/1990 |
| 4898889 | Methods for the treatment of hypertension Acetylene compounds of the formula (I): ##STR1## wherein Y, R1, R2, R3, and R4 are as described herein, m is 0-3, n is 0-2 and Ar is phenyl or an aromatic heterocycle are disclosed. The compounds possess an... | 02/06/1990 |
| 4897425 | Fungicidal cyclohexylamines Cyclohexylamines of the formula ##STR1## where X is a single bond or an alkylene chain, Y is hydrogen or an aryl, cyclohexyl, 4-cyclohexylcyclohexyl, perhydro-1- or 2-naphthyl or piperidyl radical, R1 and R2 are hydrogen, alkyl,... | 01/30/1990 |
| 4883804 | Aromatic compounds There are described compounds of formula I, ##STR1## in which X represents a C2 to 8 alkylene chain optionally interrupted by a double bond or by S(O)n, wherein n is 0, 1 or 2; Y represents O or NH, l and m each independently represent 2, 3 or ... | 11/28/1989 |
| 4882358 | Carbocyclic derivatives The present invention relates to compounds of formula (I) ArCH2 R1 (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon at... | 11/21/1989 |
| 4880841 | Process of producing phenethylamine derivatives Phenethylamine derivatives shown by the general formula ##STR1## wherein Ro represents a lower alkyl group; R1 represents a lower alkyl group or a lower alkoxy group; R2 represents hydrogen atom or a hydroxyl group; R3 | 11/14/1989 |
| 4880833 | Synergistic pharmaceutical compositions, their production and use The invention relates to a synergistic pharmaceutical composition, which comprises as an active ingredient a combination of 1-phenylalanine and (-)-deprenyl [(-)-N-(1-phenylisopropyl)-N-methyl-N-propinylamine hydrochloride] and optionally carbidopa [... | 11/14/1989 |
| 4876284 | 1-alkyl-2-aminotetralin derivatives Compounds of the formula ##STR1## wherein R3 and the NR1 R2 group are in a cis-position to each other and wherein Y is OH, R4 COO, (R5)2 NCOO or R6 O either in position 5 or... | 10/24/1989 |
| 4873262 | 8-Substituted 2-aminotetralins New 8-substituted 2-aminotetralins can be prepared from the corresponding aminotetralins or tetralones. They can be used in medicaments.... | 10/10/1989 |
| 4820737 | Lacrimal secretion stimulant (lss) Ophthalmic compositions useful as tear stimulants when topically applied to the eye for effective treatment of dry eye syndrome.... | 04/11/1989 |
| 4808625 | Phenanthrene derivatives The present invention relates to compounds of formula (I) or a monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30 carbon atoms in total); ethers, esters thereof; acid addition salts thereof; wherein Ar is a ... | 02/28/1989 |
| 4804406 | ଲ-naphthylalkylamines Fungicidally active novel ଲ-naphthylalkylamines of the formula ##STR1## in which Ar represents optionally substituted ଲ-naphthyl and R1 and R2, which can be identical or different, represent alkyl or alkenyl or R1 | 02/14/1989 |
| 4803225 | Dihydroxy-phenethylamino compounds useful as pharmaceuticals There are provided compounds of formula I, ##STR1## and pharmaceutically acceptable derivatives thereof. There are also described the use of the compounds of formula I as pharmaceuticals, methods for making the compounds and pharmaceutical, e.g. card... | 02/07/1989 |
| 4803200 | Substituted dialkanolamines, sulfur analogs and condensed 1,4-oxazine derivatives thereof in viral disease treatment Substituted dialkanolamines, oxazine and sulfur analogs thereof, useful in treating shipping fever syndrome in mammals are disclosed having the formula: ##STR1## wherein: Ar is ##STR2## Z is oxygen or sulfur; R is selected from hydrogen, lo... | 02/07/1989 |
| 4797410 | Suppression of withdrawal symptoms in opioid-induced tolerance or dependence A method for suppressing withdrawal symptoms in an opioid-induced tolerant or physically dependent individual is disclosed. The method comprises administering to such individual an effective amount of a calcium channel blocking drug or pharmaceutically ac... | 01/10/1989 |
| 4791123 | Insecticidal triffluormethyl alkane derivatives There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R1, R2, R3, R4 and A have the meanings given in the description, processes for their preparation and ins... | 12/13/1988 |
| 4786653 | Treatment of neurotransmitter-linked drug abuse Treatment of the abuse of those addictive drugs whose apparent mode of operation includes first an enhancement of neurotransmitter activity and subsequently a reduction in that activity--and in accompanying pleasurable sensations--to such an extent that a... | 11/22/1988 |
| 4742084 | Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives Acetylenes of the formula (I): ##STR1## wherein Y, m, R1, R2, q, Alk, R3 n and R4 are as defined herein and Ar1 and Ar2 are aromatic, including the salts and ammonium derivatives of fo... | 05/03/1988 |
| 4721786 | ଲ-naphthylalkylamines Fungicidally active novel ଲ-naphthylalkylamines of the formula ##STR1## in which Ar represents optionally substituted ଲ-naphthyl and R1 and R2, which can be identical or different, represent alkyl or alkenyl or R1 | 01/26/1988 |
| 4717729 | Triphenylene derivatives The present invention relates to compounds of formula (I) ##STR1## wherein Ar is a triphenylene or substituted triphenylene ring system; R1 is a C1-3 alkylene moiety; R2 is hydrogen or a C1-6 alkyl group; R3 | 01/05/1988 |
| 4695589 | Alpha-(aminoalkyl-4-hydroxy-3-(alkylthio)benzenemethanols Alpha-(aminoalkyl)-4-hydroxy-3-(alkylthio)benzenemethanols useful as intermediates and as antihypertensive agents are prepared by reduction of the corresponding aminoalkyl 4-hydroxy-3-(alkylthio)phenyl ketones.... | 09/22/1987 |
| 4690935 | Inhibition of tumor growth and metastasis with calcium channel blocker compounds The use of calcium channel blocker compounds as antitumor and antimetastatic agents in mammals in vivo and in standard laboratory experimets with tumor cells in vitro is described. In particular the use of nimodipine (Bay e 9736) or nifedipine (Bay a 1040... | 09/01/1987 |
| 4680310 | Tetrahydronaphthalene derivatives Tetrahydronaphthalene derivatives of the formula ##STR1## wherein Y, m, n, R and R1 to R9 are as set forth herein, are described. These compounds have a pronounced calcium-antagonistic and anti-arrhythmic activity and can accord... | 07/14/1987 |
| 4657929 | Compounds There are provided pharmaceutical compounds useful in treating hypertension, heart diseases and renal failure. These compounds are 4-hydroxy phenethylamines wherein the 3 position on the phenyl nucleus is occupied by either an amino, amide, carbamyl, urea... | 04/14/1987 |
| 4649161 | Method for treating depression with d-fenfluramine D-fenfluramine is administered to a human patient having seasonal depression or other forms of bipolar depression in order to alleviate or cure the depression.... | 03/10/1987 |
| 4629727 | Therapeutic agents Compounds of formula I ##STR1## in which n=0 or 1; in which, when n=0, R1 is H, an alkyl, a cycloalkyl, a cycloalkylmethyl, an alkenyl or, an alkynyl group a heterocyclic ring or an optionally substituted phenyl ring or when n=1, R | 12/16/1986 |
| 4628064 | Epinine and the therapeutic use thereof Pharmaceutical compositions which contain epinine or a pharmaceutically acceptable salt thereof, and allow to reach a release of epinine comprised between 0.5 and 5 μg/Kg/minute. Said compositions are useful in treating congestive heart failures; they st... | 12/09/1986 |
| 4608391 | Catecholamine derivatives, a process for their preparation and pharmaceutical compositions thereof New dopamine derivatives are disclosed, which are tertiary amines and which exhibit especially dopaminergic properties, and which have the formula ##STR1## wherein R1 signifies an alkyl group containing at least 4 carbon atoms, a cycloalky... | 08/26/1986 |
| 4605673 | 7H-dibenzo(a,c,)cyclohepten-5-one-(7) derivatives The invention is concerned with 7H-dibenzo(a,c)-cyclohepten-5-one-(7) derivatives of general formula I ##STR1## wherein R1 and R2 can be the same or different, a hydrogen atom, an alkyl radical containing 1 to 3 carbon atoms, or... | 08/12/1986 |
| 4603131 | Method and composition for treating and preventing irritation of the mucous membranes of the nose A method and composition for preventing and treating irritation of the mucous membranes of the nose wherein a tricyclic anti-depressant topically applied to the nose is effective prophylactically to prevent irritation and a combination of the tricyclic an... | 07/29/1986 |
| 4585796 | Novel phenethanolamines The tertiary amines of the formula ##STR1## wherein n represents a whole number of 1 to 5; X1 represents phenyl or phenyl mono-, di- or tri-substituted by R1, R2 and R3 ; X2 represents hydrogen, lower... | 04/29/1986 |
| 4564637 | Method for maintaining corneal shape after radial keratotomy The relatively flattened shape of a cornea following radial keratotomy is maintained by administering to the eye a chemical compound which effectively increases intraocular pressure therein.... | 01/14/1986 |
| 4529604 | N,N-Di-(n-Propyl)dopamine derivatives N,N-Di-(n-propyl)dopamine derivatives having peripheral dopamine receptor agonist activity prepared by synthetic routes known for phenethylamines. The renal vasodilator effect of 3,4-dihydroxy-N,N-di(n-propyl)-phenethylamine is potentiated by the con... | 07/16/1985 |
| 4511582 | Phenanthrene derivatives The present invention relates to compounds of formula (I) ##STR1## wherein Ar is a phenanthrene or substituted phenanthrene ring system; R1 is a C1-3 alkylene moiety; R2 is hydrogen or a C1-6 alkyl group; R3 | 04/16/1985 |
| 4485114 | Arylglyoxals useful as hypoglycemic agents Arylglyoxals which are new compounds, which are active as hypoglycemic agents.... | 11/27/1984 |
| 4479932 | Brain-specific drug delivery Centrally acting drug species are site-specifically/sustainedly delivered to the brain by administering to a patient in need of such treatment a therapeutically effective amount of the target drug species [D] tethered to a reduced, blood-brain barrier pen... | 10/30/1984 |
| 4477470 | Method for producing diuresis using m-amino--methylphenethylamine m-Amino--methylphenethylamine, when administered internally, induces water diuresis in patients having edema.... | 10/16/1984 |
| 4474751 | Ophthalmic drug delivery system utilizing thermosetting gels This invention describes the application of selected polymers as novel drug delivery systems which use the body temperature and pH to induce a liquid to gel transition of the polymer which contains a drug or therapeutic agent therein. The goal of such a d... | 10/02/1984 |
