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| Number | Title | Issue Date |
| 4134996 | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.... | 01/16/1979 |
| 4124722 | Therapeutic method of controlling tachycardia Alpha-[(lower alkylamino)alkyl]-4-hydroxy-3-(alkylthio, alkylsulfinyl or alkylsulfonyl)benzenemethanols which have ଲ-adrenergic blocking activity and which are therefore useful in controlling tachycardia are prepared by reduction of the correspondin... | 11/07/1978 |
| 4123555 | Sulfide compounds and methods and compositions for treating depression Compounds, pharmaceutical preparations containing same, and method of treating depression in mammals, the compounds being of the formula I ##STR1## or an acid addition salt thereof, particularly a pharmacologically or pharmaceutically acceptable salt... | 10/31/1978 |
| 4110471 | N-vinyloxyethyl--methyl-ଲ-phenethylamines as alcohol intake suppressing agents N-vinyloxyethyl--methyl-ଲ-phenethylamines represented by the formula ##STR1## wherein R is H, halo or CF3 and acid addition salts thereof have been found to be useful as alcohol intake suppressing agents.... | 08/29/1978 |
| 4104402 | 5,6-Dihydroxy aminotetralol compounds Novel aminotetralol compounds of the formula ##STR1## wherein Z1 and Z2 are hydrogen or an alkyl group and R1 is a substituted acyclic hydrocarbon group or a cyclic hydrocarbon group, and their pharmaceutically accep... | 08/01/1978 |
| 4104383 | Derivatives of phenylpropenylamine Compounds having psychostimulant, antispasmodic, hypotensive and analgesic properties are disclosed. The compounds have the formula: ##STR1## in which R2 is selected from the group consisting of a hydrogen atom and a halogen atom; R1 | 08/01/1978 |
| 4093648 | Therapeutically active benzoic acid derivatives and a process for preparing them Therapeutically active 2- and 3-substituted benzoic acid derivatives having the general formula ##STR1## wherein X is OH, NH2 or an anilino group having the phenyl ring unsubstituted or substituted by chlorine or by a 4-ethoxy group; or ... | 06/06/1978 |
| 4087551 | Amino-bicycloheptanes Pharmaceutical compositions are described in which the active ingredient is a 7,7-dimethyl-[2,2,1]-bicycloheptane having at the 1-position a substituted or unsubstituted amino or aminomethyl group. The active ingredients have been found to possess antivir... | 05/02/1978 |
| 4083997 | 10-(2-Substituted-amino-ethyl)-10,11-dihydro-5-meth ylene-5H-dibenzo[a,d]cycloheptenes 10-(2-substituted-aminoethyl)-10,11-dihydro-5-methylene-2 or 3 7 or 8-substituted or unsubstituted-5H-dibenzo[a,d]cycloheptenes e.g., 10-(2-dimethylaminoethyl)-10,11-dihydro-5-methylene-5H-dibenzo[a,d]cyclohe ptene, prepared by various methods including ac... | 04/11/1978 |
| 4066747 | Polymeric orthoesters housing beneficial drug for controlled release therefrom This invention concerns polymeric orthoesters having a repeating mer comprising a hydrocarbon radical and an orthoester functionality of the general formula: ##STR1## wherein R1 is a monovalent radical, R2 is a hydrocarbon radic... | 01/03/1978 |
| 4061775 | Polyamine compounds as antibacterial agents Novel diphenyl and loweralkyl substituted diphenyl polyamines are useful antimicrobial agents, as well as algae inhibitors. They are especially useful because of their low toxicity, and as such are advantageously included as the active agent in surgical s... | 12/06/1977 |
| 4058624 | Broad spectrum antibacterial compositions containing tris (hydroxymethyl)-aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines A composition comprising tris-(hydroxymethyl)aminomethane and diphenyl and loweralkyl substituted diphenyl polyamines, their acid addition salts, and mixtures thereof are useful as antibacterial agents. The composition is particularly useful because of th... | 11/15/1977 |
| 4058642 | 2-Amino-3-(3'-hydroxy-phenyl)-propanols and salts thereof Compounds of the formula ##STR1## wherein R1 is hydrogen, chlorine, hydroxyl, trifluoromethyl, methyl or methoxy, and R2 is hydrogen, alkyl of 1 to 2 carbon atoms or benzyl; And non-toxic, pharmacologically acceptable acid addition s... | 11/15/1977 |
| 4056632 | 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use Compounds, pharmaceutical preparations containing same, and method of treating depression in mammals, the compounds being of the formula I ##STR1## or an acid addition salt thereof, particularly a pharmacologically or pharmaceutically acceptable salt... | 11/01/1977 |
| 4055665 | Treating arrythmia with phenylthioaralkylamines Phenylthioaralkylamines and 2-phenylthiobenzylamines are prepared by reaction of the corresponding phenylthiobenzoyl chloride or homologs thereof with ammonia or an amine to produce the corresponding phenylthiobenzamide or N-substituted or N,N-disubstitut... | 10/25/1977 |
| 4055664 | Pharmaceutical preparations containing 4-(4-biphenylyl) butylamines and treatment of the animal organism therewith Preparations containing 4-biphenylyl butylamines or pharmaceutically acceptable salts thereof and methods of using the same whereby a host, including man, to whom such preparations are administered, is provided with anti-inflammatory, antipyretic and anal... | 10/25/1977 |
| 4049791 | Prolonged acting appetite suppressant and anti-obesity compositions containing amphetamine adipate, dextroamphetamine adipate, amphetamine sulfate and dextroamphetamine sulfate as the active agents A prolonged acting appetite suppressant and anti-obesity composition in oral administration form which comprises an effective amount of a synergistic combination of amphetamine adipate, dextroamphetamine adipate, amphetamine sulfate and dextroamphetamine ... | 09/20/1977 |
| 4035512 | Aminotetralols Novel aminotetralol compounds of the formula ##STR1## wherein R1 is hydrogen, acyl derived from carboxylic acid, or a hydrocarbon group which may be substituted; --OZ1 is hydroxyl which may be protected; Y is hydrogen, acyl, hyd... | 07/12/1977 |
| 4034103 | Aralkylamino sulfones having spasmolytic activities An aralkylamino sulfone such as 4- [n-ethyl -[1-methyl-2-(4-methoxy-phenyl)] ethylamino] -butyl sulfone is useful as a spasmolytic for the smooth muscle system.... | 07/05/1977 |
| 4034113 | Treatment of senile geriatric patients to restore performance Compounds of the formula ##STR1## wherein R1, R2 and R3 are alike or different and each is (lower)alkyl, including the racemic mixtures and the dextrorotatory and levorotatory isomers, and the pharmaceutically accepta... | 07/05/1977 |
| 4027035 | Therapeutic uses of adamantanealkylamine compounds 2-Phenyl adamantane alkyl amines are useful as antidepressants and anti-Parkinsonism agents, and may be prepared by a Friedel Crafts synthesis involving reaction of benzene with corresponding 2-halogeno compounds.... | 05/31/1977 |
| 3998971 | Novel N-vinyloxyethyl--methyl-ଲ-phenethylamines for depressing appetite Novel N-vinyloxyethyl--methyl-ଲ -phenethylamines represented by the formula ##STR1## wherein R is H, halo or CF3 and acid addition salts thereof. The compounds are useful as appetite depressants.... | 12/21/1976 |
| 3996381 | Amphetamine derivatives Compounds having the general formula ##STR1## or pharmaceutically acceptable salts thereof, in which formula R1 and R2 are the same or different and each represents a hydrogen atom, a lower alkyl group or a halogen atom, R3... | 12/07/1976 |
| 3987201 | Method for treating arrhythmia Cardiac arrhythmia is treated orally or parenterally with diarylalkylamines and diarylalkenylamines.... | 10/19/1976 |
| 3987200 | Method for increasing cardiac contractility N-Mono or dihydroxyphenylalkyl dopamine derivatives and salts thereof are inotropic agents useful in a method for treatment of acutely depressed cardiac insufficiency.... | 10/19/1976 |
| 3980770 | Polymerization products containing amino groups useful in serum cholesterol level control A pharmaceutical product containing amino groups, which product: A. is comprised of residues of one or more diamines of the general formula which residues are interconnected by bridges between the residues to form a three-dimensional network, the bridges being boun... | 09/14/1976 |
| 3968245 | Sympathomimetic topical and percutaneous administration with halogenated promoters Dermal compositions are disclosed with comprise trichloroethanol or trifluoroethanol as one component of a vehicle having solubilized therein a drug or other beneficial chemical compound. Also disclosed is a method for administering a drug or other benefi... | 07/06/1976 |
| 3933998 | 4-[2-(Isopropylamino)ethyl]pyrocatechol intraocular pressure lowering process Topical administration of 4-[2-(isopropylamino)ethyl]pyrocatechol to the mammalian eye reduces intraocular pressure without side effects generally associated with adrenergic activation such as tachycardia, mydriasis, hypertension and hypotension.... | 01/20/1976 |
| 3933911 | 1-Aryl-2-amidoalkylaminoethanol derivatives Novel 1-hydroxyaryl-2-amidoalkylaminoethanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart failure and other diseases. The compounds possess ଲ-adrenergic... | 01/20/1976 |
