Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 8188150 | Use of beta-aminoalcohols in the treatment of inflammatory disorders and pain A compound for therapeutic use, of the formula (I), wherein R1 is aryl or heteroaryl optionally substituted with R5; R2 is H, alkyl or CH2OH or forms part of a ring with R4; R3 is H, alkyl or CH2... | 05/29/2012 |
| 8048928 | Therapeutic agent for treating liver disease containing 2-amino-1,3-propanediol derivative as active ingredient, and method for treating liver disease A method for treating a liver disease such as hepatitis, comprising administering to a patient having the liver disease, an effective amount of a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure, and represented by the following formu... | 11/01/2011 |
| 8030357 | Use of bupropion metabolites for the treatment of inflammatory disorders Compounds that may be used for the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro-inflammatory cytokines are of formula (I) or a salt thereof. ... | 10/04/2011 |
| 8017657 | Composition for the treatment and prevention of endothelial dysfunction A composition and method for pain relief and the treatment and prevention of endothelial dysfunction the cause of atherosclerosis, cardiovascular disease, hypertension, and stroke in mammals comprising a therapeutically effective amount of anti-inflammatory agents c... | 09/13/2011 |
| 7964649 | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity Hydrindane analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at S1P receptors. ... | 06/21/2011 |
| 7947742 | Inhalable epinephrine The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described ... | 05/24/2011 |
| 7928146 | Pharmaceutical composition for treating fecal incontinence and anal itch Fecal incontinence and anal itch can be treated by administration, more particularly by local application to the anus, of an αadrenergic blocker, nitric oxide synthase inhibitor, prostaglandin F2α, dopamine, morphine, β-blockers, and 5-Hydroxytryptamin... | 04/19/2011 |
| 7846973 | Chemical process and new crystalline form The present invention relates to the preparation of a β2 adrenergic agonist in crystalline salt form. In particular the invention relates to preparation of a crystalline salt of compound (I) in particular a crys... | 12/07/2010 |
| 7786173 | Tetralin analogs having sphingosine 1-phosphate agonist activity Tetralin analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at S1P receptors. ... | 08/31/2010 |
| 7541385 | Bronchodilating β-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 06/02/2009 |
| 7524887 | 2-amino-1,3-propanediol compounds for the treatment of acute pain The present invention relates to a method for the prophylaxis or treatment of pain using compounds of formula I, in which R, R2, R3, R4 and R5 have the meanings indicated in the specification. ... | 04/28/2009 |
| 7473710 | Bronchodilating beta-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 01/06/2009 |
| 7465756 | Bronchodilating beta-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 12/16/2008 |
| 7462645 | Bronchodilating beta-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 12/09/2008 |
| 7442839 | Phenethanolamine derivative for the treatment of respiratory diseases The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis an... | 10/28/2008 |
| 7432247 | Methods of cardioprotection using dichloroacetate in combination with an inotrope The present invention provides compositions and methods for maintaining cardiac function by administering dichloroacetate (DCA) in combination with an inotrope. ... | 10/07/2008 |
| 7431916 | Administration of medicinal dry powders A method of administering a metered dry powder combined dose of finely divided dry medication powders is disclosed, wherein said method comprises providing a relative motion between a nozzle of a dry powder inhaler and a dose bed carrying said combined dose of finel... | 10/07/2008 |
| 7429390 | Stable pharmaceutical compositions, processes for making the same and methods of their use The present invention is generally related to alcohol free, liquid ranitidine formulations for oral administration. In particular, the present invention is related to stable, syrup formulations having ranitidine as an active ingredient for oral administration, proce... | 09/30/2008 |
| 7427639 | β2-adrenergic receptor agonists Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.... | 09/23/2008 |
| 7402673 | Diamine βadrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2 adrenergic receptor... | 07/22/2008 |
| 7361787 | Phenethanolamine derivatives for treatment of respiratory diseases The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases ... | 04/22/2008 |
| 7354913 | High storage stability inhalable compositions Inhalable pharmaceutical compositions are provided, for use in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD). These compositions have high storage stability, and include formoterol and a corticostero... | 04/08/2008 |
| 7288263 | Compositions and methods for treatment of skin discoloration A cosmetically acceptable product for application to human skin is disclosed. The novel compositions are particularly suited for skin lightening and for diminishing the appearance of “dark circles” under the eyes. The compositions include any of several vasocons... | 10/30/2007 |
| 7288534 | Sphingomyelin enhancement of tumor therapy Cytotoxic tumor therapy in a patient is enhanced by co-administration of sphingomyelin. The invention most likely enhances a tumor cell's ability to undergo ceramide-induced apoptosis by increasing the levels of sphingomyelin in all cellular compartments, thereby pr... | 10/30/2007 |
| 7273623 | Process for preparing tannate tablet, capsule or other solid dosage forms An active pharmaceutical ingredient is combined with tannic acid to form a tannate salt complex of the active ingredient. The active ingredient tannate salt complex without isolation or purification is then blended with pharmaceutically acceptable excipients to form... | 09/25/2007 |
| 7268149 | Cyclothiocarbamate derivatives as progesterone receptor modulators and methods of treating skin disorders The present invention provides methods of treating skin disorders includes delivering to a mammal a composition containing a compound of formula I, or tautomers thereof, in a regimen, wherein formula I is: and wh... | 09/11/2007 |
| 7253211 | (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for ... | 08/07/2007 |
| 7217738 | β2-adrenergic receptor agonists Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also useful in the treatment of nervous system injury and premature labor.... | 05/15/2007 |
| 7214826 | Amine compounds and inhibiting neurotransmitter reuptake The invention relates to amine compounds as well as methods and materials involved in modulating neurotransmitter reuptake. Specifically, the invention provides amine compounds, methods for synthesizing amine compounds, and methods for inhibiting neurotransmitter re... | 05/08/2007 |
| RE39593 | 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects 1-phenyl-3-dimethylaminopropane compounds corresponding to the formula I a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical compositions. ... | 04/24/2007 |
| 7153845 | Bioadhesive progressive hydration tablets A bioadhesive controlled, extended release progressive hydration composition wherein the active ingredient may be protected from water or the surrounding environment, thereby protecting it from metabolism or from other degradation caused by moisture, enzymes, or pH ... | 12/26/2006 |
| 7144908 | Agonists of beta-adrenoceptors The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases. | 12/05/2006 |
| 7135497 | Treating neural conditions resulting from spinal cord contusions and other causes β2-agonists, such as clenbuterol and salbutamol can enhance the recovery of locomotive function and/or neuromuscular strength following spinal cord injuries or as a result of degenerative neural conditions such as Mnd. Pharmacological compositions for tr... | 11/14/2006 |
| 7135500 | Dihydroxymethylphenyl derivatives, processes for preparing them, and their use as pharmaceuticals A compound of formula 1 wherein the groups R1, R2, R3, and R4 may have the meanings given in the claims and in the specification, processes for preparing them, and thei... | 11/14/2006 |
| 7125892 | Aryl aniline βadrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds of formula (I): wherein R1–R13 and w have any of the values described in the specification. The invention al... | 10/24/2006 |
| 7107985 | Pharmaceutical combination The present invention relates to a combination comprising (a) an adenosine A2a receptor agonist as define herein and (b) an adrenergic β2 receptor agonist, for simultaneous, sequential or separate administration by the inhaled route in the treatment of a... | 09/19/2006 |
| 7101572 | Taste masked aqueous liquid pharmaceutical composition A substantially taste masked liquid pharmaceutical composition containing a pharmaceutically effective amount of an unpleasant tasting drug dissolved or dispersed in an aqueous excipient base, said excipient base comprising polyvinyl pyrrolidone and/or copolyvidone,... | 09/05/2006 |
| 7098364 | Phenylethanolamine compounds as β-receptor agonists, and methods of use and preparation thereof The invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 is H, chlorine, or bromine; R2 is electron attractive groups selected from the group consisting of CF3, CN, fluorine, CH3 | 08/29/2006 |
| 7094429 | Process for preparing tannate liquid and semi-solid dosage forms An active ingredient from the group of an antihistamine, a decongestant, an antitussive or anticholinergic is dissolved in a suitable solvent and added to a dispersion of tannic acid in water to form the tannate salt complex of the active ingredient. The active ingr... | 08/22/2006 |
| 7067502 | Combinations of formoterol and mometasone furoate for asthma A medicament containing, separately or together, (A) formoterol or a pharmaceutically acceptable salt thereof or a solvate of formoterol or a solvate of the salt and (B) mometasone furoate, for simultaneous, sequential or separate administration in the treatment of ... | 06/27/2006 |
