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| Number | Title | Issue Date |
| 8114912 | Bronchodilating β-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 02/14/2012 |
| 8071653 | Use of RR/SR-ractopamine A method of promoting weight loss in animals or humans by administering thereto a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed. ... | 12/06/2011 |
| 8048927 | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen The present invention provides methods for treating and preventing benign breast disease by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogen... | 11/01/2011 |
| 7985775 | Methods of accelerating muscle growth, decreasing fat deposits and improving feed efficiency in livestock animals A method of promoting or improving the feed efficiency and the muscle to fat ratio in animals by administering to the animals a therapeutically effective amount of a pure or substantially pure RR-isomer of ractopamine is disclosed. Also disclosed are animal feed pre... | 07/26/2011 |
| 7834063 | Benzonitryl and nitrobenzyl derivatives that modulate androgen receptors This invention relates to benzonitryl and nitrobenzyl derivatives that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds. These compounds are useful, for exampl... | 11/16/2010 |
| 7786172 | Treatment of mastalgia with 4-hydroxy tamoxifen A method of treatment comprises administering 4-hydroxy tamoxifen percutaneously to a patient having mastalgia. The 4-hydroxy tamoxifen may be formulated in a hydroalcoholic gel or an alcoholic solution. ... | 08/31/2010 |
| 7767717 | Treatment and prevention of excessive scarring with 4-hydroxy tamoxifen The present invention provides a method for treating or preventing excessive scarring, including keloid and hypertrophic scars, by administering 4-hydroxy tamoxifen to a patient with excessive scarring or a wound at risk for developing excessive scarring. ... | 08/03/2010 |
| 7737185 | Methods and compositions with -clomiphene The present invention relates to the use of compositions comprising trans-clomiphene for treating wasting, especially a loss of muscle mass. The invention is also directed to methods for treating wasting in a patient with chronic obstructive pulmonary disorder. The ... | 06/15/2010 |
| 7723392 | Use of RR/SR-ractopamine A method of promoting or improving the feed efficiency and the muscle-to-fat ratio in animals by administering to the animals a therapeutically effective amount of a mixture of RR-ractopamine and SR-ractopamine is disclosed. Manufacturing methods for making RR/SR-ra... | 05/25/2010 |
| 7718705 | Methods of using rapid-onset selective serotonin reuptake inhibitors for treating sexual dysfunction Methods for the prevention, treatment, or management of sexual dysfunction, such as premature ejaculation, by administering to a patient in need of therapy a therapeutically effective amount of a rapid-onset selective serotonin reuptake inhibitor on an as-needed bas... | 05/18/2010 |
| 7514475 | Benzylamine analogues A compound of the formula (I): wherein R1 is a C1-C6 alkyl, an amino, a (C1-C6 alkyl)amino, a di(C1-C6 alkyl)amino or a nitrogen-containing satura... | 04/07/2009 |
| 7507769 | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen The present invention provides methods for treating and preventing benign breast disease by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogen... | 03/24/2009 |
| 7504437 | Benzylamine analogues A compound of the formula (I): wherein R1 represents C1–C6 alkyl, amino(C1–C6 alkyl)amino, di(C1–C6 alkyl)amino or a nitrogen-containing sat... | 03/17/2009 |
| 7439398 | Enantiomerically pure atomoxetine and tomoxetine mandelate The present invention provides enantiomerically pure (R)-(−)-tomoxetine (S)-(+)-mandelate and atomoxetine HCl. The present invention further provides enantiomerically pure (R)-(−)-tomoxetine (S)-(+)-mandelate prepared from racemic tomoxetine. The present inventi... | 10/21/2008 |
| 7439241 | Compounds, formulations, and methods for treating or preventing rosacea In methods, compounds, and topical formulations for treatment of rosacea incorporating compounds represented by the formulas below: wherein each of R1, R2, and R3 is independently hydrogen, ... | 10/21/2008 |
| 7427414 | Modified release oral dosage form using co-polymer of polyvinyl acetate Once a day modified release oral dosage form comprising of granules or pellets which are either compressed into tablet or filled inside the capsule, wherein the pellet has a core of active ingredient coated on non pareil seeds with a rate controlling functional coat... | 09/23/2008 |
| 7423181 | Aminoalkoxy-functional chalcones The invention provides novel alkoxyaminochalcone derivatives and analogues thereof. Use of the compounds, or compositions comprising them, as pharmaceutically active agents, in particular against bacterial and parasitic infections, is also disclosed. The invention f... | 09/09/2008 |
| 7393864 | Use of ClC3 chloride channel blockers to modulate vascular tone The present invention provides methods for the modulation of vascular tone in a patient having compromised vascular tissue, which methods comprise the administration of a chloride channel blocking agent or a pharmaceutically acceptable salt thereof. ... | 07/01/2008 |
| 7384983 | Inhibitor of monoamine uptake The present invention provides compounds and methods for the inhibition of monoamine uptake in mammals. ... | 06/10/2008 |
| 7368480 | Methods and compositions with trans-clomiphene The present invention relates to the use of compositions comprising trans-clomiphene for treating men with hypogonadism. The invention is also directed to methods for treating males with hypogonadism. The present invention is also directed to methods of decreasing c... | 05/06/2008 |
| 7365085 | Compounds and methods Disclosed is a compound having the formula: pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined... | 04/29/2008 |
| 7361787 | Phenethanolamine derivatives for treatment of respiratory diseases The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases ... | 04/22/2008 |
| 7355079 | Thyronamine derivatives and analogs and methods of use thereof Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ... | 04/08/2008 |
| 7348362 | Bronchodilating β-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 03/25/2008 |
| 7339079 | Thyronamine derivatives and analogs and methods of use thereof Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ... | 03/04/2008 |
| 7338953 | Method of treating chronic fatigue syndrome Disclosed herein are methods of treating an individual suffering from, chronic fatigue syndrome. The methods generally include administration of a therapeutic amount of racemic reboxetine, or a pharmaceutically acceptable salt thereof, to the individual. ... | 03/04/2008 |
| 7335659 | Substituted 10-aryl-11-benzo[]fluorenes and 7-aryl-5, 6-dihydro-benzo[]anthracenes for selective effects on estrogen receptors This invention provides a compound, or its possible salt, having the formula, wherein: Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2CH2— or... | 02/26/2008 |
| 7326733 | Methods for increasing bone density Methods and compounds for remodeling bone and treating osteopenic conditions are described. Methods and compounds for increasing bone mineral density by decreasing serotonin levels in osteoblasts are also described. ... | 02/05/2008 |
| 7321065 | Thyronamine derivatives and analogs and methods of use thereof Thyronamine derivatives and analogs, methods of using such compounds, and pharmaceutical compositions containing them are disclosed. Methods of preparing such compounds are also disclosed. ... | 01/22/2008 |
| 7317023 | Diaryl ether β2 adrenergic receptor agonists The invention provides novel β2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with β2 adrenergic receptor... | 01/08/2008 |
| 7309497 | Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient i... | 12/18/2007 |
| 7297794 | Phenoxy amine compounds and compositions for delivering active agents Phenoxy amine compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 11/20/2007 |
| 7276503 | Method of treating chronic fatigue syndrome Disclosed herein are methods of treating an individual suffering from, chronic fatigue syndrome. The methods generally include administration of a therapeutic amount of optically pure (S,S) reboxetine, or a pharmaceutically acceptable salt thereof, to the individual... | 10/02/2007 |
| 7271197 | Phenethanolamine derivatives The present invention relates to novel compounds of formula (I), or a salt, solvate, or physiologically functional derivative thereof, to a process for their manufacture, to pharmaceutical compositions containing... | 09/18/2007 |
| 7268152 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof Compounds of Formula (IA) and Formula (IB) wherein R1, R2, R3, R4, R5, and R6 are as defined herein for Formula (IA) or Formula (IB), or a tautome... | 09/11/2007 |
| 7259188 | Methods and pharmaceutical compositions for treatment of anti-estrogen resistant breast cancer using RXR modulators Methods and compositions for the treatment of anti-estrogen resistant breast cancer using retinoid compounds which are modulators of Retinoid X Receptors. ... | 08/21/2007 |
| 7244769 | Methods for treating an impairment in memory consolidation Impairments in memory consolidation are treated with an amphetamine compound. In one embodiment, the method includes administering an l-amphetamine compound. In another embodiment, the method includes administering an l-methamphetamine compound. The method can inclu... | 07/17/2007 |
| 7244703 | Pharmaceutical compositions and methods for peptide treatment Compositions and methods for treating a patient with a pharmaceutically active peptide that combines a pharmaceutically active peptide, a permeation enhancer, and a carrier, are disclosed. ... | 07/17/2007 |
| 7241778 | Non-imidazole aryloxypiperidines Substituted non-imidazole aryloxypiperidine compounds, compositions containing them, and methods of making and using them to treat or prevent histamine-mediated conditions. ... | 07/10/2007 |
| 7241762 | Method of treating peripheral neuropathy Disclosed herein are methods of treating an individual suffering from peripheral neuropathy. The methods generally include administration of a therapeutic amount of racemic reboxetine, or a pharmaceutically acceptable salt thereof, to the individual. ... | 07/10/2007 |
