"Flight by machines heavier than air is unpractical and insignificant, if not utterly impossible."
Simon Newcomb, astronomer ; Said in 1902, less than two years before the first flight at Kitty Hawk
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| Number | Title | Issue Date |
| 8143314 | Methods and formulations for treating ineffective or decreased esophageal motility Pharmaceutical compositions and methods for treating ineffective esophageal motility in which bethanechol and pharmaceutically acceptable absorption enhancers comprising bile acids and mixtures thereof are topically introduced to the esophagus. Therapeutically effec... | 03/27/2012 |
| 7932291 | Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use The use of L-carnitine and its alkanoyl derivatives, optionally in the form of a pharmaceutically acceptable salt, as osmotic agents in the preparation of solutions for medical use, particularly for peritoneal dialysis, is described. ... | 04/26/2011 |
| 7932292 | Use of quaternary ammonium compounds in the remediation of mold, mildew, and funguses The present invention relates to the use of quaternary ammonium compounds in the remediation of microbial growth such as mold, funguses, and mildew. ... | 04/26/2011 |
| 7803842 | Choline esters useful for the treatment of cognitive dysfunctions and enhancement of memory, learning and cognition The present invention provides compounds of formula I described herein. The present invention also provides a method of treating a cognitive dysfunction in a mammal. The method includes administering to the mammal an effective amount of a compound of formula I descr... | 09/28/2010 |
| 7449494 | Polymeric skin moisturizing compounds The present invention is directed to a series of new cationic polymeric materials and a process for their use as moisturizing agents on skin. The polymers of the invention are made by the reaction of dimethyl ethanolamine, and tetra 2-hydroxyalkyl ethylene diamne wi... | 11/11/2008 |
| 7410958 | Triterpene quaternary salts as biologically active surfactants The invention provides novel compounds that are quaternary amine derivatives of betulin and other triterpenes. The compounds have antibacterial, antifungal, and surfactant properties. ... | 08/12/2008 |
| 7407979 | Bioregulatory active ingredient combination The present invention relates to the use of specific quaternized bioregulatory active ingredients in combination with triazole derivatives, in particular metconazole or an agriculturally utilizable salt thereof. Corresponding compositions are likewise described.... | 08/05/2008 |
| 7390821 | Methods of reducing angiogenesis The present invention provides methods of reducing angiogenesis in an individual. The methods generally involve administering to the individual an effective amount of a nicotinic acetyl choline receptor antagonist. The methods are useful to treat conditions associat... | 06/24/2008 |
| 7381521 | Anti-pathogenic composition useful in blood preservation The present invention includes a method for reducing viral, bacterial, protozoan, fungal and other parasitic contamination from a biological solution. Biological solutions include, but are not limited to, solutions comprising blood, a blood component, cell culture o... | 06/03/2008 |
| 7364746 | Liquid concentrate for the preservation of cosmetic and pharmaceutical products The invention relates to a liquid concentrate for the preservation of cosmetic and pharmaceutical products which comprises 3-iodo-2-propynyl butylcarbamate (IPBC), at least one liquid carrier selected from the group consisting of: polyvalent alcohols, glycol esters ... | 04/29/2008 |
| 7323594 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/29/2008 |
| 7314959 | Amino thiol compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine and amino thiol compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-ef... | 01/01/2008 |
| 7314624 | Nanoemulsion vaccines The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental... | 01/01/2008 |
| 7312244 | Polyamine analog-amino acid conjugates useful as anticancer agents Conjugates in which polyamine analogs are conjugated to an amino acid are provided, as well as compositions comprising these conjugates. Methods of using these conjugates as anticancer treatments are also provided. ... | 12/25/2007 |
| 7294621 | Lipid analogs for combating tumors The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294620 | Lipid analogs for inhibiting HIV-1 activity The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7294619 | Lipid analogs for inhibiting the activity of hepatitis B antigen The invention relates to methods of treating viral infections, and in particular hepatitis B virus. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative to inhibit the ... | 11/13/2007 |
| 7282470 | Decontamination formulation with sorbent additive A decontamination formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The formulation provides so... | 10/16/2007 |
| 7279502 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions... | 10/09/2007 |
| 7268163 | Method for treating an inflammation or lesion caused by a virus A method for treating an inflammation or lesion caused by herpesvirus, comprising topically applying to said inflammation or lesion a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust... | 09/11/2007 |
| 7268165 | Enhanced activity alcohol-based antimicrobial compositions Antimicrobial compositions which can be used wherever disinfecting compositions are needed, such as in a hospital, healthcare industry, workplace, recreational facility, home or similar environment. The antimicrobial compositions are particularly useful as a topical... | 09/11/2007 |
| 7261880 | Methods of treating Syndrome X with aliphatic polyamines The invention relates to a method for treating Syndrome X, or inhibiting the onset of symptoms of Syndrome X in a patient, and includes administering a therapeutically effective amount of a salt of at least one alkylated and cross-linked polymer, or a copolymer ther... | 08/28/2007 |
| 7246628 | Method for cleaning floor drains A method for controlling Listeria in floor drains wherein an aqueous solution composed of a chlorinated caustic material which is soft metal compatible is introduced into a drain where Listeria is present. In a preferred manner, the aqueous solution is... | 07/24/2007 |
| 7226609 | Sodium dodecyl sulfate compositions for inactivating prions An antiseptic composition useful in destroying the infectivity of infectious proteins such as prions is disclosed. The antiseptic composition is preferably maintained at either a low pH of 4.0 or less or a high pH of 10.0 or more either of which allows for an enviro... | 06/05/2007 |
| 7202280 | Methods for the treatment and prevention of pancreatitis and for induction of liver regeneration Novel methods for treating and preventing acute and/or chronic pancreatitis are described. Additionally, novel methods for inducing liver regeneration are described. The methods may comprise administering to a patient an effective amount of a metabolically stable an... | 04/10/2007 |
| 7199114 | Triterpene quaternary salts as biologically active surfactants The invention provides novel compounds that are quaternary amine derivatives of betulin and other triterpenes. The compounds have antibacterial, antifungal, and surfactant properties. ... | 04/03/2007 |
| 7193111 | Dimer poly-quaternary compounds The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid reacted with an dimethyl amino propyl amine to make an amido amine, which is subsequently reacted to make a polymeric quaternary compound.... | 03/20/2007 |
| 7189874 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting of N, O and S... | 03/13/2007 |
| 7189865 | Thiomolybdate analogues and uses thereof The current invention provides novel thiomolybdate derivatives, methods of making novel thiomolybdate derivatives, pharmaceutical compositions of novel thiomolybdate derivatives, methods of using novel thiomolybdate derivatives to treat diseases associated with aber... | 03/13/2007 |
| 7172879 | Detection of sphingosine kinase activity and sphingosine kinase agonist or antagonist activity The invention relates to detection of sphingosine kinase activity and sphingosine kinase agonist or antagonist activity. ... | 02/06/2007 |
| 7173154 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 02/06/2007 |
| 7166745 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 01/23/2007 |
| 7147859 | Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers It relates to an Association of chemical agents, with intended pharmacological action to prevent the risk of infarction and brain hemorrhage caused by the development of the atherosclerotic process and of the homocysteinemia resulting from ageing. It is of th... | 12/12/2006 |
| 7145039 | Transfection reagents Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the gro... | 12/05/2006 |
| 7141557 | Lipid analogs for treating viral infections A method of treating viral infections, and in particular HIV-1, hepatitis B virus, and herpes virus, is disclosed. The method comprises administering to a subject in need of such treatment an infection-controlling amount of a phospholipid or phospholipid derivative.... | 11/28/2006 |
| 7132448 | High concentration topical insecticide containing insect growth regulator A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. The insecticide contains an insecticide and an insect growth regulator effective for killing fleas, flea larvae and flea ... | 11/07/2006 |
| 7125497 | Reactive formulations for a neutralization of toxic industrial chemicals Decontamination formulations for neutralization of toxic industrial chemicals, and methods of making and using same. The formulations are effective for neutralizing malathion, hydrogen cyanide, sodium cyanide, butyl isocyanate, carbon disulfide, phosgene gas, capsai... | 10/24/2006 |
| 7122505 | Composition for controlling the growth of algae, fungi and pathogenic organisms in water A stable aqueous concentrate comprising a polymeric biguanide, a chelating agent and a water-miscible organic solvent for controlling the growth of algae, fungi and pathogenic organisms in water. ... | 10/17/2006 |
| 7105574 | Adjuvant compositions and methods for enhancing immune responses to polynucleotide-based vaccines The invention provides adjuvants, immunogenic compositions, and methods useful for polynucleotide-based vaccination and immune response. In particular, the invention provides an adjuvant of cytofectin:co-lipid mixture wherein cytofectin is GAP-DMORIE. ... | 09/12/2006 |
| 7097861 | Method of treating livestock footbath solutions This invention relates to a method of treating a livestock footbath solution comprising adding an alkali metal bisulfate to the solution. The invention also relates to a method of treating a livestock footbath solution comprising adding to the solution a blend of an... | 08/29/2006 |