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Class 514/619 - Nitrogen in R


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the carboxylic acid residue (R) also
No. of patents: 555
Last issue date: 03/06/2012


                    14  
NumberTitleIssue Date
42541463-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters
3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters are disclosed having the formula: ##STR1## wherein R1 is hydrogen or lower alkyl; R2 is OH, OM, O-lower alkyl, NH2, NH-lower alkyl or N,N-dilower alk...
03/03/1981
4221807Alkanolamine derivatives
Novel 1-heterocyclyloxy-or 1-aryloxy-3-amidoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess ଲ-adrener...
09/09/1980
4219561Alkanolamine derivatives
1-Aryloxy-3-(tri- or tetra-acylamido)-alkylamino-propan-2-ol derivatives, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess ଲ-adrenergic blocking activity and are useful in the treatment of heart ...
08/26/1980
4218478Trichostatin as an antiprotozoal agent
Trichostatin (I) is disclosed to be useful as an antiprotozoal agent for the treatment of diseases in man and animals. Also disclosed are pharmaceutical compositions comprising trichostatin for treating protozoal infections. Trichostatin has the structure...
08/19/1980
4215114Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]b e
Cis - and trans-N-(2-aminocycycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-[(2-furylmethyl)methylamino]-cyclohexyl]-3,4-dichlorobenzami de, and their pharmaceutically acceptable salts, have been found to have ...
07/29/1980
4212878Phenylacetamide derivative analgesics
N-[(1-Amino-4-(mono or di-oxygen-group-substituted)cyclohex-1-yl)methyl]phenylacetamide derivatives of the formula 1 ##STR1## wherein R, R1, R2, R3, P, Q, X and Y are defined in the specification, e.g., 2-(3...
07/15/1980
4192885Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity,...
03/11/1980
4190668Stabilized aqueous amide antimicrobial composition
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene glycol (e.g., polyethylene glycol 200) or an ether thereof ...
02/26/1980
4175135Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof
A method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animals an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound and alkali metal salts, ammonium salts and enol ester derivative th...
11/20/1979
4163798Stabilized aqueous amide antimicrobial composition
Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene glycol (e.g., polyethylene glycol 200) or an ether thereof ...
08/07/1979
4158063Acylamino(alkyl)benzene derivatives and process for preparing them
The invention relates to acylamino(alkyl)benzene derivatives of the general formula ##STR1## in which W represents a group which can be converted into a carboxyl group, or an aldehyde group or an oxymethyl group or their derivatives or also a lo...
06/12/1979
4153717Analgesic N-(2-(furylmethylamino and 2 -thienylmethylamino)cyclo aliphatic)benzamides
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-[(2-furylmethyl)methylamino]cyclohexyl]-3,4-dichlorobenzamid e, and their pharmaceutically acceptable salts, have been found to have potent an...
05/08/1979
4152459Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides
Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their parmaceutically acceptable salts, have been found to have potent analgesic activity, ...
05/01/1979
4151297Bicyclo [3.1.0] hexyl-substituted ethylamino carbonyl phenoxy cardiovascular agents
1-Alkylamino-3-(3- or 4-[2-(endobicyclo[3.1.0]-hex-6-yl)ethylaminocarbonyl]-1-phenoxy)-2-propano l and substituted derivatives thereof and methods for preparing such compounds are disclosed. 5-(3- Or 4-[2-(endobicyclo[3.1.0]hex-6-yl)ethylaminocarbonyl...
04/24/1979
4151125Biocidal additive for cutting fluids
The addition of a 2-mercaptobenzamide to cutting fluid prevents bacterial and fungal growth. Concentrated solutions thereof in certain organic solvents are also disclosed. One such solution provides additional protection against corrosion of the metal sur...
04/24/1979
4130661Substituted benzoylacrylanilides
Novel substituted benzoylacrylanilides are prepared by reacting a substituted benzoylacrylic acid with a substituted aniline in the presence of a coupling agent. These acrylanilides have significant anticoccidial activity....
12/19/1978
4094973Medical protein hydrolysate and process of using the same
Medical protein hydrolysate is produced from the feet of young freshly killed poultry. The protein, thus produced, is an extract of polypeptides and amino acids. It is in the form of a powder or a gel, each of which is suitable for topical application to ...
06/13/1978
4092430Antiphlogistic phenylacetohydroxamic acid compositions
Phenylacetohydroxamic acids having the formula I ##STR1## wherein R1, R2, R3 and R4, independently of each other, represent hydrogen, chlorine, fluorine or bromine atoms or an alkyl or alkoxy group having a...
05/30/1978
4084002Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
Pharmaceutical dosage unit compositions containing as an active ingredient a 1-aryloxy-2-hydroxy-3-alkynylamino-propane selected from the group consisting of racemic or optically active compounds of the formula ##STR1## wherein R1 is a mem...
04/11/1978
4073940Method for treating cardiac arhythmia by administration of basic aryloxyacetamide
New method for treating cardiac arhythmia by administering to a patient N-(2,5-diethoxy phenyl)-N-(2-diethylamino ethyl)-4-butoxyphenoxy acetamide or a pharmaceutically acceptable acid addition salt thereof....
02/14/1978
4066747Polymeric orthoesters housing beneficial drug for controlled release therefrom
This invention concerns polymeric orthoesters having a repeating mer comprising a hydrocarbon radical and an orthoester functionality of the general formula: ##STR1## wherein R1 is a monovalent radical, R2 is a hydrocarbon radic...
01/03/1978
4065559Dinitroanilines for control of soil-borne phytopathogens
A class of 2,6-dinitroanilines having a broad range of substituent groups on the anilino nitrogen and in the 3- and 4-positions of the phenyl ring are used for the protection of plants against soil-borne phytopathogens of the genus Phytophthora....
12/27/1977
4060638Anthranilic acid amides
Derivatives of trifluoromethyl-substituted anthranilic acid amides, e.g., N-methyl-o-amino-଱,଱,଱-trifluoromethyl-p-toluamide, are useful as minor tranquilizers and muscle relaxants....
11/29/1977
4051259Phenoxyacetic acid amide
The invention relates to 1-methyl-2-(m-trifluoromethylphenyl)-ethylamide of p-pentylaminophenoxyacetic acid and its pharmaceutically acceptable acid addition salts which have outstanding anorexigenic properties....
09/27/1977
4034112Ethanolamine derivatives having ଲ-adrenergic blocking activity
Novel 1-aryl-2-amidoalkylaminoethanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess ଲ-adrenergic blocking activity. Repre...
07/05/1977
4027021Interferon induction
A method and therapeutic compositions for inducing interferon formation in vivo. To a host is administered an interferon inducer selected from the group consisting of A. 1,5-bis[(3-morpholinopropyl)amino]anthraquinone, B. 1-[(2-aminoethyl)amino]-5-[[1-(hydroxy...
05/31/1977
4016287Dermatological compositions containing an acylamino-carboxylic acid or an alkyl ester thereof
Topical dermatological compositions containing an acylamino-carboxylic acid compound of the formula ##STR1## wherein R1 is hydrogen, alkyl of 1 to 3 carbon atoms, trifluoromethyl, phenyl, halo-phenyl, nitro-phenyl or biphenylyl, R2
04/05/1977
4004008O-Tertiary amino-alkyl-N-benzoyl tyrosil amides
Tyrosine derivatives of the formula: ##STR1## wherein: R1 is a linear or branched-chain alkyl group having 1-6 carbon atoms, terminating by a tertiary amino group; R.sub. 2 is an unsubstituted, monosubstituted or di-substituted phenyl or b...
01/18/1977
4004029Compositions and method for treating epilepsy and convulsions
Compounds of the formula ##STR1## wherein R1 and R2 are each hydrogen or lower alkyl, R3 represents lower alkyl and A is a monovalent group of formula: ##STR2## wherein Y is hydrogen or the acyl radical of a hydr...
01/18/1977
3976785Dioxocyclohexanecarboxanilide insecticides and acaricides
The present invention relates to certain carboxanilide insecticidal and acaricidal methods and compositions. It further relates to certain carboxanilides employed as active ingredients therein....
08/24/1976
3969510Method of controlling fungi
Method of controlling fungi with substituted benzoic acid derivatives, in particular substituted benzanilides....
07/13/1976
3961072Phenoxypropanolamine therapeutic agents
A series of novel substituted phenoxypropylamine derivatives have been prepared by reacting the appropriate 1-phenoxy-2,3-epoxypropane compound with a suitable organic amine reagent. The resulting 1-phenoxy-3-alkylaminopropan-2-ols are useful in the field...
06/01/1976
3950539Substituted diaminoguanidines
Substituted diamino-guanidines are described as well as their manufacture and their use as medicaments against protozoa, especially against coccidiosis....
04/13/1976
3949088Substituted phenoxy propanol amines used for treating cardiovascular diseases
A new amine of the formula ##EQU1## wherein R1 is loweralkylthio loweralkyl, loweralkoxy loweralkoxy, loweralkylcarbonylamino loweralkyl or loweralkoxycarbonylamino loweralkyl, R2 is benzyl, phenoxyloweralkyl, cyano or the group...
04/06/1976
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