"That the automobile has practically reached the limit of its development is suggested by the fact that during the past year no improvements of a radical nature have been introduced."
Scientific American ; Jan. 2 edition, 1909
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| Number | Title | Issue Date |
| 4254146 | 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters are disclosed having the formula: ##STR1## wherein R1 is hydrogen or lower alkyl; R2 is OH, OM, O-lower alkyl, NH2, NH-lower alkyl or N,N-dilower alk... | 03/03/1981 |
| 4221807 | Alkanolamine derivatives Novel 1-heterocyclyloxy-or 1-aryloxy-3-amidoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess ଲ-adrener... | 09/09/1980 |
| 4219561 | Alkanolamine derivatives 1-Aryloxy-3-(tri- or tetra-acylamido)-alkylamino-propan-2-ol derivatives, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess ଲ-adrenergic blocking activity and are useful in the treatment of heart ... | 08/26/1980 |
| 4218478 | Trichostatin as an antiprotozoal agent Trichostatin (I) is disclosed to be useful as an antiprotozoal agent for the treatment of diseases in man and animals. Also disclosed are pharmaceutical compositions comprising trichostatin for treating protozoal infections. Trichostatin has the structure... | 08/19/1980 |
| 4215114 | Analgesic N-[2-(furyl-methylamino and 2-thienylmethylamino)cycloaliphatic]b e Cis - and trans-N-(2-aminocycycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-[(2-furylmethyl)methylamino]-cyclohexyl]-3,4-dichlorobenzami de, and their pharmaceutically acceptable salts, have been found to have ... | 07/29/1980 |
| 4212878 | Phenylacetamide derivative analgesics N-[(1-Amino-4-(mono or di-oxygen-group-substituted)cyclohex-1-yl)methyl]phenylacetamide derivatives of the formula 1 ##STR1## wherein R, R1, R2, R3, P, Q, X and Y are defined in the specification, e.g., 2-(3... | 07/15/1980 |
| 4192885 | Analgesic N-{2-[N'-(2-furylmethyl and 2-thienyl-methyl)-N'-alkylamino]cycloaliphatic}cyanobenzamides Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their pharmaceutically acceptable salts, have been found to have potent analgesic activity,... | 03/11/1980 |
| 4190668 | Stabilized aqueous amide antimicrobial composition Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene glycol (e.g., polyethylene glycol 200) or an ether thereof ... | 02/26/1980 |
| 4175135 | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof A method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animals an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound and alkali metal salts, ammonium salts and enol ester derivative th... | 11/20/1979 |
| 4163798 | Stabilized aqueous amide antimicrobial composition Aqueous antimicrobial compositions which comprise a halogenated amide antimicrobial, such as 2,2-dibromonitrilopropionamide, a water miscible organic solvent such as a straight chain polyalkylene glycol (e.g., polyethylene glycol 200) or an ether thereof ... | 08/07/1979 |
| 4158063 | Acylamino(alkyl)benzene derivatives and process for preparing them The invention relates to acylamino(alkyl)benzene derivatives of the general formula ##STR1## in which W represents a group which can be converted into a carboxyl group, or an aldehyde group or an oxymethyl group or their derivatives or also a lo... | 06/12/1979 |
| 4153717 | Analgesic N-(2-(furylmethylamino and 2 -thienylmethylamino)cyclo aliphatic)benzamides Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-[(2-furylmethyl)methylamino]cyclohexyl]-3,4-dichlorobenzamid e, and their pharmaceutically acceptable salts, have been found to have potent an... | 05/08/1979 |
| 4152459 | Analgesic N-2-(aminocycloaliphatic)-hydroxy, alkoxy and (allylic)alkenyloxy-benzamides Cis- and trans-N-(2-aminocycloaliphatic)benzamide compounds of the formula ##STR1## e.g., N-methyl-N-[2-(N-pyrrolidinyl)cyclohexyl]-3,4-dichlorobenzamide, and their parmaceutically acceptable salts, have been found to have potent analgesic activity, ... | 05/01/1979 |
| 4151297 | Bicyclo [3.1.0] hexyl-substituted ethylamino carbonyl phenoxy cardiovascular agents 1-Alkylamino-3-(3- or 4-[2-(endobicyclo[3.1.0]-hex-6-yl)ethylaminocarbonyl]-1-phenoxy)-2-propano l and substituted derivatives thereof and methods for preparing such compounds are disclosed. 5-(3- Or 4-[2-(endobicyclo[3.1.0]hex-6-yl)ethylaminocarbonyl... | 04/24/1979 |
| 4151125 | Biocidal additive for cutting fluids The addition of a 2-mercaptobenzamide to cutting fluid prevents bacterial and fungal growth. Concentrated solutions thereof in certain organic solvents are also disclosed. One such solution provides additional protection against corrosion of the metal sur... | 04/24/1979 |
| 4130661 | Substituted benzoylacrylanilides Novel substituted benzoylacrylanilides are prepared by reacting a substituted benzoylacrylic acid with a substituted aniline in the presence of a coupling agent. These acrylanilides have significant anticoccidial activity.... | 12/19/1978 |
| 4094973 | Medical protein hydrolysate and process of using the same Medical protein hydrolysate is produced from the feet of young freshly killed poultry. The protein, thus produced, is an extract of polypeptides and amino acids. It is in the form of a powder or a gel, each of which is suitable for topical application to ... | 06/13/1978 |
| 4092430 | Antiphlogistic phenylacetohydroxamic acid compositions Phenylacetohydroxamic acids having the formula I ##STR1## wherein R1, R2, R3 and R4, independently of each other, represent hydrogen, chlorine, fluorine or bromine atoms or an alkyl or alkoxy group having a... | 05/30/1978 |
| 4084002 | Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use Pharmaceutical dosage unit compositions containing as an active ingredient a 1-aryloxy-2-hydroxy-3-alkynylamino-propane selected from the group consisting of racemic or optically active compounds of the formula ##STR1## wherein R1 is a mem... | 04/11/1978 |
| 4073940 | Method for treating cardiac arhythmia by administration of basic aryloxyacetamide New method for treating cardiac arhythmia by administering to a patient N-(2,5-diethoxy phenyl)-N-(2-diethylamino ethyl)-4-butoxyphenoxy acetamide or a pharmaceutically acceptable acid addition salt thereof.... | 02/14/1978 |
| 4066747 | Polymeric orthoesters housing beneficial drug for controlled release therefrom This invention concerns polymeric orthoesters having a repeating mer comprising a hydrocarbon radical and an orthoester functionality of the general formula: ##STR1## wherein R1 is a monovalent radical, R2 is a hydrocarbon radic... | 01/03/1978 |
| 4065559 | Dinitroanilines for control of soil-borne phytopathogens A class of 2,6-dinitroanilines having a broad range of substituent groups on the anilino nitrogen and in the 3- and 4-positions of the phenyl ring are used for the protection of plants against soil-borne phytopathogens of the genus Phytophthora.... | 12/27/1977 |
| 4060638 | Anthranilic acid amides Derivatives of trifluoromethyl-substituted anthranilic acid amides, e.g., N-methyl-o-amino-,,-trifluoromethyl-p-toluamide, are useful as minor tranquilizers and muscle relaxants.... | 11/29/1977 |
| 4051259 | Phenoxyacetic acid amide The invention relates to 1-methyl-2-(m-trifluoromethylphenyl)-ethylamide of p-pentylaminophenoxyacetic acid and its pharmaceutically acceptable acid addition salts which have outstanding anorexigenic properties.... | 09/27/1977 |
| 4034112 | Ethanolamine derivatives having ଲ-adrenergic blocking activity Novel 1-aryl-2-amidoalkylaminoethanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess ଲ-adrenergic blocking activity. Repre... | 07/05/1977 |
| 4027021 | Interferon induction A method and therapeutic compositions for inducing interferon formation in vivo. To a host is administered an interferon inducer selected from the group consisting of A. 1,5-bis[(3-morpholinopropyl)amino]anthraquinone, B. 1-[(2-aminoethyl)amino]-5-[[1-(hydroxy... | 05/31/1977 |
| 4016287 | Dermatological compositions containing an acylamino-carboxylic acid or an alkyl ester thereof Topical dermatological compositions containing an acylamino-carboxylic acid compound of the formula ##STR1## wherein R1 is hydrogen, alkyl of 1 to 3 carbon atoms, trifluoromethyl, phenyl, halo-phenyl, nitro-phenyl or biphenylyl, R2 | 04/05/1977 |
| 4004008 | O-Tertiary amino-alkyl-N-benzoyl tyrosil amides Tyrosine derivatives of the formula: ##STR1## wherein: R1 is a linear or branched-chain alkyl group having 1-6 carbon atoms, terminating by a tertiary amino group; R.sub. 2 is an unsubstituted, monosubstituted or di-substituted phenyl or b... | 01/18/1977 |
| 4004029 | Compositions and method for treating epilepsy and convulsions Compounds of the formula ##STR1## wherein R1 and R2 are each hydrogen or lower alkyl, R3 represents lower alkyl and A is a monovalent group of formula: ##STR2## wherein Y is hydrogen or the acyl radical of a hydr... | 01/18/1977 |
| 3976785 | Dioxocyclohexanecarboxanilide insecticides and acaricides The present invention relates to certain carboxanilide insecticidal and acaricidal methods and compositions. It further relates to certain carboxanilides employed as active ingredients therein.... | 08/24/1976 |
| 3969510 | Method of controlling fungi Method of controlling fungi with substituted benzoic acid derivatives, in particular substituted benzanilides.... | 07/13/1976 |
| 3961072 | Phenoxypropanolamine therapeutic agents A series of novel substituted phenoxypropylamine derivatives have been prepared by reacting the appropriate 1-phenoxy-2,3-epoxypropane compound with a suitable organic amine reagent. The resulting 1-phenoxy-3-alkylaminopropan-2-ols are useful in the field... | 06/01/1976 |
| 3950539 | Substituted diaminoguanidines Substituted diamino-guanidines are described as well as their manufacture and their use as medicaments against protozoa, especially against coccidiosis.... | 04/13/1976 |
| 3949088 | Substituted phenoxy propanol amines used for treating cardiovascular diseases A new amine of the formula ##EQU1## wherein R1 is loweralkylthio loweralkyl, loweralkoxy loweralkoxy, loweralkylcarbonylamino loweralkyl or loweralkoxycarbonylamino loweralkyl, R2 is benzyl, phenoxyloweralkyl, cyano or the group... | 04/06/1976 |