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| Number | Title | Issue Date |
| 8426386 | NK1 receptor antagonist composition An NK1 receptor antagonist composition of the present invention uses maltooligosaccharide having an NK1 receptor antagonistic activity as an active ingredient. A suitable amount of the maltooligosaccharide to be blended in the NK1 receptor antagonist composition of ... | 04/23/2013 |
| 8372808 | Suppression of glial fibrillary acidic protein Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell. Also provided are compounds useful for the treatment of Alexander disea... | 02/12/2013 |
| 8367641 | Use of modified oligo-β-(1,3)-glucans for treating diseases of the immune system, oligo-β-(1,3)-glucan-(1,3)-mannose, oligo-β-(1,3)-glucan-(1,3)-mannitol and derivatives thereof, methods for preparing them and medicaments containing them The present invention relates to the use of at least one compound of formula (I) or (II), in which R1 is H and n is an integer from 2 to 10, for the preparation of a medicament for treating diseases chosen from the group comprising tumour, cancer, viral d... | 02/05/2013 |
| 8314079 | Hyaluronic acid oligosaccharide fractions and drugs containing the same A method for promoting expression of a heat shock protein, or for inhibiting cell injury or cell death, or for treating a disease for which cell or tissue protection is desired, or for promoting production of IL-10, or for inhibiting production of IL-8, by administe... | 11/20/2012 |
| 8288364 | Botanically derived composition and a process thereof The present invention relates to a novel botanical compound as provided in structural formula I optionally along with excipients for improving body composition and the factors related to the pre-diabetic and diabetic conditions. It also relates to a process of manuf... | 10/16/2012 |
| 8153614 | Treatment of osteoarthritis There is provided a therapeutic agent for treating osteoarthritis, which is a drug comprising hyaluronan as an active ingredient. The hyaluronan is preferably a tetrasaccharide including two units, with a single unit being -D-glucuronic acid-β-1,3-D-N-acetylglucosa... | 04/10/2012 |
| 7998943 | Core 2 GlcNAc-T inhibitors III A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective amount of an inhibitor of core 2 GlcNAc-T of the formula I to a patie... | 08/16/2011 |
| 7994155 | Accelerator for mineral absorption and use thereof The present invention has an object to provide an accelerator for mineral absorption and a composition containing the accelerator. The object is solved by providing an accelerator for mineral absorption comprising cyclic tetrasaccharide and/or saccharide derivatives... | 08/09/2011 |
| 7915235 | High affinity ligands bind to clostridium difficile toxin A Glycans are identified which have high affinity for C. difficile toxin A. They share one of two saccharide backbones and may have additional side chains. The backbones are galactose-β1-3 N-acetyl-D-glucosamine-β-1-3-galactose-β-1-4-N-acetyl-D-glucosamine a... | 03/29/2011 |
| 7906493 | Core 2 GlcNAc-T inhibitors Method of treating conditions associated with raised activity of core 2 GlcNAc-T by administering an inhibitor of UDP-GlcNAc:Galβ1,3GalNAc-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyl transferase (core 2 β1,6 N-acetylaminotransferase, core 2 GlcNAc-T-EC 2.4.1.1... | 03/15/2011 |
| 7476660 | Composition and method for organ preservation The present invention relates to a composition for organ preservation, comprising an inulin type fructan as an active ingredient. The composition for organ preservation can suppress the hypofunction of an organ and damage to a histological structure and can improve ... | 01/13/2009 |
| 7417031 | Use of algae-derived physiologically active substances for treating a carcinomatous disease Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least... | 08/26/2008 |
| 7402575 | Methods of treating inflammation Methods and compositions for treating myocardial dysfunction or inflammation are described. The methods of the invention involve administering an agent that can inhibit lysozyme to an animal in need thereof. Preferred lysozyme inhibitors include TAC and chitobiose. | 07/22/2008 |
| 7375095 | Sugar derivative For extending the uses of a compound represented by Chemical formula 1, the object of the present invention is to provide a derivative of cyclic tetrasaccharide whose physicochemical properties are changed from those of cyclic tetrasaccaride, a composition comprisin... | 05/20/2008 |
| 7365192 | Preparation method of valienamine from acarbose and/or acarbose derivatives using trifluoroacetic acid The present invention provides a preparation method of valienamine from acarbose or acarbose derivatives using organic acid TFA (trifluoroacetic acid). By using the method of the present invention, valienamine, the core precursor of voglibose which is a strong retar... | 04/29/2008 |
| 7365191 | Type of oligosaccharides and their sulfate derivatives This invention involves a type of oligosacoharides and its their sulfate derivatives. The backbone of the oligosaccharides consists of 4 to 14 glucose residues, while the side chains contain 0 to 4 glucose residues. There are at least one 1->3α linkage and β-(1->3... | 04/29/2008 |
| 7361644 | Specific antagonist for both E- and P-selectins Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 04/22/2008 |
| 7361744 | Oligosaccharide derivative Compounds having the formula (I): wherein A represents a group such as a cyclic group, R1 and R2 represent groups such as alkyl groups or hydroxymethyl groups, and n represents 1 or 2, or pharmacologic... | 04/22/2008 |
| 7326182 | Method of using device for bio-affinity material for treatment of blood or plasma Bio-affinity material containing at least one biologically active saccharide which is covalently bound via at least one spacer to a cross-linked matrix and that the material is autoclaved. Apparatus for contacting body fluids with the bio-affinity material is disclo... | 02/05/2008 |
| 7309697 | Cyclic maltosylmatose An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for produci... | 12/18/2007 |
| 7297680 | Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content Disclosed are immortalized human embryonic retina cells, having a nucleic acid sequence encoding an adenoviral E1A protein integrated into the genome of the cells, and further comprising a nucleic acid sequence encoding an enzyme involved in post-translational modif... | 11/20/2007 |
| 7291607 | Isomaltooligosaccharides from as neutraceuticals Isomaltooligosaccharides (IMOs) produced by Leuconostoc mesenteroides ATCC 13146 fermentation with a sucrose:maltose ratio of 2:1 have been discovered to be effective prebiotics in mixed cultures of microbial populations, including cultures from chicken ceca.... | 11/06/2007 |
| 7271158 | Treatment of rumen acidosis with α-amylase inhibitors The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of acidosis; a method of treatment of rumen acidosis which comprises administration of ... | 09/18/2007 |
| 7238677 | Prevention of urogenital infections The invention provides hyaluronic acid compounds and derivatives thereof for preventing urogenital infections by a variety of pathogens, as well as compositions, articles and methods for treating and preventing urogenital infections. ... | 07/03/2007 |
| 7192937 | Oligosaccharide-containing compositions and uses thereof The use of compositions containing one or more oligosaccharides in an amount effective to disinfect and/or preserve medical devices, pharmaceutical preparations, and the like is described. Buffered solutions containing one or more oligosaccharide-containing composit... | 03/20/2007 |
| 7182954 | Prebiotic oligosaccharides via alternansucrase acceptor reactions Oligosaccharides produced by an alternansucrase enzyme catalyzed reaction of sucrose with an acceptor oligosaccharide are effective as prebiotics for controlling enteric bacterial pathogens. Populations of enteropathogenic bacteria may be substantially reduced or in... | 02/27/2007 |
| 7166582 | Antiallergic composition The present invention provides a sate and excellent antiallergic composition, and more particularly a preventive and therapeutic composition for atopic dermatitis, including an antiallergic composition blended with stachyose as an effective ingredient, and a medicin... | 01/23/2007 |
| 7163672 | Pharmaceutical aerosol formulation The invention relates to a pharmaceutical aerosol formulation comprising a surfactant that is an alkyl-polyglycoside of formula I, wherein DP is the average degree of polymerisation and has a value of from 1 to 4, and R is an alkyl chain or a mixture of alkyl chains... | 01/16/2007 |
| 7157431 | Compositions of plant carbohydrates as dietary supplements Compositions of plant carbohydrates for dietary supplements and nutritional support for promotion and maintenance of good health. Defined nutritionally effective amounts of one to eleven essential saccharides, glyconutrients, are used in various inventive compositio... | 01/02/2007 |
| 7148200 | Method for treating cancer A method for treating a cancer. The cancer excluding an adenocarcinoma and being epithelioma, glioma, sarcoma, melanoma, lymphoma or leukemia; or the cancer is an adenocarcinoma cancer excluding colon cancer, lung cancer and gastric cancer. The method comprises admi... | 12/12/2006 |
| 7119079 | Bioadhesive pharmaceutical compositions Disclosed are compounds having the formula wherein R2 is hydrogen, a monomeric glycoside or an oligomeric glycoside, R3 is hydrogen, a monomeric glycoside, an oligomeric glycoside, or a grou... | 10/10/2006 |
| 7109182 | Synthetic oligomannosides, preparation and uses thereof A pharmaceutical composition including a therapeutically effective amount of at least one oligomannoside produced by chemical synthesis which is homologous to a wall oligomannoside of an infectious organism or pathogen, or a derivative thereof, and a pharmaceuticall... | 09/19/2006 |
| 7105178 | Cardiotonic composition A cardiotonic composition includes micronized digoxin, hydrophilic polymer(s) and optionally pharmaceutically acceptable excipient(s) in the form of a tablet that releases not more than 50% digoxin in 5 minutes and at least 85% digoxin in 60 minutes. ... | 09/12/2006 |
| 7101859 | Use of lipid conjugates in the treatment of diseases The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomer... | 09/05/2006 |
| RE39245 | Galactopyranosides and their use The present invention relates to simplified synthesis, new carbohydrate-based products and practical use of different carbohydrate-based products. Examples of these are (Galα1-3Gal), GlcNAcβ1-3Gal, α- or β-glycosides thereof, Galα1-3Gal- containing tri-, or hig... | 08/22/2006 |
| 7070778 | Therapeutical combination against cancer The present invention relates to compositions and methods for treating humans and warm-blood animals suffering from cancer. More particularly, a therapeutical treatment in which a monoclonal antibody is administered with either β-(1,3)-glucan like laminarin or a ol... | 07/04/2006 |
| 7060685 | Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 06/13/2006 |
| 7056678 | Polysaccharide structure and sequence determination The invention provides a method for the structural analysis of a saccharide, comprising: a) providing on a surface a plurality of essentially sequence- and/or site-specific binding agents; b) contacting said surface with a saccharide to be analyzed, or with a mixtur... | 06/06/2006 |
| 7041656 | Sulfated fucoglucuronomannan An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fu... | 05/09/2006 |
| 7034006 | Use of lipid conjugates in the treatment of disease The invention provides novel methods for treating disease based upon the medicinal use of lipids and phospholipids covalently bound to physiologically acceptable monomers or polymers. Phosphatidylethanolamine moieties conjugated to physiologically acceptable monomer... | 04/25/2006 |
