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Patent No. 6099319

Neuroimaging as a Marketing Tool

Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.

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Class 514/585 - Benzene ring containing


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the compound contains a benzene ring.
No. of patents: 89
Last issue date: 04/13/2010


1      
NumberTitleIssue Date
7696249Diphenyl urea derivatives
The invention relates to novel specifically trifluoromethyl and halogen substituted 1,3-diphenyl ureas and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects like the preparation of the comp...
04/13/2010
7329670Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
The compounds are aryl and heteroaryl substituted heterocyclic ureas of the formula A—NH—C(O)—NH—B where A is the aryl or hetaryl substituted heterocyclic group and B is an aryl or heteroaryl moiety. The compounds inhibit raf kinase and are useful in the tre...
02/12/2008
7323496Compounds for treatment of inflammation, diabetes and related disorders
Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering b...
01/29/2008
7265136Substituted stilbene compounds with vascular damaging activity
A compound for use in inducing necrosis in vascular tissue of a tumor in an animal. The compound contains a first moiety which is a cis-stilbene moiety and a second moiety which is an inhibitor of the formation or action of nitric acid. Also, a method for inducing n...
09/04/2007
7262220Urea- and urethane-substituted acylureas, process for their preparation and their use
The invention relates to urea- and urethane-substituted acylureas and to their physiologically tolerated salts and physiologically functional derivatives. In particular, the invention relates to the compounds of the formula I
08/28/2007
7232897Compositions and methods for modulating NH2-terminal Jun Kinase activity
Disclosed herein are compositions and methods used to modulate a NH2-terminal Jun Kinase activity. These compositions and methods can be employed to regulate metabolic disorders associated with, for example, insulin such as diabetes. The reduction in NH
06/19/2007
7202277Benzamidine derivatives having anti-inflammatory and immunosuppressive activity
Compounds which can be represented by the general formula (I) indicated below: and in which: A is selected independently from the carboxamide group, the thiocarboxamide group, a...
04/10/2007
7186736NNI for treatment of multi-drug resistant HIV
The present invention is directed to compounds and methods suitable for the treatment of HIV infection. ...
03/06/2007
71698153-methoxybenzyl thiourea derivatives and improved lipid compositions containing same
1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods...
01/30/2007
71055673-substituted urea derivatives and medicinal use thereof
The present invention relates to a urea derivative of the formula (1) wherein each symbol is as described in the specification, a pharmaceutically acceptable salt thereof and pharmaceutical use thereof. The compo...
09/12/2006
7094807Substituted aryl thioureas and related compounds; inhibitors of viral replication
The invention provides compounds and pharmaceutically acceptable salts of Formula I wherein the variables A1, A2, R1, R2, V, W, X, Y, and Z are defined herein. Certain compou...
08/22/2006
70532433-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same
1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods...
05/30/2006
6984647Aminotetralin-derived urea modulators of vanilloid VR1 receptor
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain ...
01/10/2006
6962945N-aryloxypropanolyl-N′-phenethyl-urea
The present invention provides N-aryloxypropanolyl-N′-phenethyl-urea derivatives of formula 3, method for their preparation and use thereof as potent appetite suppressants for treatment of obesity wherein R is select...
11/08/2005
6924311Methods for affecting various diseases utilizing LXR compounds
The present invention relates to methods for elevating high density lipoprotein (HDL) plasma levels, decreasing the absorption of dietary cholesterol in the intestine, decreasing the plasma level of low density lipoprotein (LDL), and increasing the conversion of cho...
08/02/2005
6838472Substituted urea retinoid agonists
The current invention provide novel compounds, methods of treating or preventing emphysema, cancer and dermatological disorders, pharmaceutical compositions suitable for the treatment or prevention of emphysema, cancer and dermatological disorders and methods for de...
01/04/2005
6713650ABCA-1 elevating compounds
The present invention provides compounds that elevate cellular expression of the ABCA-1 gene, promoting cholesterol efflux from cells and increasing HDL levels in the plasma of a mammal, in particular humans. The compounds are useful for treating coronary artery dis...
03/30/2004
6620806Methods and kits for improving vascular health
The present invention provides methods and kits for improving or maintaining vascular health, including preventing myocardial infarction or stroke; maintaining or improving vascular reactivity; treating acute or chronic renal failure, peripheral arterial ...
09/16/2003
6608052Compounds useful as anti-inflammatory agents
Disclosed are novel aromatic compounds of the formula(I) wherein G, E, W, Ar, X, Y and Z. The compounds are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceut...
08/19/2003
6573284Method of treating melanoma
Novel pro-drugs and assay reagents are provided which are useful as therapeutic agents especially for delivery and targetting therapeutically active agents to melanoma cells. The pro-drugs and assay reagents are substrates for tyrosinase and may be repres...
06/03/2003
6545052Methods and compositions for inhibiting free radical polymerization in skin and hair
A method is provided for inhibiting free radical degradation in the skin of a human or nonhuman animal comprising contacting the skin with a skin treatment composition having a concentration of a 1-(3-methoxybenzyl)-3-substituted thiourea compound effecti...
04/08/2003
6479458Targeting the reverse mode of the Na+/Ca2+ exchanger for the treatment of optic neuropathy associated with glaucoma and ischemic optic neuropathy
A method for preventing retinal ganglion cell depth, associated with glaucoma, in an animal of the mammalian species, including humans, comprising the step of administering to ganglion cells and their axons (optic nerve) of said mammal a pharmaceutical co...
11/12/2002
6414030Use of benzenesulfonyl(thio)ureas for the treatment and prophylaxis of dysfunctions of the autonomous nervous system and use of benzenesulfonyl(thio)ureas in combination with beta-receptors blockers
Substituted benzenesulfonylureas and -thioureas of the formula I ##STR1## in which R1, R2, E, X, Y and Z have the meanings described herein, show effects on the autonomous nervous system. The invention relates to the use of the compo...
07/02/2002
6362228Phenethyl-thiourea compounds and use
Novel phenylethyl-thiourea (PHET) compounds as inhibitors of reverse transcriptase and effective agents for the treatment of HIV infection, including mutant, drug-sensitive, drug-resistant, and multi-drug resistant strains of HIV....
03/26/2002
6316478IL-8 receptor antagonists
This invention relates to novel spiro compound derivatives of benzoisothiazolyl-urea and -thiourea and compositions thereof. These compounds are useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8)....
11/13/2001
6316503LXR modulators
The invention provides compounds, compositions and methods for modulating the effects of LXR in a cell. The compounds and compositions are useful both as diagnostic indicators of LXR function and as pharmacologically active agents. The compounds and compo...
11/13/2001
6313172Methods and compositions for modulating alpha adrenergic receptor activity
Methods and compositions for the treatment of pain using this area derivatives. Particularly disclosed are new compositions for the treatment of chronic pain, and methods for their use....
11/06/2001
6271261IL-8 receptor antagonists
Novel IL-8 receptor antagonists and methods of using them are provided....
08/07/2001
6255349Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
Compounds having the formula: ##STR1## wherein R1 -R5 are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycl...
07/03/2001
6207715Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
Compounds of the formula: ##STR1## are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi he...
03/27/2001
6187799Inhibition of raf kinase activity using aryl ureas
Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se....
02/13/2001
6093742Inhibitors of p38
The present invention relates to inhibitors of p38, a mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provi...
07/25/2000
6034102Atherosclerosis treatment
A method of treating atherosclerosis, independent of lipid lowering, in mammals, including humans, in need of treatment by inhibiting progression of an atherogenic lesion or by stabilizing plaque. Such lesion progression inhibition or plaque stabilization...
03/07/2000
5977177Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them
This invention relates to substituted benzenesulfonylureas and -thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them. Substituted benzenesulfonylureas and -thioureas of the ...
11/02/1999
5958983Polyaromatic antiviral compositions
The present invention relates to polyaromatic compounds having useful antiviral activity against viruses of the herpes family, to a composition containing them, and to a method of using them for the treatment of herpes viruses infections....
09/28/1999
5952386Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production
The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen...
09/14/1999
5929117Immunotherapeutic agents
Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor ଱, nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory con...
07/27/1999
5928633Material for elimination or detoxification of super antigens
A material with excellent selective absorption of super antigens. Said material contains urea bonds or thiourea bonds and remains active even in a high protein concentration solution in the neutral region, Activity remains after sterilization. Also provid...
07/27/1999
5886044IL-8 receptor antagonists
This invention relates to the novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8)....
03/23/1999
5880155Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them
This invention relates to substituted benzenesulfonylureas and -thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them. Substituted benzenesulfonylureas and -thioureas of the ...
03/09/1999
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