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| Number | Title | Issue Date |
| 5985296 | Complexes of gamma-cyclodextrin and retinol or retinol derivatives, processes for their preparation and their use Complexes of γ-cyclodextrin and retinol or retinol derivatives, along with processes for their preparation and compositions for their use. The complexes are useful in cosmetic formulations and in pharmaceutical formulations.... | 11/16/1999 |
| 5985310 | Preservative systems for pharmaceutical compositions containing cyclodextrins Disclosed are preservative systems useful in aqueous pharmaceutical compositions containing an active agent and a cyclodextrin. The preservative systems comprise boric acid and one or more compounds selected from the group consisting of C16 ben... | 11/16/1999 |
| 5972910 | Delivery system for antimethanogenic agents A delivery system is provided to reduce methane production in animals or to improve the weight gain of an animal. Embodiments include a delivery system comprising a volatile and/or water soluble antimethanogenic agent with cyclodextrin or a cyclodextrin-l... | 10/26/1999 |
| 5942217 | Uncomplexed cyclodextrin compositions for odor control The present invention relates to a stable, aqueous odor-absorbing composition, preferably for use on inanimate surfaces. The composition comprises from about 0.1% to about 20%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclo... | 08/24/1999 |
| 5942501 | Cyclodextrin derivative complex A salicylic acid (SA) and derivitized beta cyclodextrin complex provides that the SA display increased solubility in water. The complex includes about 0.1 to about 10.0 percent salicylic acid, about 0.1 to about 75.0 percent derivatized beta cyclodextrin ... | 08/24/1999 |
| 5935940 | Compositions and methods for modulating growth of a tissue in a mammal Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low sol... | 08/10/1999 |
| 5935941 | Alkylations of cyclodextrins leading to derivatives which have a ridgidly extended cavity By controlling basicity of the reaction, is possible to alkylate preferentially the secondary hydroxyls of cyclodextrins. These hydroxyls surround the principal, wide, entry into the cyclodextrin cavity and, thus, their substitution by suitably chosen sub... | 08/10/1999 |
| 5929052 | Energy formulation A novel dextrin-type starch is suitable for supplying energy to human beings in preparation for or after a physical activity. The starch is characterized in that it has a molecular weight of from about 15,000 to about 10,000,000, and in that its molecules... | 07/27/1999 |
| 5916883 | Acylated cyclodextrin derivatives A cyclodextrin derivative, wherein at least 60 percent of the free hydroxy groups of said cyclodextrin are acylated with acyl groups where at least one of said acyl groups comprise a free carboxylic group.... | 06/29/1999 |
| 5906981 | Halopropargyl inclusion complexes A biocidal composition which comprises an inclusion complex of a halopropargyl compound and a cyclodextrin or a modified cyclodextrin, useful broadly in industrial systems and more particularly in aqueous compositions used in connection with paints, coati... | 05/25/1999 |
| 5904929 | Acylated cyclodextrin-containing pharmaceutical composition A pharmaceutical composition for trans-mucosal or transdermal administration wherein a per-C2-18 acylated cyclodextrin is used as a drug reservoir or carrier. The composition can be used safely and exhibits excellent drug release behavior.... | 05/18/1999 |
| 5902799 | Methods of modulating tissue growth and regeneration Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low sol... | 05/11/1999 |
| 5902797 | Nutritional supplement for use in the treatment of attention deficit A nutritional supplement comprising approximately from about 5 to about 25 grams carbohydrate; approximately from about 1 to about 25 grams protein; and approximately from about 1 to about 10 grams fat, for use in treating low appetite that may result in ... | 05/11/1999 |
| 5888987 | Solvent dried polysaccharide sponges The invention provides a method of preparing water-insoluble polysaccharide sponges, and sponges obtained by means of the method. The method comprises: (a) providing an aqueous solution of a soluble polysaccharide; (b) freezing the solution; (c) treating ... | 03/30/1999 |
| 5874419 | Compositions and methods for modulating growth of a tissue in a mammal Polyionic derivatives of cyclodextrins and methods for preparing these derivatives are provided in which a polyionic derivative of cyclodextrin is combined with a growth factor, preferably a heparin binding growth factor. These compositions are of low sol... | 02/23/1999 |
| 5874418 | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use Sulfoalkyl ether-cyclodextrin (SAE-CD) based pharmaceutical formulations are provided by the present invention. These formulations comprise SAE-CD derivatives and a therapeutic agent, a major portion of which is not complexed to the SAE-CD. The present fo... | 02/23/1999 |
| 5866533 | Polyhydroxycarboxylic acid composition derived from maltodextrins by oxidation with an oxygen containing oxidant The present invention a polyhydroxycarboxylic acid composition derived from maltodextrins by oxidation with an oxygen containing oxidant. The invention also relates to a process for the production of oxyacids from carbohydrates by oxidation with an oxygen... | 02/02/1999 |
| 5861383 | Sulfated polysaccharide fractions having anti-HIV activity Various peptides having affinity for sulfated polysaccharides such as heparin, dextran sulfate and Pentosan polysulfate are bound to resins and used in affinity chromatography to prepare anti-HIV sulfated polysaccharides.... | 01/19/1999 |
| 5856359 | Thyroxine/cyclodextrin complexes and pharmaceutical compositions containing the same Thyroxine containing pharmaceutical compositions with improved aqueous solubility, stability and enhanced membrane permeation have been prepared by formulating thyroxine with cyclodextrins. These thyroxine/cyclodextrin complexes can further be transformed... | 01/05/1999 |
| 5854225 | Compounds derived from cyclodextrin The invention relates to cyclodextrin derivatives of formula (I) CD(OH)I (OCOR)m (OR2)n (1) in which each R1 independently denotes a C6 -C24 alkyl radical or a C8 | 12/29/1998 |
| 5854226 | Pharmaceutical composition A pharmaceutical composition for oral administration for the treatment of acute pain and inflammation comprises an inclusion complex of a non-steroidal anti-inflammatory drug or a pharmaceutically acceptable salt thereof and a cyclodextrin, and a physiolo... | 12/29/1998 |
| 5846954 | Cyclodextrin compounds and methods of making and use thereof The present invention provides polyanionic, substituted CDs having cellular growth modulating-activity. The invention further provides CDs having anionic groups on one side of the CD molecule. Therapeutic methods for using, as well as methods of making th... | 12/08/1998 |
| 5843920 | Anionic saccharides for extraction of anti-angiogenic protein from cartilage Anti-angiogenic protein composition can be prepared simply and efficiently by contacting cartilage particles containing the protein together with an electrolyte solution and an oligosaccharide bearing a minimum number of anionic substituents per sugar uni... | 12/01/1998 |
| 5840714 | Inclusion complexes of racemic ibuproxam and of optically active ibuproxam with cyclodextrin derivatives, pharmaceutical preparations containing said inclusion complexes and methods for using same Inclusion Complexes of Racemic Ibuproxam and of Optically Active Ibuproxam with Cyclodextrin Derivatives, Process for the Preparation Thereof, Pharmaceutical Preparations Containing these Inclusion Complexes or Containing Optically Active S-(+)-Ibuproxam,... | 11/24/1998 |
| 5840713 | Therapy for tissue membrane insufficiency Disclosed are methods of therapy applicable to pathologies that involve loss of integrity of tissue and organ membranes that lead to abnormal permeation of proteinic and other agents and their elimination or penetration of other anatomical functions. Such... | 11/24/1998 |
| 5834446 | Nerve process growth modulators Nerve process growth modulation can be achieved using derivatized cyclodextrins. Processes for making sulfated and aminated ଲ-cyclodextrin derivatives are also described in which a compound of the formula R"2 NCH X'+ X'- | 11/10/1998 |
| 5834445 | Process for preparing decolorized carotenoid-cyclodextrin complexes Complexes of ଲ carotene with cyclodextrin are described, having reduced color intensity and a shift of color to tones more neutral than the deep red of uncomplexed ଲ carotene. When these complexes are added to topical compositions such as typi... | 11/10/1998 |
| 5814638 | Ophthalmic formulation for treating myopia comprising dopamine agonist and cyclodextrin An ophthalmic formulation for treating myopia, which comprises a dopamine agonist and cyclodextrin or its derivative in combination with a pharmaceutically acceptable carrier.... | 09/29/1998 |
| 5807844 | Production of toxin binding biopolymers, use thereof A method for production of toxin-binding, non-toxic, modified, biopolymers and the use thereof for the treatment of septic shock, infections and toxic states and to the use of them as carriers for transportation of biologically or therapeutically importan... | 09/15/1998 |
| 5804568 | Pharmaceutical formulation Compositions of matter comprising a substituted cyclodextrin and cytotoxic compound, especially cytotoxic drugs such as antibiotic, anti-fungal and anti-neoplastic, drugs are claimed. The compositions cause significantly less ulceration compared to the sa... | 09/08/1998 |
| 5798342 | Use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of ginkgolides The invention relates to the use of natural cyclodextrins and their derivatives for the solubilization of platelet anti-aggregating agents from the family of Ginkgolides. The cyclodextrins used comply with the formula: ##STR1## in which n is equal to... | 08/25/1998 |
| 5798338 | Solid dosage forms that contain clathrates of 17-ethinyl estradiol A method and pharmaceutical compositions are disclosed for reducing oxidative degradation of 17 -ethinylestradiol comprising combining the estradiol with an effective amount of cyclodextrin, thus forming a cyclodextrin clathrate of the steroid.... | 08/25/1998 |
| 5780452 | Antimalarial drug A novel antimalarial drug having high therapeutic effect, which comprises a sulfated polysaccharide or a pharmaceutically acceptable salt thereof as an active ingredient or both of a sulfated polysaccharide or a pharmaceutically acceptable salt thereof an... | 07/14/1998 |
| 5776914 | Prevention of hemolysis Disclosed are compositions and methods for preventing or substantially inhibiting the hemolytic activity of hemolysis inducing agents. The methods and compositions are based on the use of an anionic oligosaccharide, such as polysulfated cyclodextrin, to a... | 07/07/1998 |
| 5773427 | Prevention of fiber-induced intestinal gas production by chitosan The tendency of an orally-ingestible dietary fiber composition to cause excessive flatulence upon oral administration is reduced considerably by the incorporation therein, in addition to other dietary fiber components, a flatulence-reducing amount of chit... | 06/30/1998 |
| 5770596 | Pharmaceutical compositions based on mequitazine The subject of this invention is a ready-for-use collyrium intended for the treatment of ocular allergies, comprising, in aqueous solution, mequitazine and a ଲ- or a γ-cyclodextrin optionally etherified by C1 -C4 alkyl or C | 06/23/1998 |
| 5767109 | Complexing urushiols This invention relates to use of cyclodextrins to complex urushiols to protect against and to treat irritation arising from exposure to urushiols. cyclodextrins, particularly gamma-cyclodextrins, are capable of binding strongly to urushiols and can be use... | 06/16/1998 |
| 5760014 | Therapeutic carbohydrate blends useful for aiding premenstrual syndrome A method of managing or alleviating carbohydrate craving, binge eating, anxiety, or depression entails administering an aqueous carbohydrate blend containing dextrose, dextrin, maltodextrin or a mixture thereof, and starch, pregelatinized starch, or a mix... | 06/02/1998 |
| 5760017 | Cyclodextrin derivatives usable in particular for solubilizing hydrophobic chemical compounds such as medicaments and their preparation process The invention relates to novel cyclodextrin derivatives according to formula: ##STR1## in which R1 represents OH or NH(CH2)p OH, n is equal to 5, 6 or 7 and p is an integer from 2 to 6, it being possible for the p to ... | 06/02/1998 |
| 5760016 | Use of mono-3,6-anhydrocyclodextrins for solubilizing a hydrophobic compound and for controlling the purity of an enantiomer and process for the preparation of these cyclodextrins The invention relates to the use of mono-3,6-anhydrocyclodextrins for solubilizing a hydrophobic compound and for controlling the purity of an enantiomer. The mono-3,6-anhydrocyclodextrin complies with the following formula: ##STR1## in which n is eq... | 06/02/1998 |
