Bizarre Patents
A Christmas stocking having illumination means associated therewith for signalling the arrival of Santa Claus.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8173706 | L-ornithine phenyl acetate and methods of making thereof Disclosed herein are crystalline forms of L-ornithine phenyl acetate and methods of making the same. The crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liv... | 05/08/2012 |
| 7897644 | Use of 4-oxobutanoic acid derivatives in the treatment of inflammation The present invention relates to the use of a 4-oxobutanoic acid derivative for the preparation of a pharmaceutical composition for treating inflammation. ... | 03/01/2011 |
| 7858664 | Histone deacetylase inhibitors Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, such as, for example, a hydroxamic acid group or a carboxylic acid group, can inhibit histone deacetylase. Histone deacetylase can repress gene expression, ... | 12/28/2010 |
| 7358262 | Identification of genotype-selective anti-tumor agents The present invention relate to methods of identifying a genotype-selective agent. In certain embodiments, the invention relates to agents that are selectively toxic to engineered human tumorigenic cells. ... | 04/15/2008 |
| 7329782 | Compounds for the treatment of metabolic disorders Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed. ... | 02/12/2008 |
| 7319096 | Thyroid hormone receptor antagonists for cardiac and metabolic disorders II This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism... | 01/15/2008 |
| 7291599 | Use of inhibitors of enzymes having activities of amino peptidase N and/or dipeptidyl peptidase IV and of pharmaceutical preparations thereof for a therapy and prevention of chronical neurodegenerative diseases The invention relates to a process for the treatment of neurodegenerative diseases wherein mis-folded proteins accumulate in characteristic lesions and contribute substantially to a pathogenesis and to an inflammatory reaction magnifying the damage, by the isolated ... | 11/06/2007 |
| 7285572 | CaSR antagonist The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist and a therapeutic drug for osteoporosis. A compound represented by the... | 10/23/2007 |
| 7244759 | Isoindoline compounds and methods of making and using the same The invention encompasses isoindoline compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment, prevention or management of various diseases and disorders. Examples include, but are not limited to, cancer, inflammatory bowel... | 07/17/2007 |
| 7229969 | Combinations of enzyme inhibitors and the use thereof Combination of inhibitors of dipeptidyl peptidase IV (DP IV) and enzymes having the same substrate specificity (DP IV-analogous enzymatic activity) and inhibitors of alanyl aminopeptidase (aminopeptidase N, APN) and of enzymes having the same substrate specificity (... | 06/12/2007 |
| 7208601 | Aryl and heteroaryl compounds, compositions, and methods of use This invention provides aryl and heteroaryl compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention may be useful as antagonists, or partial an... | 04/24/2007 |
| 7141238 | Compositions for reducing UV-induced inhibition of collagen biosynthesis in human skin Exposure of human skin to ultraviolet (UV) radiation from the sun not only induces the production of enzymes (matrix metalloproteinases) that degrade collagen, but also inhibits the synthesis of new collagen by inhibiting the synthesis of procollagen. This UV-induce... | 11/28/2006 |
| 7122580 | Aryl and heteroaryl compounds and methods to modulate coagulation This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention are useful as antagonists, or more preferably, partial ... | 10/17/2006 |
| 7115640 | Heterocyclic modulators of nuclear receptors Compounds, compositions and methods for modulating the activity of nuclear receptors are provided. In particular, heterocyclic compounds are provided for modulating the activity of farnesoid X receptor (FXR), liver X receptor (LXR) and/or orphan nuclear receptors. I... | 10/03/2006 |
| 7109164 | Aniline-derived ligands for the thyroid receptor New thyroid receptor ligands are provided which have the general formula in which: X is —O—, —S—, —CH2—, —CO—, or —NH—; Y is —(... | 09/19/2006 |
| 7074770 | Method of DNA vaccination A method of vaccinating a mammal against a disease state, comprising administrating to said mammal, within an appropriate vector, a nucleotide sequence encoding an antigenic peptide associated with the disease state; additionally administering to said mammal a compo... | 07/11/2006 |
| 7037914 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I) (wherein all symbols are as defined in the specification), a non-toxic acid thereof or a hydrate thereof as ... | 05/02/2006 |
| 7019031 | Anticancer agents based on regulation of protein prenylation Oncoproteins such as Ras and RhoB are known to induce cell division in an unrestrained manner when such proteins are localized at the inner surface of a cancer cell membrane. The localization is effected by the prenylation reaction, whereby a hydrophobic group (e.g.... | 03/28/2006 |
| 7014864 | Formulations comprising lipid-regulating agents The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one structured lipid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation. ... | 03/21/2006 |
| 6984389 | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M ... | 01/10/2006 |
| 6982097 | Biocidal compositions and methods of using same This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using the biocidal compositions for the disinfection of water that may conta... | 01/03/2006 |
| 6974595 | Pharmaceutical compositions based on Diclofenae New pharmaceutical compositions for oral use containing Diclofenac together with alkali metal bicarbonates in amounts of from 20 to 80 by weight with respect to Diclofenac are described. These compositions are entirely palatable and free from any unpleasant taste or... | 12/13/2005 |
| 6962714 | Critical fluid antimicrobial compositions and their use and generation The present invention relates to antimicrobial compositions including a critical, near critical, or supercritical (densified) fluid and an antimicrobial agent, to methods of forming these compositions, and to methods employing these compositions. An antimicrobial ag... | 11/08/2005 |
| 6960344 | Use of imine-forming polysaccharides as adjuvants and immunostimulants The present invention relates to polysaccharide conjugates that comprise: a polysaccharide that binds to surface-receptors present on Antigen Presenting Cells, conjugated to one or more compounds having stable carbonyl groups covalently attached, either directly or ... | 11/01/2005 |
| 6953786 | Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof Disclosed are methods for treating, preventing, or inhibiting cancer in a subject comprising administering at least one polyphenolic compound and at least one inhibitor of reactive oxygen species to the subject. The polyphenolic compound may be derived or isolated f... | 10/11/2005 |
| 6943194 | Synthesis of phenstatin and prodrugs thereof A newly discovered antineoplastic compound denominated “phenstatin” is herein described as are synthetic methods for producing phenstatin and the active prodrug thereof. Phenstatin was converted to the sodium phosphate prodrug (3d) by a dibenzylphosphite phospho... | 09/13/2005 |
| 6939896 | Cd45 inhibitors Substituted naphthalenediones in accord with structural diagram (I): compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In compounds of the invention, wherein: ... | 09/06/2005 |
| 6919072 | Methods and compositions for reducing collagen loss due to chronological aging in human skin Chronological aging of human skin can be delayed with the topical application of an MMP inhibitor, preferably a retinoid (an indirect MMP inhbitor); retinoids also normalize procollagen biosynthesis. Chronological aging, or natural aging, is evidenced in elderly (80... | 07/19/2005 |
| 6911473 | Detectable agent for wood treatment and method for its detection The present invention relates to a composition comprising an organic preservative acid and a UV-active indicator substance for preserving wood and for detection of the sufficient preservation of wood. ... | 06/28/2005 |
| 6852878 | Thioketals and thioethers for inhibiting the expression of VCAM-1 Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders,... | 02/08/2005 |
| 6835749 | Sulfohydroxamic acids and sulfohydroxamates and their use as MEK inhibitors Sulfohydroxamic acid diarylamines and derivatives thereof; compositions made from them; and methods of using them. ... | 12/28/2004 |
| 6814977 | Formulations comprising lipid-regulating agents The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one medium chain glycerol ester of a fatty acid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation. ... | 11/09/2004 |
| 6803057 | Hydrogen peroxide disinfectant with increased activity An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations contain about 0.5% wt./wt. % H2O2. The solution also contains from 0.05 to... | 10/12/2004 |
| 6800605 | Aniline-derived ligands for the thyroid receptor New thyroid receptor ligands are provided which have the general formula in which: X is —O—, —S—, —CH2—, —CO—, or —NH—; Y is —(CH2)n— where n is an i... | 10/05/2004 |
| 6797728 | Use of intracellular calcium chelators to increase surfactant secretion in the lungs Pulmonary surfactant is required in order to reduce surface tension in the lungs so that less effort is needed to reinflate the lungs after exhalation. A number of diseases and conditions exist that disrupt the normal flow of surfactant secretion, resulting in respi... | 09/28/2004 |
| 6787528 | Inhibitors of intestinal apical membrane Na/phosphate co-transportation The compounds of formula (I) are hydrophilic aryl phosphate, thiophosphate, and aminophosphate intestinal apical membrane Na-mediated phosphate co-transportation inhibitors. The compounds can be administered orally, where they act to inhibit Na-dependent phosphate u... | 09/07/2004 |
| 6787573 | Antiviral therapy The invention relates to the field of antiviral agents, and more specifically to antiviral therapy. The invention provides use of at least one compound or mixture of compounds of the general formula or a functional equiv... | 09/07/2004 |
| 6749869 | Acidic aqueous chlorite teat dip providing shelf life, sanitizing capacity and tissue protection The mastitis control teat dip composition of the invention provides rapid initial kill, a useful highly pseudoplastic rheology, a barrier/film-forming capacity, a unique antimicrobial composition that is stable over an extended period of time, and unexpected long te... | 06/15/2004 |
| 6723750 | Photodynamic therapy for pre-melanomas Method for treating dermal pre-melanoma conditions which include administering an effective amount of a photosensitive agent to a dermal pre-melanoma cell and activating the photosensitive agent, thereby treating a dermal pre-melanoma condition. ... | 04/20/2004 |
| 6706290 | Methods for eradication of nanobacteria Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The present invention provides methods for sterilizing articles contaminated ... | 03/16/2004 |
