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"To place a man in a multi-stage rocket and project him into the controlling gravitational field of the moon where the passengers can make scientific observations, perhaps land alive, and then return to earth--all that constitutes a wild dream worthy of Jules Verne. I am bold enough to say that such a man-made voyage will never occur regardless of all future advances."
Lee deForest, American radio pioneer ; 1957
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| Number | Title | Issue Date |
| 8183291 | Clear ophthalmic solution comprising latanoprost as active ingredient A clear ophthalmic solution containing latanoprost having a concentration of 0.005% (W/V), 0.003 to 0.01% (W/V) benzalkonium chloride and at least one agent selected from the group consisting of glycerin, polyethylene glycol, propylene glycol and trehalose, wherein ... | 05/22/2012 |
| 8168680 | Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising | 05/01/2012 |
| 8143312 | Transparent eye drops containing latanoprost An object of the present invention is to provide better formulations of a latanoprost ophthalmic solution. The present invention provides a clear ophthalmic solution comprising latanoprost as an active ingredient and benzalkonium chloride as a preservative wherein w... | 03/27/2012 |
| 8114911 | Prostaglandin compounds for the treatment of obesity Provided is a composition for treating obesity which comprises an effective amount of a prostaglandin compound, especially, a compound of formula (I). ... | 02/14/2012 |
| 8106096 | Compositions and methods for treatment of optic nerve diseases The present invention provides a method for treating or reducing damage to the optic nerve in a subject comprising administering to the subject a therapeutically effective amount of prostaglandin J2 alone or in combination with an effective amount of GM-CSF. In part... | 01/31/2012 |
| 8097653 | Dosage unit comprising a prostaglandin analog for treating constipation A dosage unit for treating constipation in a human patient is described. The dosage unit of the invention comprises a halogenated prostaglandin analog and a pharmaceutically suitable excipient. The dosage unit relieves constipation without substantial side effects. | 01/17/2012 |
| 8084501 | Stable prostaglandin-containing compositions A pharmaceutical composition containing a prostaglandin and an alkanoic acid ester of a polyethoxylated sorbitol in an amount effective to enhance the chemical stability of the prostaglandin, and the use thereof for treating ophthalmic conditions. Also disclosed are... | 12/27/2011 |
| 7893107 | Therapeutic methods using prostaglandin EPagonist components Methods are provided directed to administering a therapeutically effective amount of a prostaglandin EP4 agonist component to a mammal afflicted with or prone to afflicted with a disease or condition selected from an esophageal ulcer, alcohol gastropathy,... | 02/22/2011 |
| 7888392 | Ointment An ointment containing a compound represented by formula (I): [wherein R1 represents any group of a group represented by the formula: —(CH2)4â€... | 02/15/2011 |
| 7879910 | Compositions and methods for promoting lush hair growth Compositions, kits and methods are provided for conditioning, revitalizing, volumizing or increasing the natural pigmentation of the hair, including hair on the scalp, eyelashes, eyebrows, mustache and beard, promoting healthy growth, and treating and preventing los... | 02/01/2011 |
| 7879909 | Use of Treprostinil to treat neuropathic diabetic foot ulcers The present invention describes novel methods for using 9-deoxy-2′,9-α-methano-3-oxa-4,5,6-trinor-3,7-(1′,3′-interphenylene)-13,14-dihydro-prostaglandin F1 (also known as Treprostinil) or its derivative, or a pharmaceutically acceptable salt thereo... | 02/01/2011 |
| 7868045 | Method for promoting gastrointestinal bicarbonate secretion Provided is a method for promoting bicarbonate secretion in the stomach or duodenum in a mammalian subject, which comprises administering an effective amount of a compound of Formula (I): to a subject in need thereof, where... | 01/11/2011 |
| 7795312 | Method for treating abdominal discomfort A method for treating irritable bowel syndrome in a mammalian subject includes administering an effective amount of 13,14-dihydro-15-keto-16,16-difluoro-18-methyl-prostaglandin E1 or 13,14-dihydro-15-keto-16,16-difluoro-prostaglandin E1, or a s... | 09/14/2010 |
| 7718701 | Antipruritic agent A method of treating atopy-evoked pruritic symptoms by administering a prostaglandin derivative. ... | 05/18/2010 |
| 7671091 | Penis enlargement A method for causing a permanent increase in the length and girth of a male subject's penis, the method comprising treatment comprising the step of (a) administering to the male an effective amount of a vasodilator selected from the group consisting of a vasodilator... | 03/02/2010 |
| 7608642 | Wound and skin care compositions The invention provides compositions and methods that employ compounds that can promote skin cell renewal, wound healing, proliferation of fibroblasts and/or keratinocytes, and production of collagen or fibronectin by fibroblasts. These compositions and methods are u... | 10/27/2009 |
| 7560489 | Stabilized prostaglandin E composition A prostaglandin E composition comprises are substantially free from C1-C4 alcohols and include the prostaglandin E compound together with a (C1-C4)-alkyl(C8-C22)carboxylic ester (e.g., ethyl laurate),... | 07/14/2009 |
| 7553875 | Prostaglandin analog compositions and methods to treat epithelial-related conditions The present invention relates to the formulation and delivery of prostaglandin analogs to treat epithelial-related condition. In some embodiments, the compositions of the invention are used to stimulate hair growth. In some embodiments, the compositions of the inven... | 06/30/2009 |
| 7553874 | Prostaglandin analog compositions and methods to treat epithelial-related conditions The present invention relates to the formulation and delivery of prostaglandin analogs to treat epithelial-related condition. In some embodiments, the compositions of the invention are used to stimulate hair growth. In some embodiments, the compositions of the inven... | 06/30/2009 |
| 7550508 | Prostaglandin analog compositions and methods to treat epithelial-related conditions The present invention relates to the formulation and delivery of prostaglandin analogs to treat epithelial-related condition. In some embodiments, the compositions of the invention are used to stimulate hair growth. In some embodiments, the compositions of the inven... | 06/23/2009 |
| 7541382 | Prostaglandin analog compositions and methods to treat epithelial-related conditions The present invention relates to the formulation and delivery of prostaglandin analogs to treat epithelial-related condition. In some embodiments, the compositions of the invention are used to stimulate hair growth. In some embodiments, the compositions of the inven... | 06/02/2009 |
| 7517912 | Prostaglandin analog compositions and methods to treat epithelial-related conditions The present invention relates to the formulation and delivery of prostaglandin analogs to treat epithelial-related condition. In some embodiments, the compositions of the invention are used to stimulate hair growth. In some embodiments, the compositions of the inven... | 04/14/2009 |
| 7514474 | Prostaglandin analog compositions and methods to treat epithelial-related conditions The present invention relates to the formulation and delivery of prostaglandin analogs to treat epithelial-related condition. In some embodiments, the compositions of the invention are used to stimulate hair growth. In some embodiments, the compositions of the inven... | 04/07/2009 |
| 7498360 | Method and compositions for local treatment of Meniere's disease, tinnitus and/or hearing loss A novel method and compositions for the local treatment of Meniere's disease, tinnitus and hearing loss are described. The treatment is based on the administration of a therapeutically effective amount of a prostaglandin of the F-type to the inner ear. The treatment... | 03/03/2009 |
| 7425651 | Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof The present invention provides novel jasmonate derivative compounds, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially as chemotherapeutic agents for treatment of ca... | 09/16/2008 |
| 7405240 | Substituted cyclopentanes or cyclopentanones as therapeutic agents The compounds disclosed herein are useful for treating glaucoma, ocular hypertension, and baldness. ... | 07/29/2008 |
| 7405222 | Methods and compositions for treatment of erectile dysfunction Disclosed are methods and compositions for treatment of male sexual dysfunction. A method of treating male sexual dysfunction includes administering a pharmaceutical composition effective to cause said male to sustain an erection. The composition is formulated based... | 07/29/2008 |
| 7381748 | Compounds and related methods for inhibition of gamma-aminobutyric acid aminotransferase (1S, 3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic acid illustrates a novel class of compounds as potent irreversible inhibitors of γ-aminobutyric acid aminotransferase (GABA-AT). The corresponding monofluoro-substituted compounds also are potent time-dependent ... | 06/03/2008 |
| 7358226 | Ultrasonic concentration of drug delivery capsules Methods, compositions and apparatus for localized delivery of compounds are provided. In certain embodiments, radiation force is used to direct carriers to a target site, and additional radiation is used to fragment the localized carriers, releasing associate compou... | 04/15/2008 |
| 7355064 | Method for preparing 15-keto-prostaglandin E derivative Disclosed is an improved method for preparing 15-keto-prostaglandin E derivative. According to the invention, the deprotection of protected hydroxy group required in manufacturing a 15-keto-prostaglandin derivative is conducted under the presence of a phosphoric aci... | 04/08/2008 |
| 7341737 | Medicated tampon A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body having a distal end; and a dosage form affixed to the distal end of the tampon body, wherein the dosage form includes a formulation including a therapeutic agent, and wherein the dos... | 03/11/2008 |
| 7320967 | Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair The invention relates to a cosmetic composition containing at least one 15-hydroxy-prostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of cosmetic treatment for promoting the growth and/or preventing or delaying ... | 01/22/2008 |
| 7318930 | Control methods for boring bark beetles A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which... | 01/15/2008 |
| 7303768 | Preparation of aqueous clear solution dosage forms with bile acids Compositions for pharmaceutical and other uses comprising clear aqueous solutions of bile acids which do not form any detectable precipitates over selected ranges of pH values of the aqueous solution and methods of making such solutions. The compositions of the inve... | 12/04/2007 |
| 7276050 | Trans-scleral drug delivery method and apparatus A method of treating ocular disorders involving angiogenesis includes the steps of providing a trans-scleral drug delivery device comprising an insert stabilizer for attachment to a scleral surface and having an interlock opening and a replaceable implant having a r... | 10/02/2007 |
| 7268141 | Xanthine phosphodiesterase V inhibitors A xanthine phosphodiesterase V inhibitor having the formula (I), with the variables defined herein, which is especially useful for treating male (erectile) and female sexual dysfunction and other physiological disorders: | 09/11/2007 |
| 7268163 | Method for treating an inflammation or lesion caused by a virus A method for treating an inflammation or lesion caused by herpesvirus, comprising topically applying to said inflammation or lesion a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust... | 09/11/2007 |
| 7267670 | Reinforced urethral suppository A urethral suppository comprising a non-meltable base member sized to prevent insertion of the base member into the urethra, a non-meltable reinforcement projecting from the base member, and a meltable portion formed around a portion of the reinforcement. The meltab... | 09/11/2007 |
| 7258850 | Methods and compositions for treating erectile dysfunction Methods are provided for increasing libido and/or treating erectile dysfunction in a man. The methods include the administration of a formulation testosterone alone, another fast-acting drug to treat erectile dysfunction or a combination of the testosterone and the ... | 08/21/2007 |
| 7255984 | Combination therapy for osteoporosis Pharmaceutical combination compositions including certain estrogen agonists/antagonists and prostaglandins or prostaglandin agonists/antagonists. The compositions are useful for the treatment of bone disorders including osteoporosis. ... | 08/14/2007 |
