...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 8129359 | Composition and method for treating post-surgical pain A composition for reducing pain at a surgical wound site or trauma site comprising oxidized regenerated cellulose and a non-steroidal anti-inflammatory drug or pharmaceutically acceptable salt or ester thereof, where the non-steroidal anti-inflammatory drug is an ac... | 03/06/2012 |
| 8071571 | Orlistat compositions A pharmaceutical combination or composition containing a lipase inhibitor, preferably orlistat, and a bile acid sequestrant is useful for treating obesity. ... | 12/06/2011 |
| 8026226 | Medical and nutritional applications of highly refined cellulose The present invention provides a method for using processed cellulose. Preferably, the processed cellulose is a highly refined cellulose (HRC). The HRC is useful in a number of medical and nutritional applications. These medical and nutritional applications can incl... | 09/27/2011 |
| 7902173 | Compound selected from sulfated cellulose and salts thereof and dermatitis therapeutic agent The present invention provides a compound selected from sulfated cellulose and salts thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, soften, improve or cure atopic cutaneous symptoms and the like ... | 03/08/2011 |
| 7772213 | Composition for the treatment of inflammatory conditions A novel treatment for topical inflammatory conditions such as acne, eczema, shingles, insect bites and hives is provided, consisting of the application of a pharmaceutical cream or ointment which incorporates hydroxypropyl methylcellulose acetate succinate (“HPMCA... | 08/10/2010 |
| 7767656 | Blends of temperature sensitive and anionic polymers for drug delivery A physical blend of inverse thermal gelling and shear-thinning, thixotropic polymers that has a lower gelation temperature than the thermal gelling polymer alone is provided. The blend results in an injectable hydrogel that does not flow freely at room temperature, ... | 08/03/2010 |
| 7612048 | Quick water-dissolving film containing cosmetic, aromatic, pharmaceutical or food substances Film with high solubility in water, comprising a starch, a cellulose and a cosmetic, aromatic, pharmaceutical and/or food substance in a quantity exceeding 10% on the total film weight. ... | 11/03/2009 |
| 7569556 | Method of use of carboxylated polysaccharides topically on the eyeball The use of chemically modified dicarboxy polysaccharides for the topical treatment of the eyeball are described. The modified polysaccharides provide a carrier in solutions for the treatment of the eyeball to obtain a timed release. ... | 08/04/2009 |
| 7427412 | Gel-based cosmetic composition The invention relates to cosmetic compositions comprising an elastic, non-rigid, porous support in which a low-viscosity, gellant-containing, single phase otherwise unstable cosmetic formulation has been incorporated, and a method of making same. ... | 09/23/2008 |
| 7427607 | Drug administration method A method of administering a drug whereby a fine drug powder can be accurately administered to a target site (in particular, a target site in the body cavity) via fluidization and spraying with a gas by using a micro tube. Concerning the administration mode, in parti... | 09/23/2008 |
| 7414039 | Interstitial therapy for immediate symptom relief and chronic therapy in interstitial cystitis The present invention relates to a disorder of the lower urinary tract, and in particular, reducing the symptoms (including treatment) of interstitial cystitis in vivo. In a preferred embodiment, the present invention relates to treatment formulations and methods fo... | 08/19/2008 |
| 7390499 | Microbial cellulose wound dressing for treating chronic wounds The invention relates to a wound dressing comprising a microbial-derived cellulose for treatment of specific types of chronic wounds, including pressure sores, venous and diabetic ulcers. The wound dressing is capable of donating liquid to dry substrates is also cap... | 06/24/2008 |
| 7341741 | Pharmaceutical composition for the treatment of inflammatory bowel disease A polysaccharide selected from xanthan gum and HPMC is used for the treatment or prophylaxis of IBD, especially Crohn's Disease, left-sided ulcerative colitis or pouchitis. ... | 03/11/2008 |
| 7322369 | Methods of detaching microorganisms from, or of inhibiting microbial attachment to, animal or poultry carcasses or seafood or parts thereof Methods of detaching microorganisms (e.g., bacteria) from, or of inhibiting microbial (e.g., bacterial) attachment to, animal or poultry carcasses or seafood or parts thereof, wherein the method involves contacting animal or poultry carcasses or seafood or parts the... | 01/29/2008 |
| 7300670 | Oral suspension formulation An aqueous pharmaceutical suspension for oral administration of a drug, which suspension maintains its content uniformity for prolonged period. ... | 11/27/2007 |
| 7271158 | Treatment of rumen acidosis with α-amylase inhibitors The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of acidosis; a method of treatment of rumen acidosis which comprises administration of ... | 09/18/2007 |
| 7265097 | Methods of drug delivery using sulphated chitinous polymers The present invention provides methods and compositions for delivering a therapeutic agent across a membrane that has limited permeability for the therapeutic agent. The method includes delivering the therapeutic agent to the membrane in a composition which includes... | 09/04/2007 |
| 7265098 | Polyacid/polyalkylene oxide gels and methods for their delivery The present invention relates to improved methods for delivering bioadhesive, bioresorbable, anti-adhesion compositions. Antiadhesion compositions can be made of intermacromolecular complexes of carboxyl-containing polysaccharides, polyethers, polyacids, polyalkylen... | 09/04/2007 |
| 7262181 | Water soluble cellulose etherified derivatives styptic materials The present invention relates to hemostatic materials made of water-soluble cellulose ether derivatives, such as methylcellulose, ethylcellulose, hydroxyethylcellulose, and pharmaceutically acceptable salts of carboxymethylcellulose, especially to hemostatic materia... | 08/28/2007 |
| 7259152 | Methods and compositions using sulodexide for the treatment of diabetic nephropathy The present invention provides oral formulations of Sulodexide for the treatment of diabetic nephropathy in patients with both insulin dependent and non-insulin dependent diabetes mellitus. Oral formulations containing doses adapted for administration to obtain a re... | 08/21/2007 |
| 7238677 | Prevention of urogenital infections The invention provides hyaluronic acid compounds and derivatives thereof for preventing urogenital infections by a variety of pathogens, as well as compositions, articles and methods for treating and preventing urogenital infections. ... | 07/03/2007 |
| 7238678 | Adhesive N,O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins The present invention relates to a method of inhibiting cellular and protein attachment to substrates by applying a composition containing an effective amount of adherent N,O-carboxymethylchitosan to a substrate with such that cellular and protein attachment are pre... | 07/03/2007 |
| 7235268 | Treatment of inflammatory bowel disease The present invention relates to compositions (including medicaments and nutritional products) for use in the prevention or treatment of Inflammatory Bowel Disease. Such compositions comprise a therapeutically effective amount of a soluble fibre derivable from fruit... | 06/26/2007 |
| 7235536 | Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections The invention relates to the treating, inhibiting or preventing of certain infectious agents including papilloma virus and various vaginitis-causing microbes by employing cellulose sulfate and other sulfated polysaccharides. In one embodiment, the method involves pr... | 06/26/2007 |
| 7226914 | Cellulose sulfate and other sulfated polysaccharides to prevent and treat papilloma virus infection and other infections A method for treating and preventing various infections, including papilloma virus and fungal and parasitic infections is provided. In particular, an effective amount of a sulphated polysaccharide, such as cellulose sulphate and dextran sulphate are administered to ... | 06/05/2007 |
| 7208593 | Self-cross-linked alkyl cellulose A process for producing a self-cross-linking alkyl cellulose derivative, which includes irradiating, with radioactive rays, a mixture of a starting alkyl cellulose derivative (the number of carbon atoms of the alkyl group is 1 through 3, the alkyl group may be subst... | 04/24/2007 |
| 7196073 | Imine-forming polysaccharide adjuvants and immunostimulants The present invention relates to polysaccharide conjugates that comprise: a polysaccharide that binds to surface-receptors present on Antigen Presenting Cells, conjugated to one or more compounds having stable carbonyl groups covalently attached, either directly or ... | 03/27/2007 |
| 7192984 | Compositions of polyacids and polyethers and methods for their use as dermal fillers The present invention relates to improved methods for filling the skin for cosmetic or medical purposes. Compositions comprising carboxymethyl cellulose (CMC), polyethylene oxide (PEO) and calcium ions can be made and have physical properties that depend on the amou... | 03/20/2007 |
| 7183266 | Dual induced viscosity fiber system and uses thereof The present invention relates generally to a method of blunting the postprandial glycemic response to a meal by feeding a dual induced viscosity fiber system. The first component of the induced viscosity fiber system is soluble fiber. The second component of the ind... | 02/27/2007 |
| 7160449 | Proline chiral columns with broad chiral selectivity A general chiral column with a multipleproline-based chiral stationary phase. Embodiments include chiral stationary phases of the following formula: wherein n is any integer of 2 or greater, and analogs and isome... | 01/09/2007 |
| 7160552 | Method of feeding a ruminant A method of feeding ruminants, the method including feeding a ruminant a fluid animal feed during a feeding period, the fluid animal feed including an animal feed component and the ruminant consuming greater than about 1.25 pounds of the animal feed component per da... | 01/09/2007 |
| 7151139 | Antimicrobial polymeric surfaces Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common material... | 12/19/2006 |
| 7144844 | Method of using viscoelastic vesicular fluids to enhance productivity of formations A process for enhancing the productivity of a formation consists of introducing into the formation a viscoelastic fluid which contains at least one surfactant, at least one quaternary amine polyelectrolyte, water, and a non-aqueous solvent. The surfactant forms aggr... | 12/05/2006 |
| 7141160 | Chiral columns with broad chiral selectivity A general chiral column with a multipleproline-based chiral stationary phase. Embodiments include chiral stationary phases of the following formula: wherein n is any integer of 2 or greater, and analogs and isome... | 11/28/2006 |
| 7132564 | Process for preparing cyclic ketones The present invention provides a process for preparing cyclic 1,3-keto esters in the absence of solvent, using solid-state or high viscosity reactors. ... | 11/07/2006 |
| 7115297 | Nutritionally fortified liquid composition with added value delivery systems/elements/additives A shelf-stable, ready to use, water-like composition for humans/animals; as an adjunct to fiber-water, and/or safe drinking water, consumed directly, tube feedings, or in the preparation/reconstitution of food(s)/beverage(s). Fortified Fiber-Water is fiber-water, wi... | 10/03/2006 |
| 7101862 | Hemostatic compositions and methods for controlling bleeding The invention provides hemostatic compositions useful to promote hemostasis at active bleeding wound sites. The hemostatic compositions typically include an article containing cellulose, e.g., cotton gauze, and a polysaccharide covalently linked to the cellulose, or... | 09/05/2006 |
| 7097860 | Method and composition for treatment of inflammatory and inflammation-related disorders A method of reducing inflammation in a variety of disorders by using an intraperitoneal solution of magnesium. The solution can be used for treating inflammatory and inflammation-related disorders in animals and/or humans. Application of the solution reduces inflamm... | 08/29/2006 |
| 7097855 | Transdermal thermal polymerization An invention for polymerizing or crosslinking a prepolymer using a water soluble, thermal polymerization initiator is disclosed. The prepolymer mixed with the initiator is injected or placed into an animal's body, and heat is applied over the site of the injection t... | 08/29/2006 |
| 7086403 | Condom with male genital desensitizer lubricant A condom having a first lubricating composition containing a male genitalia desensitizing agent on the inside surface thereof and a second lubricating composition on the outside surface thereof. The first lubricating composition has a higher viscosity than the secon... | 08/08/2006 |