Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 8048924 | Methods and compositions employing 4-aminophenylacetic acid compounds The invention provides compositions comprising 4-APAA compounds and methods for treating disorders involving inflammation of the intestinal system, such as inflammatory bowel disease. The methods and compositions of the invention also include combinations of 4-APAA ... | 11/01/2011 |
| 7763655 | Cosmetic compositions having carnitine creatinate and methods for using There is a topical composition having carnitine creatinate and a cosmetically acceptable vehicle. There is also provided a method for improving the aesthetic appearance of skin. There is also provided a method for inhibiting the induced lipid synthesis in skin. Ther... | 07/27/2010 |
| 7728038 | Methods for chelation therapy The invention relates to compositions and methods of treatment using an iron chelator, an antioxidant, estrogen, and/or combinations thereof, optionally, linked to a nanoparticle, to treat a subject in need thereof. The compositions and methods may be used to restor... | 06/01/2010 |
| 7700653 | Halogen-substituted aminodicarboxylic acid derivatives This invention relates to methods for treating cardiovascular disorders selected from heart failure, thromboembolic disorders, venous diseases, and fibriotic disorders other than fibrosis of the liver, comprising administering an effective amount of a compound of fo... | 04/20/2010 |
| 7488756 | Use of non-competitive and selective GluR5 antagonists as glutamate receptor modulating compounds This invention relates to the use of chemical compounds showing non-competitive and selective GluR5 antagonist or partial agonist activity for treating diseases that are responsive to modulation of an aspartate or a glutamate receptor. Moreover the invention provide... | 02/10/2009 |
| 7384979 | Substituted amino acids as erythropoietin mimetics This invention relates to a series of substitituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which ... | 06/10/2008 |
| 7378102 | Diclofenac sodium oral pharmaceutical The present invention relates to a diclofenac sodium oral pharmaceutical containing diclofenac sodium, a nonionic surfactant, a cholic acid derivative as an absorption promoting agent, and a glycerin or a glycol. The oral pharmaceutical has a rapid-acting eff... | 05/27/2008 |
| 7329777 | Methods for treating heart failure, thromboembolic disorders, and pulmonary fibrosis This invention relates to methods for treating heart failure, thromboembolic disorders, and pulmonary fibrosis, comprising administering an effective amount of a compound of formula (I) in which the several varia... | 02/12/2008 |
| 7323187 | Impregnation method The invention relates to a method for impregnating, incorporating or surface-treating substances/articles that can be microbially decomposed, contaminated and/or infested with parasites and/or that are perishable. The inventive method comprises the following steps: ... | 01/29/2008 |
| 7321000 | Ophthalmic composition containing N-acetyl-cysteine for the treatment of dry-eye syndrome An ophthalmic pharmaceutical composition containing acetylcysteine as the active ingredient having a mucolitic action, suitable for administration in eyedrops, where N-acetyl-cysteine is neutralised with base DEAE-dextrane in order to reach pH levels preferably betw... | 01/22/2008 |
| 7318930 | Control methods for boring bark beetles A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which... | 01/15/2008 |
| 7291596 | Pharmaceutical composition for thrombin peptide derivatives Disclosed are pharmaceutical compositions comprising a thrombin peptide derivatives and a chelating agent and/or a pharmaceutically acceptable thiol-containing compound. The pharmaceutical compositions optionally further comprise an antioxidant. Also, disclosed are ... | 11/06/2007 |
| 7252828 | Polysaccharide vaccine for infections The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. Th... | 08/07/2007 |
| 7238661 | Oral lactoferrin in the treatment of respiratory disorders The present invention relates to methods of treating an allergic or non-allergic respiratory disorder by administering orally a composition of lactoferrin alone or in combination with metal chelators to treat respiratory disorders. ... | 07/03/2007 |
| 7232830 | Method for treatment of neurodegenerative diseases and effects of aging A method for treatment of neurodegenerative disease conditions stemming from multiple sclerosis, aging, autoimmune diseases and fibromyalgia. A compound effective to increase neuronal metabolism of histamine to a histamine H2 agonist is administered in an... | 06/19/2007 |
| 7056950 | Compositions of biochemical compounds involved in bioenergy metabolism of cells A composition of biochemical compounds involved in bioenergy metabolism of cells and a method of use in prevention and therapy of diseases are disclosed. ... | 06/06/2006 |
| 7012096 | Composition for pain mediation and apparatus and method of use thereof The present invention is directed to a composition for treating burns. The composition comprises a therapeutically effective amount of one or more weak organic acid compatible with human skin, in a pharmacologically effective carrier delivered at a pH of about 2.5â€... | 03/14/2006 |
| 6984661 | Urea linker derivatives for use as PPAR modulators The present invention is directed to compounds of the structural formula (I), and pharmaceutically acceptable salts, solvates and hydrates thereof: Formula I (a) R1, R2 and R6 are each independently selected from the group consisting of hydrogen, C1-C | 01/10/2006 |
| 6906052 | Diagnosis and treatment of human kidney diseases Kidney disease is diagnosed by measuring urinary catalytic iron in humans. Progressive kidney disease is treated by administering an iron chelator to humans. In particular, the progression of kidney disease essentially can be halted and the severity of kidney diseas... | 06/14/2005 |
| 6875764 | Urea and thiourea compounds useful for treatment of coccidiosis The present invention relates to novel compounds, pharmaceutical compositions containing the same as well as a method for treatment of parasitic disorders, wherein said compounds are administered. The present compounds are especially well suited for treatment of coc... | 04/05/2005 |
| 6824794 | Method and apparatus for preventing bacteria and algae growth in water A water treatment agent and method of treating water to inhibit, reduce, or prevent the formation of algae and bacteria in a water body. The water treatment agent may include copper sulfate penta-hydrate and/or silver, di-sodium ethylene di-amine tetra-acetic acid d... | 11/30/2004 |
| 6814983 | Compositions and methods for nutrition supplementation The present invention relates to compositions comprising various vitamins and minerals and methods for using these compositions for nutritional supplementation in, for example, pregnant or lactating subjects. ... | 11/09/2004 |
| 6793914 | Anti-microbial compositions An anti-microbial composition employing: (i) a C1 to C4 monohydric alcohol carrier fluid, present at a level of at least 50% by weight of the total composition (excluding any volatile propellant present); (ii) an iron (III) chelat... | 09/21/2004 |
| 6784209 | Food supplement for increasing lean mass and strength Food supplement compositions and their methods of use in increasing lean mass and/or muscle size and/or strength in individuals, particularly, athletes is described. The food supplements described comprise a substance which increases nitric oxide production in the b... | 08/31/2004 |
| 6777436 | Intraocular tension lowering compositions for topical administration An intraocular tension lowering composition for topical administration is disclosed which comprises an effective amount of an (i) angiotensin II antagonist, (ii) a boric aid and (iii) an ethylenediamine tetraacetic acid. Said composition has excellent intraocular te... | 08/17/2004 |
| 6720356 | Magnesium di-potassium EDTA complex and method of administration A composition containing an EDTA complex in the form of a suppository is provided. More specifically, the EDTA complex is a magnesium di-potassium EDTA complex. The suppository may contain a controlled release agent which will release the EDTA complex over a period ... | 04/13/2004 |
| 6670397 | Methods for transdifferentiation of body tissues This invention relates to methods for transdifferentiation of body tissues which can be used to generate specific cell types needed for regenerating organs or body parts, following cellular degeneration, injury or amputation. The present invention also de... | 12/30/2003 |
| 6653322 | Therapeutic combinations of RAR antagonists and RXR agonists and use thereof The present invention provides compositions and methods for treating an animal, preferably a human, suffering from or predisposed to a physical disorder by administering an effective amount of a composition comprising at least one RAR antagonist, preferab... | 11/25/2003 |
| 6599940 | Synthesis of 2-hydroxymethylglutamic acid and congeners thereof One aspect of the present invention relates to 2-hydroxymethylglutamic acid and congeners thereof. A second aspect of the invention relates to a method of synthesizing 2-hydroxymethylglutamic acid and congeners thereof.... | 07/29/2003 |
| 6596752 | Inhibitors of 댔댡 mediated cell adhesion The present invention relates to small molecules according to the formula [I]: ##STR1## which are potent inhibitors of 댔ଲ.sub.1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing | 07/22/2003 |
| 6537590 | Solution and the method of making the same for the treatment of osteoarthritis A solution and the method of making the same for the treatment of osteoarthritis for treating symptoms of osteoarthritic conditions. The solution and the method of making the same for the treatment of osteoarthritis includes magnesium oxide; ethylenediami... | 03/25/2003 |
| 6534543 | Oxa acids and related compounds for treating skin conditions The present invention is directed to the use of compounds of Formula (I), as active principals for treating skin conditions and compositions containing these compounds ##STR1## wherein R4 is (CR5 R6 -CR7 R8... | 03/18/2003 |
| 6531510 | N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid in iron chelating therapy The use of a novel mono-cationic salt of N,N'-bis(2-hydroxybenzyl) ethylenediamine-N,N'-diacetic acid (HBED) in iron chelating therapy is disclosed. In particular, the invention relates to the subcutaneous use of a mono cationic salt of HBED for treating ... | 03/11/2003 |
| 6497892 | Cosmetic and skin protective compositions A hair and scalp formulation based on a peroxidase enzyme and synergistic yeast extract therefore. It entails a chemically-inert carrier material, a germicidal/preservative agent, and a metal chelating agent. A skin protective formulation based on peroxid... | 12/24/2002 |
| 6482849 | Inhibitors of 댔댡 mediated cell adhesion The present invention relates to small molecules according to the formula [I]: ##STR1## which are potent inhibitors of 댔ଲ.sub.1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing | 11/19/2002 |
| 6479528 | Methods for inhibiting or reversing tau filament formation polymerization Methods for inhibiting and/or reversing tau filament formation or polymerization are provided. These methods can be used for treating certain neurological disorders in vivo by administering pharmaceutical compositions which inhibit and/or reverse tau fila... | 11/12/2002 |
| 6469056 | Pharmaceutically active compounds, their preparation and use as ECE-inhibitors Pharmaceutically active compounds are prepared as described and used to produce pharmaceutical preparations for treating diseases.... | 10/22/2002 |
| 6468987 | Nutritional product for a person having ulcerative colitis An enteral nutritional product for a person having ulcerative colitis contains in combination (a) an oil blend which contains eicosapentaenoic acid (20:5n3) and/or docosahexaenoic acid (22:6n3), and (b) a source of indigestible carbohydrate which is metab... | 10/22/2002 |
| 6468965 | Pharmaceutical composition for oral administration of a mixture of chelating agents A solid pharmaceutical composition for the oral administration of chelating agents to an individual consists essentially of: at least 100 milligrams of ethylenediamninctetraacetic acid (EDTA) or a molar equivalent amount of pharmaceutically acceptable sal... | 10/22/2002 |
| 6465013 | Folic acid in solid dosage forms A nutritional tablet or caplet has a film coating that contains folic acid available for rapid release upon contact with gastric fluid. The film coating also includes a film forming polymer such as hydroxypropyl methylcellulose.... | 10/15/2002 |
