Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
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| Number | Title | Issue Date |
| 4438108 | Anti-thromboticum based on polysacharides, method for its preparation and pharmaceutical compositions A new anti-thromboticum based on a mixture of oligo- and polysaccharides is provided. The invention also relates to methods for preparation thereof and to pharmaceutical compositions including the said anti-thromboticum. The new product is of natural origin an... | 03/20/1984 |
| 4415490 | Non-thrombogenic material Non-thrombogenic material comprising a base polymer treated with heparin, the improvement in which the heparin is covalently bonded with the base polymer through only one acetal bond or hemiacetal bond at each bonding site between the heparin and the base... | 11/15/1983 |
| 4415559 | Anticoagulant An anticoagulant containing heparin having low antithrombin III affinity as an effective ingredient.... | 11/15/1983 |
| 4405612 | Heparin web compositions Microfibrous heparin salts, nonwoven webs of such fibers, a process for preparing the fibers and the use of the webs for the rapid heparinization of blood are disclosed.... | 09/20/1983 |
| 4402949 | Stable solutions of hydrogenated ergotalkaloids Stable solutions of (a) hydrogenated ergot alkaloids and (b) heparin as well as the salts thereof in a carrier medium comprising (c) water, (d) a mono- or poly-alcohol, and (e) urea or a pharmaceutically acceptable calcium or magnesium salt or ethylenedia... | 09/06/1983 |
| 4401758 | Process for making oligosaccharides having anti-Xa activity and the resulting oligosaccharides Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at least 30. They consist of chains substituted by no more than 8 ... | 08/30/1983 |
| 4401662 | Oligosaccharides having anti-Xa activity and pharmaceutical compositions containing them Oligosaccharides obtainable from heparin including heparinic constituents of molecular weights ranging from 2000 to 50,000. Said fractions have a Yin-Wessler titer and a USP titer in a ratio of at least 30. They consist of chains constituted by no more th... | 08/30/1983 |
| 4390532 | Topical combinations of an -estradiol with a methyl xanthine Topical compositions comprising an active ingredient selected from at least two of the following three classes of compounds: (a) N-methyl-substituted xanthines containing at least two methyl substituents; (b) -estradiol and certain derivatives thereof; ... | 06/28/1983 |
| 4362737 | Transdermal carrier materials Amphoteric dissociating complexes which have a cationic group having the structure ##STR1## wherein: R1 is an aliphatic alkyl group having 6 to 22 carbons, R2 is a member of the group consisting of --R4 --(CH2 ... | 12/07/1982 |
| 4331697 | Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative A heparin derivative in which at least 0.5% of the entire hydroxyl groups of heparin are in the form of an ester of the following formula ##STR1## wherein R1, R2 and R3 each represent a hydrogen atom or an alkyl group... | 05/25/1982 |
| 4329383 | Non-thrombogenic material comprising substrate which has been reacted with heparin Non-thrombogenic material comprising a base polymer treated with heparin, the improvement in which the heparin is covalently bonded with the base polymer through only one acetal bond or hemiacetal bond at each bonding site between the heparin and the base... | 05/11/1982 |
| 4326532 | Antithrombogenic articles A medical article having a layered antithrombogenic surface is useful as a polymeric implant. The article comprises a polymeric substrate coated with chitosan to which is appended an antithrombotic agent. A process for rendering the surface of a polymer a... | 04/27/1982 |
| 4315923 | Process for the production of organ extracts with high herparin content A process for producing an aqueous solution of high heparin content from heparin-containing animal organs comprises forming a heparin-enriched granular raw material from these organs and extracting the raw material at a temperature of 20° to 80° C. with... | 02/16/1982 |
| 4303651 | Heparin fragments having selective anticoagulation activity Heparin fragments having selective anticoagulation activity having 14-18 sugar units, the disaccharide unit L-iduronosyl-2-O-sulphate-N-sulpho-U-glucosamine-6-O-sulphate being the main component, and where unsulphated L-iduronic acid is in a position ... | 12/01/1981 |
| 4302368 | Nonthrombogenic articles and method of preparation The disclosure is of articles having reduced thrombogenicity and which are useful for purposes requiring their contact with whole blood. The articles comprise solid, polymeric resin substrates to which there is fixed a compound of the formula: ##STR1... | 11/24/1981 |
| 4301153 | Heparin preparation A heparin preparation which exhibits elevated anticoagulant activity and a process for producing the preparation. Conventional heparin exhibiting characteristic anticoagulant activity and molecular heterogeneity is incubated with antithrombin-heparin cofa... | 11/17/1981 |
| 4301028 | Control reagent for heparin activity determination A control reagent for heparin activity determination comprising 20 to 1500 USP heparin, 2000 to 30000 IU antithrombin III, 0.15 to 1.5 millimoles serum albumin, 0.005 to 0.05 mole ethylenediaminetetraacetic acid sodium salt, 0 to 0.4 mole saccharose, 2000 to 20000 U apr... | 11/17/1981 |
| 4276284 | Prevention of collagenase induced disease by treatment with collagenase inhibitors Certain ulcers and disease conditions resulting in tissue destruction, such as those found near the cornea of the eye, and those found in the stomach, and damaged joint tissue of rheumatoid arthritis, have been found to be caused by the enzyme, collagenas... | 06/30/1981 |
| 4265927 | Method of heparinizing a charged surface of a medical article intended for blood contact A charged surface of a medical article intended for blood contact can be heparinized by being contacted with a collodial aqueous solution of a complex compound of heparin and a cationic surfactant, the particles of the collodial solution having attached t... | 05/05/1981 |
| 4239664 | Anti-thrombogenic PVP-heparin polymer The present invention relates to a group of novel compounds defined as covalently bound poly-N-vinyl pyrrolidinone (PVP)-heparins. These compounds are synthesized on the basis of a novel concept that heparin molecules can be modified to have new desirable... | 12/16/1980 |
| 4239754 | Liposomes containing heparin and a process for obtaining them Heparin-based preparations wherein heparin is retained in or on liposomes. The lipids of said liposomes are preferably phospholipids comprising acyl chains derived from non saturated fatty acids, advantageously essential acids. These heparin-liposomes preparat... | 12/16/1980 |
| 4219520 | Method of making thrombo-resistant non-thrombogenic objects formed from a uniform mixture of a particulate resin and colloidal graphite The disclosure is that of an invention directed to new compositions of matter comprising a mixture of a resin in particulate form and colloidal graphite; and the use of such mixture to form objects of predetermined sizes and shapes, the exposed surfaces o... | 08/26/1980 |
| 4213962 | Artificial medical material with anticoagulative activity An artificial medical material with an anticoagulative activity which comprises a carrier material, and heparin and antithrombin III co-immobilized thereon by a per se conventional procedure.... | 07/22/1980 |
| 4118485 | Non-thrombogenic medical article and a method for its preparation A medical article is made non-thrombogenic by means of a surface coating containing heparin. The heparinized surface is stabilized by being contacted first with a cationic surfactant of the primary amine type and, subsequently, with a dialdehyde.... | 10/03/1978 |
| 4116898 | Non-thrombogenic articles The disclosure is of articles having reduced thrombogenicity and which are useful for purposes requiring their contact with whole blood. The articles comprise solid, polymeric resin substrates to which there is fixed a compound of the formula: ##STR1... | 09/26/1978 |
| 4073723 | Anti-coagulating and filtering blood Blood is passed through a heparin coated mass of filamentous polyester resin, polyamide resin, polyacrylic resin, glass, steel, cotton or cellulose. Thereafter the blood is passed through a mass of the same filamentous material which is not heparin coated... | 02/14/1978 |
| 4048064 | Biocompatible hemoperfusion system A biocompatible hemoperfusion system employing a polymer-coated detoxicant composition comprising a solid detoxicant having a semipermeable polymer coating which substantially retains free heparin is disclosed. The semipermeable polymer coating has an eff... | 09/13/1977 |
| 4039665 | Method for the eradication of venous blemishes A method for the eradication of venous blemishes, such as venous "spiders," "sunbursts," telangiectases, venous plexi and groups of dilated venules consists of sclerotherapy employing at least a 20% saline solution with heparin added as a sclerosing agent... | 08/02/1977 |
| 4029767 | Pharmaceutical compositions of stable urokinase-heparin complexes and methods for use thereof The present invention relates to pharmaceutical compositions of stable urokinase-heparin complexes, wherein the urokinase is purified, and methods for use thereof.... | 06/14/1977 |
| 3985871 | Pharmaceutical heparinoidic factor-containing composition and therapeutic use thereof A pharmaceutical composition comprising an anhydrous suspension of a heparinoidic factor in a suspending medium selected from vegetable and animal fats, aliphatic acids and their alkyl esters, in the presence of an anionic dispersant (typically sodium tau... | 10/12/1976 |
| 3932627 | Siver-heparin-allantoin complex Silver-heparin-allantoin complex and process for making same is disclosed. The silver-heparin-allantoin complex is prepared by a novel process in either powder or solution form. The silver-heparin-allantoin complex provides a non-thrombogenic, self-steril... | 01/13/1976 |