Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 8110605 | Compound for inactivating viruses and bacteria and method of making same The invention discloses a novel compound effective in inactivating viruses and bacteria. The compound, 2-(10-mercaptodecyl)-propanedioic acid or salts thereof, is shown to disrupt, break down or inactivate viruses and bacteria, thus suppressing infection and prolife... | 02/07/2012 |
| 8110604 | Methods and composition for treating a material A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agen... | 02/07/2012 |
| 8088825 | Fatty acid analogues for the treatment of inflammatory and autoimmune disorders The present invention relates to fatty acid analogues of the general formula R1-[xi-CH2]n—COOR2 and in particular to a method of treating inflammatory disorder selected from the group consisting of rheumatoid ... | 01/03/2012 |
| 8084500 | Method of using catalpic acid to treat dyslipidemia A method of treating and preventing dyslipidemia, cardiovascular disease, type 2 diabetes, obesity and other diseases associated with the Metabolic Syndrome and of increasing the expression of genes that promote lipid oxidation in an animal, including mammals and hu... | 12/27/2011 |
| 8039444 | Antisense permeation enhancers A pharmaceutical composition comprising an antisense oligonucleotide and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more function... | 10/18/2011 |
| 8039512 | Biologically active oils A process for the production of fats or oils and their extracts containing biologically active chemical compounds from a lipid substrate, the process comprising: a) inoculation of a lipid substrate with fungally derived lipolytic enzymes; b) incubating the inoculate... | 10/18/2011 |
| 7956092 | Non-toxic insecticide A non-toxic insecticidal composition includes a base horticultural oil, an emulsifier such as potassium salts of fatty acids, cinnamaldehyde and eugenol. ... | 06/07/2011 |
| 7939562 | Amphiphilic derivatives for the production of vesicles, micelles and complexants, and precursors thereof Amphiphilic derivatives composed of at least one fatty acid chain are derived from natural vegetable oils such as vernonia oil, lesquerella oil and castor oil, in which the several reactive groups such as epoxy, hydroxy and double bonds can be modified to polar and ... | 05/10/2011 |
| 7928143 | Method for preventing and/or treating neurodegenerative diseases The invention relates to a neurodegenerative disease treating agent for parenteral use, which comprises (2R)-2-propyloctanoic acid or a salt thereof. Since the neurodegenerative disease treating agent of the present invention comprising (2R)-2-propyloctanoic ... | 04/19/2011 |
| 7888391 | Method for reducing the severity of neurological disorders The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine metabolism selected from the group consisting of vitamin B12 and precursors thereof, vitamin B6 and derivatives ther... | 02/15/2011 |
| 7858662 | Medicament for the treatment of viral skin and tumour diseases The invention relates to a medicament containing a compound of general formula (1), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkynyl... | 12/28/2010 |
| 7851507 | Use of hydroxyoleic acid and related compounds in the manufacture of drugs Use of hydroxyoleic acid and its analogous compounds in the manufacture of drugs. Describes the use of hydroxyoleic acid and its analogs of general formula I: COOH—CHR—(CH2)m—CH═CH—(CH2)n—CH3, in whi... | 12/14/2010 |
| 7834058 | Method of using catalpic acid to treat hyperinsulinemia A method of treating hyperinsulinemia. The method includes administering a therapeutically effective amount of a compound selected from the group consisting of catalpic acid, glyceride esters thereof, pharmaceutically-suitable salts thereof, and combinations thereof... | 11/16/2010 |
| 7776916 | Nitrated lipids and methods of making and using thereof Described herein are nitrated lipids and methods of making and using the nitrated lipids. ... | 08/17/2010 |
| 7776915 | Topical formulations and methods of use A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrink... | 08/17/2010 |
| 7718698 | Process for decreasing environmental pollutants in an oil or a fat The invention relates to a process for decreasing the amount of environmental pollutants in a mixture comprising a fat or an oil, being edible or for use in cosmetics, the fat or oil containing the environmental pollutants, which process comprises the steps of addin... | 05/18/2010 |
| 7696247 | Lipid-based nitric oxide donors Novel nitric-oxide releasing lipid molecules are provided which comprise a lipid molecule selected from (a) phosphoglycerides, (b) lipids having a sphingosine base as a backbone, (c) monoacylglyerols, (d) diacylglycerols, (e) glycosylacylglycerols, and (f) sterol co... | 04/13/2010 |
| 7601757 | Lipid system and methods of use The present invention relates to a lipid system, and methods for using such a lipid system, containing specific relative ratios of omega-3, omega-6, and omega-9 fatty acids. The lipid system may be used independently or as a component of a nutritional product. A lip... | 10/13/2009 |
| 7582678 | Use of branched-chain fatty acids and derivatives thereof for the treatment of pain The present invention relates to compounds and pharmaceutical compositions useful for treating pain. The invention also relates to methods of treating or alleviating pain in mammals, comprising administering to a mammal suffering from pain, a pain-alleviating amount... | 09/01/2009 |
| 7579375 | Branched carboxylic acid compound and use thereof The present invention relates to a compound represented by formula (I) wherein R1 represents optionally protected hydroxy or oxo, indicates α-configuration, β-configuration or a mixture of these in an arbitrar... | 08/25/2009 |
| 7576130 | Dihydroxyl compounds and compositions for cholesterol management and related uses The present invention relates to novel dihydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascula... | 08/18/2009 |
| 7569608 | Pentanoic acid derivatives Formula (I) compounds: wherein R1 is alkyl substituted by fluorine(s); R2 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR3R4, in which R3, R4 is (i) hyd... | 08/04/2009 |
| 7569609 | Pentanoic acid derivatives Formula (I) compounds: wherein R1 is alkyl substituted by fluorine(s); R2 is hydroxy, alkoxy, alkoxy substituted by phenyl, NR3R4, in which R3, R4 is (i) hyd... | 08/04/2009 |
| 7553871 | Fatty acid antimicrobial The novel antimicrobial composition is disclosed including from about 60 to 95% of a lipophilic polar solvent such as propylene glycol, ethylene glycol, or isopropanol and from about 0.5 to 5% of a mixture of C8 to C14 fatty acids. Other consti... | 06/30/2009 |
| 7544714 | Lipid-amino acid conjugates and methods of use N-fatty acid-amino acid conjugates and J2 prostanoid-amino acid conjugates are disclosed along with methods for making such conjugates and methods of using these conjugates in the treatment of conditions that involve dysfunctional lipid metabolism, insuli... | 06/09/2009 |
| 7435725 | Oral compositions and methods for prevention, reduction and treatment of radiation injury An oral composition for the prevention, reduction or treatment of radiation injury including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants, optionally formulated in a pharmaceutically acceptable car... | 10/14/2008 |
| 7423066 | Methods, compounds, and compositions for reducing body fat and modulating fatty acid metabolism Methods, pharmaceutical compositions, and compounds for reducing body weight, modulating body lipid metabolism, and reducing food intake in mammals are provided. The compounds of the invention include fatty acid ethanolamide compounds, homologues and analogs of whic... | 09/09/2008 |
| 7414044 | Use of targeted oxidative therapeutic formulation in treatment of type 2 diabetes A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as d... | 08/19/2008 |
| 7402610 | Carbonyl compound containing long-chain branched alkyl group A carbonyl compound represented by the following formula [1], wherein X is hydrogen, a hydroxy group, an alkoxy group or a group derived from a polyol, and n, which is the same in each instance, is 4 to 30. Compositions com... | 07/22/2008 |
| 7384981 | Preparation for improving the action of receptors The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine metabolism selected from the group consisting of vitamin B12 and precursors thereof, vitamin B6 and derivatives ther... | 06/10/2008 |
| 7384647 | Composition and method for repelling moles, voles and gophers The present invention is a composition and method for repelling moles, voles, gophers, chipmunks and armadillos by applying a composition comprising castor oil, yellow grease and sodium lauryl sulfate to plant materials. ... | 06/10/2008 |
| 7378443 | Fatty acid analogues for the treatment of cancer A fatty acid analogue of the general formula: R1-[xi-CH2]n—COOR2, wherein R1 is: a C2-C24 alkene with one or more double bonds and/or with one or more triple bonds, and/or a C | 05/27/2008 |
| 7368249 | Methods and compositions for evaluation and modulation of fertility The present invention concerns compositions and methods for regulating or determining fertility in humans and animals. In various embodiments of the invention, LOX and other related enzymes can be used as fertility markers, contraceptive agents, or means of treating... | 05/06/2008 |
| 7358278 | Cellular phosphorylation potential enhancing compositions preparation and use thereof A pharmaceutical composition comprising as an active phosphorylation potential enhancing substance a pharmaceutically-acceptable salt of an alpha-keto carboxylic acid thereof alone or in combination with nicatinamide and creatine and, its use and products containing... | 04/15/2008 |
| 7348310 | Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them The invention relates to aplidine derivatives of the general formula: which are useful for the treatment of tumors. ... | 03/25/2008 |
| 7345093 | Methods of enhancing solubility of compounds This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions. ... | 03/18/2008 |
| 7342044 | Preservative blends containing quaternary ammonium compounds The present invention provides a biocidal composition comprising a synergistic mixture of certain quaternary ammonium biocides and one or more ketone acids, aromatic carboxylic acids, salts thereof, or mixtures thereof. ... | 03/11/2008 |
| 7323187 | Impregnation method The invention relates to a method for impregnating, incorporating or surface-treating substances/articles that can be microbially decomposed, contaminated and/or infested with parasites and/or that are perishable. The inventive method comprises the following steps: ... | 01/29/2008 |
| 7318930 | Control methods for boring bark beetles A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described. Additional tests have shown that beetles will not infest a tree which... | 01/15/2008 |
| 7307103 | Sodium dodecyl sulfate compositions for inactivating prions An antiseptic composition useful in destroying the infectivity of infectious proteins such as prions is disclosed. The antiseptic composition is preferably maintained at either a low pH of 4.0 or less or a high pH of 10.0 or more either of which allows for an enviro... | 12/11/2007 |
