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| Number | Title | Issue Date |
| 8178581 | Production of peracids using an enzyme having perhydrolysis activity A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. ... | 05/15/2012 |
| 8168675 | Compositions and methods for treating neurodegenerative diseases The present invention relates to compositions and methods for treating neurodegenerative diseases. In some embodiments, the present invention provides compositions for treating and preventing presbycusis. ... | 05/01/2012 |
| 8168676 | Production on peracids using an enzyme having perhydrolysis activity A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. ... | 05/01/2012 |
| 8163801 | Enzymatic production of peracids using perhydrolytic enzymes A process is provided to produce a concentrated aqueous peracid solution in situ using at least one enzyme having perhydrolase activity in the presence of hydrogen peroxide (at a concentration of at least 500 mM) under neutral to acidic reaction conditions from suit... | 04/24/2012 |
| 8163800 | PKC-activating compounds for the treatment of neurodegenerative diseases The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. Th... | 04/24/2012 |
| 8114908 | Production of peracids using an enzyme having perhydrolysis activity A process is provided for producing peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with an inorganic peroxide, such as hydrogen peroxide, in the presence of an enzyme catalyst having perhydrolysis activity. ... | 02/14/2012 |
| 8114907 | Method for treating a pulmonary disease state in mammals by up regulating indigenous in vivo levels of inflammatory agents in mammalian cells The present invention provides novel methods for treating a pulmonary disease state in mammals by up or down regulating indigenous in vivo levels of an inflammatory agent in mammalian cells comprising contacting the mammalian cells with a therapeutically effective a... | 02/14/2012 |
| 8110603 | Organic peracid polymer composition and process for producing the same It is intended to provide an organic peracid polymer composition which is stable, odorless and has sufficient water solubility and is suitably used as a bactericide, a bleaching agent and a cleaning agent. By mixing and dissolving an organic acid polymer, hydrogen p... | 02/07/2012 |
| 8093292 | Methods for the treatment of HIV-1 related fat maldistribution, fasting hyperlipidemia and modification of adipocyte physiology Methods for treating or preventing metabolic dysregulation of adipocytes resulting from HIV-1 infection or chronic inflammation are disclosed. The compositions contain a conjugated fatty acid, a thiol-containing compound and a bioavailable form of trivalent chromium... | 01/10/2012 |
| 8071645 | Systems and methods for treating human inflammatory and proliferative diseases and wounds, with fatty acid metabolism inhibitors and/or glycolytic inhibitors Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a fatty acid metabolism inhibitor, a glycolytic inhibitor, and/or an agent able to alter cellular production of reactive oxygen, or combination thereof, option... | 12/06/2011 |
| 8067469 | System for trapping flying insects with attractant lures The present application discloses a system for trapping flying insects, a first chemical lure such as lactic acid, a salt of lactic acid, or combinations thereof, and a second chemical lure comprising a source of ammonia. The lures may be employed in particular geom... | 11/29/2011 |
| 8030351 | Treatment of animal carcasses Described is a method of sanitizing animal carcasses using aqueous streams having an antimicrobial composition added to the stream. Preferably, the antimicrobial composition includes a mixture of one or more carboxylic acids having up to 18 carbon atoms and one or m... | 10/04/2011 |
| 8017651 | Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia Compositions for treating or preventing fat maldistribution or hyperlipidemia resulting from anti-retroviral treatment of HIV-1 infection are disclosed. The compositions contain a conjugated fatty acid or alcohol and at least one member selected from the group consi... | 09/13/2011 |
| 8013017 | Dermatological compositions and methods Dermatological compositions (methods of making and using) that include one or more anesthetic agents and/or one or more anti-inflammatory agents and/or a combination of ammonium, sodium, and potassium salts, preferably of an alpha-hydroxy acid. ... | 09/06/2011 |
| 7981933 | Method for treating an inflammation or lesion caused by a virus A method for treating an inflammation or lesion caused by herpesvirus, comprising topically applying to said inflammation or lesion a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust... | 07/19/2011 |
| 7964640 | Oligomers of straight-chain and unbranched fatty acids and drugs containing these The present invention relates to new substances which are derived from naturally occurring straight-chain and unbranched fatty acids and also from semi-synthetic and synthetic compounds with principally the same structure in that they represent dimers, trimers, tetr... | 06/21/2011 |
| 7910624 | Compositions for the treatment of blood disorders The invention relates to compositions containing chemical compounds and compositions containing steel factor which stimulate the expression of hemoglobin or globin protein such as embryonic or fetal globin, or the proliferation of hemoglobin expressing and other cel... | 03/22/2011 |
| 7902258 | Methods for preventing lesions caused by viruses of the Herpesviridae or Poxviridae family A method for preventing lesions caused by a virus of the Herpesviridae or Poxviridae family, comprising topically applying a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust the pH o... | 03/08/2011 |
| 7884132 | Process for metabolic control and high solute clearance and solutions for use therein The present disclosure describes novel standardized citrate replacement fluid solutions and a standardized dialysate solution for use with CRRT methods. The standardized citrate replacement fluid solutions and standardized dialysate solutions do not require modifica... | 02/08/2011 |
| 7858661 | Protein refolding agent and refolding method A refolding agent and refolding method which make it possible to produce high-purity proteins in high productivity. The refolding agent includes a phosphorus-containing compound (A) and an oxycarbonyl group-containing compound (B). The refolding method includes the ... | 12/28/2010 |
| 7851506 | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorde... | 12/14/2010 |
| 7838556 | Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands The present invention generally relates to pharmaceutical compositions comprising ethers of 3-hydroxyphenylacetic acid. The present invention also relates to therapeutic uses of the ethers of 3-hydroxyphenylacetic acid. The ethers of 3-hydroxyphenylacetic acid have ... | 11/23/2010 |
| 7834057 | Compositions and methods for skin treatment Compositions for the treatment of the skin. The compositions reduce and/or reverse the visible appearance of skin damage. In the preferred embodiment, the composition includes Retinyl Palmitate Polypeptide; Ascorbylmethylsilanol Pectinate; Tocopheryl Polypeptide; Ch... | 11/16/2010 |
| 7776914 | Esterified fatty acid composition The invention is directed to compositions comprising lecithin, olive oil, esterified fatty acids and mixed tocophenols for use in the treatment and prevention of various types of arthritis and other inflammatory joint conditions, periodontal diseases and psoriasis, ... | 08/17/2010 |
| 7741366 | Low pH pharmacologically active products and methods for the production thereof There is provided a new technology that will allow the formulation of pharmaceutically active organic acid products at relatively high pH during storage. This affords the advantages of avoiding formulation with the acid form of the product, yet when the product is u... | 06/22/2010 |
| 7741367 | Method of using abscisic acid to treat diseases and disorders The present invention provides compositions and methods for treating and/or preventing diseases and disorders associated with expression of PPAR γ and/or infiltration of macrophages into skeletal muscle tissue and/or white adipose tissue. The method treats such dis... | 06/22/2010 |
| 7723387 | Self-neutralizing acid peel for dermatologic use A dermatologic peel comprising alpha hydroxyl acid and metal hydroxide nanocomplexes as neutralizing agents to continually reduce the activity of the system when the acid and neutralizer components are mixed. For example, a 30% glycolic acid gel mixed with a fluidiz... | 05/25/2010 |
| 7718697 | Method for treating glaucoma comprising administering α-lipoic acid The present invention provides compositions and methods for treating glaucoma, ocular hypertension, and age-related macular degeneration. More specifically, the present invention describes the use of agents that down-regulate expression of tanis and/or p21Waf1/... | 05/18/2010 |
| 7709528 | Compounds, their preparation and use Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in th... | 05/04/2010 |
| 7705049 | Methods for treating non-melanoma cancers with PABA The present invention relates to a method for treating non-melanotic cancers by administration of PABA. The present invention also relates to the potentiation of standard cancer treatment of radiation, radioimmunotherapy, and/or chemotherapy using PABA. ... | 04/27/2010 |
| 7700651 | Preparations of phospholipids and pharmaceuticals containing 5-amino salicylic acid for the treatment of inflammatory bowel disease A unique composition of a 5-amino salicylic acid (5ASA) and a phospholipid is disclosed for treating Inflammatory Bowel Disease (IBD), where the composition can be a mixture, a molecular association complex or a covalent compound of 5ASA and a reactive phospholipid ... | 04/20/2010 |
| 7691905 | Inhibition of melanogenesis and melanoma metastasis with p-aminobenzoic acid (PABA) The present invention relates to the inhibition of melanogenesis with para-aminobenzoic acid (PABA) and its use in treating melanotic cancer. ... | 04/06/2010 |
| 7678831 | Butanoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic applications thereof Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and . processes for the prepar... | 03/16/2010 |
| 7666909 | Enhancement of alcohol metabolism D-glyceric acid has been found to enhance alcohol metabolism and thereby prevent adverse effects of alcohol consumption. D-glyceric acid is administered concurrently with alcohol, to accelerate the elimination of the alcohol from the body. D-glyceric acid is convert... | 02/23/2010 |
| 7662854 | HIF hydroxylase inhibitors The invention provides a compound of one of the formulae (A), (B), (C), (D), (E), (F) as herein defined, or a salt thereof, for use in the treatment of a condition associated with increased or decreased HIF levels or activity, or a condition in which an increase or ... | 02/16/2010 |
| 7619003 | Process for producing optically active compound A process for producing an optically active compound based on the hydrolysis of an alkenyl ester compound or the cleavage of an alkenyl ether compound. The process uses neither an acidic compound nor a basic compound, and reactants can be reacted in a high concentra... | 11/17/2009 |
| 7612111 | Esterified fatty acid composition The invention is directed to compositions comprising lecithin, olive oil, esterified fatty acids and mixed tocophenols for use in the treatment and prevention of various types of arthritis and other inflammatory joint conditions, periodontal diseases and psoriasis, ... | 11/03/2009 |
| 7547729 | 1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same The invention relates to substituted 1,3-diphenylprop-2-en-1-one derivative compounds, pharmaceutical and/or cosmetic compositions containing same, and the applications thereof in therapeutics and cosmetics. The invention also relates to a method for preparing said ... | 06/16/2009 |
| 7514471 | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor α (PPAR) The present invention provides the S enantiomer of a compound of formula (I) wherein n is 1 or 2 as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to processes for preparing such compounds, to their the utility in treati... | 04/07/2009 |
| 7504435 | Method for stimulating weight loss and/or for lowering triglycerides in patients Administration of a therapeutically effective amount of 3,5-diiodothyropropionic acid stimulates weight loss in patients, lowers triglyceride levels and reduces risk of death or progression of coronary heart disease in patients with metabolic syndrome. ... | 03/17/2009 |
