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Class 514/555 - Benzene ring in acid moiety


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the acid moiety contains a benzene
No. of patents: 119
Last issue date: 01/19/2010


1      
NumberTitleIssue Date
7649019Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a m...
01/19/2010
7390833Method for treating ADAMTS-5-associated disease
The present invention relates to methods of treating ADAMTS-5-associated diseases and particularly osteoarthritis comprising administering an agent capable of modulating ADMATS-5 activity to a subject afflicted with the disease. The agent is preferably a biaryl sulf...
06/24/2008
7309755Method of producing polycarbonate articles by rotation molding and rotation molded articles made by the method
A method for making a polycarbonate article is described wherein the article is made by rotation molding a melt polycarbonate having a weight average molecular weight from 25,000 to about 36,000. The melt polycarbonate is produced by transesterifying a diaryl carbon...
12/18/2007
7297817Thio-substituted arylmethanesulfinyl derivatives
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): wherein ...
11/20/2007
7161022Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative
A 4-phenyl-4-oxo-2-butenoate derivative is stably supplied in a short period of time, at low cost, in high purity and on an industrial scale by a process for producing the 4-phenyl-4-oxo-2-butenoate derivative, which comprises simultaneously or continuously reacting...
01/09/2007
7135497Treating neural conditions resulting from spinal cord contusions and other causes
β2-agonists, such as clenbuterol and salbutamol can enhance the recovery of locomotive function and/or neuromuscular strength following spinal cord injuries or as a result of degenerative neural conditions such as Mnd. Pharmacological compositions for tr...
11/14/2006
7101888Oral liquid tolterodine composition
A pharmaceutical composition in a form of an orally deliverable liquid comprises water having in solution therein a pharmaceutically acceptable water-soluble salt of a tolterodine related compound at a therapeutically effective concentration in the composition. The ...
09/05/2006
7067555Sertraline oral concentrate
The present invention provides an essentially nonaqueous, liquid pharmaceutical concentrate composition for oral administration containing sertraline or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients. The present in...
06/27/2006
7014864Formulations comprising lipid-regulating agents
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one structured lipid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation. ...
03/21/2006
7005449Tolterodine salts
The present invention concerns novel pharmaceutically active compounds, pharmaceutical compositions containing the same, the compounds for use as medicaments, and use of the compounds for the manufacture of specific medicaments. The present invention also concerns a...
02/28/2006
6984389Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M ...
01/10/2006
6982097Biocidal compositions and methods of using same
This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using the biocidal compositions for the disinfection of water that may conta...
01/03/2006
6855341Anti-viral compositions and methods of making and using the anti-viral compositions
Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involvi...
02/15/2005
6838091Formulations comprising lipid-regulating agents
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation. ...
01/04/2005
6750229Methods for treating skin pigmentation
This invention relates to methods and compositions for bringing about changes in skin pigmentation. More particularly, this invention relates to compounds which affect melanogenesis and can be used as depigmenting agents or as agents for darkening skin utilizing the...
06/15/2004
6730702Therapeutic agents for inflammatory diseases of intestine
The present invention provides a novel agent for prophylaxis or treatment of inflammatory bowel diseases for oral administration or intra-intestinal infusion, which comprises as an active ingredient a compound of the formula (I):
05/04/2004
6730667Iontophoresis disc pain blocker
Treatment of pain syndromes utilizes a topical polypharmaceutical preparation of phenoxybenzamine, ketamine, gabapentin, nifedipine, carbamazepine, or combinations of them. Other suitable components are blockers of sympathetic alpha 1, 2 and other receptors, NMDA re...
05/04/2004
6610689HIV protease inhibitors based on amino acid derivatives
A compound selected from the group consisting of a compound of formula I ##STR1## a compound of formula II ##STR2## and when the compound of formula I and II comprises an amino group pharmaceutically acceptable ammonium salts thereof, wherein R1
08/26/2003
6576664Inhibitors of aggrecanase and matrix metalloproteinases for the treatment of arthritis
This invention relates to molecules which inhibit metalloproteinases, including aggrecanase, and the production of tumor necrosis factor (TNF). In particular, the compounds are inhibitors of metalloproteinases involved in tissue degradation and inhibitors...
06/10/2003
6468554Sensorially active substance embedded in plastic
Denatonium benzoate (Bitrex™) dissolves in molten flexible polyvinyl chloride, imparting a bitter flavor to the plastic which discourages rats from gnawing on it. Denatonium benzoate can in all likelihood be added to polymers other than polyvinyl chlori...
10/22/2002
6372790Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the preparation of medicines intended to reduce hyperglycaemia
A pharmaceutical composition comprising: (i) metformin, optionally in the form one of its pharmaceutically acceptable salts; (ii) a fibrate selected from fenofibrate and bezafibrate; and optionally one or more pharmaceutically acceptable excipients, is su...
04/16/2002
6372789Bacteriocide compositions for agricultural and horticultural use
The novel agricultural and horticultural fungicidal compositions containing as active ingredients a combination of A) 1,1'-iminiodi(octamethylene)diguanidine of the formula ##STR1## (iminoctadine) or an acid addition salt thereof and B) 1,1'-iminiodi(octameth...
04/16/2002
6344479Method of preventing retinopathy of prematurity in a neonate
A method is disclosed of preventing retinopathy of prematurity in a prematurely born neonate susceptible to developing retinopathy of prematurity, which comprises the step of parenterally administering to said prematurely born neonate, a therapeutically e...
02/05/2002
6337080Insect control mat
An insect control mat having a heatable substrate; an insect control active material; and an aversion material in an amount effective to cause a person to avoid retaining the mat in the person's mouth. A method of controlling insects by use of such a mat ...
01/08/2002
6248782Method of treating viral diseases
A therapeutic process for treating disease in mammals caused by retroviruses in which the infected mammal is treated with a ribonucleotide reductase inhibitor such as a polyhydroxy benzoic, mandelic or phenylacetic acid derivative, such as N,3,4-trihydrox...
06/19/2001
6221907Tricyclic compounds having activity specific for integrins, particularly alphanubeta3 integrins, method for preparing same, intermediates therefor, use of said compounds as drugs, and pharmaceutical compositions containing same
The subject of the invention is the products of formula (I): ##STR1## in which R1, R2, R3, R4, R5 and G are as defined in the description, the dotted lines represent an optional second bond, as well a...
04/24/2001
6048849Formulations and methods of reducing toxicity of antineoplastic agents
This invention provides for pharmaceutical formulations of compounds which are useful as protective agents when administered to patients also receiving antineoplastic drugs. The invention also includes methods of reducing the toxicity of various antineopl...
04/11/2000
5998395Methods of treating inflammatory dermatosis
Inflammatory dermatoses are controlled and cleared by topical application to the affected areas of the skin of a composition containing both a corticosteroid and a retinoid. The combined therapy is more effective than either active ingredient alone and is...
12/07/1999
5939459Method and composition for treating mammalian disease caused by inflammatory response
A method for treating emphysema and other disease states in mammals caused by mammalian cells involved in the inflammatory response is disclosed. Mammalian cells participating in the inflammatory response are contacted with an inflammatory response mediat...
08/17/1999
5891856Method for protection against genotoxic mutagenesis
A method and pharmaceutical for protecting against mutational damage in mammalian cells, irrespective of the nature of the mutagenic event or source of radiational or chemical insult or the like....
04/06/1999
5863941Method and composition of a topical treatment of inner ear and labyrinth symptoms
Periauricularly administered topical therapy with a carrier system containing local anesthetics is a new and effective treatment of disorders of the inner ear and labyrinth, which has a low incidence of side effects. The use of this type of therapy applie...
01/26/1999
5811459Ortho substituted aromatic compounds useful as antagonists of the pain enhancing effects of E-type prostaglandins
The invention relates to compounds of the formula (I): ##STR1## wherein A, B and D are various ring systems such as phenyl, R1 includes carboxy, R3 is hydrogen or C1-4 alkyl and Z is a linking group such as --(CH(R
09/22/1998
5728734Pesticide preparation of aqueous suspension type
A pesticide preparation of aqueous suspension type which comprises: (a) a 1,1'-iminiodi(octamethylene)diguanidinium tris(alkyl-benzenesulfonate) as an active pesticide ingredient; (b) at least one dispersion stabilizer selected from among alcohols having a deg...
03/17/1998
5700833Isocarbacyclin derivatives
The present invention provides novel isocarbacyclin derivatives useful for search and study of prostacyclin receptor and as a therapeutic drug for central nervous system diseases, which derivatives are expressed by the following formula ›I!: ##STR1#...
12/23/1997
5681838Substituted amino compounds, their preparation and their use as inhibitors of thrombocyte-aggregation
The present invention relates to novel substituted amino compounds of the formula I: R1 -(A)a -(B)b -(D)c -(CH2)m -N(R2)-(CH2)n -R3 as defined in the ...
10/28/1997
5658954Whitefly insecticide
A specially formulated environmental insecticide is provided which effectively controls whiteflies and other insects but is safe to humans, farm animals, pets, crops, and fish. The cost-effective non-polluting insecticide can be in the form of a 100% conc...
08/19/1997
5637616Method for treating diseases mediated by proteases
A method for the topical or systemic treatment of disorders mediated by proteases which result in skin or mucosal lesions, and in particular, pemphigus, cicatricial pemphigoid, bullous pemphigoid, lichen planus, and canker sores, is disclosed wherein the ...
06/10/1997
5626838Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
The present invention provides novel methods for prevention or treatment of primary and recurring squamous cell carcinoma of the oral cavity or oropharynx comprising topical administration, to the oral cavity or oropharynx, of an effective amount of an NS...
05/06/1997
5614554Reverse transcriptase inhibitors and antiviral agents
The present invention provides a reverse transcriptase inhibitor and an antiviral agent comprising at least one member selected from the group consisting of sulfated tyrosines and physiologically acceptable salts thereof as an effective component; and exh...
03/25/1997
5614510Pharmaceutical composition with improved bioavailability of inositol phosphate
The invention relates to an inositol phosphate containing pharmaceutical composition which comprises a nitrogen-containing compound for improvement of the bioavailability of the inositol phosphate in mammals including man at non-parenteral administration....
03/25/1997
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