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| Number | Title | Issue Date |
| 8076373 | Method for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite The present invention provides a method for treating wounds and diseases in mammals, caused by mammalian cells involved in an inflammatory response, by altering indigenous in vivo levels of peroxynitrous acid, and salts thereof. The method comprises contacting the m... | 12/13/2011 |
| 8053472 | Use of the acetyl L-carnitine in association with the biotin for the treatment of patients with type 2 insulin-resistant diabetes mellitus The invention relates to the use of the acetyl L-carnitine in association with the biotin for the treatment of patients with Type 2 insulin-resistant diabetes mellitus. ... | 11/08/2011 |
| 8034840 | Guanylhydrazone salts, compositions, processes of making, and methods of using The invention relates to pharmaceutically acceptable salts of guanylhydrazone-containing compounds, for example, Semapimod. The invention also relates to pharmaceutically acceptable compositions comprising the salts and methods for their use. ... | 10/11/2011 |
| 7820715 | Crystal comprising (2R)-2-propyloctanoic acid and amine Crystals comprising (2R)-2-propyloctoic acid and an amine which retain the pharmacological effect of (2R)-2-propyloctoic acid and can be safely used as a medicinal raw drug for peroral solid preparations. Of these crystals, the crystals especially with dibenzylamine... | 10/26/2010 |
| 7820716 | Crystalline polymorphs of desvenlafaxine succinate and their preparations The present invention is directed to two new polymorph Form V and Form F of desvenlafaxine succinate, to processes of their preparations, pharmaceutical composition comprising such materials and their use in therapy. Form V is prepared from recrystallizing desvenlaf... | 10/26/2010 |
| 7786167 | Compositions containing prodrugs of florfenicol and methods of use The present invention provides compositions and methods for administering florfenicol to mammals. The compositions contain a prodrug of florfenicol in a pharmaceutically acceptable carrier. In one embodiment the prodrug is an esterized form of florfenicol. Examples ... | 08/31/2010 |
| 7767712 | Storage-stable aqueous composition comprising a magnesium compound and L-carnitine The present invention relates to a storage-stable aqueous or gel-like composition or solution comprising a magnesium compound selected from a magnesium salt or a magnesium complex compound, and L-carnitine, and the use thereof for the preparation of a medicament for... | 08/03/2010 |
| 7754765 | Copper chelators for treating ocular inflammation In various aspects, the invention provides methods for treating ocular inflammation using copper chelating compounds, such as compounds other than D-penicillamine. In some embodiments, such compounds may be polyamines, such as triethylenetetramine or tetraethylenepe... | 07/13/2010 |
| 7534816 | Amidobetaines for oral care applications An aqueous composition for oral care application comprising solution of an amidobetaine of the following general Formula I is disclosed; in which R is an alkyl of coconut fatty acids, preferably hydrogenated coconut fatt... | 05/19/2009 |
| 7439268 | Compositions containing prodrugs of florfenicol and methods of use The present invention provides compositions and methods for administering florfenicol to mammals. The compositions contain a prodrug of florfenicol in a pharmaceutically acceptable carrier. In one embodiment the prodrug is an esterized form of florfenicol. Examples ... | 10/21/2008 |
| 7410655 | Anticancer agent An anticancer agent containing platinum preparation, humic substances, water and sodium chloride. Potassium tetrachloroplatinate is used as a platinum compound and lignohumic acid ammonium salts are used as humic substances taken in the following ratio of com... | 08/12/2008 |
| 7371367 | Method of treating inflammatory acne vulgaris and rosacea with carbamide peroxide A method of treating inflammatory acne vulgaris or inflammatory acne rosacea comprises the topical application of a formulation incorporating carbamide peroxide in a pharmaceutically acceptable vehicle. Inflammatory acneform lesions that can be successfully treat wi... | 05/13/2008 |
| 7348362 | Bronchodilating β-agonist compositions and methods Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a derivative thereof. Methods for treatment, prevention, or amelioration o... | 03/25/2008 |
| 7335384 | Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith The present disclosure describes a novel composition for the treatment and/or prevention of neurogenic inflammation. Such composition is also useful in the treatment and/or prevention of disease states and conditions associated with neurogenic inflammation. Such dis... | 02/26/2008 |
| 7323163 | Film-forming compositions and methods Film-forming compositions, as well as methods of making and using, wherein the compositions include an optional active agent, water, a surfactant, and a water-soluble or water-dispersible vinyl polymer comprising amine group-containing side-chains and a copolymerize... | 01/29/2008 |
| 7309497 | Injectable pharmaceutical composition for systematic administration of pharmacologically active ingredients The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient i... | 12/18/2007 |
| 7309755 | Method of producing polycarbonate articles by rotation molding and rotation molded articles made by the method A method for making a polycarbonate article is described wherein the article is made by rotation molding a melt polycarbonate having a weight average molecular weight from 25,000 to about 36,000. The melt polycarbonate is produced by transesterifying a diaryl carbon... | 12/18/2007 |
| 7301050 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 11/27/2007 |
| 7291647 | Guanylhydrazone compounds, compositions, methods of making and using The present invention relates to compounds having the formula: salts thereof; compositions comprising one or more of the compounds and/or salts thereof; methods of using; and methods of m... | 11/06/2007 |
| 7291347 | Succinate salt of O-desmethyl-venlafaxine A novel salt of O-desmethyl venlafaxine is provided, O-desmethylvenlafaxine succinate. Pharmaceutical compositions, dosage forms and methods of use are also provided. ... | 11/06/2007 |
| 7285576 | Absorbent polymer compositions, medical articles, and methods An absorbent polymer composition, which can be in the form of a foam, that includes a polymeric material, absorbent particles and thermally expandable (or expanded) microspheres. ... | 10/23/2007 |
| 7244764 | Methods and compositions for treating amyloid-related diseases Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-+related disease. ... | 07/17/2007 |
| 7244765 | Guanylhydrazone salts, compositions, processes of making and methods of using The invention relates to pharmaceutically acceptable salts of guanylhydrazone-containing compounds, for example, Semapimod. The invention also relates to pharmaceutically acceptable compositions comprising the salts and methods for their use. ... | 07/17/2007 |
| 7226947 | Use of creatine as a fat substitute The invention relates to the use of creatine or creatine salts as a fat substitute to be given to breeding animals and feeder animals. The creatine or creatine salts are used as a substitute for flesh meal, fish meal and/or antimicrobial performance enhancers, growt... | 06/05/2007 |
| 7208615 | Triple mineral salts of (-)-hydroxycitric acid and processes for preparing the same This invention relates to novel triple salts of (−)-hydroxycitric acid having the general formula 1 wherein X, Y are selected from zinc or group IIA metal and Z is selected from group IA metal of the Periodic T... | 04/24/2007 |
| 7193108 | Phenylpropionic acid derivatives Specified phenylpropionic acid derivatives and analogues thereof have an antagonistic activity to α 4 integrin. They are used as therapeutic agents or preventive agents for various diseases concerning α 4 integrin, such as inflammatory diseases in which α 4 integ... | 03/20/2007 |
| 7182952 | Urea and nitrogen based compounds as feeding stimulants/aggregants and masking agents of unpalatable chemicals for subterranean termites Nitrogen containing compounds are effective as subterranean termite feeding stimulants/aggregants and as masking agents for concealing the presence of other compounds which are repellents to termites, when they are used in low concentrations, less than or equal to a... | 02/27/2007 |
| 7169770 | Method of enhancing reproductive performance in sows The present invention relates to supplementing the diets to sows during the periods of gestation, lactation, and breeding by feeding L-carnitine and chromium. The supplementation enhances pork productivity by increasing the number of pigs born alive in the subsequen... | 01/30/2007 |
| 7105699 | Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-n... | 09/12/2006 |
| 7087785 | Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-n... | 08/08/2006 |
| 7063865 | Composition and method for substantially reducing the deleterious effects of alcohol on the body A composition that will substantially reduce the deleterious effects of alcohol on the body and substantially reduce the side effects associated with hangovers (i.e. headaches, dizziness, nausea, dry mouth, etc) when taken as recommended. The composition includes an... | 06/20/2006 |
| 7052683 | Composition to detoxify formaldehyde in gaseous state, in aqueous solutions, and to protect human cell lines against formaldehyde A chemical compound is disclosed herein for performing a complex enzymatic neutralization and fixation of formaldehyde, providing a method for instantaneous neutralization of formaldehyde vapors and offering a complete and rapid control of incidental releases, and a... | 05/30/2006 |
| 7033992 | Formulations for IL-11 Provided by the present invention are novel compositions and methods for obtaining concentrated preparations of IL-11 and formulations of IL-11 suitable for storage and administration. ... | 04/25/2006 |
| 7029703 | Composition for promoting healthy bone structure A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, f... | 04/18/2006 |
| 7019031 | Anticancer agents based on regulation of protein prenylation Oncoproteins such as Ras and RhoB are known to induce cell division in an unrestrained manner when such proteins are localized at the inner surface of a cancer cell membrane. The localization is effected by the prenylation reaction, whereby a hydrophobic group (e.g.... | 03/28/2006 |
| 7001615 | Sustained release ophthalmic, otic and nasal suspension Sustained release suspension formulations for ophthalmic, otic and nasal administration are disclosed. The formulations comprise a basic active, a cation exchange resin, and a combination of a polymeric suspending agents to provide superior resuspendability. ... | 02/21/2006 |
| 6992037 | Precious metal catalyst for debenzylation One aspect of the invention relates to catalyst composite containing a metal catalyst and a specifically defined carbon support containing a carbonaceous material. For example, the carbon support may have a total pore surface area of about 800 m2/g or mor... | 01/31/2006 |
| 6982286 | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases The present invention is directed to carbocyclic hydrazino compounds that function as inhibitors of copper-containing amine oxidases commonly known as semicarbazide-sensitive amine oxidases (SSAO), including the human SSAO known as Vascular Adhesion Protein-I (VAP-1... | 01/03/2006 |
| 6982097 | Biocidal compositions and methods of using same This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using the biocidal compositions for the disinfection of water that may conta... | 01/03/2006 |
| 6967219 | Reversing or preventing premature vascular senescence Premature vascular senescence is reversed or prevented in tissue or cells by contacting the tissue or cells with a hydroxyguanidine. This finds application in treatment of patients with a disorder associated with elevated levels of advanced glycation end products in... | 11/22/2005 |
