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| Number | Title | Issue Date |
| 8178580 | Formulations and methods for treating amyloidosis Methods, formulations, and compositions for the treatment of amyloidosis are described. ... | 05/15/2012 |
| 8097651 | Diclofenac formulations and methods of use Methods and formulations are provided for treating migraine and other acute pain episodes using diclofenac, and formulations of diclofenac that provide both rapid and sustained relief from acute pain. Methods and formulations are also provided for treating symptoms ... | 01/17/2012 |
| 7939561 | Blister packaging for acute pain regimens Provided are rapidly bioavailable solid oral dosage forms of acute pain medications, and moisture resistant packaging that enables the formulation of such rapidly bioavailable tablet dosage forms. Also provided is packaging that discourages the use of rapidly bioava... | 05/10/2011 |
| 7812055 | Method for treating wood Described is a method and a composition for preparing wood, to its use and to the wooden product obtained by the method. The method and the composition use liquid or water-soluble organic ammonium carboxylate of formula (1): [NR1R2R3... | 10/12/2010 |
| 7759394 | Diclofenac formulations and methods of use Methods and formulations are provided for treating migraine and other acute pain episodes using diclofenac, and formulations of diclofenac that provide both rapid and sustained relief from acute pain. Methods and formulations are also provided for treating symptoms ... | 07/20/2010 |
| 7745489 | Compositions and methods for inhibition of phospholipase A2 mediated inflammation Specific, highly potent 2-oxo-amide based inhibitors of phospholipase A2 (PLA2) activity are provided. A role for PLA2 activity in spinally mediated inflammatory processes is established, and a method for treating hyperalgesia and ot... | 06/29/2010 |
| 7687542 | Rapidly bioavailable tablet and capsule formulations of diclofenac The present invention relates to excipients for the production of rapidly bioavailable solid oral dosage forms of diclofenac. In particular, the invention relates to the use of excipients that promote the bioavailability of such formulations, including alkaline buff... | 03/30/2010 |
| 7666908 | Method for enhancing cognitive function The present invention relates to method for enhancing cognitive function in a mammal, comprising administering to a mammal in need thereof an effective amount of a compound of the formula (I): Further, the present invention... | 02/23/2010 |
| 7605179 | Napthoquinone derivatives as inhibitors of tau aggregation for the treatment of alzheimer's and related neurodegenerative disorders Provided are napthoquinone-type compounds which can be used to modulate the aggregation of protein (e.g. tau) associated with neurodegenerative disease (e.g. Alzheimer's disease). Structure-function characteristics for oxidised and reduced napthoquinone-type compoun... | 10/20/2009 |
| 7557141 | Method of treating autoimmune diseases A method of treating an autoimmune disease (for example, Systemic Lupus Erythematosus) comprises administering to the subject a treatment effective amount of a histone hyperacetylating agent, or a pharmaceutically acceptable salt thereof. Methods of screening compou... | 07/07/2009 |
| 7482377 | Pharmaceutical compositions and methods of treatment based on diclofenac New pharmaceutical compositions for oral use containing diclofenac together with alkali metal bicarbonates in amounts of from 20 to 80 by weight with respect to diclofenac are described. These compositions are entirely palatable and free from any unpleasant taste or... | 01/27/2009 |
| 7439393 | Phenethanolamine derivatives for treatment of respiratory diseases The invention relates to 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol; and salts and solvates thereof, including those which are pharmaceutically acceptable, along with formulations thereof, combinations there... | 10/21/2008 |
| 7435408 | Porous particles comprising excipients for deep lung delivery Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm... | 10/14/2008 |
| 7414076 | Methods and compositions for treating amyloid-related diseases Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease. ... | 08/19/2008 |
| 7361787 | Phenethanolamine derivatives for treatment of respiratory diseases The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases ... | 04/22/2008 |
| 7355069 | Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance The present invention provides a compound of formula (I), wherein n is 0, 1 or 2 and R1 represents halo, a C1-4alkyl group which is optionally substituted by one or more fluoro, a C1-4alkoxy group which is optionally substituted by o... | 04/08/2008 |
| 7309755 | Method of producing polycarbonate articles by rotation molding and rotation molded articles made by the method A method for making a polycarbonate article is described wherein the article is made by rotation molding a melt polycarbonate having a weight average molecular weight from 25,000 to about 36,000. The melt polycarbonate is produced by transesterifying a diaryl carbon... | 12/18/2007 |
| 7268163 | Method for treating an inflammation or lesion caused by a virus A method for treating an inflammation or lesion caused by herpesvirus, comprising topically applying to said inflammation or lesion a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust... | 09/11/2007 |
| 7262219 | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorde... | 08/28/2007 |
| 7258875 | Compositions and methods for topical treatment of skin infection The present invention describes an extremely effective, simple, novel, inexpensive, safe and quick method to treat both acne and warts, each with a different etiology and different clinical symptoms, by topically applying an effective amount of one or more polyvalen... | 08/21/2007 |
| 7255882 | Enkephalinase inhibitor and GABA precursor loading as anti-anxiety compositions Benzodiazepine withdrawal induced anxiety is treated by administration of an enkephalinase inhibitor, and a gamma-aminobutyric acid (“GABA”) precursor, or an endorphin or enkephalin releaser. These components promote restoration of normal neurotransmitter functi... | 08/14/2007 |
| 7253139 | Surfactant preparations comprising α-hydroxy acids A process for enhancing skin, mucous membranes and textile compatibility with an anionic surfactant composition involving: (a) providing an anionic surfactant composition; (b) providing an acid selected from the group consisting of a hydroxycarboxylic acid, a salt o... | 08/07/2007 |
| 7235687 | Derivatives of 4,4′-dithiobis-(3-aminobutane-1-sulfphonates) and compositions containing same The invention relates to the bis-hydrochloride of 4,4′-dithiobis-(3-aminobutane-1-sodium sulphonate) and the bis-trifluoracetate of 4,4′-dithiobis-(3-aminobutane-1-sulphonate of 2,2-dimethylpropyl). The invention also relates to a pharmaceutical composition comp... | 06/26/2007 |
| 7227031 | Prevention of neutrophil recruitment Aspirin (ASA) triggers a switch in the biosynthesis of lipid mediators, inhibiting prostanoid production and initiating 15-epi-lipoxin generation, through the acetylation of cyclooxygenase II. ... | 06/05/2007 |
| 7220779 | Swine growth promoters and method of promoting swine growth A pig growth enhancer, which comprises, as an active ingredient, at least one compound selected from 5-aminolevulinic acid, a derivative thereof and a salt thereof, and a method for enhancing pig growth, which comprises administering the growth enhancer to a pig. | 05/22/2007 |
| 7201914 | Combination antiperspirant and antimicrobial composition New medicaments and compositions having an antiperspirant agent and an antimicrobial agent, and methods based thereof, for control, prevention, amelioration, or treatment of perspiration and topical microbial contamination or infection of skin of the hands, feet, gr... | 04/10/2007 |
| 7192940 | Ether compounds The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a compo... | 03/20/2007 |
| 7189747 | Method of treating noninflammatory cartilage damage The invention relates to a method of preventing or treating cartilage damage by administering a GABA analog such as, for example, a compound of Formula and pharmaceutically acceptable salts thereof, wherein R | 03/13/2007 |
| 7186705 | Process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives The present invention relates to a process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives of the formula I, which are valuable pharmaceutical active ingredients and can be used, for exa... | 03/06/2007 |
| 7173019 | Linked cyclitols and their polysulfated derivatives The invention relates to compounds of the following formula (I). In these compounds, R1, R2, R3 and R4 are each independently a substituted or unsubstituted cyclitol with a ring comprising six carbon atoms, or hydrogen, su... | 02/06/2007 |
| 7172586 | Method of inotropic treatment of circulatory failure using hypothermia A method for treating cardiac failure such as congestive heart failure by application of hypothermia. Hypothermia may be applied by endovascular cooling using a heat exchange catheter circulating heat exchange fluid between an external heat exchanger controlled usin... | 02/06/2007 |
| 7169810 | Guanidine and amidine acid derivatives and analogs and methods of using the same The present invention releates to certain novel guanidine or amidine acid derivatives and analogs, to a process for preparing such compounds, having the utility in clinical conditions associated with insulin resistance, to methods for their therapeutic use and to ph... | 01/30/2007 |
| 7153886 | Method for treatment of peripheral inflammation of a loop ileal artificial anus The present invention provides a novel agent for prophylaxis or treatment of inflammatory bowel diseases for oral administration or intra-intestinal infusion, which comprises as an active ingredient a compound of the formula (I): | 12/26/2006 |
| 7067555 | Sertraline oral concentrate The present invention provides an essentially nonaqueous, liquid pharmaceutical concentrate composition for oral administration containing sertraline or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients. The present in... | 06/27/2006 |
| 7056938 | Method for scavenging radicals with urocanic acid, derivatives and analogues Upon exposure to UVB, the epidermal component trans-urocanic acid is not only photoisomerized into cis-urocanic acid, but will also, at least in part, be photooxidized into urocanic acid oxidation products. We hypothesized that urocanic acid oxidation products can m... | 06/06/2006 |
| 7056950 | Compositions of biochemical compounds involved in bioenergy metabolism of cells A composition of biochemical compounds involved in bioenergy metabolism of cells and a method of use in prevention and therapy of diseases are disclosed. ... | 06/06/2006 |
| 7053150 | Segmented polymers and their conjugates Segmented water soluble polymers, containing a higher molecular weight segment linked to a lower molecular weight segment, are described. In one embodiment, the polymer segments are poly(ethylene glycol) segments. The segmented polymers are functionalized and are us... | 05/30/2006 |
| 7045138 | Composition for mitigation of insects and/or mollusca A composition including a bait and a borate is used to mitigate a population of target insects and/or mollusca. The composition may include attractive by-products of agriculture and manufacturing with or without semiochemicals or biopesticides prepared as point sour... | 05/16/2006 |
| 7045150 | Tellurium containing nutrient formulation and process for enhancing the cumulative weight gain or feed efficacy in poultry A novel nutrient formulation containing tellurium for use in poultry, and a method of feeding it which improves subsequent livability, cumulative feed efficacy or weight gain is disclosed. ... | 05/16/2006 |
| 7045548 | Methods of inactivating viruses A method of inactivating viruses comprises contacting the virus with a virucidally effective amount of a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust the pH of the composition to... | 05/16/2006 |
