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| Number | Title | Issue Date |
| 7981932 | Salts of alkyl esters of sulfonated dicarboxylic acids and compositions containing same A salt of a mono- and/or dialkyl ester of a sulfonated dicarboxylic acid is provided, where the dicarboxylic acid contains 4 to 8 carbon atoms and the alkyl groups are derived from 2-propylheptanol. A composition including (a) one or more salt(s) of a mono- and/or d... | 07/19/2011 |
| 7956091 | Use of carnitines for the prevention and/or treatment of disorders caused by the andropause The use of propionyl L-carnitine in combination with acetyl L-carnitine, or one of their pharmaceutically acceptable salts, is disclosed for the preparation of a medicament, or of a nutritional supplement, for the prevention and/or treatment of the disorders of the ... | 06/07/2011 |
| 7776913 | Carnitines for treating or preventing disorders caused by andropause L-carnitine, propionyl L-carnitine and/or acetyl L-carnitine are used to prevent or treat disorders of male andropause caused by ageing or by chemical or surgical castration. ... | 08/17/2010 |
| 7385086 | Antimicrobial compounds This invention provides compounds and methods for treating, with said compound, a mycobacterial infection by administering to an animal a pharmaceutical composition containing a compound having the formula R—SOn-Z-CO—Y, where R is an alkyl groups havi... | 06/10/2008 |
| 7378443 | Fatty acid analogues for the treatment of cancer A fatty acid analogue of the general formula: R1-[xi-CH2]n—COOR2, wherein R1 is: a C2-C24 alkene with one or more double bonds and/or with one or more triple bonds, and/or a C | 05/27/2008 |
| 7294651 | Inhibition of exoprotein production using isoprenoid compositions Methods and compositions for inhibiting the production of exotoxins are disclosed. The compositions include an effective amount of an isoprenoid inhibitory compound to substantially inhibit the production of exotoxins by Gram positive bacteria. ... | 11/13/2007 |
| 7230029 | Fatty acid analogues for the treatment of proliferative skin disorders The present invention relates to fatty acid analogues of the general formula (I): R1-[xi-CH2]n—COOR2 wherein R1 is; a C1–C24 alkene with one or more double bonds and/or with ... | 06/12/2007 |
| RE39576 | Enzyme inhibitors A compound of formula (I) wherein R1 is a C1-6 straight or branched chain alkyl group, a C2-6alkenyl group, a C2-6 alkynyl group, a C3-6cyc... | 04/17/2007 |
| 7199156 | Composition and method to treat solid tumors A method to treat an animal, including a human, having a solid tumor. The method provides a lipophilic lathyrogen. The method administers a therapeutically effective amount of the lipophilic lathyrogen within the solid tumor. ... | 04/03/2007 |
| RE39403 | Method for supplying bioavailable methionine to a cow The present invention relates to a method for supplying bioavailable methionine to a cow which comprises supplying to the cow an ester of methionine or methionine amide and/or an ester of the hydroxy analogue of methionine or a salt thereof. ... | 11/14/2006 |
| 7105570 | Cysteine derivatives Objects of the present invention are to provide an oxidative stress inhibitor which is capable of suppressing the expression of a cytotoxic protein and the activation of a gene transcriptional regulatory factor taking part such expression of a cytotoxic protein and ... | 09/12/2006 |
| 7030158 | Therapeutic compounds A group of new compounds, N-(all-trans-Retinoyl)-L-cysteic acid, N-(13-cis-Retinoyl)-L-cysteic acid, N-(all-trans-Retinoyl)-L-cysteinesulfinic acid, N-(13-cis-Retinoyl)-L-cysteinesulfinic acid, N-(all-trans-Retinoyl)-L-homocysteic acid, N-(13-cis-Retinoyl)-L-homocys... | 04/18/2006 |
| 7026356 | Fatty acid analogues for the treatment of diseases caused by the pathological proliferation of smooth muscle cells The present invention relates to novel fatty acid analogues of the general formula (I): CH3—[CH2]m—[xi—CH2]n—COOR, wherein n is an integer from 1 to 12, and wherein m is an integer from 0 to 2... | 04/11/2006 |
| 6946474 | Nitrogen-containing compounds and their use as glycine transport inhibitors The present invention provides trichloroethyl-sulfonylurea-containing compounds that inhibit glycing transporters, pharmaceutical compositions comprising such compounds, methods for using such compounds for inhibiting glycine transporters and methods for using such ... | 09/20/2005 |
| 6916850 | Pyruvate derivatives Certain known and novel pyruvate derivatives are particularly active in restoring or preserving metabolic integrity in oxidatively competent cells that have been subjected to oxygen deprivation. These pyruvate-derived compounds include, but are not limited to oximes... | 07/12/2005 |
| 6903052 | Nematicidal compositions and methods The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled using the methods and composition of this invention. Certain of the us... | 06/07/2005 |
| 6872749 | Method for supplying bioavailable methionine to a cow The present invention relates to a method for supplying bioavailable methionine to a cow which comprises supplying to the cow an ester of methionine or methionine amide and/or an ester of the hydroxy analogue of methionine or a salt thereof. ... | 03/29/2005 |
| 6852756 | Use of pleuromutilin derivatives for transdermal treatment of bacterial diseases Described is a method for transdermally controlling a bacterial infection in a non-human animal which comprises the step of topically applying to the non-human animal a medicament comprising valnemulin in free base or a pharmaceutically acceptable salt form. ... | 02/08/2005 |
| 6814988 | Process for optimizing milk production A method of supplying a ruminant with its nutritional requirements for methionine is provided wherein a hydroxy analogue of methionine that is available for absorption by a ruminant is administered to the ruminant. Preferably, the, ruminant is administered an isopro... | 11/09/2004 |
| 6806261 | Methods for treating certain diseases using naaladase inhibitors The present invention relates to methods for regulating the release of TGF-β from living cells in vitro or in vivo, comprising bringing the cells into contact with an effective amount of a NAALADase inhibitor. Such methods are believed to be useful for affecting ne... | 10/19/2004 |
| 6803057 | Hydrogen peroxide disinfectant with increased activity An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations contain about 0.5% wt./wt. % H2O2. The solution also contains from 0.05 to... | 10/12/2004 |
| 6777443 | Dipeptide derivatives Compounds of the formula wherein R, R1, COOR2, R3-R7, alk, and X have meaning as defined, such being useful as dual inhibitors of angiotensin converting enzyme and neutral endo... | 08/17/2004 |
| 6638978 | Antimicrobial preservative compositions and methods The present invention discloses an antimicrobial preservative composition and methods of using the same. The antimicrobial preservative composition includes a glycerol fatty acid ester, a binary mixture of fatty acids including a first fatty acid antimicr... | 10/28/2003 |
| 6552079 | Integrin antagonists Novel compounds, their salts and compositions related thereto having activity against mammalian integrins are disclosed. The compounds are useful in vitro or in vivo for preventing or treating thrombotic or restenotic disorders.... | 04/22/2003 |
| 6534495 | Serine protease inhibitors ##STR1## The invention relates to a compound having the formula (I): R1 SO2 --B--X--Z--C(O)--Y, B is a bond, an amino acid of the formula --NR--CH[(CH2)p C(O)OH]--C(O)-- or an ester derivative thereof wherein p ... | 03/18/2003 |
| 6528541 | Method for supplying bioavailable methionine to a cow The present invention relates to a method for supplying bioavailable methionine to a cow which comprises supplying to the cow an ester of methionine or methionine amide and/or an ester of the hydroxy analogue of methionine or a salt thereof.... | 03/04/2003 |
| 6525097 | Method of treating a cancerous condition by enhancing the effectiveness of the human immune system There is disclosed a method of treating a cancerous condition in a person in need of such treatment, which comprises enhancing the effectiveness of the person's immune system by the administration to such person of at least one aliphatic sulfur compound, ... | 02/25/2003 |
| 6458850 | Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or hyperlipidemia. Combinations disclosed include a fibric acid... | 10/01/2002 |
| 6444657 | Methods for treating certain diseases using naaladase inhibitors The present invention relates to methods of using NAALADase inhibitors to regulate TGF-ଲ and to treat neurodegenerative disorders, extracellular matrix formation disorders, cell-growth related diseases, infectious diseases, immune related diseases, ... | 09/03/2002 |
| 6441036 | Fatty analogues for the treatment of obesity, hypertension and fatty liver The present invention relates to novel fatty acid analogous of the general forumla I: CH3 --[CH2 ]m --[xi --CH2 ]n --COOR, as defined in the specification, which can be used for the treatme... | 08/27/2002 |
| 6420429 | Brain targeted low molecular weight hydrophobic antioxidant compounds Novel brain targeted low molecular weight, hydrophobic antioxidants and use of antioxidants in treatment of central nervous system neurodegenerative disorders such as Parkinson's, Alzheimer's and Creutzfeldt-Jakob's diseases and in treatment of conditions... | 07/16/2002 |
| 6417232 | Fatty acid analogues for the treatment of primary and secondary restenosis The present invention relates to novel fatty acid analogues of the general formula (I): CH3 --[CH2 ]m --[Xi --CH2 ]n --COOR, wherein n is an integer from 1 to 12, and wherein m is an integer ... | 07/09/2002 |
| 6399628 | N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting alpha- amyloid peptide release and/or its synthesis by use of such compounds Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid... | 06/04/2002 |
| 6372788 | Method for supplying bioavailable methionine to a cow The present invention relates to a method for supplying bioavailable methionine to a cow which comprises supplying to the cow an ester of methionine or methionine amide and/or an ester of the hydroxy analogue of methionine or a salt thereof.... | 04/16/2002 |
| 6369106 | Treatment of ischemic brain injuries with brain targeted anti oxidant compounds A method of reducing oxidative stress in the brain of an organism having a blood brain barrier and suffering an ischemic brain injury, the method comprising the step of administering a compound to the organism, the compound having (a) a combination of mol... | 04/09/2002 |
| 6365628 | Fatty analogues for the treatment of diabetes The present invention relates to novel fatty acid analogues of the general formula (I): CH3 --[CH2 ]m --[xi --CH2 ]n --COOR, as defined in the specification, which can be used for the treat... | 04/02/2002 |
| 6353012 | 15-Hydroxyeicosatetraenoic acid-related compounds and methods of use HETE derivatives and methods of their use for treating dry eye are disclosed.... | 03/05/2002 |
| 6284792 | Formulation of valnemulin The preparation of an improved galenic delivery form of valnemulin, which is notable for its good tolerance and stability in storage, is described. The new delivery form in question is a non-aqueous or oily injection formulation, which is obtainable by me... | 09/04/2001 |
| 6284258 | Long-acting, chemical-resistant skin emollients, moisturizers, and strengtheners The present invention relates to compounds that are two-part molecules, and compositions containing such compounds, in which one part is designed to become covalently bonded to the skin (bonding agent) and the other part (a characteristic use agent) is de... | 09/04/2001 |
| 6277883 | Method of treating male impotence by enhancing the effectiveness of the human immune system There is disclosed a method of treating male impotence in a person in need of such treatment, which comprises enhancing the effectiveness of the person's immune system by the administration to such person of at least one aliphatic sulfur compound, prefera... | 08/21/2001 |
