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| Number | Title | Issue Date |
| 8158679 | Use of L-carnitine for the preparation of a medicament in the form of eye-drops for treating corneal diseases Use of L-carnitine or a pharmaceutically acceptable salt thereof, for the preparation of an ophthalmic physiological supplement or medicament in the form of eye-drops, for the treatment of corneal oedema. ... | 04/17/2012 |
| 8119689 | Adjuvants on the basis of bisacyloxypropylcystene conjugates and derivatives and their uses in pharmaceutical compositions Bisacyloxycysteine type conjugates have been found to be useful as adjuvants and/or immunomodulators for prophylactic and/or therapeutic vaccination in the treatment of infectious diseases, inflammatory diseases, autoimmune diseases, tumors, and allergies, as well a... | 02/21/2012 |
| 8067467 | Thiosuccinic acid derivatives and the use thereof The present invention relates to compounds of the formula (I) wherein X1 and X2 independently represent O, NH or S, R1 and R2 are independently selected from the group consisting of a C1-C30 hydrocarb... | 11/29/2011 |
| 8067468 | L-carnitine and alkanoyl L-carnitine phytates and process for preparing the same Salts of L-carnitine and alkanoyl L-carnitines with phytic acid of general formula (I), and the process of preparing the same, wherein the mole ratio between the L-carnitine or its alkanoyl derivatives cation and phytic acid anion be within the range of 1:1 to 6:1, ... | 11/29/2011 |
| 8030350 | Trans carotenoids, their synthesis, formulation and uses The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals includ... | 10/04/2011 |
| 8013016 | Use of acetyl L-carnitine for the treatment of fibromyalgic syndrome The use of acetyl L-carnitine or one of its pharmaceutically acceptable salts is described for the preparation of a medicament and/or dietetic product for the treatment of fibromyalgic syndrome. ... | 09/06/2011 |
| 7973006 | Antibacterial agent based on fatty acid esters of hydroxy carboxylic acid acids The present invention relates to an antibacterial composition based on a combination of fatty acid ester of fatty acid and hydroxy carboxylic acid with an antibacterial agent selected from polylysine, protamine, their salts and mixtures hereof. The hydroxy carboxyli... | 07/05/2011 |
| 7956090 | Composition and method for increasing the anabolic state of muscle cells A nutritional supplement comprising at least a therapeutically effective amount of ethyl pyruvate and a therapeutically effective amount of at least one α-hydroxy branched-chain amino acid metabolite is provided by the present invention. The ingredients of the pres... | 06/07/2011 |
| 7947736 | Oligomeric compounds Method for the synthesis of a compound of formula H(OCH[CH3]CH2C[O])3—O-A-O—R wherein A is the residue of 1,3-butandiol and R is H or H(OCH[CH3]CH2C[O]3—. The method comprises reacting a cyclic ... | 05/24/2011 |
| 7919527 | Bipolar trans carotenoid salts and their uses The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.... | 04/05/2011 |
| 7915310 | Utilization of dialkylfumarates The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For ... | 03/29/2011 |
| 7897641 | Composition for the prevention and/or treatment of the cytotoxic effects induced by the use of immunosuppressive agents A composition is disclosed which is suitable for the prevention and/or treatment of cell and tissue abnormalities of exogenous, toxic or metabolic origin and suitable for reducing the toxic effects of cyclosporin-A and other immunosuppressive agents, which may take ... | 03/01/2011 |
| 7897642 | Compositions and methods for dry eye syndrome Compositions and methods to inhibit dry eye as well as other conditions are provided. ... | 03/01/2011 |
| 7872046 | Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use A crystalline form of a (3S)-aminomethyl-5-hexanoic acid prodrug and methods of preparing a crystalline form of a (3S)-aminomethyl-5-hexanoic acid prodrug, and methods of using a crystalline form of a (3S)-aminomethyl-5-hexanoic acid prodrug are provided. ... | 01/18/2011 |
| 7868043 | Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use Mesophasic forms of (3S)-aminomethyl-5-hexanoic acid prodrugs and methods of preparing and methods of using mesophasic forms of (3S)-aminomethyl-5-hexanoic acid prodrugs are provided. ... | 01/11/2011 |
| 7846969 | Ceramide emulsions A process for the production of a stabilized ceramide emulsion by adding one or more ceramides of Formula (2) to one or more sphingosines of Formula (1), and then adding an acidic compound and water to form one or more sphingosine salts, wherein the sphingosine salt... | 12/07/2010 |
| 7842726 | Carnitine derivative, salt thereof, external skin preparation and cosmetic material To provide novel carnitine derivatives and salts thereof that are resistant to hydrolysis in the presence of aqueous media, and also provide external skin preparations and cosmetics that are excellent in storage stability, product life, skin affinity and percutaneou... | 11/30/2010 |
| 7803840 | Utilization of dialkylfumarates The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For ... | 09/28/2010 |
| 7723386 | Lipid-improving agent and composition containing lipid-improving agent A lipid-improving agent containing a triglyceride(s) where a poly-unsaturated fatty acid is bonded to 2-position of a triglyceride(s). ... | 05/25/2010 |
| 7662853 | Monoacetyldiacylglycerol derivative for the treatment of sepsis The uses of mono acetyl diacyl glycerol derivatives extracted from deer antler for immunomodulating agent disclosed. Medical supplies and health foods containing the same as an effective ingredient also disclosed. Mono acetyl diacyl glycerol derivatives shows signif... | 02/16/2010 |
| 7655698 | Use of L-carnitine or of alkanoyl L-carnitines for the preparation of a physiological supplement or medicament for opthalmic use in the form of eye drops Use of L-carnitine and/or of one or more alkanoyl L-carnitines or one of their pharmaceutically acceptable salts for the preparation of an ophthalmic physiological supplement or medicament in the form of eye-drops, for the treatment of corneal diseases. ... | 02/02/2010 |
| 7645794 | Composition and method for increasing the anabolic state of muscle cells A nutritional supplement comprising at least a therapeutically effective amount of ethyl pyruvate and a therapeutically effective amount of at least one α-hydroxy branched-chain amino acid metabolite is provided by the present invention. The ingredients of the pres... | 01/12/2010 |
| 7642286 | Stable pharmaceutical compositions containing pravastatin Stabilized pharmaceutical preparations containing a drug in which is sensitive to a low pH environment, such as pravastatin are disclosed in which pravastatin degradations is prevented with a buffering agent. The basic excipient enhances storage stability. ... | 01/05/2010 |
| 7642287 | Statin pharmaceutical compositions and related methods of treatment The invention provides novel omega-3 oil solutions of one or more statins. These solutions are readily bioavailable. Notably, because the solutions of the invention contain an omega-3 oil as the major ingredient, they not only provide an antihypercholesterolemic eff... | 01/05/2010 |
| 7629383 | Double esters The invention provides acyloxymethyl esters of C6-14 alkane-dicarboxylic acids, or physiologically tolerable salts or esters thereof, for use in medicine as therapeutic or prophylactic agents. ... | 12/08/2009 |
| 7619001 | Utilization of dialkylfumarates The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For ... | 11/17/2009 |
| 7612110 | Utilization of dialkylfumarates The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune diseases and said compositions in the form of micro-tablets or pellets. For ... | 11/03/2009 |
| 7592370 | Fatty acid treatment for cardiac patients A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mi... | 09/22/2009 |
| 7585896 | Composition for the prevention and treatment of kidney dysfunctions and diseases A composition is disclosed which is suitable for the prevention and treatment of kidney dysfunctions and diseases and which can therefore take the form of a food supplement or of an actual medicinal drug comprising a combination of acetyl L-carnitine and propionyl L... | 09/08/2009 |
| 7416865 | Process for the preparation of dihydroxy esters and derivatives thereof A process is provided for the preparation of a compound of formula (1) wherein R and R′ represent optionally substituted hydrocarbyl groups and X represents a hydrocarbyl linking group. The process comprises either the st... | 08/26/2008 |
| 7378107 | Serum remnant-like lipoprotein concentration regulator The present invention discloses serum remnant-like lipoprotein concentration regulators containing triglyceride of medium-chain fatty acids, wherein 90% or more by weight of the fatty acids as components of the medium-chain triglyceride are saturated fatty acids hav... | 05/27/2008 |
| 7375135 | Fatty acid derivatives; preparation and uses thereof The invention concerns novel molecules, their preparation and their uses, in particular in the field of human and veterinary medicine and cosmetics. The inventive compounds are partly fatty acid derivatives and exhibit advantageous pharmacological and cosmetic prope... | 05/20/2008 |
| 7371889 | Chemical entities with multiple modes of anti-inflammatory action The invention relates to new chemical compounds that inhibit the various enzymes in the arachidonic acid pathway implicated in inflammatory disease conditions. ... | 05/13/2008 |
| 7368125 | Amphiphilic polymers for medical applications The present invention is directed to medical devices or pharmaceutical compositions, each containing a synthetic, bioabsorbable, biocompatible polymer that is the reaction product of a polybasic acid or derivative thereof, a monoglyceride, and a polyether. ... | 05/06/2008 |
| 7361644 | Specific antagonist for both E- and P-selectins Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 04/22/2008 |
| 7326426 | Compositions and medical devices utilizing bioabsorbable liquid polymers The present invention is directed to medical devices and pharmaceutical compositions containing a synthetic, bioabsorbable, biocompatible liquid polymer that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the liquid pol... | 02/05/2008 |
| 7314645 | Process for preparing nutritious cooked rice in aseptic package A process for preparing nutritious cooked rice in an aseptic package, by mixing ginseng, jujube, chestnut and black rice, which has excellent taste and smell and capability of long-term preservation at room temperature. The process includes treating ginseng, jujube ... | 01/01/2008 |
| 7314862 | Antitumor agent The present invention relates to an antitumor agent containing a histone deacetylase inhibitor and a topoisomerase II inhibitor in combination. This combination has been found to exhibit a synergistic anticancer or antitumor effect compared to administration of eith... | 01/01/2008 |
| 7304093 | Ketone compounds and compositions for cholesterol management and related uses The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a com... | 12/04/2007 |
| 7300957 | Skin care compositions Provided are compositions which are suitable for topical application to human skin for cleansing and anti-microbial properties. In one preferred embodiment, the compositions include a glyceryl monoazelate ester. In another embodiment, the compositions include a glyc... | 11/27/2007 |
