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| Number | Title | Issue Date |
| 5882628 | Contrast media The invention provides low viscosity iodinated aryl compounds, useful as X-ray contrast agents, of formula I ##STR1## (wherein n is 0 or 1, and where n is 1 each C6 R5 moeity may be the same or different; each group R is a hydro... | 03/16/1999 |
| 5883123 | Butyrate prodrugs derived from lactic acid This invention relates to butyrate prodrugs derived from lactic acid and pharmaceutical compositions and methods employing them, either alone or in combination with other agents, for increasing gamma globin and fetal hemoglobin in a patient. These compoun... | 03/16/1999 |
| 5876916 | Pyruvate compounds and methods for use thereof The invention comprises a novel pyruvate compound for the treatment or prevention of reperfusion injury following ischemia, diabetic effects, cholesterol levels, injured organs, ethanol intoxication or as a foodstuff. The novel pyruvate compound is partic... | 03/02/1999 |
| 5874469 | Fluoroalkyl hydrocarbons for administering water insoluble or unstable drugs Fluoroalkyl hydrocarbons as vehicles for pharmaceutical drugs are disclosed. These vehicles are particularly well-suited for delivering drugs which are insoluble in water or chemically unstable in aqueous media. Pharmaceutical solution compositions based ... | 02/23/1999 |
| 5874071 | Antiodor, antimicrobial and preservative compositions and methods of using same Therapeutic treatment as well as prophylactic measures are provided by topical application of compositions containing an aryl 2-acetoxyethanoic acid to eradicate or prevent the development of axillary foul odor, foot malodor and other body odors, e.g. sca... | 02/23/1999 |
| 5869338 | Method for protection against genotoxic mutagenesis A method and pharmaceutical for protecting against mutational damage in mammalian cells, irrespective of the nature of the mutagenic event or source of radiational or chemical insult or the like.... | 02/09/1999 |
| 5861435 | Method for preventing settlement of aquatic fouling organisms A method for preventing settlement of aquatic fouling organisms on surface of an aquatic structure without environmental hazard is provided. The method is based upon absolutely novel concept to prevent the settlement by means of thick slime layer, i.e. bi... | 01/19/1999 |
| 5849732 | Phenol compound having antioxidative activity and the process for preparing the same Disclosed are a phenol compound represented by the formula (1): ##STR1## wherein R0 represents H, alkyl or alkyloxy; R1 represents alkyl; R2 represents alkyl or alkyloxy; OR3 represents OH; R4 re... | 12/15/1998 |
| 5849793 | HIV matrix protein tyrosine position 29 pocket binders There is disclosed a structural genus of compounds, defined according to coordinates in three-dimensional space, that binds amino moieties on neighboring lysine residues in a tyrosine residue 29 pocket of the matrix protein component of the HIV preintegra... | 12/15/1998 |
| 5849801 | 4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds 4-amino-5-oxy-2,6,6-tri methyl-2-cycloheptene compounds represented by the following general formula: ##STR1## (wherein R1 and R2 each independently represent a hydrogen atom, an alkyl group which may have a substituent, or a ph... | 12/15/1998 |
| 5847003 | Oxa acids and related compounds for treating skin conditions Described are the use of compounds of Formula (I) depicted below, as active principals for treating skin conditions and compositions containing these compounds, ##STR1## where R4 is (CR5 R6 --CR7 R8 | 12/08/1998 |
| 5840343 | Room temperature sterilant for medical devices Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two parts. One part contains the ester of formic acid and a sec... | 11/24/1998 |
| 5833960 | Foaming light protection preparations containing water-soluble light protection filters and surface-active substances Active substance combinations of (a) one or more surface-active substances selected from the group comprising glucose derivatives, (b) one or more surface-active substances selected from the group comprising glycerol monocarboxylic or dicarboxylic acid monoest... | 11/10/1998 |
| 5834521 | Substituted dibenz (A F)azulenes and methods of preparation Tetracyclic compounds having the following structure are described: ##STR1## wherein R1 -R10 are as defined. The tetracyclic compounds are capable of potent effects on steroid sensitive tissues and have demonstrated increased ut... | 11/10/1998 |
| 5827882 | Method of using ethyl pyruvate for treating wrinkles Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin ethyl pyruvate.... | 10/27/1998 |
| 5827883 | Dermatological use of vitamin D derivatives A method of using vitamin D derivatives of the formula ##STR1## wherein X is .dbd.CH2 or H,H; Y is a moiety --CH(CH3)--(A)n --C(O)--OR1 (a) --CH(CH3)--CH2 --O--C(O)--R2 | 10/27/1998 |
| 5814659 | Topical analgesic composition The present invention comprises a topical analgesic composition comprising an analgesic agent, an alcohol, a chaotropic agent and an unsaturated fatty acid. The composition is preferably in the form of a stable gel and may further comprise a pharmaceutica... | 09/29/1998 |
| 5811129 | Hydroxylated milk glycerides Hydroxylated milk glycerides having low levels of ethylenic unsaturation are disclosed. The hydroxylated milk glycerides can have enhanced resistance to rancidification and as such, are suitable for use in personal care compositions e.g., lotions, skin cr... | 09/22/1998 |
| 5811421 | Naphthyl and dihydronaphthyl intermediates, compounds, compositions, and methods The present invention provides compounds of formula ##STR1## wherein R1 is --H, --OH, --O(C1 -C4 alkyl), --OCOC6 H5, --OCO(C1 -C6 alkyl), or --OSO2 (C4 -C | 09/22/1998 |
| 5811458 | Phenyl propane derivatives as antibiotics and lipoxygenase inhibitors The invention relates to phenyl propane derivatives of the general formulae: ##STR1## or their mixtures, in which R1 and R2 are a branched or straight-chained alkyl residue of the general formula Cn H2n+1 ... | 09/22/1998 |
| 5804549 | Compositions with activity against helicobacter Disclosed are compositions of nisin and GML as active ingredients for the killing of Helicobacter, as well as methods for eradicating Helicobacter colonization and treatment of Helicobacter infection which employ the GML/nisin compositions.... | 09/08/1998 |
| 5798354 | Use of adamantyl-substituted polycyclic acetylene compounds in skin and hair treatment Novel pharmaceutically/cosmetically-active adamantyl-substituted polycyclic acetylene compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(f): ##STR2## and are useful for the treatment of a ... | 08/25/1998 |
| 5786388 | Meadowfoam esters as skin conditioners The present invention deals with the use certain novel esters which are prepared by the reaction of an alcohol and meadowfoam fatty, methyl ester or triglyceride in personal care applications. These materials are useful as cosmetic ingredients where outst... | 07/28/1998 |
| 5786389 | Guerbet castor esters The present invention deals with the certain castor esters which give high gloss when applied to the skin. Said esterd are the reaction of a guerbet alcohol and castor oil, ricinoleic acid or methyl ricinoleate.... | 07/28/1998 |
| 5786366 | Method and apparatus for rehydrating dry skin A method for rehydrating dry skin of an individual is disclosed. In accordance with the method, a balm of lanolin and hydroxyquinoline sulfate is first applied to the skin surface to be treated, wherein the skin surface is a hand or a foot of an individua... | 07/28/1998 |
| 5783600 | Carboxyalkylethers, formulations, and treatment of vascular diseases Dialkyl ethers lower Lp(a) and triglycerides, and elevate HDL-cholesterol, and are thereby useful for treating vascular diseases and noninsulin-dependent diabetes mellitus.... | 07/21/1998 |
| 5776951 | Anti-atherosclerotic diaryl compounds The present invention is concerned with diaryl compounds of formula (l) and their use in medical therapy, particularly in the prophylaxis or treatment of a clinical condition for which an ACAT inhibitor is indicated, such as hyperlipidaema or atherosclero... | 07/07/1998 |
| 5776981 | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals A method of systemically controlling endoparasites and ectoparasites of warm-blooded animals by orally or percutaneously administering to the animal a parasiticidally effective amount of an acyl urea compound.... | 07/07/1998 |
| 5773466 | Pharmaceutical product comprising sympathomimetic drug having therapeutic properties on the human sensibility and autocinesis in general A pharmaceutical product is disclosed which interferes with pathologies of human sensitivity and of the motor system. This product comprises parasympathomimetic drugs, in particular carbachol, methacholine or bethanechol and it has a broad application in ... | 06/30/1998 |
| 5760022 | Pharmaceutical composition with improved bioavailability of inositol phosphate The invention relates to an inositol phosphate containing pharmaceutical composition which comprises an aliphatic ester or ether for improvement of the bioavailability of the inositol phosphate in mammals including man at non-parenteral administration. Th... | 06/02/1998 |
| 5756128 | Agricultural chemical preparations and method for preparing same Disclosed are an agricultural chemical preparation which comprises 100 parts by weight of a fatty acid ester of an aliphatic polyhydric alcohol, 10 to 2000 parts by weight of an agricultural effective component and 10 to 400 parts by weight of a surfactan... | 05/26/1998 |
| 5756544 | Carboxyalkylethers, formulations, and treatment of vascular diseases Dialkyl ethers lower Lp(a) and triglycerides, and elevate HDL-cholesterol, and are thereby useful for treating vascular diseases and noninsulin-dependent diabetes mellitus.... | 05/26/1998 |
| 5753611 | Pharmaceutical composition having site-specific delivery Use of -hydroxy acids and poly--hydroxy acids as spacer between a therapeutically and/or diagnostically active compound and a soluble macromolecular carrier in pharmaceutical compositions having site-specific delivery. In one embodiment glyc... | 05/19/1998 |
| 5750569 | Carboxyalkylethers, formulations, and treatment of vascular diseases Dialkyl ethers lower Lp(a) and triglycerides, and elevate HDL-cholesterol, and are thereby useful for treating vascular diseases and noninsulin-dependent diabetes mellitus.... | 05/12/1998 |
| 5750091 | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof A method for inducing melanin synthesis in melanocytes, thereby increasing the melanin content of melanocytes and, thus, increasing pigmentation, melanocytes with increased melanin content produced by these methods, and uses thereof.... | 05/12/1998 |
| 5750571 | Methods and therapeutic compositions for treating cystic fibrosis Methods for treating cystic fibrosis are described. The methods involve the administration of a protein enhancing agent, differentiating agent and/or carboxy-compound to a subject afflicted with cystic fibrosis such that mutant cystic fibrosis transmembra... | 05/12/1998 |
| 5736571 | Guerbet meadowfoam esters in personal care The present invention deals with the application of certain novel esters which are prepared by the reaction of a guerbet alcohol and meadowfoam fatty, methyl ester or triglyceride in personal care applications. These materials are useful as cosmetic ingre... | 04/07/1998 |
| 5731349 | Medicinal preparation of antistress, stess-protective and nootropic effect A pharmaceutical preparation of antistress, stress-protective and nootropic effect contains an effective substance represented by an amino-acid glycine or its pharmaceutically acceptable salt. A method of prophylaxis and curing of stress states and also increa... | 03/24/1998 |
| 5728739 | Stimulating the differentiation of preadipocytic cells and therapies based thereon The differentiation of preadipocytic cells into adipocytic cells, in particular for correcting insulin-resistance disease states in mammalian organisms, notably in humans, for example type II diabetes and cardiovascular disorders such as hypertension and ... | 03/17/1998 |
| 5728732 | Skin treatment with salicylic acid esters and retinoids A method and composition is provided for treating skin conditions including those arising from dermatologic disorders, chronoaging and environmental abuse. Non-ring esterified C11 -C30 alkyl or alkenyl esters of salicylic acid in com... | 03/17/1998 |
