Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
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| Number | Title | Issue Date |
| 8101660 | Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of skin cancer The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, skin cancer. ... | 01/24/2012 |
| 8053471 | Nutrition containing fat blend The invention relates to the use of long chain polyunsaturated fatty acids for the manufacture of a nutritional composition for feeding infants of a mother who suffered from a metabolic disorder during pregnancy and to a corresponding composition. Said composition c... | 11/08/2011 |
| 8048918 | Treatment of hyperproliferative diseases We describe methods and compositions for treating a patient suffering from a hyperproliferative disorder or photoageing. Our methods involve blocking the activity of a retinol binding protein receptor (RBPr) in cells of the patient, and/or administering to the patie... | 11/01/2011 |
| 8048919 | Use of ethyl lactate as an excipient for pharmaceutical compositions This invention is based upon the unexpected discovery that ethyl lactate can be used as an emulsifying/dispersing excipient for numerous biologically active compounds without destroying the pharmacological activity of the active ingredient. Ethyl lactate proves to b... | 11/01/2011 |
| 8048920 | Personal care composition containing bio-derived 1,3-propanediol and its conjugate esters Biodegradable personal care compositions comprising 1,3-propanediol are provided, and the 1,3-propanediol in the composition is biologically derived. The compositions exhibit a lower anthropogenic CO2 emission profile. Also provided are biodegradable pers... | 11/01/2011 |
| 7923471 | Method of treating dry eye disorders and uveitis The topical use of 5,6,7-trihydroxyheptanoic acid and analogs are disclosed for the treatment of dry eye disorders and uveitis. ... | 04/12/2011 |
| 7897640 | Method of treatment of virus infections using shikonin compounds Medicaments containing shikonin compounds and salts thereof including shikonin and alkannin are used for treatment of virus infections, mycoplasma infections and malignant tumor. ... | 03/01/2011 |
| 7863328 | Phenylbenzoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and therapeutic uses thereof Compounds of the formula (1) in which R1, R2, X, Y and Z are as defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmac... | 01/04/2011 |
| 7851505 | Thiotungstate analogues and uses thereof The current invention provides novel thiotungstate derivatives, methods of making novel thiotungstate derivatives, pharmaceutical compositions of novel thiotungstate derivatives, methods of using novel thiotungstate derivatives to treat diseases associated with aber... | 12/14/2010 |
| 7834056 | Pharmaceutical composition for gout A composition for hyperuricemia disease or a related disorder, use thereof and method of using thereof are provided. ... | 11/16/2010 |
| 7807715 | Pharmaceutical compositions comprising fesoterodine The present application relates to a pharmaceutical granulate comprising Fesoterodine or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable stabilizer, which can be selected from the group consisting of sorbitol, xylitol, polydex... | 10/05/2010 |
| 7795308 | Composition and/or method for preventing recurrence of stroke By using a composition for preventing onset and/or recurrence of stroke which contains ethyl icosapentate as its effective component, onset and/or recurrence of stroke is prevented, or in particular, the onset and/or recurrence of stroke in a hyperlipidemia patient ... | 09/14/2010 |
| 7759393 | Bio-derived 1,3-propanediol and its conjugate esters as natural and non irritating solvents for biomass-derived extracts, fragrance concentrates, and oils Compositions containing 1,3-propanediol and an extraction product are provided, and the 1,3-propanediol in the composition is biologically derived. Also provided are processes for extracting an extract from a source. These processes include providing an ester of 1,3... | 07/20/2010 |
| 7754764 | Fatty acid nutritional supplement A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can... | 07/13/2010 |
| 7732488 | Pharmaceutical composition comprising low concentrations of environmental pollutants The invention relates to a process for decreasing the amount of environmental pollutants in a mixture comprising a fat or an oil, being edible or for use in cosmetics, the fat or oil containing the environmental pollutants, which process comprises the steps of addin... | 06/08/2010 |
| 7705048 | Method of suppressing the effects of the translocase deficiency of a human infant comprising administration of a seven-carbon fatty acid A seven-carbon fatty acid or derivative thereof has been identified as an excellent energy source for humans or human infants. A nutritional supplement suitable for humans or human infants comprising a seven carbon fatty acid chain compound or derivative thereof can... | 04/27/2010 |
| 7662852 | Compounds and preparations having antiviral effect An antiviral preparation comprising as an active ingredient, a phorbol derivative of formula 1: wherein is R1 is —(CH2)aX(CH2)bCH3, —(CH2) | 02/16/2010 |
| 7659310 | Methods of enhancing solubility of agents This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions. ... | 02/09/2010 |
| 7608639 | Phenoxyether derivatives as PPAR modulators The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR), such... | 10/27/2009 |
| 7560485 | Method for treating intermittent claudication comprising the administration of propionyl L-carnitine and a concomitant physical training The present invention discloses a method for treating a subject suffering from intermittent claudication (IC) wherein said subject takes an effective dose of propionyl L-carnitine or a pharmaceutically acceptable salt thereof and also engaging in a concomitant physi... | 07/14/2009 |
| 7438923 | Synergistic and residual pesticidal compositions containing plant essential oils with enzyme inhibitors Synergistic and residual pesticidal compositions containing synergistic and residual mixtures of plant essential oils in admixture with enzyme inhibitors, with or without other compounds not previously used as active ingredients in pesticidal formulations. In additi... | 10/21/2008 |
| 7419998 | Therapeutic methods and compositions involving isoflavones Therapeutic methods of treatment, compositions and foodstuffs are described which contain isoflavone compounds described by general formula (I), in which Z is H, R1 is H, or RACO where RA is C1-10alkyl or an amino acid, R | 09/02/2008 |
| 7414077 | Therapeutic intervention to mimic the effect of caloric restriction Methods are provided for promoting longevity and decreasing the incidence of ageing associated pathologies (e.g. cancer) by the administration of one or more of the following LFFA: linoleic, oleic, and palmitic acid. Secondary LFFA derived from this set, as well as ... | 08/19/2008 |
| 7414075 | Composition for lowering internal lipid content A composition for lowering internal lipid in a subject which contains a capsinoid substance represented by the following formula wherein n is an integer from 0 to 10. Methods of using the compositions are disclosed and incl... | 08/19/2008 |
| 7405239 | Acylhydrazone derivatives and the use thereof in the inhibition, regulation and/or modulation of kinase signal transduction The invention relates to acylhydrazone derivatives of formula (I), which are SGK inhibitors and can be used for the treatment of diseases and afflictions associated with SGK, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systematic and pulmonary hyp... | 07/29/2008 |
| 7381731 | Pharmaceutical composition comprising citrulline Embodiments of the present invention include compositions and pharmaceutical compositions comprising citrulline and Hmg-CoA reductase inhibitors. Further embodiments relate to the use of such composition treat subjects and stimulating nitric oxide synthase. ... | 06/03/2008 |
| 7381416 | Selenohydroxy acids and their derivatives, applications in nutrition, cosmetics and pharmaceutics The purpose of this invention is: new selenohydroxy acid compounds and their derivatives; their process for the preparation; use of the new compounds as precursors of L(+)-selenomethionine and/or s... | 06/03/2008 |
| 7361664 | Vitamin D receptor antagonists and related compositions and methods of use A compound of formula: wherein X is a C2-10 spacer, and R is a substituted or unsubstituted C6-30 aryl, a substituted or unsubstituted C5-30 heteroaryl, or ... | 04/22/2008 |
| 7357939 | Synergistic and residual pesticidal compositions containing plant essential oils with enzyme inhibitors Synergistic and residual pesticidal compositions containing synergistic and residual mixtures of plant essential oils in admixture with enzyme inhibitors, with or without other compounds not previously used as active ingredients in pesticidal formulations. In additi... | 04/15/2008 |
| RE40246 | Method for the suppression of viral growth A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula: wherein R1, R2, R3 and R4 are indep... | 04/15/2008 |
| 7351719 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds The present invention relates to amide compounds of general formula I wherein the groups and residues A, B, b, W, X, Y, Z, R1, R2 and R3 have the meanings given in claim 1. Moreover t... | 04/01/2008 |
| 7348023 | Absorbent articles containing additives Absorbent articles containing an additive are disclosed. The absorbent articles include an effective amount of an inhibitory compound, such as thiolactomycin or thiomalonate, to substantially inhibit the production of TSST-1 by Gram positive bacteria. ... | 03/25/2008 |
| 7348315 | Methods of treating heart failure with modified ATP, ADP and AMP compounds Disclosed herein are methods of using an adenosine analog or derivative for treating heart failure, increasing cardiac muscle contractility, increasing cardiac diastolic relaxation, and increasing vasodilation. Exemplary adenosine analogs/derivatives include compoun... | 03/25/2008 |
| 7323186 | Non-absorbent articles containing additives Non-absorbent articles, such as tampon applicators, containing an additive are disclosed. The non-absorbent articles include an effective amount of an inhibitory compound, such as thiolactomycin or thiomalonate, for example, to substantially inhibit the production o... | 01/29/2008 |
| 7314624 | Nanoemulsion vaccines The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental... | 01/01/2008 |
| 7297817 | Thio-substituted arylmethanesulfinyl derivatives The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): wherein ... | 11/20/2007 |
| 7294739 | Basic amine esters or oleic acid and their use as anti-inflammatory or immunobodulatory agents This invention is directed to compounds of the following formula (I): wherein R is either: | 11/13/2007 |
| 7291646 | Ethers of O-desmethyl venlafaxine This invention provides O-α-acyloxyalkyl ethers of the venlafaxine metabolite 4-[2-(Dimehtylamino-1-(1-hydroxycyclohexyl)ethyl]phenol, represented by Formula (I): wherein the variables R1 and R2 ... | 11/06/2007 |
| 7288525 | Method for lowering serum homocysteine The present invention provides a method for reducing the amount of homocysteine in the blood of an individual. The method comprises administering to the individual a composition comprising a homocysteine lowering agent in an amount effective to lower the amount of h... | 10/30/2007 |
| 7268160 | Remedies The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor producti... | 09/11/2007 |
