Quotables
"Radio has no future."
Lord Kelvin, British mathematician and physicist ; 1897
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8404744 | Methods of treatment and pharmaceutical composition The invention relates a pharmaceutical composition comprising a combination of (i) the AT 1-antagonist valsartan or a pharmaceutically acceptable salt thereof and (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and optionally a pharmaceutically ac... | 03/26/2013 |
| 8394853 | Substituted aminopropionic derivatives as neprilysin inhibitors The present invention provides a compound of formula I′; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined herein. The in... | 03/12/2013 |
| 8377986 | Amino acid derivatives The compound 3,3-dimethyl-butyric acid 4-((S)-2-amino-2-methoxycarbonyl-ethyl)-2-(3,3-dimethyl-butyryloxy)-phenyl ester of formula (I) has dopaminergic properties. ... | 02/19/2013 |
| 8324272 | Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use Levodopa dimethyl-substituted diester prodrugs pharmaceutical, compositions comprising levodopa dimethyl-substituted diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided. | 12/04/2012 |
| 8324273 | Catechol protected levodopa diester prodrugs, compositions, and methods of use Catechol protected levodopa diester prodrugs pharmaceutical, compositions comprising catechol protected levodopa diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided. ... | 12/04/2012 |
| 8299119 | Biologically active compounds Compounds having useful biological activity, particularly antioxidant and anti-inflammatory activity, derived from Centipeda cunninghamii, and biologically active derivatives thereof, pharmaceutical compositions comprising these compounds, and prophylactic an... | 10/30/2012 |
| 8268884 | Derivatives of substituted tartaric acid and usage for preparing beta-secretase inhibitors The present invention relates to compounds represented by formula (I), or isomers, prodrugs, pharmaceutically acceptable salts, solvates or hydrates thereof: in which each substituent of formula (I) is as defined in the spe... | 09/18/2012 |
| 8101659 | Methods of treatment and pharmaceutical composition The invention relates a pharmaceutical composition comprising a combination of: (i) the AT 1-antagonist valsartan or a pharmaceutically acceptable salt thereof; and (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and opti... | 01/24/2012 |
| 7943665 | Anticancer agents based on regulation of protein prenylation Oncoproteins such as Ras and RhoB are known to induce cell division in an unrestrained manner when such proteins are localized at the inner surface of a cancer cell membrane. The localization is effected by the prenylation reaction, whereby a hydrophobic group (e.g.... | 05/17/2011 |
| 7829592 | Catechol protected levodopa diester prodrugs, compositions, and methods of use Catechol protected levodopa diester prodrugs pharmaceutical, compositions comprising catechol protected levodopa diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided. ... | 11/09/2010 |
| 7807714 | Fungicidal compositions A composition suitable for control of diseases caused by phytopathogens comprising (A) a compound of formula (I) or a tautomer of such a compound; and component (B) and component (C) are pesticides as described in claim 1. | 10/05/2010 |
| 7799830 | Cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease The present invention relates to cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease, which have excellent effect on enhancing the learning and memory-retention ability in vivo and have fewer side-effects by showing no ... | 09/21/2010 |
| 7799831 | Lipophilic diesters of chelating agent for inhibition of enzyme activity The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases and of calpain. The invention further r... | 09/21/2010 |
| 7709527 | Levodopa dimethyl-substituted diester prodrugs compositions, and methods of use Levodopa dimethyl-substituted diester prodrugs pharmaceutical, compositions comprising levodopa dimethyl-substituted diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided. | 05/04/2010 |
| 7666906 | β-Benzyloxyaspartate derivatives with amino group on benzene ring L-threo-β-benzyloxyaspartate derivatives having a substituent on the benzene ring, represented by the following formula (1): wherein R is hydrogen, a linear or branched lower aliphatic acyl group with the acyl portion opti... | 02/23/2010 |
| 7592369 | Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use Acyloxyalkyl carbamate prodrugs of trans-4-(aminomethyl)-cyclohexanecarboxylic acid, pharmaceutical compositions thereof, methods of making prodrugs of trans-4-(aminomethyl)-cyclohexane-carboxylic acid, and methods of using prodrugs of trans-4-(aminomethyl)-cyclohex... | 09/22/2009 |
| 7589123 | Chemical compounds Compounds of general formula I: wherein: R1 and R2 are, independently of each other, selected from hydrogen, optionally substituted C1-10alkyl, optionally substituted —CO—(C... | 09/15/2009 |
| 7572830 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analog... | 08/11/2009 |
| 7507764 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes Herein are disclosed substituted fullerenes, comprising a fullerene core (Cn), wherein n is an even integer greater than or equal to 60; 3 or 5 dihydrocarbylmalonate (>C(COOR1)(COOR2)) groups bonded to the fullerene core; and 1 or 3 polar exten... | 03/24/2009 |
| 7468390 | Methods of treatment and pharmaceutical composition The invention relates a pharmaceutical composition comprising a combination of: (i) the AT 1-antagonist valsartan or a pharmaceutically acceptable salt thereof; and (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and opti... | 12/23/2008 |
| 7423170 | Anticancer agents based on regulation of protein prenylation Oncoproteins such as Ras and RhoB are known to induce cell division in an unrestrained manner when such proteins are localized at the inner surface of a cancer cell membrane. The localization is effected by the prenylation reaction, whereby a hydrophobic group (e.g.... | 09/09/2008 |
| 7390821 | Methods of reducing angiogenesis The present invention provides methods of reducing angiogenesis in an individual. The methods generally involve administering to the individual an effective amount of a nicotinic acetyl choline receptor antagonist. The methods are useful to treat conditions associat... | 06/24/2008 |
| 7384979 | Substituted amino acids as erythropoietin mimetics This invention relates to a series of substitituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which ... | 06/10/2008 |
| 7381745 | Ligands for metabotropic glutamate receptors and inhibitors of NAALADase The present invention relates to novel compounds and formulations thereof which compounds are ligands, e.g., agonists or antagonists, for a metabotropic glutamate receptor or a NAALADase enzyme or both. The present invention also relates to methods of modulating the... | 06/03/2008 |
| 7368249 | Methods and compositions for evaluation and modulation of fertility The present invention concerns compositions and methods for regulating or determining fertility in humans and animals. In various embodiments of the invention, LOX and other related enzymes can be used as fertility markers, contraceptive agents, or means of treating... | 05/06/2008 |
| 7368123 | Pesticidal resin compositions and pesticidal products formed from the same According to the present invention, there is provided a pesticidal resin composition that contains (A) at least one resin selected from polyamide resins and polyacetal resins, (B) at least one compound selected from sulfone amide derivatives, sulfonic acid ester der... | 05/06/2008 |
| 7351740 | Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use Acyloxyalkyl carbamate prodrugs of trans-4-(aminomethyl)-cyclohexanecarboxylic acid, pharmaceutical compositions thereof, methods of making prodrugs of trans-4-(aminomethyl) -cyclohexane-carboxylic acid, and methods of using prodrugs of trans-4-(aminomethyl) -cycloh... | 04/01/2008 |
| 7342127 | Substituted anilide ligands for the thyroid receptor Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7,... | 03/11/2008 |
| 7342044 | Preservative blends containing quaternary ammonium compounds The present invention provides a biocidal composition comprising a synergistic mixture of certain quaternary ammonium biocides and one or more ketone acids, aromatic carboxylic acids, salts thereof, or mixtures thereof. ... | 03/11/2008 |
| 7342131 | Levodopa prodrugs, and compositions and uses thereof Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed. ... | 03/11/2008 |
| 7332505 | Nitrosated and nitrosylated proton pump inhibitors, compositions and methods of use The present invention describes novel nitrosated and/or nitrosylated proton pump inhibitor compounds, and novel compositions comprising at least one proton pump inhibitor compound that is optionally substituted with at least one NO and/or NO2 group, and, ... | 02/19/2008 |
| 7312245 | Diamine derivatives, process for producing the diamine derivatives, and fungicides containing the diamine derivatives as an active ingredient A fungicide can be provided by using, as an active ingredient, a diamine derivative of the following general formula (1): wherein R1 to R7 represent a specific substituen... | 12/25/2007 |
| 7312246 | Proteomimetic compounds and methods The present invention relates to compounds and pharmaceutical compositions which are proteonaimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are ... | 12/25/2007 |
| 7300956 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, methods of making prodrugs of (±)-4-amino-3-(4-chlorophenyl)butanoic acid and analog... | 11/27/2007 |
| 7288573 | Method of repelling insects A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 ... | 10/30/2007 |
| 7288622 | Composition for treatment of burns and wounds A composition is provided to heal burns, wounds and other skin traumas of mammals. The composition is useful to treat sepsis and to improve skin formation as well. The composition comprises an antimicrobial peptide having amino acid sequence FAKKFAKKFKKFAKKFAKFAFAF.... | 10/30/2007 |
| 7288271 | Chlorogenic acid and an analog thereof for immune system stimulation The present invention relates to a preparation for stimulating or enhancing an immune system comprising one or more agents that stimulate T-lymphocytes in vivo. Such a preparation can be sued in the prophylaxis and/or treatment of a medical condition. The invention ... | 10/30/2007 |
| 7279582 | Retroviral protease inhibiting compounds A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed. ... | 10/09/2007 |
| 7262219 | Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to the conversion into GBL. Disclosed are methods to treat sleep disorde... | 08/28/2007 |
| 7253169 | Aza compounds, pharmaceutical compositions and methods of use The present invention relates to N-substituted cyclic aza compounds, pharmaceutical compositions comprising such compounds, and methods of their use for effecting neuronal activities. ... | 08/07/2007 |
