Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 5616567 | 2'-Cyano pyrimidine nucleoside compounds The pyrimidine compounds of the present invention are represented by the following formula: ##STR1## and pharmaceutically acceptable salts thereof, wherein, R1 represents a hydroxyl or an amino which may be substituted by an acyl group; R | 04/01/1997 |
| 5614505 | Method of treating cancer with homo-oligonuleotides of 5-FU 5'-monophosphate Homo-oligomeric 5-fluorouridine and 5-fluorodeoxyuridine (FrUn and FdUn, n=oligomer length) are synthesized and used as a polymeric drug delivery system for production of FdUMP, the potent inhibitor of thymidylate synthase (TS) and a... | 03/25/1997 |
| 5612060 | Enhancement of transplant graft survival through nutritional immunomodulation and immunosuppressive therapy An improved immunomodulatory therapy for enhancement of depressed host defense mechanisms as shown by improved allograft survival rates is disclosed. The therapy comprises the synergistic combination of an immunomodulatory diet consisting of an amino acid... | 03/18/1997 |
| 5607925 | Treatment of carcinoma by administration of 2'-halomethylidenyl-2'-deoxynucleosides This invention relates to certain novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease stat... | 03/04/1997 |
| 5604209 | Synergistic antiviral compositions Antiviral agents which comprises as active ingredients one or more 2',3'-dideoxyribonucleosides or phosphoric esters thereof and 6-benzyl-1-ethoxymethyl-5-substituted uracil derivative of the formula (I): ##STR1## wherein X is oxygen or sulfur a... | 02/18/1997 |
| 5591722 | 2'-deoxy-4'-thioribonucleosides and their antiviral activity 2'-Deoxy-4'-thio-ribonucleosides, intermediates in their production, and their use as antiviral and anticancer agents are disclosed.... | 01/07/1997 |
| 5587362 | L-nucleosides A compound, and a pharmaceutical composition comprising an effective mount to treat HBV or EBV of a compound, of the formula: ##STR1## wherein R is selected from the group consisting of 5-methyluracil, adenine and cytosine, and R' is hydrogen, acyl, ... | 12/24/1996 |
| 5585363 | Circumvention of human tumor drug resistance A method involving the administration of nucleoside analogs to circumvent resistance attributable to the enhanced DNA repair capacity of cancer cells is described. The nucleoside analogs function as suicide substrates for DNA repair enzymes. A method of s... | 12/17/1996 |
| 5583117 | Acylated uridine and cytidine for elevating tissue uridine and cytidine General methods for delivering exogenous cytidine or uridine to the tissue of an animal comprising the administration of acylated cytidine or acylated uridine, respectively, are disclosed. Methods of treating myocardial infarction and cardiac insufficienc... | 12/10/1996 |
| 5578590 | Pharmaceutical composition preparation for use in inhibiting protein kinase C The present invention provides a method of inhibiting protein kinase C in a mammal having a tumor system which contains protein kinase C, which mammal is undergoing cytostatic therapy. The method comprises administering to the mammal a protein kinase C in... | 11/26/1996 |
| 5574021 | Methods of treatment using 2',3'-dideoxy-2',2'-difluoronucleosides 2',3'-Dideoxy-2',2'-difluoronucleosides are useful for treating susceptible neoplasms and viral infections in mammals.... | 11/12/1996 |
| 5571800 | Method for inhibiting allograft rejection by the administration of 6-azauridine or its triacetate derivative A method for suppressing the rejection of an allograft comprising administering azaribine at a time when the recipient of the allograft begins to mount a reject reaction against the allograft.... | 11/05/1996 |
| 5571798 | Synergistic antiviral nucleoside combinations An antiviral composition comprising in combination an effective antiviral amount of 3'-fluoro-2',3'-dideoxy nucleoside compound I of the formula ##STR1## wherein B is adenine, thymine, guanine, cytosine, inosine, uracil, 5-ethyluracil, 2,6-diaminopur... | 11/05/1996 |
| 5567689 | Methods for increasing uridine levels with L-nucleosides A method of increasing intracellular and plasma uridine levels comprising the coadministration or sequential administration of a compound from at least two of the following groups: 1) uridine phosphorylase inhibitors, uridine, cytidine, prodrugs of uridin... | 10/22/1996 |
| 5567688 | L-nucleosides for the treatment of hepatitis B-virus A method for the treatment of a human infected with HBV that includes administering an HBV-treatment amount of an L-nucleoside of the formula: ##STR1## wherein R is selected from the group consisting of 5-methyluracil, adenine and cytosine, and R' is... | 10/22/1996 |
| 5565438 | L-nucleosides for the treatment of epstein-bar virus A method for the treatment of a human infected with EBV that includes administering an EBV-treatment amount of an L-nucleoside of the formula: ##STR1## wherein R is 5-methyluracil, and R' is hydrogen, acyl, alkyl or a monophosphate, diphosphate or tr... | 10/15/1996 |
| 5559101 | L-ribofuranosyl nucleosides This invention relates to and ଲ L-ribofuranosyl nucleosides, processes for their preparation, pharmaceutical compositions containing them, and methods of using them to treat various diseases in mammals.... | 09/24/1996 |
| 5552440 | Use of L-canavanine as a chemotherapeutic agent for the treatment of pancreatic cancer A pharmaceutical composition of canavanine, and a method treatment of cancer, particularly pancreatic cancer with L-canavanine is disclosed.... | 09/03/1996 |
| 5545629 | 5-ethoxy-2'-deoxyuridines A composition comprising 5-ethoxy-2'-deoxyuridine is disclosed which is useful as an antiviral agent.... | 08/13/1996 |
| 5543401 | UDPG as a rescue agent in cancer therapy after the administration of antipyrimidine or related anti-tumor agents with or without BAU A method of rescuing healthy cells of a cancer patient being treated with antipyrimidine antitumor compounds, or related compounds. Rescue is accomplished by administering UDPG after administering the antipyrimidine antitumor compound preferably with BAU ... | 08/06/1996 |
| 5538975 | 1,3-oxathiolane nucleoside compounds and compositions The invention relates to 1,3-oxathiolane nucleoside analogues and their use in the treatment of viral infections. More specifically, this invention relates to (-)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidi n-2-one and pharm... | 07/23/1996 |
| 5527799 | HIV protease inhibitors useful for the treatment of AIDS Compounds of formula ##STR1## where R1 and R2 are independently hydrogen or optionally-substituted C1-4 alkyl or aryl, or R1 and R2 are joined together to form a monocyclic or bicyclic ring syste... | 06/18/1996 |
| 5521163 | Antiviral pyrimidine nucleosides and methods for using same 1'-Deoxy-5-ethyl-4'-thio-ଲ-uridine as a compound including its physiologically functional derivatives, pharmaceutical compositions containing it and methods of treating herpes virus infections are described.... | 05/28/1996 |
| 5506215 | 1-(3'-fluoro-2',3'-dideoxy-ଲ-D-ribofuranosyl)-5-substituted pyrimidine nucleosides A 2',3'-deoxy-3'-fluoro-pyrimidine nucleoside having the formula: ##STR1## wherein R1 is OH or NH2 ; R2 is CF3, CH2 CH2 CH3, ##STR2## CH2 OCH3, CH | 04/09/1996 |
| 5496810 | Pyrimidine deoxyribonucleoside potentiation of combination therapy based on 5-fluorouracil and interferon The applicants have discovered a method of treating malignancies which comprises administering effective amounts of 5-fluorouracil, interferon- and a compound formula (I): ##STR1## wherein R is selected is selected from the group consisting of... | 03/05/1996 |
| 5494900 | UDPG as a rescue agent in cancer therapy after the administration of antipyrimidine or related anti-tumor agents with or without BAU A method of rescuing healthy cells of a cancer patient being treated with antipyrimidine antitumor compounds, or related compounds. Rescue is accomplished by administering UDPG after administering the antipyrimidine antitumor compound preferably with BAU ... | 02/27/1996 |
| 5492899 | Infant nutritional formula with ribo-nucleotides An improved enteral nutritional formula containing ribo-nucleotide equivalents (RNA, mono-, di- and triphosphate nucleotides, nucleosides and adjuncts such as activated sugars) at a level of at least 10 mg/100 Kcal (kilocalorie) of formula is disclosed. T... | 02/20/1996 |
| 5484809 | Prodrugs for oral administration containing taxol or substituted taxol covalently bound to a phospholipid The oral delivery of many classes of drugs is facilitated by converting drugs having suitable functional groups to 1-O-alkyl-, 1-O-acyl-, 1-S-acyl, and 1-S-alkyl-sn-glycero-3-phosphate derivatives. The method confers the ability to be absorbed through the... | 01/16/1996 |
| 5470838 | Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine Methods of delivering exogenous uridine or cytidine to the tissue of an animal comprising the administration of acyl derivatives of uridine or cytidine, respectively, are disclosed. Also disclosed are methods for treating cardiac insufficiency, myocardial... | 11/28/1995 |
| 5466679 | Carboranyl uridines and their use in boron neutron capture therapy The invention relates to novel boron-containing nucleosides and amino acids which can utilize the enzymatic systems in tumor cells for incorporating such boron-containing structures into nucleic acids and proteins. Subsequent use of boron neutron capture ... | 11/14/1995 |
| 5464826 | Method of treating tumors in mammals with 2',2'-difluoronucleosides A method of treating susceptible neoplasms in mammals comprising administering to a mammal in need of such treatment a pharmaceutically effective amount of a compound of the formula ##STR1## wherein: R1 is hydrogen; R2 is a base... | 11/07/1995 |
| 5455234 | Inhibition of hair growth Mammalian hair growth is reduced by applying to the skin an inhibitor of a cysteine synthetic pathway enzyme.... | 10/03/1995 |
| 5449664 | Antiviral agents Nucleoside compounds of the formula ##STR1## wherein: B is a purine or a pyrimidine; X and X' are H, OH or F, provided that at least one is H; Y and Y' are H, OH, OCH3 or F, provided that at least one is H; Y' and Z together form a cyclic phosphate ... | 09/12/1995 |
| 5446029 | Anti-retroviral activity of 2',3'-dideoxy-3'-fluoronucleosides Use of a compound of the formula ##STR1## wherein Base is thymine, Cytosine, adenine or guanine, or a physiologically acceptable salt thereof, for therapeutic treatment of hepatitis B virus infections and to a method for such treatment.... | 08/29/1995 |
| 5446031 | 1-ଲ-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivatives The present invention relates to a novel 1-ଲ-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivative represented by the following formula (I), whose concentration in blood as XVAU can be kept high for many hours when it is administered orally. T... | 08/29/1995 |
| 5432165 | Methods for the treatment of infection caused by Hepatitis B virus (HBV) The present invention relates to pharmaceutical compositions useful for the treatment of subjects suffering from an infection or disease caused by the hepatitis B virus (HBV). In particular, it has been discovered that the administration of low dosage amo... | 07/11/1995 |
| 5432166 | Use of 1-(ଲ-D-arabinofuranosyl) -5-propynyluracil for lowering serum cholesterol The use of 1-(ଲ-D-arabinofuranosyl)-5-propynyluracil or a pharmaceutically acceptable salt or physiologically labile ester thereof for lowering serum cholesterol, particularly low density lipoprotein cholesterol levels in a human subject.... | 07/11/1995 |
| 5430026 | 2'-deoxy-2',2'-difluoro (4-substituted pyrimidine) nucleosides, bicyclic derivatives,pharmaceutical compositions, and synthetic precursors The invention provides certain 2-Deoxy-2,2-Difluoro (4-Substituted) Pyrimidine Nucleosides that are effective as anti-cancer agents and in treating viral infections.... | 07/04/1995 |
| 5430045 | Method of reducing or preventing bone marrow hypoplasia The present invention provides a method for reducing, or preventing, bone marrow hypoplasia in a patient at risk of, or having, same. To this end, when a glutathione intracellular stimulator is administered to such a patient, the risk of bone marrow hypop... | 07/04/1995 |
| 5422343 | Prophylactic and therapeutic composition for MRSA infection The invention provides an anti-MRSA prophylactic/therapeutic composition containing as an active ingredient at least one nucleic acid component selected from among inosine, guanosine n'-monophosphate (GMP) (n'=2', 3'or 5'), uridine and thymidine.... | 06/06/1995 |
