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| Number | Title | Issue Date |
| 4243671 | Inhibition of thromboxane synthetase formation and arachidonic acid-induced platelet aggregation and bronchoconstriction 1-(3-Phenyl-2-propenyl)-1H-imidazole, and its hydrochloride salt have been found to be potent inhibitor of thromboxane synthetase and therefore an inhibitor of arachidonic acid-induced platelet aggregation and bronchoconstriction.... | 01/06/1981 |
| 4239759 | Morpholino containing compounds, compositions and use thereof Compounds of the formula wherein R is a 4-biphenylyl or 4-phenoxyphenyl or a corresponding group monosubstituted or polysubstituted by one or more of F, Cl, and Br; A is --CH(CH3)--CH2 --(CH2)n --, --C(CH3 | 12/16/1980 |
| 4238498 | Antimycotic substituted diphenyl-imidazolyl-methanes The invention provides a series of substituted diphenyl-imidazolyl-methanes useful as antimycotic agents. Also included in the invention are pharmaceutical compositions containing said diphenyl-imidazolyl-methanes and methods for the use of said compounds... | 12/09/1980 |
| 4237158 | 1-Substituted aralkyl imidazoles and their use as fungicides This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in particular are useful as systemic protectant/eradicant fungici... | 12/02/1980 |
| 4230717 | Indomethacin-antihistamine combination for gastric ulceration control An anti-inflammatory and analgesic composition containing indomethacin and an H2 histamine receptor antagonist in an amount sufficient to reduce gastric distress caused by the indomethacin. Usable antagonists are metiamide and cimetidine.... | 10/28/1980 |
| 4213990 | 1,1-Diphenylethene derivatives as microbicides Diphenylethene derivatives of the formula I given herein are new, very valuable microbicides. They can be used on their own or in the form of pesticidal compositions for combating or preventing attack by phytopathogenic fungi, such as mildew and scab dise... | 07/22/1980 |
| 4211782 | Pharmaceutical combination Combinations comprising an anti-aggregatory substance together with one or more of an anti-oxidant and a thromboxane A2 synthetase inhibitor are disclosed. Combinations are useful for the treatment/prophylaxis of disorders attributable to blood... | 07/08/1980 |
| 4200649 | Relieving hypertension with carboxyalkylacylamino acids New carboxyalkylacylamino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.... | 04/29/1980 |
| 4194001 | Synergistic insecticidal compositions Synergized insecticidal and acaricidal compositions comprise a compound of Formula I wherein Y is H or CN, Z is phenyl, or 2,2-dichlorovinyl and R is (i) a group of Formula II where X is Cl or Br, or (ii) a group of Formula III where Q is CH3 o... | 03/18/1980 |
| 4183940 | Antimycotic imidazolyl-9,10-dihydro-anthracene derivatives The invention provides new azolyl-9,10-dihydroanthracene derivatives of the formula ##STR1## in which A represents a CH group or a nitrogen atom, B represents a CO group or a group of the formula: ##STR2## X, Y and Z are identical or different a... | 01/15/1980 |
| 4183742 | 4,5-Dichloro-imidazole-1-carboxylic acid aryl esters and their use as plant protection agents A 4,5-dichloro-imidazole-1-carboxylic acid aryl ester of the formula ##STR1## in which X represents trifluoromethyl, cyano or a group ##STR2## in which R1 represents an optionally substituted saturated or unsaturated aliphatic radical... | 01/15/1980 |
| 4178166 | 4,5-Dichloro-imidazole derivatives and their use as plant protection agents A 4,5-dichloro-imidazole derivative of the formula ##STR1## in which X represents trifluoromethyl, cyano or a ##STR2## in which R1 represents an optionally saturated or unsaturated aliphatic radical, R2 represents hydrogen,... | 12/11/1979 |
| 4177277 | Method for alleviating hypertension A method for alleviating or reducing angiotensin related hypertension in hypertensive mammals comprises administering an effective amount of a compound having the general formula ##STR1## Intermediates for the preparation of such compounds are also i... | 12/04/1979 |
| 4173644 | Thiourea compounds, compositions and methods and use The compounds are dithiocarbamates and isothioureas which are histamine H2 -antagonists. Two compounds of the invention are 2-(5-methyl-4-imidazolylmethylthio)ethyl N-methyldithiocarbamate and S-[2-(5-methyl-4-imidazolyl-methylthio)ethyl]-N-cya... | 11/06/1979 |
| 4166845 | Antidandruff shampoo compositions containing an aminopolyureylene resin This invention relates to a high-foaming antidandruff shampoo having desirable cosmetic conditioning properties, which consists essentially of about 10% to 30% by weight of a water-soluble betaine detergent, 1% to 10% by weight of a water-soluble anionic,... | 09/04/1979 |
| 4143137 | Substituted arylcyanoalkyl and diarylcyanoalkylimidazole metal salt complexes and fungicidal compositions and methods utilizing them This invention relates to substituted arylcyanoalkyl and diarylcyanoalkylimidazoles, their acid addition salts and their metal salt complexes and their use as broad spectrum protectant-eradicant fungicides.... | 03/06/1979 |
| 4118487 | Substituted azol-1-ylmethanes Azol-1-ylmethanes substituted on the methane carbon atom by (a) phenyl or lower alkyl and (b) by a biphenyl-4-yl, 4-phenoxyphenyl, 4-phenylthiophenyl, 4-phenylsulfinylphenyl or 4-phenylsulfonylphenyl group are antimycotic and antibacterial agents. The com... | 10/03/1978 |
| 4118502 | Amidinoformic and amidino-sulphinic acid derivatives Amidinoformic acids and amidinosulphinic acids which are histamine H2 -antagonists. Two specific compounds of the present invention are N-[2-(5-methyl-4-imidazolylmethylthio)-ethyl]amidinoformic acid and N-methyl-N'-[2-(5-methyl-4-imidazolylmet... | 10/03/1978 |
| 4118461 | 1-Substituted aralkyl imidazoles This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in particular are useful as systemic protectant/eradicant fungici... | 10/03/1978 |
| 4117142 | Disubstituted triphenylmethylmidazoles for treating mycotic infections Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro, Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen, and Z is methyl or chloro, or, when Y is methyl or chloro, Z is... | 09/26/1978 |
| 4115578 | 1-Substituted aralkyl imidazoles This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in particular are useful as systemic protectant/eradicant fungici... | 09/19/1978 |
| 4105762 | Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlling phytopathogenic fungi using them This disclosure describes novel aralkyl imidazoles, their acid addition salts, their metal complex salts and processes for their preparation. These compounds possess biological activity and in particular are useful as systemic protectant/eradicant fungici... | 08/08/1978 |
| 4104382 | Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors by administering an antihistamine and an H-2 histamine receptor inhibitor. Exemplary of the antihistamine in the compositions and methods of this invention is mepyramine... | 08/01/1978 |
| 4085209 | Preparation and safening effect of 1-substituted imidazole metal salt complexes This invention concerns the preparation of 1-substituted imidazole metal salt complexes and their use particularly as systemic fungicides. The preparation of the metal salt complexes of these imidazoles produces a safening effect, i.e., the ability to red... | 04/18/1978 |
| 4073922 | Treatment of rheumatoid arthritis and related diseases It is believed that rheumatoid arthritis and related collagen and auto-immune diseases are an infection and that various species of free-living (limax) amoebae are the aetiological agent of these diseases. It has been discovered that clotrimazole bis-phe... | 02/14/1978 |
| 4067989 | 1,3-Diazole heterocyclic compounds and their use as pesticides Plant fungicidal compounds of formula: ##STR1## WHEREIN R3 is alkyl, furyl, thienyl or phenyl, R4 is hydrogen, halogen, nitro, phenyl, alkoxy or alkyl, n is 1, 2 or 3, and Z is C=O or a derivative thereof; and their salts.... | 01/10/1978 |
| 4065572 | Amino acids and esters thereof useful as antihypertensive agents A compound of the formula ##STR1## possesses antihypertensive activity. Also provided are methods for the preparation of the compounds as well as pharmaceutical formulations and methods for their use as antihypertensive agents.... | 12/27/1977 |
| 4062965 | Quaternary imidazole compounds as microbicides This invention relates to novel compounds having the formula: ##STR1## wherein R1 is a straight-chain alkyl group having 8 to 18 carbon atoms, R2 is a straight-chain alkyl group having 1 to 3 carbon atoms, R3 is a str... | 12/13/1977 |
| 4058491 | Cationic hydrogels based on heterocyclic N-vinyl monomers Novel cationic hydrogels, containing basic (cationic) groups in their molecular structure, and processes for their preparation are described. These novel hydrogels are stable, three-dimensional polymer networks, having good water permeability and mechanic... | 11/15/1977 |
| 4034087 | Pharmaceutical composition and process of treatment A process for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc. comprising administering to humans, or domesticated animals, topically and/or systemically a composition comprising a pharmaceutical carrier and at least one ... | 07/05/1977 |
| 4024271 | Pharmacologically active guanidine compounds The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-guanidines which are inhibitors of histamine activity.... | 05/17/1977 |
| 3996370 | Antagonism of ethanol intoxication with 4[(4,5-dihydro-2-1H-imidazolyl)methoxy]-N,N,2-trimethylbenzenamine A novel method for combatting ethanol intoxication and narcosis in animals by administering an effective amount of the compound 4[(4,5-dihydro-2-1H-imidazolyl)methoxy]-N,N,2-trimethylbenzenamine or a pharmaceutically acceptable salt thereof internally to ... | 12/07/1976 |
| 3991201 | 1-(ଲ-Aryl-ଲ-R-ethyl)imidazoles as antimicrobial agents Compounds of the class of 1-(ଲ-aryl-ଲ-R-ethyl)imidazoles, useful as antibacterial and antifungal agents.... | 11/09/1976 |
| 3954982 | Pharmaceutical compositions and method of inhibiting H-1 and H-2 histamine receptors Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors by administering an antihistamine and an H-2 histamine receptor inhibitor. Exemplary of the antihistamine in the compositions and methods of this invention is mepyramine... | 05/04/1976 |
| 3949076 | N-(Heterocycl ic-alkyl)-9-xanthenylamines The compounds are N-(imidazolylalkyl, imidazolinylalkyl and tetrahydropyrimidylalkyl)-9-xanthenylamines which have gastric acid secretion inhibitory activity.... | 04/06/1976 |
| 3934022 | N-trityl-imidazoles as plant fungicides Plant fungicidal compositions are produced which comprise an amount of a compound of the formula: ##EQU1## wherein R is alkyl of 1 to 3 carbon atoms, sufficient to be effective for killing, combatting or controlling plant fungi, in combination with a... | 01/20/1976 |
