Quotables
"The horse is here to stay, the automobile is only a novelty - fad."
President of Michigan Savings Bank ; 1903
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5919792 | Integrin antagonists This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are v댣 antagonists, ... | 07/06/1999 |
| 5914324 | 6-Hydroxy and 6-oxo-androstane derivatives active on the cardiovascular system and pharmaceutical compositions containing same 6-hydroxy and 6-oxo-androstane derivatives of formula (I), active on the cardiovascular system. ##STR1## wherein: the symbol A represents CH--OR, C.dbd.N--OR, CH--CH.dbd.N--OR and C.dbd.CH--N--OR; and R1, R2 and R3 ar... | 06/22/1999 |
| 5914341 | Inhibitors of farnesyl-protein transferase The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invent... | 06/22/1999 |
| 5912261 | Carboxyalkyl heterocyclic derivatives Carboxyalkyl heterocyclic derivatives, pharmaceutically acceptable salts thereof, and therapeutic agents containing said compounds as an effective component are useful pharmaceuticals for the treatment of diabetic complications such as diabetic neuropathy... | 06/15/1999 |
| 5910507 | Methods for control and mitigation of molluscs A method is provided for controlling the proliferation of molluscs in target habitat by applying to the habitat a compound or mixture of compounds which are amines, ethoxylated amines, quaternary amines, ethoxylated quaternary amines and cyclic amines.... | 06/08/1999 |
| 5908856 | Cleaning compositions containing biostatic agent The present invention relates to an aqueous cleaning composition containing at least one biostatic agent, at least one surfactant and water.... | 06/01/1999 |
| 5905072 | Adjuvants for systemic fungicides, fungicidal compositions which contain them and their use Adjuvants for systemic fungicides in the form of a stable microemulsion comprise water, a mixture of methyl esters of fatty acids obtained by the transesterification of vegetable oils, an anionic surface-active agent, at least one non-ionic surface-active... | 05/18/1999 |
| 5902808 | Methods and compositions for controlling biofouling using N-alkyl heterocyclic compounds The present invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one N-alkyl heterocyclic compound to inhibit bacterial adhesion to the s... | 05/11/1999 |
| 5900393 | Scalp care products containing anti itching /anti irritant agents Mild aqueous detergent, e.g., shampoo, compositions are disclosed based on a mixture comprising anionic surfactant and amphoteric surfactant, such as betaines, present in the composition at a level of from about 0.75 to 1.25 parts by weight per part by we... | 05/04/1999 |
| 5889038 | Methods and products for treating diarrhea and scours: use of clotrimazole and related aromatic compounds A method and product for treating and preventing diarrhea and scours is provided. The method involves treating a subject who has diarrhea, or scours, or is at risk of getting diarrhea or scours with an aromatic compound of the invention. The products of t... | 03/30/1999 |
| 5883106 | 5-lipoxygenase inhibitors Novel compounds having the ability to inhibit 5-lipoxygenase enzyme and having the following formula I: ##STR1## and the pharmaceutically acceptable salts thereof, wherein Ar1 is a heterocyclic moiety which is selected from imidazolyl, pyr... | 03/16/1999 |
| 5869474 | Low dosage treatment for cocaine craving and withdrawal Ketoconazole is used for treating cocaine addiction. Mammals, including humans, that are chronically addicted to cocaine are treated with ketoconazole to decrease self-administration of the drug.... | 02/09/1999 |
| 5866598 | Medicament for treating or preventing cerebrovascular dementia Compounds for treating or preventing cerebrovascular diseases are disclosed. These compounds are 5-HT antagonists. More specifically, these compounds, when combined with pharmaceutically acceptable carriers or excipients and administered to animals includ... | 02/02/1999 |
| 5866576 | Epoxide-containing compounds Disclosed are enantiomers, diastereomers, salts, solvates, hydrates and mixtures thereof, of formula I: ##STR1## The core moiety is a monocyclic ring structure having five to six ring atoms and two nitrogen atoms at the 1 and 3 positions, n is an int... | 02/02/1999 |
| 5866601 | Carbocyclic compounds Novel carbocyclic compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of... | 02/02/1999 |
| 5859018 | Method for treating diseases mediated by cellular proliferation in response to PDGF, EGF, FGF, and VEGF There is disclosed a method for: (1) inhibiting new blood vessel formation that is useful for treating or preventing progression of diabetic retinopathy, cavernous haemangiomas, Kaposi's sarcoma, tumors composed of endothelial-like cells, and growth of ca... | 01/12/1999 |
| 5859034 | Tri-substituted phenyl compounds which have useful pharmaceutical activity Tri-substituted phenyl derivatives having the general formula (I): ##STR1## In a preferred embodiment, Y is preferably an --XRa group, X is preferably --O--, Z is preferably an --XR5 group, Ra is preferably hydrogen o... | 01/12/1999 |
| 5855654 | Pyridazinones as marine antifouling agents Disclosed is a method of inhibiting the growth of marine organisms on a marine structure, by applying dihydropyridazinone and pyridazinone compounds onto or into the marine structure. These compounds may be directly incorporated into the marine structure ... | 01/05/1999 |
| 5854268 | Azetidine, pyrrolidine and piperidine derivatives A class of substituted azetidine, pyrrolidine and piperidine derivatives are selective agonists of 5-HT1 -like receptors, being potent agonists of the human 5-HT1D receptor subtype whilst possessing at least a 10-fold selecti... | 12/29/1998 |
| 5852045 | Fibrinogen receptor antagonists Fibrinogen receptor antagonists having the structure, for example, of ##STR1## for example ##STR2##... | 12/22/1998 |
| 5849740 | Methods for using ketoconazole and related substances in medicaments for treatment of type II diabetes The present invention is a method of using ketoconazole or molecules resembling ketoconazole with comparable biological activity for the manufacture of drugs and for medical treatment of diabetes mellitus type II as well as for counteracting the other ris... | 12/15/1998 |
| 5849775 | Substituted benzoylguanidines process for their preparation, their use as a medicament or diagnostic, and pharmaceutical containing them Benzoylguaridines of the formula I ##STR1## are described in which: R(1), R(2), R(3), R(4), R(5) are as defined in the specification, and pharmaceutically tolerated salts thereof.... | 12/15/1998 |
| 5849727 | Compositions and methods for altering the biodistribution of biological agents This invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic or bioactive agents. The methods and composition of the invention can be used with several therapeutic or bioactive agents and can achieve site-... | 12/15/1998 |
| 5834409 | Scalp care products containing anti itching/anti irritant agents Mild aqueous detergent, e.g., shampoo, compositions are disclosed based on a mixture comprising anionic surfactant and amphoteric surfactant, such as betaines, present in the composition at a level of from about 0.75 to 1.25 parts by weight per part by we... | 11/10/1998 |
| 5830915 | Phosphinic acid amides as matrix metalloprotease inhibitors The invention provides compounds which are useful as inhibitors of matrix metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having... | 11/03/1998 |
| 5830854 | Method of treating cystic fibrosis using a tachykinin receptor antagonist Tachykinin receptor antagonists are useful for the treatment of cystic fibrosis.... | 11/03/1998 |
| 5821259 | H3 -receptor agonists as therapeutic agents The invention provides a method for preventing and alleviating the harmful biological effects of secretion of chemicals from mast cells in the organism of mammals which leads to clinical conditions namely allergy, asthma, arthritis, dermatitis, interstiti... | 10/13/1998 |
| 5817690 | 4-aminoethoxy indolone derivatives A compound of the formula I: ##STR1## in which Y is hydrogen, halogen or lower alkoxy; R1 is hydrogen, lower alkyl or aryl(lower)alkyl; R2 is hydrogen, lower alkyl or --(CH2)n Xp Ar, where X is o... | 10/06/1998 |
| 5811444 | Compositions for reducing abnormal stimulation of endothelin receptors and novel compounds The invention relates to the new use and the new products of formula (I): ##STR1## in which: R1 =represents hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, formyl, cycloalkyl, optionally interrupted by heteroatoms, R2, R3 | 09/22/1998 |
| 5807878 | Tetrasubstituted imidazoles A compound of the formula ##STR1## wherein the substituents are defined in the specification useful for the treatment of cardiovascular disorders.... | 09/15/1998 |
| 5795907 | Gastin and CCK receptor ligands Compounds of formula (Ia), (Ib), or (Ic), wherein A represents a group having two fused rings, or a group of formula (Id), R1.sub.(m) represents up to 6 substituents, K represents --O--, --S--, --CH2 --, --N(R2)-- or --N(C... | 08/18/1998 |
| 5795898 | Method for treating diseases mediated by cellular proliferation in response to PDGF,EGF,FGF and VEGF There is disclosed a method for: (1) inhibiting new blood vessel formation that is useful for treating or preventing progression of diabetic retinopathy, cavernous haemangiomas, Kaposi's sarcoma, tumors composed of endothelial-like cells, and growth of ca... | 08/18/1998 |
| 5789432 | Aromatase-inhibiting composition containing azole derivative The disclosure describes a pharmaceutical composition comprising an aromatase-inhibiting effective amount of a compound selected from the group consisting of compounds of the formula (I): ##STR1## including their stereoisomers and salts thereof, wher... | 08/04/1998 |
| 5767138 | Pharmaceutical composition for inhibiting the growth of viruses and cancers A pharmaceutical composition that inhibits the growth of tumors and cancers in mammals and can be used to treat viral infections that comprises a fungicide is disclosed. The particular fungicide used is a benzimidazole derivative.... | 06/16/1998 |
| 5767151 | 3,3-(disubstituted) cyclohexan-1-ylidine acetate dimers and related compounds The present invention relates to novel 3,3-(disubstituted)-cyclohexan-1-ylidene acetate dimers of Formula (I): ##STR1## and related compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammateor... | 06/16/1998 |
| 5760029 | Spirocycle integrin inhibitors This invention relates to novel heterocycles, including (S)-2-phenylsulfonylamino-3-8-(2-pyridinylaminomethyl)-!-1-oxa-2-azaspi ro-4,5!-dec-2-en-3-yl!carbonylamino! propionic acid, which are useful as antagonists of the v ଲ | 06/02/1998 |
| 5753687 | Modulators of proteins with phosphotryrosine recognition units Y--X--C(R').dbd.C(R")COOR'" (A1) The present invention relates to novel protein tyrosine phosphatase modulating compounds having the general structure shown in Formula (A1), to methods for their preparation, to compositions compr... | 05/19/1998 |
| 5747542 | Oxo-substituted tetrahydronaphthalene derivatives having retinold and/or retinoid antagonist-like biological activity Compounds of the formula ##STR1## where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity.... | 05/05/1998 |
| 5739148 | 6-(2-Imidazolinylamino) quinoline compounds useful as alpha-2 adrenoceptor agonists The subject invention relates to compounds having the structure: ##STR1## wherein: (a) R is unsubstituted C1 -C3 alkanyl or alkenyl; (b) R' is selected from unsubstituted C1 14 C3 alkanyl or alkenyl; unsubstitut... | 04/14/1998 |
| 5731335 | (1-Heteroazolyl-1-heterocycane derivatives and their use as neuroprotective agents This invention provides heterocyclic compounds of formula (I) that are potentially useful in the treatment of neuropsychiatric disorders associated with progressive processes leading to neuronal necrosis and dysfunction. In particular, the novel compounds... | 03/24/1998 |
