Class 514/39 - Three or more saccharide radicals (e.g., neomycin, etc.)

Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the cyclohexyl radical is bonded
No. of patents: 117
Last issue date: 10/25/2011

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Number	Title	Issue Date
8044031	Method for increasing the survival of aquatic and other animals exposed to an aquatic virus, birnavirus or other RNA virus and composition for such methods A method of increasing the survival of animals and aquatic species susceptible to birnavirus infection by treating them before, during and/or after birnavirus exposure, with a chemical compound capable of inhibiting viral replication. A method of treating aquatic sp...	10/25/2011
7829543	Substituted polyamines as inhibitors of bacterial efflux pumps Disclosed are methods of treating bacterial infections including those caused by multidrug resistant bacteria using polyamine efflux pump inhibiting compounds, including for example N-benzylated polyazaalkanes, N-benzylated polyaminoalkanes, or mixed N-benzylated po...	11/09/2010
7635685	Bifunctional antibiotics for targeting rRNA and resistance-causing enzymes and for inhibition of anthrax lethal factor A novel group of aminoglycosides which share some structural features of currently available aminoglycosides with regard to the backbone, while also having significant structural differences, is disclosed. The similarity enables these aminoglycosides to be highly po...	12/22/2009
7404964	Injectable compositions for the controlled delivery of pharmacologically active compound The present invention provides compositions and methods for extending the release times and lowering the toxicity of pharmacologically active compounds. The compounds comprise a salt of the pharmacologically active compound with a lipophilic counterion and a pharmac...	07/29/2008
7368102	Pulmonary delivery of aminoglycosides The present invention is directed to the administration of aminoglycosides. In particular, the present invention is directed to compositions and methods for the pulmonary administration of aminoglycosides. According to a preferred embodiment, compositions and method...	05/06/2008
7345024	Pharmaceutical preparation, method for its production as well as its use The invention relates to hardly soluble antiphlogistic salts and antiphlogistic-antibiotic pharmaceutical preparations and their use. The hardly water soluble antiphlogistic antibiotics salts have as their cationic component one of the antibiotics gentamicin, clinda...	03/18/2008
7259261	Racemization and enantiomer separation of clopidogrel Processes for separation of enantiomers of clopidogrel, and converting one enantiomer of clopidogrel to another enantiomer of clopidogrel are provided. The enantiomers are separated by crystallizing the (S) enantiomer as camphor sulfonate salt from a hydrocarbon, or...	08/21/2007
7244712	Aminoglycoside antibiotics and methods of using same The present invention relates to aminoglycoside compounds having antibiotic activity. Moreover, the present invention relates to L-aminoglycoside compounds and diastereomers thereof which posses antibiotic activity and are not susceptible to development of resistant...	07/17/2007
7128897	Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis Pharmaceutical compositions are described that contain one agent for treatment of sinusitis and a surfactant. The compositions are prepared to have a surface tension that renders the composition effective for treatment of sinusitis. ...	10/31/2006
7115577	Colorectal neoplasia prophylaxis Development of colorectal neoplasia in a patient subject or predisposed to colorectal neoplasia is reduced by the steps of (a) determining a patient is subject or predisposed to colorectal neoplasia; and (b) enterically delivering into the gut of the person an effec...	10/03/2006
7109294	Bacterial glycosyltransferase polypeptides involved in antibiotic resistance Disclosed are various genes encoding proteins that are shown to play a role, direct or indirect, in microbial resistance of an organism in a biofilm and homologs thereof. Also disclosed are methods of identifying a compound that modulates microbial resistance of an ...	09/19/2006
7091314	Intermediates and methods for making heptapeptide oxytocin analogues More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates use...	08/15/2006
6946137	Methods for the controlled delivery of pharmacologically active compounds The present invention provides compositions and methods for extending the release times and lowering the toxicity of pharmacologically active compounds. The compounds comprise a salt of the pharmacologically active compound with a lipophilic counterion and a pharmac...	09/20/2005
6914141	Clopidogrel bisulfate tablet formulation Pharmaceutical tablets comprising clopidogrel bisulfate and a lubricant selected from zinc stearate, stearic acid, and sodium stearyl fumarate. ...	07/05/2005
6887487	Injectable compositions for the controlled delivery of pharmacologically active compound The present invention provides compositions and methods for extending the release times and lowering the toxicity of pharmacologically active compounds. The compounds comprise a salt of the pharmacologically active compound with a lipophilic counterion and a pharmac...	05/03/2005
6858589	Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at least 4 mg/l of...	02/22/2005
6846807	Colorectal neoplasia prophylaxis Development of colorectal neoplasia in a patient subject or predisposed to colorectal neoplasia is reduced by the steps of (a) determining a patient is subject or predisposed to colorectal neoplasia; and (b) enterically delivering into the gut of the person an effec...	01/25/2005
6818625	Method for increasing survival rate of cells in animal cell culture under hypoxia condition The present invention relates to a method for increasing survival rate of cells in animal cell culture under hypoxia condition by adding antibiotics to the culture media. The method of present invention comprises a step of culturing animal cells in culture media con...	11/16/2004
6737411	Racemization and enantiomer separation of clopidogrel Processes for separation of enantiomers of clopidogrel, and converting one enantiomer of clopidogrel to another enantiomer of clopidogrel are provided. The enantiomers are separated by crystallizing the (S) enantiomer as camphor sulfonate salt from a hydrocarbon, or...	05/18/2004
6716822	Therapeutic agent for ischemia which inhibits apoptosis under ischemic condition The present invention relates to a therapeutic agent for ischemia which inhibits apoptosis under ischemic condition. The therapeutic agent of the present invention comprises antibacterial agents of quinolones, quinones, aminoglycosides or chloramphenicol as an activ...	04/06/2004
6706290	Methods for eradication of nanobacteria Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The present invention provides methods for sterilizing articles contaminated ...	03/16/2004
6664233	Combination therapy including 9-nitro-20(S)-camptothecin and bleomycin A method for treating a patient having a disease associated with undesirable or uncontrolled cell proliferation such as cancer and restenosis is provided. The method comprises: delivering to the patient a therapeutically effective amount of 9-nitro-20(S)-...	12/16/2003
6645508	Stable L-ascorbic acid composition A stable composition including a water-sensitive pharmacologically active agent, such as an enzyme, an antibiotic or a vitamin, a hydrophilic non-polar primary solvent, an optional hydrophilic non-polar secondary solvent and optional pharmaceutical or cos...	11/11/2003
6482802	Use of neomycin for treating angiogenesis-related diseases The present invention is directed to using neomycin or an analogue thereof as an therapeutic agent to treat angiogenesis-related diseases, which are characterized by excessive, undesired or inappropriate angiogenesis or proliferation of endothelial cells....	11/19/2002
6475993	Treatment of hereditary diseases with gentamicin This invention relates to a method of treating an inherited disease due to a point mutation producing a stop codon by administering an effective dose of an aminoglycoside antibiotic or a derivative thereof. Mdx mouse, which is an animal model for Duchenne...	11/05/2002
6475992	Methods of and compositions for potentiating the action of agents active on cell wall sites of the susceptible bacteria The invention provides a method of potentiating the activity of antibacterial agents that act on bacterial cell walls, comprising the step of administering to a subject an antibacterial agent and an aminoglycoside to attain a peak concentration of at leas...	11/05/2002
6387886	Method for the treatment of severe chronic bronchitis (bronchietasis) with an aerosolized antibiotic The present invention is directed to a method for the treatment of severe chronic bronchitis, i.e., bronchiectasis, using a concentrated aminoglycoside antibiotic formulation delivering the antibiotic to the lung endobronchial space, including alveoli, in...	05/14/2002
6337325	Combined preparation for the therapy of immune diseases A combination preparation comprising a compound which has a phosphodiesterase-inhibiting action, and a compound which reduces the biologically effective intracellular Ca2+ content, is suitable for the treatment of immunological diseases....	01/08/2002
6274555	Composition and method for topical animal medication A composition for topically treating epidermal abrasions in animals is provided consisting of bacitracin zinc utilized in a ratio of 300 milligrams, neomycin utilized in a ratio of 35 milligrams, polymycin-B sulfate in a ratio of 10,000 milligrams, and pr...	08/14/2001
6248718	Lesion-directed dry dosage forms of antibacterial agents for the treatment of acute mucosal infections of the oral cavity The invention provides a medicament for topically treating acute bacterial infections in the oral mucosa, and methods of use. The medicament comprises a dry dosage (such as a troche or powder) of one or more antibacterial agents and, preferably, one or mo...	06/19/2001
6245746	Efflux pump inhibitors Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds....	06/12/2001
6180612	Methods and compositions for targeting DNA metabolic processes using aminoglycoside derivatives Protein targets for disease intervention through inhibition of nucleic acid metabolism are disclosed. Novel polypeptides for one such target, DNA-dependent ATPase A, and novel polynucleotides encoding DNA-dependent ATPase A are disclosed. Phosphoaminoglyc...	01/30/2001
6114310	Efflux pump inhibitors Compounds are described which have efflux pump inhibitor activity. Also described are methods of using such efflux pump inhibitor compounds and pharmaceutical compositions which include such compounds....	09/05/2000
6066676	Pharmaceutical composition and methods for using it Disclosed is a method of treating problems or disorders of the human nervous system or a method of imparting an anaesthetic effect, by applying to a patient in need of such treatment a pharmaceutical composition adapted for tropical application to human s...	05/23/2000
6037140	Selective media for the culture and isolation of gram bacteria, antibiotic composition This invention relates to a selective medium for the culture and isolation of Gram- bacteria comprising at least one antibiotic specifically active against Gram+ bacteria and at least one bacteriocin....	03/14/2000
5993841	Pharmaceutical composition and methods for using it Disclosed is a method of treating problems or disorders of the human nervous system or a method of imparting an anaesthetic effect, by applying to a patient in need of such treatment a pharmaceutical composition adapted for topical application to human sk...	11/30/1999
5981499	Lesion-directed antibiotics in dry dosage forms for the treatment of shallow ulcers of the oral mucosa The invention provides a medicament for topically treating aphthous ulcers in the oral mucosa, and methods of use. The medicament comprises a troche or powder comprising a dry dosage of one or more antibiotics and, preferably, one or more polyvalent metal...	11/09/1999
5929039	Method for treating cardiac dysfunction and pharmaceutical compositions useful therefor The present invention relates generally to a method for, and pharmaceutical compositions useful in, the prophylaxis and/or treatment of cardiac dysfunction in a mammal by the administration of an effective amount of an agent capable of blocking or inhibit...	07/27/1999
5900406	Use of antibiotics of the type 2-deoxystreptamine substituted with aminosugars to inhibit growth of microorganisms containing group I introns The invention described herein provides for methods of screening for compounds that can be used to prevent or inhibit the growth of microbial eukaryotes, particularly plant or animal pathogens. The screening methods of the invention involve the step of sc...	05/04/1999
5883074	Potentiators of antibacterial agents Methods for screening for compounds which potentiate the activity of antibacterial agents against bacteria resistant to the antibacterial agent alone, pharmaceutical compositions including such potentiators, and methods of treating bacterial infections us...	03/16/1999

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Class 514/39 - Three or more saccharide radicals (e.g., neomycin, etc.)