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| Number | Title | Issue Date |
| 4145422 | Aminomethylene oxindoles This invention provides aminomethylene oxindole compounds represented by the formula ##STR1## wherein R is H or loweralkyl; R' is loweralkyl, aralkyl, or R and R' taken together form a chain of the formula wherein X is CH2 or NR" where R" ... | 03/20/1979 |
| 4139634 | Indole derivatives and process for preparing the same Indole derivatives of the formula: ##STR1## wherein R1 represents a hydrogen atom or a methyl radical, R2 and R3, which are the same or different, each represent a hydrogen atom, a methyl or ethyl radical, a benzyl ra... | 02/13/1979 |
| 4137331 | 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones This invention provides new compounds of formula I, ##STR1## wherein Het is a radical formed by removing one of the hydrogens from the phenyl ring of 2-indolinone or fluorenone, and R is the group A, B, C or D, ##STR2## wherein N IS THE NUMBER 2... | 01/30/1979 |
| 4131680 | Hypotensive sulphonamidopiperidyl indoles This invention relates to compounds having the general formula: ##STR1## WHEREIN W represents a phenyl or indolyl radical, either of which radicals may be unsubstituted or substituted by halogen, lower alkyl, lower alkoxy or hydroxy. A represents a l... | 12/26/1978 |
| 4131673 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 12/26/1978 |
| 4126684 | 4-Amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse 4-Amino-3-p-halophenylbutyric acids, acyl derivatives, esters and/or salts thereof reduce addiction liability, particularly that of narcotics, or the withdrawal symptoms observed after interruption of prolonged use of addicting agents, especially of narco... | 11/21/1978 |
| 4110459 | Benzoylpiperidylalkylindoles in alleviating pain New benzoylpiperidylalkylindoles and related compounds possessing tranquilizing, anti-hypertensive and analgesic properties and a process for the preparation thereof are described.... | 08/29/1978 |
| 4101663 | Benzoylpiperidylalkylindoles New benzoylpiperidylalkylindoles and related compounds possessing tranquilizing, anti-hypertensive and analgesic properties and a process for the preparation thereof are described.... | 07/18/1978 |
| 4073911 | Indolylalkylpiperidines 1-(Indolyl-3-alkyl)-3 or 4-(ureido or guanidino)-piperidines, e.g. those of the formula ##STR1## R= H; alkyl; free, etherified or esterified OH or SH; CF3, NO2 or NH2 m= 1-4; n= 2 or 3; X= O, S or NH acyl derivatives... | 02/14/1978 |
| 4066780 | Pyranoindole derivatives as antiulcer agents Pyranoindole and thiopyranoindole derivatives characterized by having an amino(lower)alkyl radical attached to either or both the 1 and 9 position of a pyrano[3,4-b]indole or thiopyrano[3,4-b]indole nucleus or having said radical attached to the 1 positio... | 01/03/1978 |
| 4066779 | Pyranoindole derivatives, compositions and method of use Pyranolindole and thiopyranoindole derivatives characterized by having an amino(lower)alkyl radical attached to either or both the 1 and 9 position of a pyrano[3,4-b]indole or thiopyrano[3,4-b]indole nucleus or having said radical attached to the 1 positi... | 01/03/1978 |
| 4066773 | N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.... | 01/03/1978 |
| 4064255 | Compositions containing new indole derivatives and their use in pharmacology Compositions containing indole derivatives of the formula ##STR1## are useful in pharmacology.... | 12/20/1977 |
| 4053615 | Phthalimidopiperidines and anti-convulsant compositions thereof Phthalimidopiperidines of the formula ##STR1## are described where R1 is hydrogen, lower alkyl, cycloalkyl of 5 to 7 carbon atoms, phenyl(lower)alkyl, pyridyl(lower)alkyl, furyl(lower)alkyl or thienyl(lower)alkyl and R2 and R | 10/11/1977 |
| 4046900 | Benzoylpiperidylalkylindoles New benzoylpiperidylalkylindoles and related compounds possessing tranquilizing, anti-hypertensive and analgesic properties and a process for the preparation thereof are described.... | 09/06/1977 |
| 4045566 | Piperidyl-glycylamide derivatives This invention relates to compounds having the general formula: ##STR1## wherein W represents a phenyl or indolyl radical, either of which radicals may be unsubstituted or substituted by halogen, lower alkyl, lower alkoxy or hydroxy; A represents a l... | 08/30/1977 |
| 4031221 | Method of treating pain and hypertension 3-[2-(Phenyloxycycloazalkyl)ethyl]indoles possessing antihypertensive, analgesic, and tranquilizing properties and process for their preparation are described.... | 06/21/1977 |
| 4017624 | N-(ω-Amino)alkylaniline derivatives An N-(ω-amino)alkylaniline derivative of the formula: ##STR1## and its pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## with a compound of the formula:... | 04/12/1977 |
| 4015002 | 1-Aryl-2-oxo-2,4,5,6,7,7a-hexahydro-indoles, salts, pharmaceutical compositions and methods of use This invention relates to 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydro-indoles, and acid addition salts thereof. In particular, the compounds have (ଲ-aminoethoxy- or γ-amino-propoxy)-phenyl substituents, the amino groups in each case either being joined to ... | 03/29/1977 |
| 4000304 | Diuretic antiturombogenic and antiarrhythmic processes using N-substituted indole dimers and pyrrolobenzodia-zepine rearrangement products thereof 2-(2- or 3-Indolyl)indolines, unsubstituted and carbon substituted, condense with N-mono substituted carboxamides or with lactams under the influence of phosphorus oxychloride to produce 1-(N-substituted iminoalkyl)-2-(2- or 3-indolyl)indolines. The ... | 12/28/1976 |
| 4000287 | Isoindolinopiperidines 1-(3-Aryloxy-2-hydroxypropyl)-3- or 4-(1-oxoisoindolino)-piperidines, e.g. those of the formula ##STR1## 2-ALKANOIC ACID ESTERS AND ACID ADDITION SALTS THEREOF ARE ANTIHYPERTENSIVE AND ANTIARRHYTHMIC AGENTS.... | 12/28/1976 |
| 3993764 | Treatment of depressive states and Parkinson's disease Novel compositions having antidepressive, antiemetic and anti-Parkinson activities comprising an effective amount of at least one compound selected from the group consisting of 3-(4'-piperidyl)-indoles of the formula ##SPC1## Wherein R is selected fr... | 11/23/1976 |
| 3950527 | N-[ω-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides N-[ω-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides of the formula ##SPC1## Wherein R is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms, R1 and R2 are individually selected from the group consisting... | 04/13/1976 |
| 3947578 | Omega-[4-(3"-indolyl)-piperidino]-alkyl-arylketones as nevroleptics Novel [4'-(3"-indolyl)-piperidino]-alkyl-arylketones of the formula ##SPC1## Wherein R is selected from the group consisting of hydrogen and alkoxy of 1 to 5 carbon atoms, R1 and R2 are individually selected from the group consisting... | 03/30/1976 |
