Class 514/315 - Piperidines

Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the six-membered hetero ring, consisting
No. of patents: 854
Last issue date: 05/01/2012

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Number	Title	Issue Date
6323220	Substituted pyridine or piperidine compounds The invention relates to a compound of formula (I): ##STR1## wherein: A represents pyridine, pyridinium or piperidine R1, R2, R3 and R4 are as defined in the description R5 represents hydrogen, a nitrogen-conta...	11/27/2001
6323038	Diagnostic reagent for complications associated with diabetes or renal failure In view of the situation of the prior art, the present invention specifies the structure of a late-stage product of Mailard reaction in vivo having a close relation with various tissue disorders, and provides a diagnostic reagent for complications associa...	11/27/2001
6313132	Therapeutically active diarylpropylamines; their pharmaceutically acceptable salts; a method for their preparation and method for their use The invention relates to novel compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and Ar are as defined in claim 1, their salts with physiologically acceptable acids and, whe...	11/06/2001
6306912	Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases Method for identifying a compound useful for the therapeutic treatment of a neurological disease or disorder such as stroke, head trauma, spinal cord injury, epilepsy, anxiety, or neurodegenerative diseases such as Alzheimer's Disease, Huntington's Diseas...	10/23/2001
6306848	Method of modifying wrinkles using guanidine derivatives The invention relates to wrinkling modifiers and anti-aging cosmetic compositions which each comprise a guanidine derivative represented by the following general formula (1): ##STR1## wherein ##STR2## is a heterocyclic group selected from azetidine, ...	10/23/2001
6303620	Compounds with growth hormone releasing properties Disclosed are 4,4-disubstituted and 3,3-disubstituted piperidine compounds of formula I ##STR1## wherein D, E, G, J, R1, a, b, c, and d are defined in the specification, compositions containing them, and their use for treating medical diso...	10/16/2001
6300333	Substituted piperidines, processes for their preparation and their use as pesticides and fungicides Substituted piperidines, processes for their preparation and their use as pesticides and fungicides. The invention relates to substituted piperidines of the formula ##STR1## in which R1 is H, halogen, alkyl, haloalkyl or cycloalkyl; R2 an...	10/09/2001
6297290	Composition containing a nerve fiber reactivity modulating compound The present invention relates to a novel aqueous composition based on a compound modulating the reactivity of nerve fibers. It relates more particularly to a pharmaceutical composition for topical use on a human or animal body and intended to anesthetize ...	10/02/2001
6294533	Calcium channel blockers Compounds of the formula ##STR1## wherein m is 0, 1 or 2; wherein when m is O, Z is O, when m is 1, Z is N, and when m is 2, Z is C; Y is H, OH, NH2, or an organic moiety of 1-20C, optionally additionally containing 1-8 heteaoms selected from te gro...	09/25/2001
6284788	Use of known agonists of the central cannabinoid receptor CB1 The present invention relates to the use of known agonists of the central cannabinoid receptor CB1 for the prophylaxis and treatment of neurodegenerative disorders, in particular for the treatment of cerebral apoplexy and craniocerebral trauma....	09/04/2001
6281211	Substituted semicarbazides and the use thereof This invention is related to substituted semicarbazides represented by Formula (I) or a pharmaceutically acceptable salt or prodrug thereof, wherein: R1 and R2 are independently hydrogen, alkyl, cycloalkyl, alkenyl, alkynyl, haloalky...	08/28/2001
6277836	Methods and compositions for treating inflammatory bowel disease The present invention provides a method and composition of medications use to treat inflammatory bowel disease. The invention further provides combinations of anti-atypical mycobacterial agents effective against the atypical mycobacterial strains. It also...	08/21/2001
6274632	Derivatives of 4,4-difluorobut-3-enylsulfinic acid and their use as pesticides The invention relates to compounds of the formula (I): CF2.dbd.CX--CH.sub.2 --CH2 --S(O)--R wherein X represents hydrogen, halogen or lower alkyl, and R represents a group OR1 or NR2 R3 wherein R...	08/14/2001
6274598	Methods for treating antibiotic-resistant infections This invention relates to the treatment of antibiotic-resistant infections, including particularly infections caused by bacteria, Mycobacteria and fungi. A preferred group of compositions of the invention contain as active agents compounds containing pyri...	08/14/2001
6274597	Method of enhancing lysosomal ଱-Galactosidase A A method of enhancing the activity of lysosomal ଱-Galactosidase A (଱-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds....	08/14/2001
6274580	Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus Compounds selected from the group consisting of formulae I, II, III, IV, VI, VII, and VIII ##STR1## wherein R is H or NH2, and pharmacologically acceptable salts thereof, are suitable for use in methods for treating non-insulin-dependent d...	08/14/2001
6274570	Pesticidal compositions A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a) a castor oil ethoxylate having 30-50 mol ethoxylate, (b) a...	08/14/2001
6274617	Heterocyclic ester and amide hair growth compositions and uses This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides....	08/14/2001
6271230	Use of NK-1 receptor antagonists for treating cognitive disorders The present invention provides methods for the treatment or prevention of cognitive disorders which comprises oral administration of an orally active, long acting, CNS-penetrant NK-1 receptor antagonist and pharmaceutical compositions comprising such a NK...	08/07/2001
6265404	Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the ...	07/24/2001
6265434	Pyrrolidine modulators of chemokine receptor activity The present invention is directed to pyrrolidine compounds of the formula 1: ##STR1## (wherein R1, R2, R3, R4, R5, R6 and n are defined herein) which are useful as modulators of chemokine r...	07/24/2001
6262072	Orally administered antimicrobial pharmaceutical formulations of ciprofloxacin The invention provides three orally administered ciprofloxacin formulations: The first formulation comprises 60-75 wt % of ciprofloxacin or at least one of pharmacologically acceptable salt; 0.3-10 wt % of pregelatinized starch as binder; 5-30 wt % of lac...	07/17/2001
6258807	Method for treating pain The present invention provides a method for treating pain comprising administering an analgesic dosage of olanzapine to an animal in need of such treatment....	07/10/2001
6258827	Combinations for the treatment of parkinsonism containing selective NMDA antagonists This invention relates to a method of treating Parkinson's Disease whereby a mammal suffering from Parkinson's Disease is treated with a combination of a forebrain selective NMDA antagonist and a compound which is capable of increasing the excitatory feed...	07/10/2001
6251892	N-oxides of heterocyclic esters, amides, thioesters, and ketones This invention relates to neurotrophic low molecular weight, small molecule N-oxides of heterocyclic esters, amides, thioesters, and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with...	06/26/2001
6251940	Inflammatory cell inhibitors Compounds of general formula (I) ##STR1## wherein R4 is an ester or thioester group and R, R1, R2, and R3 are as specified in the description, inhibit monocyte and/or macrophage and/or lymphocyte activation and ...	06/26/2001
6248356	Immunotherapeutic anti-cancer pharmaceutical compositions There is disclosed a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having a mechanism of action as spermine antagonists. The present pharmaceutical compositions are able to inhibit the inhibitory e...	06/19/2001
6245360	Nutritional supplement A single entity product is provided for administration to persons being treated for nutritional deficiencies associated with addiction to alcohol, wherein the product is an extended-release multivitamin with minerals and trace elements in beneficial dose ...	06/12/2001
6242450	5-HT1F antagonists This invention provides 5-HT1f antagonists of Formula I: ##STR1## where AR1, AR2, R, and R' are as defined in the specification....	06/05/2001
6239175	Carbamoyloxy derivatives of mutiline and their use as antibacterials Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the...	05/29/2001
6239145	Nitroxyl compounds and drugs and reagents containing the same as the active ingredient Nitroxyl compounds represented by general formula (I) which are usable in acquiring information about active oxygen or in vivo free radicals as biological images such as magnetic resonance images or magnetoencephalograms, wherein A represents hydrogen or ...	05/29/2001
6239144	Methods of treating bone loss The present invention provides methods of treating or preventing conditions associated with a lack of parathyroid hormone comprising administering to a mammal in need thereof an effective amount of a compound having activity as a tachykinin receptor antag...	05/29/2001
6235755	FSH mimetics for the treatment of infertility The present invention provides non-peptidic amino derivatives, their therapeutic use as well as pharmaceutical compositions that possess activity as Follicle Stimulating Hormone (FSH) agonists and are useful in the for treatment of infertility. In particu...	05/22/2001
6235754	Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites The present invention relates to methods and compositions for treating animals and humans, and for controlling, preventing and protecting animals and humans from infestation and infection by arthropod and helminth parasites by administering or applying to...	05/22/2001
6235737	Reduction of hair growth Mammalian hair growth is reduced by applying to the skin a composition that increases cellular ceramide levels....	05/22/2001
6235757	Substituted heterocycles Compounds of formula I ##STR1## wherein Q1, Q2, Q3, Q4 and Q5 have any of the meanings given in the specification, their N-oxides, and their pharmacuetically acceptable salts are nonpeptide antagonist...	05/22/2001
6221377	Administration media for analgesic, anti-inflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs Administration mediums comprising solutions of nitrous oxide in water, alcohols, ethers or oils, and optionally including essential fatty acids or C1 -C6 alkyl esters thereof enhance the action of analgesic, anti-inflammatory and ant...	04/24/2001
6218424	Heterocyclic ketone and thioester compounds and uses This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged ner...	04/17/2001
6214857	Substituted alkanohydroxamic acids and method of reducing TNF଱ levels Imido and amido substituted alkanohydroxamic acids reduce the levels of TNF଱ and inhibit phosphodiesterase in a mammal. A typical embodiment is 3-(3-cyclopentyloxy-4-methoxyphenyl)-N-hydroxy-3-phthalimidopropionamide....	04/10/2001
6214837	Pharmaceutical composition for the treatment of so-called restless legs A pharmaceutical composition for the treatment of so-called restless legs is disclosed, which composition comprises a combination of: A) quinine, preferably, in the form of a pharmaceutically acceptable acid addition salt thereof; and B) a compound select...	04/10/2001

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Class 514/315 - Piperidines