Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 8173676 | Benzyl, amines, a process for their production and their use as anti-inflammatory agents The present invention relates to the compounds of formula I, processes for their production and their use as anti-inflammatory agents. ... | 05/08/2012 |
| 8106073 | Quinoline derivatives 057 The invention provides a compound of formula (I) as defined in the specification, a process for its preparation, pharmaceutical compositions containing it, a process for preparing the pharmaceutical composition, and its use in therapy. ... | 01/31/2012 |
| 8088795 | Cyclic-alkylamine derivatives as inhibitors of the interaction between MDM2 and p53 The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, t, R1, R2, R3, R4 | 01/03/2012 |
| 8076358 | 6-substituted-thio-2-amino-quinoline derivatives useful as inhibitors of β-secretase (BACE) The present invention is directed to 6-substituted-thio-2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD), mild cognitive impairment, senility and/or dementia. The compounds of the p... | 12/13/2011 |
| 8071621 | Alkylsulphonamide quinolines Compounds of Formula I wherein R1, A, R2, R3, R4, R5, R8, n, m, q and r are as described in the specification, pharmaceutically-acceptable salts, methods of ... | 12/06/2011 |
| 8053446 | Cyanoguanidine compounds Novel pyridyl cyanoguanidine compounds of general formula I (I) wherein R1, X, R2 and R3 are as defined herein, exhibit a high antiproliferative activity and may be used in the treatment of hyperproliferative and neo-plastic diseases... | 11/08/2011 |
| 7964616 | Compounds 679 The invention provides compounds of formula (I), processes for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy, wherein R1, R2, R3 and ... | 06/21/2011 |
| RE42376 | Substituted 3-cyanoquinolines This invention provides compounds of formula I having the structure wherein G1, G2, R1, R4, Z, n, and X are defined in the specification or a pharmaceutically acceptable salt ther... | 05/17/2011 |
| 7939546 | Quinoline derivatives for modulating DNA methylation Quinoline derivatives, particularly 4-(4-(4-(quinolin-4-ylamino)benzamido)phenylthio)pyrrolidine-2-carboxylic acid; 3-(4-(4-(quinolin-4-ylamino)benzamido)phenylthio)pyrrolidine; N-(4-(piperidin-4-ylthio)phenyl)-4-(quinolin-4-ylamino)-benzamide; and N-(4-(piperidin-3... | 05/10/2011 |
| 7928123 | Compounds which modulate the CB2 receptor Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are... | 04/19/2011 |
| 7884113 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators The invention provides for compounds of formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for t... | 02/08/2011 |
| 7868022 | 2-amino-quinoline derivatives useful as inhibitors of β-secretase (BACE) The present invention is directed to 2-amino-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also know... | 01/11/2011 |
| 7863295 | Treatments for neuropathy Small fiber neuropathy is treated by topically administering to a subject in need thereof topically active quinoline compounds or pharmaceutically acceptable salts thereof under conditions effective to treat neuropathy in the subject. Glial cell-derived neurotrophic... | 01/04/2011 |
| 7799803 | Hydroxamic acid compounds and methods of use thereof The present invention relates to a novel class of hydroxamic acid derivatives having at least two aryl containing groups, at least one of which is a quinolinyl, isoquinolinyl or benzyl moiety, linked to the hydroxamic acid group through a methylene chain. The hydrox... | 09/21/2010 |
| 7790746 | Quinoline derivatives for modulating DNA methylation Quinoline derivatives, particularly 4-anilinoquinoline derivatives of formula (I), are provided: Such quinoline derivatives can be used for modulation of DNA methylation, such as effective inhibition of methylation of cytos... | 09/07/2010 |
| 7781458 | Derivatives of pyridine and quinoline The invention provides compounds of formula I blocking phosphorylcholine biosynthesis by means of the selective blocking of the choline kinase enzyme in tumor cells or in cells affected by parasitic infection and therefore being applicable in the treatment of tumors... | 08/24/2010 |
| 7776882 | 2-amino-3,4-dihydro-quinoline derivatives useful as inhibitors of β-secretase (BACE) The present invention is directed to 2-amino-3,4-dihydro-quinoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretas... | 08/17/2010 |
| 7683076 | Tetrahydro-quinolinylurea derivatives This invention relates to tetrahydro-quinolinylurea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The tetrahydro-quinolinylurea derivative of the present invention has vanilloid receptor (VR1) antagonistic activ... | 03/23/2010 |
| 7618986 | Method of treating latent tuberculosis 2-Nitroimidazolyl-alkylaminoquinolines, and compositions containing the same, useful in the treatment of tuberculosis are disclosed. Methods of treating tuberculosis using the 2-nitroimidazolyl-alkylaminoquinolines, and compositions containing the same, also are dis... | 11/17/2009 |
| 7608628 | Alkylsulphonamide quinolines Compounds of Formula II wherein R1, A, R2, R3, R4, R5, R8, n, m and q are as described in the specification, pharmaceutically-acceptable salts, methods of ma... | 10/27/2009 |
| 7585878 | Benzamide derivative or salt thereof There is provided a compound having a capsaicin receptor VR1 inhibitory activity and useful as a therapeutic agent for various pains including inflammatory pain and neurogenic pain, migraine, cluster headache, bladder diseases including overactive bladder, and the l... | 09/08/2009 |
| 7550483 | Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same An amorphous form of a salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide. ... | 06/23/2009 |
| 7550482 | Tetrahydroquinolones and their use as modulators of metabotropic glutamate receptors The invention relates to ethynyl-substituted tetrahydroquinolinone derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are group I mGluR modu... | 06/23/2009 |
| 7531554 | 4-oxoquinoline compound and use thereof as HIV integrase inhibitor Provision of a compound having an anti-HIV activity, particularly an integrase inhibitory activity. A 4-oxoquinoline compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof: wh... | 05/12/2009 |
| 7524862 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds Alkyne compounds of formula I wherein A, B, W, X, Y, Z, R1, and R2 have the meanings given herein, which have MCH-receptor antagonistic activity and are useful for preparing pharmaceutical compositions... | 04/28/2009 |
| 7507750 | Stabilized ascorbic acid derivative An ascorbic acid derivative, which is a compound represented by the following general formula (1) or a salt thereof: [Chemical Formula 11] (wherein X and Y each represents H or a protective group for OH, R1 | 03/24/2009 |
| 7488740 | Substituted quinolin-4-ylamine analogues Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation... | 02/10/2009 |
| 7468379 | Inhibition of osteolytic lesions by SRC kinase inhibitors The present invention include methods and compositions for treating bone-resorbing diseases or bone resorption related to a pathologic condition generally, including, but not limited to osteoporosis, arthritis, rheumatoid arthritis, cancer metastases to the bone, bo... | 12/23/2008 |
| 7449479 | Hepatitis C virus inhibitors Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R′, B, Y and X are described in the description. Compositions comprising the compounds an... | 11/11/2008 |
| 7442710 | Substituted phenyl methanones The present invention relates to compounds of general formula IA or IB wherein X1 and X2 are each independently N or C—R″ and R1, R2,R3, R... | 10/28/2008 |
| 7425564 | Quinoline derivative and quinazoline derivative inhibiting self-phosphorylation of hepatocytus prolifertor receptor and medicinal composition containing the same An objective of the present invention is to provide compounds having potent antitumor activity. The compounds of the present invention are represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof: ... | 09/16/2008 |
| 7417056 | 5-substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents Compounds of general formula (IIa) or (IIb) and their use as pharmaceutical agents. ... | 08/26/2008 |
| 7417148 | 4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML) Compounds of the formula: wherein: n is an integer from 1-3; X is N, CH, provided that when X is N, n is 2 or 3; R is alkyl of 1 to 3 carbon atoms; R1 is 2,4... | 08/26/2008 |
| 7414037 | Hydrazide-containing CFTR inhibitor compounds and uses thereof The invention provides compositions, pharmaceutical preparations and methods for inhibition of cystic fibrosis transmembrane conductance regulator protein (CFTR) that are useful for the study and treatment of CFTR-mediated diseases and conditions. The compositions a... | 08/19/2008 |
| 7402674 | 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments The invention relates to 7-phenylamino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically... | 07/22/2008 |
| 7402683 | Cinnamic acid amides The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection. ... | 07/22/2008 |
| RE40418 | Treatment of neoplasms with CCI-779/EKB-569 combination This invention provides the use of a combination of CCI-779 and EKB-569 in the treatment of neoplasms. ... | 07/01/2008 |
| 7384958 | Quinoline inhibitors of cGMP phosphodiesterase Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5. ... | 06/10/2008 |
| 7378430 | Quinoline inhibitors of cGMP phosphodiesterase Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5. ... | 05/27/2008 |
| 7371731 | Methods for using glucose pentasulfate for treating amyloid associated with type II diabetes A pharmaceutical agent for treating an amyloid disease in a patient, wherein the pharmaceutical agent comprises glucose pentasulfate or a pharmaceutically acceptable salt thereof. The agent is directed to amyloid diseases in general and to type II diabetes in partic... | 05/13/2008 |
